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samuelconnell.bsky.social
Sam Connell
@samuelconnell.bsky.social
2.9K followers 8.5K following 830 posts
Scientist and Global Sales Director at 3i (@the.3i.social), foodie, family man. Tai Chi and meditation matter. Compassion Heals. Microscopes Rock. https://www.intelligent-imaging.com
Posts Replies Media Videos
Reposted by Sam Connell
jbwallingford.bsky.social
Cilia alert! Stoked to have the new paper from Juyeon Hong about a new domain at the extreme distal tip of motile cilia! (The EDT, y'all!) It's out now @natcomms.nature.com.
Check it out!
#cilia

www.nature.com/articles/s41...
A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function - Nature Communications
Here they combine in vivo imaging with proteomics to characterize a protein complex comprised of Ccdc78 and Ccdc33 that acts at the extreme distal tip of 9 + 2 motile cilia to control tip architecture...
www.nature.com
January 29, 2026 at 1:23 AM
Reposted by Sam Connell
rangarajuvidhya.bsky.social
Looking forward to sharing our lab's latest, exciting results on how the brain is powered 🧠 🔋 🪫 🔬 🧪
#Sunposium2026 @mpfneuro.bsky.social
January 28, 2026 at 7:47 PM
Reposted by Sam Connell
gwgl.bsky.social
The call for session proposals for Cell Bio 2026 is open. ASCB gives priority to organizers who haven't run a session in the last two years, and they encourage trainees to submit with an experienced co-chair. Deadline: Feb 22. @ascbiology.bsky.social www.ascb.org/cellbio2026/...
Cell Bio 2023-An ASCB|EMBO Meeting
Network, learn, and collaborate with top cell biologists from around the globe.
www.ascb.org
January 28, 2026 at 11:36 PM
Reposted by Sam Connell
gbaucom.bsky.social
New paper from the lab, stemming from @anahvsb.bsky.social's thesis work, captures a weird trait that totally 🤯 my brain

When Oxalis stricta plants are exposed to a sublethal dose of the herbicide dicamba, they produce MOAR flowers than controls.
Oxalis is a little cute plant that you've probably stepped on
January 28, 2026 at 6:04 PM
Reposted by Sam Connell
senguptalab.bsky.social
Our first 2026 paper is out @currentbiology.bsky.social!
👏 to @nathancsharris.bsky.social (now Asst Prof, GA State) and PD Priya Dutta.

Here we show how transcriptional and trafficking pathways coordinate thermoreceptor levels to precisely modulate response plasticity
www.cell.com/current-biol...
Experience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticity
Harris, Dutta, et al. find that experience-dependent plasticity in the activation threshold of the AFD thermosensory neurons is mediated by modulating warm and cold thermoreceptor levels at the sensor...
www.cell.com
January 28, 2026 at 5:37 PM
Reposted by Sam Connell
markhisted.org
The NIH budget bill passed the House. Now, it's bundled w/ DHS funding in the Senate. We are likely to see a fight this week.

New from me: things to know about the budget bill, NIH presidentialization, free speech, why science has been quiet, & more.

At "Can We Still Govern" @donmoyn.bsky.social 🧪
donmoyn.bsky.social Don Moynihan @donmoyn.bsky.social · 1d
New at Can We Still Govern: NIH scientist @markhisted.org reviews the damage done to American biomedical science in the last year and looks ahead:
"Scientists should not be political partisans, but they should be partisans for liberal democratic principles."🧵
donmoynihan.substack.com/p/american-b...
American biomedical science in 2026
Where we are, how we got here, and what to do next
donmoynihan.substack.com
January 28, 2026 at 1:33 AM
Reposted by Sam Connell
manorlaboratory.bsky.social
Press release on our paper: today.ucsd.edu/story/new-ai...
January 27, 2026 at 8:11 PM
Reposted by Sam Connell
retof.bsky.social
We have two funded postdoctoral positions available. Topics encompass:

-Next gen light-sheet fluorescence microscopy instrumentation

-Structured illumination microscopy and other approaches to extend the resolution limit.

-Nonlinear microscopy combined with adaptive optics / phase conjugation
January 27, 2026 at 10:29 PM
Reposted by Sam Connell
taylordahlin.com
brass solidarity band performing “stand by me” in the streets of whittier next to alex pretti’s memorial. the crowd started chanting “the people united will never be defeated” so they incorporated it into the song. i love minneapolis
January 27, 2026 at 12:22 AM
Reposted by Sam Connell
charlesgaba.com
Blood in the water.

U.S. Sen. John Curtis: Republican of Utah
U.S. Sen. Mike Crapo: Republican of Idaho
Senator John Curtis @SenJohnCurtis You’ve trusted me, and maintaining that trust matters. I’ve worked hard to be your eyes, ears, and voice. We must have a transparent, independent investigation into the Minnesota shooting, and those responsible—no matter their title—must be held accountable. Officials who rush to judgment before all the facts are known undermine public trust and the law-enforcement mission. I disagree with Secretary Noem’s premature DHS response, which came before all the facts were known and weakened confidence. I will be working with a bipartisan group of senators to demand real oversight and transparency, including supporting calls from @RandPaul for leaders of these operations to testify, so trust can be restored and justice served. Senator Mike Crapo Verified @MikeCrapo Any loss of life under politically-charged circumstances is a tragedy. I support a full and impartial investigation into the events leading up to the death of Alex Pretti. His family, law-abiding citizens exercising their Second Amendment right and the trust of the American people deserve a fair process. The Trump Administration has secured our borders after four years of the free flow of illegal immigration that brought an influx of violence, human trafficking and deadly drugs with it. Immigration enforcement is an essential function of our government. ICE has an obligation to enforce U.S. immigration law, and I support its duty to carry out lawful operations to arrest and deport those who pose a public safety risk, including violent offenders. Those duties must be exercised in a way that maintains and restores public trust. Tom Homan’s deployment to Minnesota is a good move. States and cities should work with the Administration to arrest and deport these individuals instead of ratcheting up tension between residents and the federal government by encouraging people to illegally impede ICE’s efforts.
January 27, 2026 at 2:54 AM
Reposted by Sam Connell
joshuasweitz.bsky.social
AFGE represents >800,000 federal workers.

www.afge.org/publication/...
January 27, 2026 at 2:44 AM
Reposted by Sam Connell
chriswarcraft.bsky.social
For any elected official who needs to hear this, I impart a lesson learned from the NFL:

When the other team is tired and on the back foot, you don’t call a timeout so they can catch their breath. You grind their fucking face into the dirt until the final whistle blows and you’ve won the game.
January 27, 2026 at 1:41 AM
Reposted by Sam Connell
faignews.bsky.social
Larry Nance Jr’s shirt at tonight’s Cavs game
January 27, 2026 at 1:14 AM
Reposted by Sam Connell
guijacquemet.bsky.social
🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs).
Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬
Details in thread 🧵👇
#ScienceSky #Postdoc #AcademicJobs Please RT🫶
CELL MIGRATION LAB
We study cell migration in health and disease
cellmig.org
January 21, 2026 at 7:57 AM
Reposted by Sam Connell
thetnholler.bsky.social
COACH KERR: “Their group (the Minnesota Timberwolves) was suffering. It was one of the most bizarre, sad games I’ve ever been a part of.”

(From Anthony Slater)
January 26, 2026 at 3:41 AM
Reposted by Sam Connell
ericcolumbus.bsky.social
Bill Melugin of Fox News may be the best-sourced journalist within ICE and CBP. If he's hearing this, the administration has a real problem.
Bill Melugin @BillMelugin_ NEW: Since yesterday's deadly shooting in MN, I've talked to more than half a dozen federal sources involved immigration enforcement, including several in senior positions, who all tell me they have grown increasingly uneasy & frustrated w/ some of the claims & narratives DHS pushed in the aftermath of the shooting. Specifically, I'm told there is extreme frustration with DHS officials going on TV and putting out statements claiming that Alex Pretti was intending to conduct a "massacre" of federal agents or wanted to carry out "maximum damage", even after numerous videos appeared to show those claims were inaccurate. While they say it was a terrible decision to show up with a gun and inject himself into a federal law enforcement operation, there is no indication Pretti was there to murder law enforcement, as videos appear to show he never drew his holstered firearm. These sources say this messaging from DHS officials has been catastrophic from a PR and morale perspective, as it is eroding trust and credibility - comparing it to when Democrats falsely claimed the border was closed or that Haitians were being whipped at the border. Some of these sources have described DHS’ response to the shooting as “a case study on how not to do crisis PR”, one said they are so “fed up” that they wish they could retire, another said “DHS is making the situation worse”, and another added that “DHS is wrong” and “we are losing this war, we are losing the base and the narrative." These sources all believe this is going to end up being what they call a “bad shoot”, a “shitty” situation that happened in seconds where agents likely heard “gun!”, then the disarmed firearm may have had an accidental discharge that spooked the agents, and they shot. The agents do not have the luxury of multiple slow motion angles - and had to make split second decisions. All of the sources support the mass deportation agenda, but have serious hesitations about the way it is …
January 26, 2026 at 12:55 AM
Reposted by Sam Connell
gregolear.bsky.social
One of the best things I’ve read in a while:
January 25, 2026 at 10:39 PM
Reposted by Sam Connell
iahawks101.bsky.social
Dave Matthews and Tim Ryenolds playing Neil Young’s Ohio last night and ends with some Rage Against the Machine.
January 24, 2026 at 11:35 PM
Reposted by Sam Connell
marcjspears.bsky.social
STATEMENT FROM THE NATIONAL BASKETBALL PLAYERS ASSOCIATION (NBPA) AND ITS EXECUTIVE COMMITTEE ON THE FATAL SHOOTING IN MINNEAPOLIS BY ICE
January 25, 2026 at 8:52 PM
Reposted by Sam Connell
faineg.bsky.social
Absolute banger of a comment on r/military:

www.reddit.com/r/Military/c...
jaderemedy • 4h ago And now comes the most nauseating part of this whole goddamn mess: the hypocrisy. The same loud-mouthed idiots who spent years screaming about tyranny are suddenly dead fucking silent, or worse, cheering, now that it's their side doing it. "ThEy'Re cOminG fOr OuR gUnS!" "GoVerNMenT oVerReAch!" "ShAll nOt bE inFrinGeD!" All that chest-thumping bullshit evaporated the second armed federal agents started terrorizing people they don't like. Let me get this straight: a civilian gets shot dead by federal agents, and the only thing you brainless cunts can muster is "well, DHS says he had a gun"? THAT'S your red line? Guns are sacred when they're strapped to your waist, but magically become a death sentence when they're used as a post-hoc excuse by the government? Either the Second Amendment applies to everyone, or you never believed in it at all. Fucking pick one and own it. This is exactly what tyranny looks like, by the way. Not jackboots marching in formation, but armed agents roaming neighborhoods, stopping people, killing civilians, and then daring the public to question it. Tyranny is execution followed by a press release. Tyranny is labeling the dead a "threat" so the state doesn't have to explain why someone's life just ended in the street. Tyranny is demanding obedience while shredding due process and calling it order. And all you so-called "freedom lovers" are fucking fine with it, as long as it's brown people, immigrants, protesters, or anyone you've already dehumanized. Turns out "don't tread on me" actually meant "tread on them." You weren't afraid of tyranny. You were afraid of losing dominance. There's a difference, and this moment exposes it completely. "Just comply" isn't a principle. It's cowardice dressed up as common sense. It's the language of people who have already accepted that the state gets to decide who deserves rights and who doesn't. And once you make that deal, don't act shocked when the line moves, because it always fuckin…
January 25, 2026 at 1:33 AM
Reposted by Sam Connell
brooklynspoke.bsky.social
As a Disney Parks nerd, I follow dozens of Disney influencers on Instagram and a whole lot of them are posting about abolishing ICE. The idea has broken containment.
cwarzel.bsky.social Charlie Warzel @cwarzel.bsky.social · 4d
man the stuff i am seeing on IG from
the most normie, i don’t really talk about politics accounts suggests something different
January 25, 2026 at 2:29 AM
Reposted by Sam Connell
billkristolbulwark.bsky.social
Also, may I say that I don’t agree with people saying ICE and CBP need “more training.” They’re doing exactly what this administration has trained them to—impose a reign of fear in blue cities. They don’t need more training. They need to be ripped up root and branch.
January 24, 2026 at 11:01 PM
Reposted by Sam Connell
katiephang.bsky.social
This is a MUST-READ affidavit.

This eyewitness to Alex Pretti’s murder — who is too scared to even go home because she doesn’t trust federal agents — directly refutes what the feds are saying happened today:
January 25, 2026 at 1:59 AM
Reposted by Sam Connell
jeffrueter.bsky.social
Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti.

"Please get the truth out about our son."
Statement from Michael and Susan Pretti Parents of Alex Jeffrey Pretti “We are heartbroken but also very angry. Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact. I do not throw around the ‘hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed. Please get the truth out about our son. He was a good man. Thank you.
January 25, 2026 at 12:43 AM