@sarasuliman.bsky.social
83 followers 180 following 56 posts
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sarasuliman.bsky.social
I've had some of the best years working with SATVI in Cape Town. I haven't left the TB field because of how inspiring that period is my life was. If you want to do infectious disease work that counts, apply!
tomscriba.bsky.social
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:

idm.uct.ac.za/media/739223
sarasuliman.bsky.social
With everything happening, I might apply Tom 😂
Reposted
asm.org
ASM @asm.org · 1d
In a new opinion piece in @statnews.com ASM member Sarah Stanley, Ph.D., emphasizes that safe gain-of-function research is essential to identifying new treatments for diseases like tuberculosis—yet the NIH has imposed unfounded stops: www.statnews.com/2025/10/06/g...
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com
Reposted
biorxiv-immuno.bsky.social
Impaired IFNγ responsiveness of lung monocyte-derived cells limits immunity to Mycobacterium tuberculosis https://www.biorxiv.org/content/10.1101/2025.10.06.680719v1
Reposted
nature.com
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize
A photo of a Nobel medal
sarasuliman.bsky.social
I had a feeling this was starting to happen.
jeremymberg.bsky.social
PubMed Update (no pun intended)

Publications with Pub Date

8/1//24 62209
9/1/24 64765
10/1/24 68211

8/1/25 61610
9/1/25 63719

10/1/25 35936 (as of 10/2/25)
10/1/25 38673 (as of 10/6/25, 8:00 AM)

It appears that ~40% of the expected number of publications are missing for 10/1/25

1/2
a man in a black vest says no bueno in front of mountains
ALT: a man in a black vest says no bueno in front of mountains
media.tenor.com
sarasuliman.bsky.social
This is very serious! Our job as scientists is to protect the truth we know it based on evidence. Whistle blower protection is so fundamental to achieving that. While pubmed is "down", I'm wondering if papers on vaccines are magically disappearing.

Jeanne Marrazzo is a national treasure!
Reposted
biorxiv-microbiol.bsky.social
Virally encoded interleukin-6 (vIL-6) coordinates with human IL-6 to modulate cytokine expression during KSHV infection https://www.biorxiv.org/content/10.1101/2025.10.02.679950v1
Reposted
phillewis.bsky.social
Jane Goodall, ethologist and conservationist, has died. She was 91
Reposted
sciencevs.bsky.social
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...
Reposted
jem.org
Kaiwen Zhu, Yan Lu, André Veillette et al. @ircm.bsky.social show that CD2 & its ligands regulate #MAITcell development and antigen responses by enhancing TCR signaling. A natural subset of human MAIT cells lacking CD2 exhibits reduced activation responses to antigen. rupress.org/jem/article/...
Reposted
gpollara.bsky.social
Good title this:

"Tuberculosis and the perils of historical amnesia"

Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.."

#TBSky #IDSky @lancetmicrobe.bsky.social
Tuberculosis and the perils of historical amnesia
In a recent Comment published in The Lancet, Hans Henri P Kluge emphasised the urgency of addressing drug-resistant tuberculosis in the WHO European region.1 Although the health security framing…
www.thelancet.com
Reposted
jem.org
Type I IFN drives #neutrophil swarming, impeding lung T cell–#macrophage interactions and #TB control, say William Branchett, Anne O’Garra et al. @crick.ac.uk rupress.org/jem/article/...

#Tuberculosis
Reposted
sfmpathogenesis.bsky.social
New study shows pyrazinamide kills TB by acidifying bacterial cytosol — not via PanD/CoA depletion. A long-standing debate settled, paving the way for smarter PZA-like drugs. #MicroSky

✍️ J. Laudouze, Y. Antonenko, @alexandregouzy.bsky.social, @pierresantucci.bsky.social & coll.
📖 shorturl.at/tuz6Q
Revisited model of PZA/HPOA efficacy, supporting a pH-dependent mechanism of weak acid permeation and cytosolic acidification as main mechanism of bactericidal activity. In this model, the authors propose that the presence of glycerol potentiates PZA/HPOA efficacy by generating acidic intermediates that lower IBpH. Accordingly, β-alanine and pantothenate might mitigate this effect by acting as buffering molecules that alleviate acidosis. Finally, PanD enzymatic activity consumes protons which in turn increases IBpH. Therefore, in this model PanD minimally contributes to PZA tolerance and cannot be considered as the primary target of the drug.
sarasuliman.bsky.social
Timeline cleanse 🎻❤️
demolatheviollnist.bsky.social
Yes 1 👀 it lol. #flashbackfriday 🎶 : Careless Whisper - @George Michael #80smusic #wham #demolaviolinist #georgemichael #demola #carelesswhisper