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altmeyerlab @altmeyerlab.bsky.social · 6d

A comprehensive genetic catalog of human double-strand break repair | Science www.science.org/doi/10.1126/...

A comprehensive genetic catalog of human double-strand break repair

The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

www.science.org

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Katharine Hayhoe @katharinehayhoe.com · 7d

The world has lost its most powerful advocate for nature and hope. Yet many remain who will continue her legacy and I know she will continue to inspire generations more.

A screenshot of a post by the Jane Goodall Institute on LinkedIn stating that they learned that Dr. Goodall passed away due to natural causes in California while on her speaking to her current speaking tour there.

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Mcclelland lab @mcclellandlab.bsky.social · 7d

Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.

Professors x 10, Faculty of Medicine & Dentistry | Veredus

QUEEN MARY UNIVERSITY OF LONDON Professors x 10, Faculty of Medicine and Dentistry London Competitive Remuneration Package Queen Mary University of London seeks up to 10 world-leading translational re...

www.veredus.co.uk

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Hopfner Lab @hopfnerlab.bsky.social · 20d

Thrilled that our work is now finally out in Nature Comms!
rdcu.be/eG3vP

We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres.
Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!

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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 27d

Congratulations to Dirk Görlich and Steven L. McKnight, 2025 #LaskerAward winners! - “for discoveries that exposed the structures and functions of low-complexity domains within protein sequences” 🧪
@mpi-nat.bsky.social
#Lasker2025 #LaskerLaureate #structuralbiology #phaseseparation

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Uli Rass @u-rass.bsky.social · Sep 3

My first post on bsky to share our latest research in @nature.com: “DNA2 enables growth by restricting recombination-restarted replication” - defines DNA2’s essential function & elucidates links with primordial dwarfism and cancer. Thanks to the lab, collaborators & @ukri.org @acmedsci.bsky.social

DNA2 enables growth by restricting recombination-restarted replication - Nature

DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and cell-cycle exit, high...

www.nature.com

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Fusion Conferences @fusionconf.bsky.social · Sep 2

📢Deadline extended!
Our 2nd Spatial Genome Organisation Conference deadline has been extended to 25 Sep, dont miss out on joining our fantastic line up of speakers, alongside Karim, Matthias and Irene in what is set to be a fantastic meeting this October! #SGO25
Final slots ➡️https://bit.ly/3JJzYR4

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Fusion Conferences @fusionconf.bsky.social · Sep 2

@efapostolou29.bsky.social @thecesarelab.bsky.social we're looking forward to your presentations at this fantastic meeting!

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Daniel Durocher @durocher1.bsky.social · Aug 28

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

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Fusion Conferences @fusionconf.bsky.social · Aug 27

Deadline approaching for #SGO25

🗓 31 Oct – 03 Nov 2025
📍Riviera Maya, Mexico

Poster & Reg deadline: 01 Sept 2025
Details & Reg: bit.ly/45Mmhtv

$250 registration grants available! Email [email protected] with your name, position & current research topic.

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David Cortez @dkcortez.bsky.social · Aug 14

Advertisements for 2 tenure-track assistant professor positions at Vanderbilt School of Medicine Basic Sciences:
www.nature.com/naturecareer...
www.nature.com/naturecareer...

Assistant Professor of Biochemistry at Vanderbilt University - Nashville, Tennessee job with Vanderbilt University School of Medicine | 12843515

Department of Biochemistry, School of Medicine—Basic Sciences

www.nature.com

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Replifate Consortium @replifate.bsky.social · Aug 11

Another exciting research article from a member of the #RepliFate network!

The Altmeyer lab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis.

Check out their findings here: doi.org/10.1016/j.ce...

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altmeyerlab @altmeyerlab.bsky.social · Jul 31

New work from the lab: Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling @cp-cellreports.bsky.social. Congratulations to first author Antonio Galarreta and to all co-authors. www.cell.com/cell-reports.... #Microscopy #RNAiScreen #Condensates

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Ellenberg Lab @ellenberglab.bsky.social · Jul 21

Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out!

www.nature.com/articles/s41...

Congratulations to Kai and Oyvind!!

Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications

A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...

www.nature.com

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IGMM-Montpellier @igmm-montpel.bsky.social · May 28

📣 We are recruiting new group leaders in Innovative Biology!

RNA biology
Epigenetic regulation
Cell cycle regulation
Cancer, immunology
Virology

Application and information ⬇️
application.igmm.cnrs.fr

@cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social

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Eric Topol @erictopol.bsky.social · May 21

New @nature.com
An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer
www.nature.com/articles/s41...

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Sarah Aitken @s-j-aitken.bsky.social · May 21

🔬Under the microscope: DNA damage tracked through cell generations🔬

It was a pleasure to write this #NewsAndViews with our PhD student Emma Reilly, online today @nature.com

rdcu.be/em0qi

@cruk-ci.bsky.social @spjacksongroup.bsky.social @yalepathology.bsky.social @yalecancer.bsky.social

Under the microscope: DNA damage tracked through cell generations | Nature

An ingenious technique reveals how stressed cells divide to produce progeny that have different traits — a phenomenon that can initiate cancer. An ingenious technique reveals how stressed cells divide to produce progeny that have different traits — a phenomenon that can initiate cancer.

rdcu.be

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altmeyerlab @altmeyerlab.bsky.social · May 21

Sharing our latest work tracking DNA damage inheritance by Live+QIBC www.nature.com/articles/s41.... Huge congrats to @apanagopoulos.bsky.social, M. Stout and all co-authors for this tour de force! Beautifully summarized by @s-j-aitken.bsky.social & E. Reilly www.nature.com/articles/d41...

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altmeyerlab @altmeyerlab.bsky.social · May 15

Looking very much forward to the 2nd edition of the Fusion Conference on Spatial Genome Organisation #SGO25 @fusionconf.bsky.social @karimmekhail.bsky.social @chiololab.bsky.social. Early bird registration closes soon: June 2nd, 2025. Slots available for selected talks from abstracts: bit.ly/4492G6i

2nd Spatial Genome Organisation Conference | Fusion Conferences

Our scientific research conferences support the development of physical, medical and life sciences, providing a powerful platform that encourages discussion and collaboration in luxury locations acros...

www.fusion-conferences.com

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Institute of Molecular Biotechnology @imbavienna.bsky.social · May 14

IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply by May 18: imba.science/beagroupleader #hiring #biology #research #groupleader #europe

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DGZ.bsky.social @dgz.bsky.social · Apr 8

We are excited to announce the details for this year’s #DGZ International Meeting, a very special one as we are celebrating 50 years of DGZ! Join us in October in Heidelberg, where the DGZ was founded in 1975. Check the speakers line-up etc. at the poster. Registration: shorturl.at/EHUzb #DGZ50

Poster with DGZ 2025 Meeting details (speakers list, organizers, sponsors)

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Laboratory of Genomic Stability @lgs-imb.bsky.social · Apr 7

We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology.
www.nature.com/articles/s41...

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altmeyerlab @altmeyerlab.bsky.social · Mar 27

Interested in these or related topics and looking for (or know somebody looking for) a PhD position? We have openings and an approaching application deadline @lifesciencezurich.bsky.social: www.lifescience-graduateschool.uzh.ch/en.html. Please repost. #PhDLife #LifeScience #Switzerland

altmeyerlab @altmeyerlab.bsky.social · Mar 18

How are chromosome breaks repaired and how is their repair influenced and facilitated by nuclear and genome dynamics? Fantastic initiative and collaboration with @karimmekhail.bsky.social, @chiololab.bsky.social, and @lablegube.bsky.social. @natrevmcb.bsky.social Link to article: rdcu.be/edViW

Nuclear and genome dynamics underlying DNA double-strand break repair

Nature Reviews Molecular Cell Biology - Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the...

rdcu.be

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zhoujt.bsky.social @zhoujt.bsky.social · Mar 25

1/10 Excited to share our latest - the first whole-body map of both DNA methylation and 3D genome at single-cell resolution.

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Ellenberg Lab @ellenberglab.bsky.social · Mar 24

Our new findings on how chromosomes get ready for cell division are now published in @cellpress.bsky.social!

Congratulations, Kai, @andibrunner.bsky.social and everyone else involved! 🤩

www.sciencedirect.com/science/arti...

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