Mcclelland lab
@mcclellandlab.bsky.social
1.8K followers
540 following
51 posts
Investigating origins and vulnerabilities of cancer chromosomal instability at the Barts Cancer Institute, London UK. Www.Mcclellandlab.com
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Mathew Jones
@jonesmjk.bsky.social
· Sep 1
A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells
Nature Communications - Determining how replication forks move across the human genome is critical for the effective use of agents that target replication stress. Here, the authors present...
rdcu.be
Reposted by Mcclelland lab
Reposted by Mcclelland lab
Reposted by Mcclelland lab
Uli Rass
@u-rass.bsky.social
· Sep 3
DNA2 enables growth by restricting recombination-restarted replication - Nature
DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and cell-cycle exit, high...
www.nature.com
Reposted by Mcclelland lab
Reposted by Mcclelland lab