Renal Pathology Society (RPS)
@renalpathsociety.bsky.social
BlueSky account of the Renal Pathology Society (RPS) #renalpath
https://www.renalpathsoc.org/
https://www.renalpathsoc.org/
Reposted by Renal Pathology Society (RPS)
The RPS is inviting you to a webinar
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
November 22, 2025 at 8:14 PM
The RPS is inviting you to a webinar
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Reposted by Renal Pathology Society (RPS)
Join RPS-GlomCon Renal Pathology Webinar Series
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
November 18, 2025 at 1:45 AM
Join RPS-GlomCon Renal Pathology Webinar Series
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Reposted by Renal Pathology Society (RPS)
Unusual granular casts with annular appearance. Light chain, hemoglobin, myoglobin, chromogranin casts excluded. Patient on IV vancomycin. Suspicious for vancomycin cast nephropathy. pubmed.ncbi.nlm.nih.gov/31871855/ #renalpath #pathsky #nephsky
November 21, 2025 at 3:11 PM
Unusual granular casts with annular appearance. Light chain, hemoglobin, myoglobin, chromogranin casts excluded. Patient on IV vancomycin. Suspicious for vancomycin cast nephropathy. pubmed.ncbi.nlm.nih.gov/31871855/ #renalpath #pathsky #nephsky
Reposted by Renal Pathology Society (RPS)
Unfortunate but not rare IgAN presentation. Pt in their 30's, no PMHx, presented with HTN emergency, CKD, hematuria, proteinuria. Advanced IgAN with severe IFTA, focal active crescents (M1 E1 S1 T2 C1). Wish we could catch these cases earlier. #renalpath #pathsky #nephsky
November 23, 2025 at 3:50 PM
Unfortunate but not rare IgAN presentation. Pt in their 30's, no PMHx, presented with HTN emergency, CKD, hematuria, proteinuria. Advanced IgAN with severe IFTA, focal active crescents (M1 E1 S1 T2 C1). Wish we could catch these cases earlier. #renalpath #pathsky #nephsky
Reposted by Renal Pathology Society (RPS)
Diagnosis unmasked. Young F with 2g proteinuria, weak +dsDNA. Membranous pattern, IF with C3 dominant staining. Pronase IF --> IgG-k. Membranous-like glomerulopathy with masked monotypic IgG-k deposits. Considered to be autoimmune; not MGRS. #renalpath #pathsky #nephsky.
November 20, 2025 at 1:01 PM
Diagnosis unmasked. Young F with 2g proteinuria, weak +dsDNA. Membranous pattern, IF with C3 dominant staining. Pronase IF --> IgG-k. Membranous-like glomerulopathy with masked monotypic IgG-k deposits. Considered to be autoimmune; not MGRS. #renalpath #pathsky #nephsky.
Reposted by Renal Pathology Society (RPS)
#RenalPath: C1q nephropathy w. segmental sclerosis w. increased mesangial matrix, obliteration of capillary lumens, adhesion to Bowman capsule (right half of tuft) Open left portion of glomerulus shows mild to moderate increase in mesangial cellularity
bit.ly/3XadOLx
bit.ly/3XadOLx
November 23, 2025 at 5:00 PM
#RenalPath: C1q nephropathy w. segmental sclerosis w. increased mesangial matrix, obliteration of capillary lumens, adhesion to Bowman capsule (right half of tuft) Open left portion of glomerulus shows mild to moderate increase in mesangial cellularity
bit.ly/3XadOLx
bit.ly/3XadOLx
Reposted by Renal Pathology Society (RPS)
#Quiz from October 2025:
A 16-year-old male patient presented to an ED with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/47iQnEo
A 16-year-old male patient presented to an ED with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/47iQnEo
November 22, 2025 at 11:00 AM
#Quiz from October 2025:
A 16-year-old male patient presented to an ED with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/47iQnEo
A 16-year-old male patient presented to an ED with a 3-week history of progressive headaches, nausea, vomiting, and bilateral blurry vision. Over the past 3 days, he developed chest pain and shortness of breath.
bit.ly/47iQnEo
Reposted by Renal Pathology Society (RPS)
Hilar variant of focal segmental glomerulosclerosis, with segmental sclerosis at the vascular pole with hyalinosis and adhesion (Jones silver stain)
bit.ly/49P5wQP (FREE)
#FSGS #renalpath
bit.ly/49P5wQP (FREE)
#FSGS #renalpath
November 21, 2025 at 11:00 AM
Hilar variant of focal segmental glomerulosclerosis, with segmental sclerosis at the vascular pole with hyalinosis and adhesion (Jones silver stain)
bit.ly/49P5wQP (FREE)
#FSGS #renalpath
bit.ly/49P5wQP (FREE)
#FSGS #renalpath
Reposted by Renal Pathology Society (RPS)
#UrinarySediment from a pt with #AKI #RPGN due to suspected MPO-AAV-GN inspected with Sternheimer stain: WBC cast (bright field), broad RBC cast (bright), waxy cast (bright), and granular cast w/Ca Oxalate monohydrate crystals (oblique). #OchsnerNephrology #UrineMicroscopy
November 22, 2025 at 9:31 PM
#UrinarySediment from a pt with #AKI #RPGN due to suspected MPO-AAV-GN inspected with Sternheimer stain: WBC cast (bright field), broad RBC cast (bright), waxy cast (bright), and granular cast w/Ca Oxalate monohydrate crystals (oblique). #OchsnerNephrology #UrineMicroscopy
The RPS is inviting you to a webinar
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
November 22, 2025 at 8:14 PM
The RPS is inviting you to a webinar
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Tuesday, December 2, 2025
8:00 AM PST / 11:00 AM EST / 5:00 PM CET
For more info & to register: renalpathsoc.org/event-6445938
#renalpath #PathTwitter #nephrology
Reposted by Renal Pathology Society (RPS)
BK nephropathy
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
November 19, 2025 at 3:35 PM
BK nephropathy
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Clues:
- Heavy but focal tubulointerstitial inflammation
- Increased plasma cells
- Viral cytopathic change
- Features of CNI toxicity ->over immunosuppression (isometric vacuolization shown here)
-SV40 IHC confirmatory
#renalpath #pathsky #nephsky
Reposted by Renal Pathology Society (RPS)
Urine crystals in a patient with Crohn’s
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
November 19, 2025 at 5:40 PM
Urine crystals in a patient with Crohn’s
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Answer: www.kidney-international.org/article/S008... in @kidneyint.bsky.social
#NephSky
Reposted by Renal Pathology Society (RPS)
Arteriole with features of a old recanalized thombus in a transplant kidney biopsy. Multiple slit like vascular spaces within the fibrotic lumen. Not a lesion I see often. Pt had clinically diagnosed TMA a few months prior. #renalpath #pathsky #nephsky
November 18, 2025 at 6:29 PM
Arteriole with features of a old recanalized thombus in a transplant kidney biopsy. Multiple slit like vascular spaces within the fibrotic lumen. Not a lesion I see often. Pt had clinically diagnosed TMA a few months prior. #renalpath #pathsky #nephsky
Join RPS-GlomCon Renal Pathology Webinar Series
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
November 18, 2025 at 1:45 AM
Join RPS-GlomCon Renal Pathology Webinar Series
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Update on CKDu/CINAC
Speaker: Cynthia Nast, MD
Date: November 30, 2025
Webinar info: renalpathsoc.org/event-6113942
#renalpath #PathTwitter
@glomcon.org
Reposted by Renal Pathology Society (RPS)
IgA Vasculitis
A kidney biopsy is mandatory in patients with persistent proteinuria ≥0.5 g/day for more than 4 weeks, impaired kidney function, or suspicion of rapidly progressive glomerulonephritis (RPGN).
#NephJC
A kidney biopsy is mandatory in patients with persistent proteinuria ≥0.5 g/day for more than 4 weeks, impaired kidney function, or suspicion of rapidly progressive glomerulonephritis (RPGN).
#NephJC
October 29, 2025 at 1:43 AM
IgA Vasculitis
A kidney biopsy is mandatory in patients with persistent proteinuria ≥0.5 g/day for more than 4 weeks, impaired kidney function, or suspicion of rapidly progressive glomerulonephritis (RPGN).
#NephJC
A kidney biopsy is mandatory in patients with persistent proteinuria ≥0.5 g/day for more than 4 weeks, impaired kidney function, or suspicion of rapidly progressive glomerulonephritis (RPGN).
#NephJC
Reposted by Renal Pathology Society (RPS)
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles
#nephrology #nephsky
link.springer.com/article/10.1...
#nephrology #nephsky
link.springer.com/article/10.1...
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles - Pediatric Nephrology
Background Rituximab is considered a therapeutic option in children with refractory nephrotic syndrome (RNS). However, the efficacy and safety of rituximab treatment remain unclear. Objective This stu...
link.springer.com
November 8, 2025 at 2:48 PM
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles
#nephrology #nephsky
link.springer.com/article/10.1...
#nephrology #nephsky
link.springer.com/article/10.1...
Reposted by Renal Pathology Society (RPS)
AJKD Atlas of Renal Pathology: Crystalglobulin-Induced Nephropathy
bit.ly/41jvO7T (FREE)
#RenalPath
Image: Large bright eosinophilic crystals within glomerular capillaries (arrow, Jones silver stain)
bit.ly/41jvO7T (FREE)
#RenalPath
Image: Large bright eosinophilic crystals within glomerular capillaries (arrow, Jones silver stain)
November 11, 2025 at 11:00 PM
AJKD Atlas of Renal Pathology: Crystalglobulin-Induced Nephropathy
bit.ly/41jvO7T (FREE)
#RenalPath
Image: Large bright eosinophilic crystals within glomerular capillaries (arrow, Jones silver stain)
bit.ly/41jvO7T (FREE)
#RenalPath
Image: Large bright eosinophilic crystals within glomerular capillaries (arrow, Jones silver stain)
Reposted by Renal Pathology Society (RPS)
Novel Treatment Paradigms: #Complement #Inhibition in Antineutrophil Cytoplasmic Autoantibody Vasculitis
https://doi.org/10.1016/j.ekir.2025.07.015
#KIRReview #ANCA
https://doi.org/10.1016/j.ekir.2025.07.015
#KIRReview #ANCA
November 13, 2025 at 1:01 PM
Novel Treatment Paradigms: #Complement #Inhibition in Antineutrophil Cytoplasmic Autoantibody Vasculitis
https://doi.org/10.1016/j.ekir.2025.07.015
#KIRReview #ANCA
https://doi.org/10.1016/j.ekir.2025.07.015
#KIRReview #ANCA
Reposted by Renal Pathology Society (RPS)
Should nephrologists further implement genetic testing in patients with CKD? In this #ASNJASN study of adult CKD management, genetic testing showed diagnostic and clinical utility in the year following the reporting of test results. Read more: kidney.pub/JASN0913
November 15, 2025 at 6:00 PM
Should nephrologists further implement genetic testing in patients with CKD? In this #ASNJASN study of adult CKD management, genetic testing showed diagnostic and clinical utility in the year following the reporting of test results. Read more: kidney.pub/JASN0913
Reposted by Renal Pathology Society (RPS)
November 16, 2025 at 11:00 AM
Reposted by Renal Pathology Society (RPS)
Review by Anthony Bleyer et al:
Autosomal Dominant Tubulointerstitial Kidney Disease: A Review
bit.ly/3VgPMNS (FREE)
Autosomal Dominant Tubulointerstitial Kidney Disease: A Review
bit.ly/3VgPMNS (FREE)
November 16, 2025 at 11:00 PM
Review by Anthony Bleyer et al:
Autosomal Dominant Tubulointerstitial Kidney Disease: A Review
bit.ly/3VgPMNS (FREE)
Autosomal Dominant Tubulointerstitial Kidney Disease: A Review
bit.ly/3VgPMNS (FREE)
Reposted by Renal Pathology Society (RPS)
Illustrative example of a segmental membranous nephropathy pattern (segmental granular IgG staining) which is often seen with NELL-1+ (IHC) MN as in this case. Deposits present in only some loops by EM. #renalpath #pathsky #nephsky
November 17, 2025 at 8:03 PM
Illustrative example of a segmental membranous nephropathy pattern (segmental granular IgG staining) which is often seen with NELL-1+ (IHC) MN as in this case. Deposits present in only some loops by EM. #renalpath #pathsky #nephsky
Reposted by Renal Pathology Society (RPS)
NELL-1 IHC can also be tricky to interpret as there is significant podocyte cytoplasmic staining in the negative control. Must show granular capillary wall deposits which match deposits by IF and EM. #renalpath #pathsky #nephsky
November 17, 2025 at 8:06 PM
NELL-1 IHC can also be tricky to interpret as there is significant podocyte cytoplasmic staining in the negative control. Must show granular capillary wall deposits which match deposits by IF and EM. #renalpath #pathsky #nephsky
Reposted by Renal Pathology Society (RPS)
Chronic active ABMR in patient with worsening proteinuria, renal function, positive DSA
*Glomerulitis (shown in image)
*Transplant glomerulopathy (shown in image)
*Peritubular capillaritis
*Diffuse C4d+ in PTCs on IF
#renalpath #transplant #pathsky #nephsky #medsky
*Glomerulitis (shown in image)
*Transplant glomerulopathy (shown in image)
*Peritubular capillaritis
*Diffuse C4d+ in PTCs on IF
#renalpath #transplant #pathsky #nephsky #medsky
April 7, 2025 at 3:50 AM
Chronic active ABMR in patient with worsening proteinuria, renal function, positive DSA
*Glomerulitis (shown in image)
*Transplant glomerulopathy (shown in image)
*Peritubular capillaritis
*Diffuse C4d+ in PTCs on IF
#renalpath #transplant #pathsky #nephsky #medsky
*Glomerulitis (shown in image)
*Transplant glomerulopathy (shown in image)
*Peritubular capillaritis
*Diffuse C4d+ in PTCs on IF
#renalpath #transplant #pathsky #nephsky #medsky
Reposted by Renal Pathology Society (RPS)
#RenalPath: Antibody-mediated acute rejection with glomerulitis: increased intracapillary leukocytes (arrows) in glomerular tuft (Jones silver stain).
bit.ly/2uShEyu (FREE)
bit.ly/2uShEyu (FREE)
August 17, 2025 at 10:02 AM
#RenalPath: Antibody-mediated acute rejection with glomerulitis: increased intracapillary leukocytes (arrows) in glomerular tuft (Jones silver stain).
bit.ly/2uShEyu (FREE)
bit.ly/2uShEyu (FREE)