Tanveer Batth
@tsbatth.bsky.social
Co-founder/CEO KPL ApS , #Proteomics researcher in Copenhagen, Denmark at Københavns Universitet, NNF Center for Protein Research #science, #technology, #culture, memes and vibes.
Pinned
Tanveer Batth
@tsbatth.bsky.social
· Nov 10
Ok, going to try to repost the thread on here as well :)
---------
I'm happy to report the publication of our latest #proteomics paper has been published in Nature Communications
. Thanks to the reviewers and editors who helped us improve the manuscript!
rdcu.be/dZLbk
A small 🧵below
---------
I'm happy to report the publication of our latest #proteomics paper has been published in Nature Communications
. Thanks to the reviewers and editors who helped us improve the manuscript!
rdcu.be/dZLbk
A small 🧵below
Our latest #proteomics product to top off our Lys-C and Trypsin offerings. A high quality optimal premix of Lys-C and Trypsin that enables reproducible proteomic analysis! Make sure to follow @kplaps.bsky.social for more exciting news and updates!
#TeamMassSpec
#TeamMassSpec
🧪 Just launched: Trypsin/Lys-C Premium Mix 🚀
We found that with the right formulation, you can add Lys-C and Trypsin together instead of sequentially. So we made it 💡
✅ One step
✅ Lowest missed cleavages in its class
✅ Fully recombinant
🪧Available now
🔗 kplbio.com/trypsinlysc/
We found that with the right formulation, you can add Lys-C and Trypsin together instead of sequentially. So we made it 💡
✅ One step
✅ Lowest missed cleavages in its class
✅ Fully recombinant
🪧Available now
🔗 kplbio.com/trypsinlysc/
February 17, 2026 at 2:07 PM
Our latest #proteomics product to top off our Lys-C and Trypsin offerings. A high quality optimal premix of Lys-C and Trypsin that enables reproducible proteomic analysis! Make sure to follow @kplaps.bsky.social for more exciting news and updates!
#TeamMassSpec
#TeamMassSpec
Reposted by Tanveer Batth
Check out the first author!
pubmed.ncbi.nlm.nih.gov/30671891/
pubmed.ncbi.nlm.nih.gov/30671891/
Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows - PubMed
A major goal of proteomics research is the accurate and sensitive identification and quantification of a broad range of proteins within a sample. Data-independent acquisition (DIA) approaches that acquire MS/MS spectra independently of precursor information have been developed to overcome the reprod …
pubmed.ncbi.nlm.nih.gov
February 17, 2026 at 2:14 AM
Check out the first author!
pubmed.ncbi.nlm.nih.gov/30671891/
pubmed.ncbi.nlm.nih.gov/30671891/
Reposted by Tanveer Batth
Looks like proteomics has hit the big time!
February 17, 2026 at 2:06 AM
Looks like proteomics has hit the big time!
Reposted by Tanveer Batth
Ooooh. Cool new paper on origins of life. A simple 45-nucleotide RNA molecule that can perfectly copy itself.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
www.science.org
February 13, 2026 at 2:19 AM
Ooooh. Cool new paper on origins of life. A simple 45-nucleotide RNA molecule that can perfectly copy itself.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Tanveer Batth
By 2028, all 4-character PDB IDs will be exhausted.
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
February 12, 2026 at 11:32 AM
By 2028, all 4-character PDB IDs will be exhausted.
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)
Test it from PDB Beta Archive
Read more: www.wwpdb.org/news/news?ye...
Reposted by Tanveer Batth
1/ The Dolphin Head (Sh2-308) is an emission nebula in the Canis Major region: a huge bubble created by material expelled by the star WR6, swept by its powerful stellar wind.
It’s also a target that drove me crazy for four years before I finally started to get a grip on it. ➡️
🔭
#Astrophotography
It’s also a target that drove me crazy for four years before I finally started to get a grip on it. ➡️
🔭
#Astrophotography
February 11, 2026 at 2:41 PM
1/ The Dolphin Head (Sh2-308) is an emission nebula in the Canis Major region: a huge bubble created by material expelled by the star WR6, swept by its powerful stellar wind.
It’s also a target that drove me crazy for four years before I finally started to get a grip on it. ➡️
🔭
#Astrophotography
It’s also a target that drove me crazy for four years before I finally started to get a grip on it. ➡️
🔭
#Astrophotography
Reposted by Tanveer Batth
close enough?! (home made needle columns)
February 10, 2026 at 4:28 PM
close enough?! (home made needle columns)
Me every single time i need to prepare a LCMS setup to run a couple of samples ...
#proteomics
#proteomics
February 10, 2026 at 8:21 PM
Me every single time i need to prepare a LCMS setup to run a couple of samples ...
#proteomics
#proteomics
Reposted by Tanveer Batth
Aside from the whisper network, how are #teammassspec finding out how much certain instrument models are down for (service delays, backordered parts, things breaking all the time, etc)?
February 3, 2026 at 8:46 AM
Aside from the whisper network, how are #teammassspec finding out how much certain instrument models are down for (service delays, backordered parts, things breaking all the time, etc)?
Reposted by Tanveer Batth
BPC-157 hasn't been approved by the FDA. But that hasn't stopped this buzzy drug from gaining traction – and attention from MAHA. www.statnews.com/2026/02/03/b...
From Croatia to MAHA: How an unapproved drug became the next hot peptide
BPC-157 hasn't been approved by the FDA. But that hasn't stopped this buzzy drug from gaining traction – and attention from MAHA.
www.statnews.com
February 3, 2026 at 4:57 PM
BPC-157 hasn't been approved by the FDA. But that hasn't stopped this buzzy drug from gaining traction – and attention from MAHA. www.statnews.com/2026/02/03/b...
Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality, high performance, drop in replacement for any existing #proteomics workflows.
Designed and produced in 🇩🇰🇪🇺
Designed and produced in 🇩🇰🇪🇺
Introducing Trypsin RMS – our third product is here.
Recombinant. Methylated. Sequencing-grade.
The robust trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: kplbio.com/trypsin/
#TeamMassSpec #science #proteins #enzymes
Recombinant. Methylated. Sequencing-grade.
The robust trypsin #proteomics labs need, without the batch variability of animal-derived alternatives.
Learn more: kplbio.com/trypsin/
#TeamMassSpec #science #proteins #enzymes
February 2, 2026 at 8:34 AM
Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality, high performance, drop in replacement for any existing #proteomics workflows.
Designed and produced in 🇩🇰🇪🇺
Designed and produced in 🇩🇰🇪🇺
Reposted by Tanveer Batth
Zotero 8 is out, and we are very lucky to have such great open source software
January 27, 2026 at 3:45 AM
Zotero 8 is out, and we are very lucky to have such great open source software
Reposted by Tanveer Batth
Pervanadate is more than just a phosphatase inhibitor!
Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.
Link: tinyurl.com/5ype7e2s
Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3
@babrahaminst.bsky.social
Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.
Link: tinyurl.com/5ype7e2s
Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3
@babrahaminst.bsky.social
Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC
A widely used tyrosine phosphatase inhibitor also oxidizes and activates the tyrosine kinase SRC.
www.science.org
January 21, 2026 at 8:35 AM
Pervanadate is more than just a phosphatase inhibitor!
Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.
Link: tinyurl.com/5ype7e2s
Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3
@babrahaminst.bsky.social
Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.
Link: tinyurl.com/5ype7e2s
Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3
@babrahaminst.bsky.social
Reposted by Tanveer Batth
Single-cell proteomics is moving past descriptive snapshots to quantitative models of cellular regulation and biological mechanisms.
Come to #Boston this July to shape the next chapter and have your voice heard.
Abstract deadline: Apr 1, 2026.
single-cell.net/proteomics/s...
Come to #Boston this July to shape the next chapter and have your voice heard.
Abstract deadline: Apr 1, 2026.
single-cell.net/proteomics/s...
January 20, 2026 at 1:48 PM
Single-cell proteomics is moving past descriptive snapshots to quantitative models of cellular regulation and biological mechanisms.
Come to #Boston this July to shape the next chapter and have your voice heard.
Abstract deadline: Apr 1, 2026.
single-cell.net/proteomics/s...
Come to #Boston this July to shape the next chapter and have your voice heard.
Abstract deadline: Apr 1, 2026.
single-cell.net/proteomics/s...
Reposted by Tanveer Batth
Trypsin is the workhorse of bottom-up #proteomics. But when was it first discovered? Lets try an emoji poll !
😇 1836
🤭 1876
😜 1897
🤑 1931
Reply with your guess!
Correct answer in the replies!
#TeamMassSpec
😇 1836
🤭 1876
😜 1897
🤑 1931
Reply with your guess!
Correct answer in the replies!
#TeamMassSpec
January 15, 2026 at 11:05 PM
Trypsin is the workhorse of bottom-up #proteomics. But when was it first discovered? Lets try an emoji poll !
😇 1836
🤭 1876
😜 1897
🤑 1931
Reply with your guess!
Correct answer in the replies!
#TeamMassSpec
😇 1836
🤭 1876
😜 1897
🤑 1931
Reply with your guess!
Correct answer in the replies!
#TeamMassSpec
New publication alert! 📢
We collaborated with @jesperolsenlab.bsky.social to comprehensively characterize LysC homologs and study their impact on proteomic experiments.
For challenging samples, adding LysC can definitely make a difference in the data quality.
Congrats to all authors!
#proteomics
We collaborated with @jesperolsenlab.bsky.social to comprehensively characterize LysC homologs and study their impact on proteomic experiments.
For challenging samples, adding LysC can definitely make a difference in the data quality.
Congrats to all authors!
#proteomics
Does enzyme quality matter in #proteomics?
New study in JPR w/ @jesperolsenlab.bsky.social shows: LysC-Trypsin reduces missed cleavages from 30% → 15%
KPL's A. lyticus LysC achieves >90% efficiency in systematic comparison.
Congrats to the authors!
pubs.acs.org/doi/10.1021/...
#TeamMassSpec
New study in JPR w/ @jesperolsenlab.bsky.social shows: LysC-Trypsin reduces missed cleavages from 30% → 15%
KPL's A. lyticus LysC achieves >90% efficiency in systematic comparison.
Congrats to the authors!
pubs.acs.org/doi/10.1021/...
#TeamMassSpec
Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows
This study presents a comparative analysis of three LysC endopeptidase homologues from Achromobacter lyticus (A. lyticus),Pseudomonas aeruginosa and Lysobacter enzymogenes for mass spectrometry-based proteomics. Utilizing a protein aggregation capture workflow with HeLa cell lysates, we assessed the enzymes’ cleavage specificity, digestion efficiency, and performance across various experimental conditions. Results showed that while all three LysC homologues exhibited high cleavage specificity at lysine residues, A. lyticus LysC outperformed the two others with superior peptide identification, digestion efficiency, and protein coverage, especially at shorter digestion times. Our experiments using a combination ofA. lyticusLysC and trypsin demonstrated the importance of employing LysC for significantly minimizing missed cleavage rates in tryptic digests, especially with regard to lysine-containing peptides. This study underscores A. lyticus LysC’s potential as an optimal choice for enhancing mass spectrometry-based proteomics.
pubs.acs.org
January 13, 2026 at 11:39 AM
New publication alert! 📢
We collaborated with @jesperolsenlab.bsky.social to comprehensively characterize LysC homologs and study their impact on proteomic experiments.
For challenging samples, adding LysC can definitely make a difference in the data quality.
Congrats to all authors!
#proteomics
We collaborated with @jesperolsenlab.bsky.social to comprehensively characterize LysC homologs and study their impact on proteomic experiments.
For challenging samples, adding LysC can definitely make a difference in the data quality.
Congrats to all authors!
#proteomics
Reposted by Tanveer Batth
AutoPELSA: an automated sample preparation system for proteome-wide identification of target proteins of diverse ligands https://www.biorxiv.org/content/10.64898/2026.01.08.697612v1
January 9, 2026 at 8:16 PM
AutoPELSA: an automated sample preparation system for proteome-wide identification of target proteins of diverse ligands https://www.biorxiv.org/content/10.64898/2026.01.08.697612v1
To everyone who's supported us, bought from us, or just followed along to see what happens ... Thank you for a great year, you're the real MVPs!
2026 pipeline is looking spicy 🌶️ new products, big announcements I believe will push the field of #proteomics forward. Stay tuned.
2026 pipeline is looking spicy 🌶️ new products, big announcements I believe will push the field of #proteomics forward. Stay tuned.
Happy Holidays from KPL! 🎄
Our first full year: 2 product launches, lots of foundation building, and countless hours pushing #proteomics forward.
Our commitment: high quality, high performance, competitive prices. No compromises.
2026 is looking exciting - stay tuned! ✨
Our first full year: 2 product launches, lots of foundation building, and countless hours pushing #proteomics forward.
Our commitment: high quality, high performance, competitive prices. No compromises.
2026 is looking exciting - stay tuned! ✨
December 26, 2025 at 9:37 PM
To everyone who's supported us, bought from us, or just followed along to see what happens ... Thank you for a great year, you're the real MVPs!
2026 pipeline is looking spicy 🌶️ new products, big announcements I believe will push the field of #proteomics forward. Stay tuned.
2026 pipeline is looking spicy 🌶️ new products, big announcements I believe will push the field of #proteomics forward. Stay tuned.
Really curious to get peoples experience with using SCIEX instruments for bottom up proteomics 🤔🤔 Remember you can post anonymously so please share the price as well ! 😅
Take a break from holiday doom scrolling and help somebody decide on which MS instrument to purchase for #proteomics! Specifically, one user is requesting input to decide between SCIEX or Thermo for proteomic MS instrument.
old.reddit.com/r/proteomics...
#Teammassspec
old.reddit.com/r/proteomics...
#Teammassspec
SCIEX or Thermo for Proteomics
Posted in r/proteomics by u/Expensive-Painter-18 • 4 points and 1 comment
old.reddit.com
December 26, 2025 at 6:10 PM
Really curious to get peoples experience with using SCIEX instruments for bottom up proteomics 🤔🤔 Remember you can post anonymously so please share the price as well ! 😅
Reposted by Tanveer Batth
Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows pubs.acs.org/doi/10....
---
#proteomics #prot-paper
---
#proteomics #prot-paper
December 23, 2025 at 2:20 PM
Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows pubs.acs.org/doi/10....
---
#proteomics #prot-paper
---
#proteomics #prot-paper
Reposted by Tanveer Batth
When viewing the fake article in Google scholar on my university network, there is a link to access the article via my uni's library. That link sends me to a library page that makes fake article appear real... Turns out library page is made programmatically from info on Google scholar 🤦
December 21, 2025 at 1:48 AM
When viewing the fake article in Google scholar on my university network, there is a link to access the article via my uni's library. That link sends me to a library page that makes fake article appear real... Turns out library page is made programmatically from info on Google scholar 🤦
Reposted by Tanveer Batth
Reposted by Tanveer Batth
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Reposted by Tanveer Batth
Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
December 12, 2025 at 3:53 PM
Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
Reposted by Tanveer Batth
#AminoAcidAdvent Day 5: Threonine (Thr; T)
This essential amino acid was the last of "the 20" discovered, with no relation to the number 3 (sorry Jack White), but 1 of our 3 phosphomusketeers (TM). Dayhoff gave it the honors of T cause it was more frequent than the other T's... take that Y and W!
This essential amino acid was the last of "the 20" discovered, with no relation to the number 3 (sorry Jack White), but 1 of our 3 phosphomusketeers (TM). Dayhoff gave it the honors of T cause it was more frequent than the other T's... take that Y and W!
December 8, 2025 at 1:09 PM
#AminoAcidAdvent Day 5: Threonine (Thr; T)
This essential amino acid was the last of "the 20" discovered, with no relation to the number 3 (sorry Jack White), but 1 of our 3 phosphomusketeers (TM). Dayhoff gave it the honors of T cause it was more frequent than the other T's... take that Y and W!
This essential amino acid was the last of "the 20" discovered, with no relation to the number 3 (sorry Jack White), but 1 of our 3 phosphomusketeers (TM). Dayhoff gave it the honors of T cause it was more frequent than the other T's... take that Y and W!