Italian scientists develop a lithium nasal spray using gold nanoparticles to safely target the brain and treat Alzheimer’s and bipolar disorder.

Elevated calcium levels in the blood—a complication of kidney cancers known as hypercalcemia—may be successfully treated with a class of medications called HIF-2α inhibitors developed by UT Southweste...

Membranoproliferative glomerulonephritis (MPGN) is currently stratified into complement C3 glomerulopathy (C3G) and immune complex-mediated MPGN (IC-MPGN). However, classification is subject to contin...

Bashu features in an episode of Heartstopper when a lead character celebrates his birthday at a zoo.

Proteinuria is predictive for kidney disease progression and used as treatment indication. It is avoided by reabsorption of filtered proteins by megalin and the cubilin-amnionless complex (CUBAM) in t...

Achieving donor-specific immune tolerance has the potential to eliminate the need for lifelong immunosuppression in transplant recipients, but translating th...

Nature Reviews Neurology, Published online: 01 October 2025; doi:10.1038/s41582-025-01150-2A new study presented at the 2025 American Neurological Association Annual Meeting indicates that area postrema syndrome in people with neuromyelitis optica spectrum disorder is related to elevated levels of the gut hormone glucagon-like peptide 1 and its receptor GLP-1R.

The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

AbstractBACKGROUND. Refractory hypertension (RfHTN), a phenotype of antihypertensive treatment failure, is defined as uncontrolled automated office blood p

Despite advances in targeted therapies, treatment with glucocorticoids remains a mainstay in the management of various immune-mediated diseases. High cumulative doses of exogenous glucocorticoids lead...

New preclinical data demonstrate deeper IgA reduction and a longer half-life compared to first-generation anti-APRIL monoclonal antibody CLYM116 Phase 1 trial initiation expected in Q4 2025, with init...

Abstract. Primary aldosteronism (PA) is the most common endocrine hypertension. For decades, PA diagnosis has required proving nonsuppressibility of aldost

Recipient diagnosed with brain death received a type-O organ, which is compatible with all blood types.