Olivier Pertz
@olivierpertz.bsky.social
Prof at University of Bern
#MAPK #Rho #optogenetics #biosensors #computer_vision
skiing, rock/ice/mountain climbing when I have time
#MAPK #Rho #optogenetics #biosensors #computer_vision
skiing, rock/ice/mountain climbing when I have time
Had the Kapitein lab in Bern for a retreat about smart microscopy for optogenetics - a lot of science, walking up the hill to look at our beautiful mountains and even a Jazz concert.
Outcome: new ideas, tired brains, and the beginning of something awesome.
Can’t wait for round 2 in Utrecht
Outcome: new ideas, tired brains, and the beginning of something awesome.
Can’t wait for round 2 in Utrecht
November 19, 2025 at 5:31 PM
Had the Kapitein lab in Bern for a retreat about smart microscopy for optogenetics - a lot of science, walking up the hill to look at our beautiful mountains and even a Jazz concert.
Outcome: new ideas, tired brains, and the beginning of something awesome.
Can’t wait for round 2 in Utrecht
Outcome: new ideas, tired brains, and the beginning of something awesome.
Can’t wait for round 2 in Utrecht
Reposted by Olivier Pertz
Why do whales and elephants have much lower rates of cancer than expected?
"Species with a lower cancer prevalence and mortality
risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:"
www.science.org/doi/10.1126/...
"Species with a lower cancer prevalence and mortality
risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:"
www.science.org/doi/10.1126/...
Coevolution of cooperative lifestyles and reduced cancer prevalence in mammals
While cooperative mammals evolve reducing cancer prevalence, oncogenes can be maintained by selection in competitive species.
www.science.org
November 15, 2025 at 4:43 PM
Why do whales and elephants have much lower rates of cancer than expected?
"Species with a lower cancer prevalence and mortality
risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:"
www.science.org/doi/10.1126/...
"Species with a lower cancer prevalence and mortality
risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:"
www.science.org/doi/10.1126/...
Reposted by Olivier Pertz
A game changer in our hands... www.nature.com/articles/s41...
Universal consensus 3D segmentation of cells from 2D segmented stacks - Nature Methods
u-Segment3D is a universal framework that translates and enhances 2D instance segmentations to a 3D consensus instance segmentation without training data. It performs well across diverse datasets, inc...
www.nature.com
November 11, 2025 at 6:48 PM
A game changer in our hands... www.nature.com/articles/s41...
This Wednesday @bgraedel.bsky.social defended his PhD — crowning an extraordinary scientific journey.
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
November 7, 2025 at 12:15 PM
This Wednesday @bgraedel.bsky.social defended his PhD — crowning an extraordinary scientific journey.
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
He showed how live-cell imaging and computational modeling can reveal and perturb cytoskeletal dynamics at micrometer and second-level scales.
Thanks Benjamin — a wild, inspiring ride! 🚀
Reposted by Olivier Pertz
Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated image analysis pipeline! 🐟🔬📊
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
October 29, 2025 at 2:20 PM
Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated image analysis pipeline! 🐟🔬📊
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Huge kudos to Max Hess for this PhD milestone! 💪
@lucaspelkmans.bsky.social shorturl.at/cO0u7
Let's zoom in!
Excited to join the Fusion Conference on Fibroblast Growth Factor Signalling this May in Malta 🇲🇹!
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
Fibroblast Growth Factor Signalling in Development, Health & Disease Conference | Fusion Conferences
Receptor Tyrosine Kinases (RTKs) are cell-surface receptors that, upon ligand binding, regulate cell-to-cell communication during embryonic development and in adult life. Among RTKs, the twenty-two Fi...
www.fusion-conferences.com
October 21, 2025 at 12:20 PM
Excited to join the Fusion Conference on Fibroblast Growth Factor Signalling this May in Malta 🇲🇹!
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
I’ll be discussing how FGF–MAP kinase signaling unfolds at the single-cell level — bridging molecules to cell decisions 🔬✨
#FGF #MAPK #conference www.fusion-conferences.com/conference/195
Went to see Yayoi Kusama’s mind-bending art at the Beyeler Foundation in Basel. As a biologist, I tried to enjoy the art… but my brain kept yelling "nuclei!", “organoid!”, and “endocytosis!”. Here are some of my favorite accidental biology sightings. 🧬🎨🧫
October 19, 2025 at 8:11 PM
Went to see Yayoi Kusama’s mind-bending art at the Beyeler Foundation in Basel. As a biologist, I tried to enjoy the art… but my brain kept yelling "nuclei!", “organoid!”, and “endocytosis!”. Here are some of my favorite accidental biology sightings. 🧬🎨🧫
Reposted by Olivier Pertz
Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
October 1, 2025 at 9:43 AM
Want to get started with smart microscopy? 🧠🔬
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Check out our online repository with implementations from labs and industry -- lots of practical tips and links to sample code! smartmicroscopy.github.io/implementati...
More details in the ✨updated preprint!✨
www.biorxiv.org/content/10.1...
Reposted by Olivier Pertz
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
September 23, 2025 at 11:04 PM
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
Reposted by Olivier Pertz
Its raining #Ichthyos ... Hallelujah!
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
September 15, 2025 at 7:52 AM
Its raining #Ichthyos ... Hallelujah!
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
#Lattice #LightSheet #Ichthyosporeans #Creolimax #Cellularization #ProtistsOnSky
so happy to have Katie as a colleague !
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks
at the University of Bern, Switzerland.
www.cell.com
September 10, 2025 at 3:45 PM
so happy to have Katie as a colleague !
Reposted by Olivier Pertz
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
Catherine Peichel
Interview with Katie Peichel, who studies the evolutionary genetics of sticklebacks
at the University of Bern, Switzerland.
www.cell.com
September 9, 2025 at 2:36 PM
Nice interview to Katie Peichel @currentbiology.bsky.social
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
I completely agree with her claims for more funding for curiosity-driven research, basic Science... Science.
www.cell.com/current-biol...
looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !
Preprint alert!
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength.
doi.org/10.1101/2025...
September 9, 2025 at 7:20 PM
looks like an ingenious combination of technologies to study out of equilibrium developmental processes ... Congrats !
⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern!
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) - Bern, Switzerland job with University of Bern, Institute of Cell Biology | 12840798
Assistant Professor with tenure-track for Quantitative Cell Biology (80-100%) at the University of Bern, Switzerland.
shorturl.at
September 9, 2025 at 3:32 PM
⚡️ Don’t forget that we’re looking for a Tenure-track Assistant Professor in Quantitative Cell Biology @ UniBern!
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
🔬 Bridge experiments + theory
📈 Tackle processes across scales
💡 Join our vibrant research community
Deadline Oct 17 👉 shorturl.at/1Y1WP
Reposted by Olivier Pertz
Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Seminars in Cell & Developmental Biology | Novel functions of programmed cell death in development: current status and future challenges | ScienceDirect.com by Elsevier
While the core regulators of programmed cell death have been relatively well characterised, our understanding of the regulation and role of programmed cell death in tissue during embryonic development...
www.sciencedirect.com
August 28, 2025 at 10:58 AM
Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Reposted by Olivier Pertz
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social
ucd.ie/sbi/news/new...
ucd.ie/sbi/news/new...
August 27, 2025 at 2:59 PM
2 weeks ago we were some of the first to see 'Cancer Revolution: Science, Innovation & Hope,' the astounding new exhibition from Breakthrough Cancer Research. Read more about this free interactive display & our involvement in the project along w/ @precisiononcire.bsky.social
ucd.ie/sbi/news/new...
ucd.ie/sbi/news/new...
“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 22, 2025 at 2:41 PM
“New paper out 🎉 We built a system to automate optogenetic cell control across scales. For the demo, we made the cells spell my name — because if you can’t use science to feed your ego, what’s the point? 😎🧫✨”
Reposted by Olivier Pertz
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
August 21, 2025 at 8:16 PM
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out! www.biorxiv.org/content/10.1...
Congrats @lhinderling.bsky.social and team
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
August 22, 2025 at 2:38 PM
Congrats @lhinderling.bsky.social and team
Reposted by Olivier Pertz
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
August 21, 2025 at 2:22 PM
So many people involved! Special thanks to @hannah-superres.bsky.social, Alfredo Rates, @olivierpertz.bsky.social, @nilsnorlin.bsky.social, Aliaksandr Halavatyi & Rafael Camacho. Link again to the paper: www.biorxiv.org/content/10.1...
Reposted by Olivier Pertz
Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:
August 21, 2025 at 2:22 PM
Not only acquisition settings can be changed, but also perturbation: Popular is automated targeting of photomanipulation:
Reposted by Olivier Pertz
For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎
August 21, 2025 at 2:22 PM
For example event-driven acquisition: rare events (here mitoses) are detected in a low-res overview scan, the microscope switches objective to automatically image only the mitotic cells in high-res. 🔎
Reposted by Olivier Pertz
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
August 21, 2025 at 2:22 PM
🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:
Reposted by Olivier Pertz
In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology
The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...
pubs.rsc.org
August 6, 2025 at 9:33 AM
In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social.
Read now: pubs.rsc.org/en/content/a...
Reposted by Olivier Pertz
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...
August 4, 2025 at 6:42 AM
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...