Bart Larsen
@bart-larsen.bsky.social
Assistant Professor at University of Minnesota
Masonic Institute for the Developing Brain
Developmental neuroscience, neuroimaging, modeling 📈🧠
Masonic Institute for the Developing Brain
Developmental neuroscience, neuroimaging, modeling 📈🧠
Reposted by Bart Larsen
Excited to share our new review “Mapping interactions between adversity and neuroplasticity across development” in @cp-trendscognsci.bsky.social. We discuss how experience - particularly adversity - interacts with neuroplasticity during human development authors.elsevier.com/c/1mB5U4sIRv...
December 1, 2025 at 4:58 PM
Excited to share our new review “Mapping interactions between adversity and neuroplasticity across development” in @cp-trendscognsci.bsky.social. We discuss how experience - particularly adversity - interacts with neuroplasticity during human development authors.elsevier.com/c/1mB5U4sIRv...
Reposted by Bart Larsen
Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology.
pbs.jhu.edu/about/jobs/
pbs.jhu.edu/about/jobs/
Jobs | Psychological & Brain Sciences
Tenured/Tenure-track position in Cognitive Psychology Open Date Dec 01, 2025 Salary Range or Pay Grade The expected academic base salary range for this position is $110,000- $144,500 (Assistant Profes...
pbs.jhu.edu
December 2, 2025 at 12:00 AM
Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology.
pbs.jhu.edu/about/jobs/
pbs.jhu.edu/about/jobs/
Reposted by Bart Larsen
Is the “standard workflow” holding back fMRI analysis?
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
November 18, 2025 at 10:13 PM
Is the “standard workflow” holding back fMRI analysis?
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
Mass-univariate analysis is still the bread-and-butter: intuitive, fast… and chronically overfitted. Add harsh multiple-comparison penalties, and we patch the workflow with statistical band-aids. No wonder the stringency debates never die.
I can't recommend this fantastic new review from @valeriejsydnor.bsky.social enough! It does an amazing job of synthesizing the current state of the literature and then looking forward to provide a fresh perspective on how to move this work forward in humans. Check it out!
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
November 12, 2025 at 4:58 PM
I can't recommend this fantastic new review from @valeriejsydnor.bsky.social enough! It does an amazing job of synthesizing the current state of the literature and then looking forward to provide a fresh perspective on how to move this work forward in humans. Check it out!
Reposted by Bart Larsen
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications
The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...
www.biorxiv.org
November 11, 2025 at 10:03 PM
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
Reposted by Bart Larsen
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN.
It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package.
Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package.
Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
ggplot2 4.0.0
A new major version of ggplot2 has been released on CRAN. Find out what is new here.
www.tidyverse.org
September 11, 2025 at 11:20 AM
Reposted by Bart Larsen
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
This paper truly exemplifies what is possible in the modern era of neuroimaging data. A beautiful and extremely impressive piece of work from @valeriejsydnor.bsky.social that was a treat to contribute to. Check it out!
How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...
July 9, 2025 at 2:45 PM
This paper truly exemplifies what is possible in the modern era of neuroimaging data. A beautiful and extremely impressive piece of work from @valeriejsydnor.bsky.social that was a treat to contribute to. Check it out!
Reposted by Bart Larsen
OK, It is not just the HBCD release...
docs.hbcdstudy.org
It’s the ABCD Release time too!
docs.abcdstudy.org
nbdc-datahub.org
That means the ABCC 3.0.0 is live!!!
The largest release yet from the ABCD-BIDS Community Collection.
This is going to be fun!!
👇 Let’s dig in.
docs.hbcdstudy.org
It’s the ABCD Release time too!
docs.abcdstudy.org
nbdc-datahub.org
That means the ABCC 3.0.0 is live!!!
The largest release yet from the ABCD-BIDS Community Collection.
This is going to be fun!!
👇 Let’s dig in.
Alert! ... for the child development world!
@fluxsociety.bsky.social @fitngin.bsky.social
The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive.
Check here:
docs.hbcdstudy.org
and here:
nbdc-datahub.org
Here’s why it matters 🧠🍼
@fluxsociety.bsky.social @fitngin.bsky.social
The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive.
Check here:
docs.hbcdstudy.org
and here:
nbdc-datahub.org
Here’s why it matters 🧠🍼
June 29, 2025 at 4:39 PM
OK, It is not just the HBCD release...
docs.hbcdstudy.org
It’s the ABCD Release time too!
docs.abcdstudy.org
nbdc-datahub.org
That means the ABCC 3.0.0 is live!!!
The largest release yet from the ABCD-BIDS Community Collection.
This is going to be fun!!
👇 Let’s dig in.
docs.hbcdstudy.org
It’s the ABCD Release time too!
docs.abcdstudy.org
nbdc-datahub.org
That means the ABCC 3.0.0 is live!!!
The largest release yet from the ABCD-BIDS Community Collection.
This is going to be fun!!
👇 Let’s dig in.
Reposted by Bart Larsen
Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠
#neuroskyence #neuroimaging #psychscisky
#neuroskyence #neuroimaging #psychscisky
✨New Preprint!✨ Sex differences in psychiatric disorders often show up in adolescence as disparities in prevalence, symptoms, and treatment outcomes. We aimed to understand sex diffs in brain organization that might lead to these disparities!
t.ly/x6oxC
🧵⬇️
#neuroskyence #psychscisky #Neuroimaging
t.ly/x6oxC
🧵⬇️
#neuroskyence #psychscisky #Neuroimaging
Reproducible Sex Differences in Personalized Functional Network Topography in Youth
Background A key step towards understanding psychiatric disorders that disproportionately impact female mental health is delineating the emergence of sex-specific patterns of brain organization at the...
t.ly
April 22, 2025 at 8:13 PM
Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠
#neuroskyence #neuroimaging #psychscisky
#neuroskyence #neuroimaging #psychscisky
Reposted by Bart Larsen
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
April 11, 2025 at 1:35 AM
While the world burns, we cook up a new preprint! doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
Awesome opening salvo from the lab of @lindenmp.bsky.social!! Super cool work that will stem many future directions!
Excited to share the first major piece of work and preprint from my lab! Led by Jason Kim! 🥳🎉🤘
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
a man applauds with the words so proud of my team above him
ALT: a man applauds with the words so proud of my team above him
media.tenor.com
April 29, 2025 at 3:53 PM
Awesome opening salvo from the lab of @lindenmp.bsky.social!! Super cool work that will stem many future directions!
Reposted by Bart Larsen
Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇
#interoception 🧠🫀 #neuroskyence
elifesciences.org/reviewed-pre...
#interoception 🧠🫀 #neuroskyence
elifesciences.org/reviewed-pre...
Age-related changes in “cortical” 1/f dynamics are linked to cardiac activity
elifesciences.org
April 1, 2025 at 8:10 PM
Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇
#interoception 🧠🫀 #neuroskyence
elifesciences.org/reviewed-pre...
#interoception 🧠🫀 #neuroskyence
elifesciences.org/reviewed-pre...
Reposted by Bart Larsen
Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back.
This was the largest political gathering in Denver since Obama in 2008.
Also bigger than the 2024 DNC.
And the largest ever rally in Bernie’s career (and obviously, mine too).
This was the largest political gathering in Denver since Obama in 2008.
Also bigger than the 2024 DNC.
And the largest ever rally in Bernie’s career (and obviously, mine too).
March 22, 2025 at 1:29 AM
Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back.
This was the largest political gathering in Denver since Obama in 2008.
Also bigger than the 2024 DNC.
And the largest ever rally in Bernie’s career (and obviously, mine too).
This was the largest political gathering in Denver since Obama in 2008.
Also bigger than the 2024 DNC.
And the largest ever rally in Bernie’s career (and obviously, mine too).
Reposted by Bart Larsen
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n
1/n
March 20, 2025 at 5:14 PM
We think of white matter as the brain's highways—uniform conduits between cortices. But what if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development” www.biorxiv.org/content/10.1...
1/n
1/n
Reposted by Bart Larsen
Great analysis of the indirect cost rate announcement by @stuartbuck.bsky.social
Indirect Costs at NIH . . .
I wasn’t planning on spending part of a Saturday writing about cost accounting principles and the like, but NIH-world was hit with a doozy of a policy announcement on Friday night:
open.substack.com
February 8, 2025 at 11:44 PM
Great analysis of the indirect cost rate announcement by @stuartbuck.bsky.social
Reposted by Bart Larsen
For those who don't know, here are very real research costs that directs cannot cover - all fall within indirects: the buildings we work in (upkeep, maintenance, cleaning, etc), utilities, IT infrastructure, human resources, administrative staff, security, and lots more
The new NIH policy for indirect costs going forward is capped at 15%.
This is forever going to alter the science ecosystem, upending and destroying a number of programs at universities across the country.
grants.nih.gov/grants/guide...
This is forever going to alter the science ecosystem, upending and destroying a number of programs at universities across the country.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:03 AM
For those who don't know, here are very real research costs that directs cannot cover - all fall within indirects: the buildings we work in (upkeep, maintenance, cleaning, etc), utilities, IT infrastructure, human resources, administrative staff, security, and lots more
Reposted by Bart Larsen
Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠
New paper in Imaging Neuroscience by Julia Moser, Damien A. Fair, et al:
Multi-echo acquisition and thermal denoising advances precision functional imaging
direct.mit.edu/imag/article...
Multi-echo acquisition and thermal denoising advances precision functional imaging
direct.mit.edu/imag/article...
January 10, 2025 at 5:11 PM
Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠
Reposted by Bart Larsen
Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵
🔗 www.nature.com/articles/s44...
🧪🧵
An initiative for living evidence synthesis in clinical psychedelic research - Nature Mental Health
Renewed interest in psychedelics as treatments for mental disorders has recently emerged, but substantial challenges remain in obtaining evidence from available data to inform clinical decision-making...
www.nature.com
January 10, 2025 at 4:12 PM
Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵
🔗 www.nature.com/articles/s44...
🧪🧵
Reposted by Bart Larsen
hey -- i'm hiring a postdoc! the ad will be up shortly, but looking for someone with network neuroscience experience (very broadly). the position isn't tied to any specific project/grant, so lots of flexibility in terms of what you'd actually *do*. hmu if you might be interested/want to learn more!
December 3, 2024 at 3:39 PM
hey -- i'm hiring a postdoc! the ad will be up shortly, but looking for someone with network neuroscience experience (very broadly). the position isn't tied to any specific project/grant, so lots of flexibility in terms of what you'd actually *do*. hmu if you might be interested/want to learn more!
Reposted by Bart Larsen
Thank you, Dr. Fair! It was really a rewarding experience for me to collaborate with your team from #MIDB! @drdamienfair.bsky.social @tervoclemmensb.bsky.social @bart-larsen.bsky.social Thank you for all your efforts and expertise you put into this work; they truly made this work better!
Congratulations @kaidikang.bsky.social et al on their paper in Nature.
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Study design features increase replicability in brain-wide association studies - Nature
Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association ...
www.nature.com
November 28, 2024 at 1:17 AM
Thank you, Dr. Fair! It was really a rewarding experience for me to collaborate with your team from #MIDB! @drdamienfair.bsky.social @tervoclemmensb.bsky.social @bart-larsen.bsky.social Thank you for all your efforts and expertise you put into this work; they truly made this work better!
Reposted by Bart Larsen
Congratulations @kaidikang.bsky.social et al on their paper in Nature.
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Study design features increase replicability in brain-wide association studies - Nature
Optimizing study design is critical for increasing standardized effect sizes and replicability, and the features that increase replicability in cross-sectional and longitudinal brain-wide association ...
www.nature.com
November 27, 2024 at 11:31 PM
Congratulations @kaidikang.bsky.social et al on their paper in Nature.
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Also proud of the team at #MIDB in the support! @tervoclemmensb.bsky.social @bart-larsen.bsky.social and more!
If you are interested in optimizing study designs, take a look, it's a great read!
www.nature.com/articles/s41...
Reposted by Bart Larsen
We're excited to release new versions of our BIDS-Apps for processing and analyzing #dmri data, QSIPrep and QSIRecon! Our team has been working hard to prepare these pipelines to process infant data and bring them in line with the @nipreps.bsky.social ecosystem. #neuroimaging #nipreps #bids 1/10
November 22, 2024 at 2:39 PM
We're excited to release new versions of our BIDS-Apps for processing and analyzing #dmri data, QSIPrep and QSIRecon! Our team has been working hard to prepare these pipelines to process infant data and bring them in line with the @nipreps.bsky.social ecosystem. #neuroimaging #nipreps #bids 1/10
Reposted by Bart Larsen
👏👏👏 @ariellekeller.bsky.social et al. with cyclical GAMs, multi-dataset replication, and study planning relevance!
☀️ New preprint! ☀️ Cognitive tests from 23,000+ participants in 4 datasets show cyclical fluctuations across the calendar year, including a small but replicable “summer slide” where youth show worst performance after school vacation. t.ly/OMzgl
#PsychSciSky #CogPsyc #CogDev #devpsy #CogSci
Thread /1
#PsychSciSky #CogPsyc #CogDev #devpsy #CogSci
Thread /1
November 21, 2024 at 10:19 PM
👏👏👏 @ariellekeller.bsky.social et al. with cyclical GAMs, multi-dataset replication, and study planning relevance!
Very happy with how this one turned out!
This started as a curiosity, that built into a side project, and eventually into a very cool paper!
This was also super fun to work on with @ariellekeller.bsky.social! Check out her thread below and the preprint here: osf.io/preprints/ps...
This started as a curiosity, that built into a side project, and eventually into a very cool paper!
This was also super fun to work on with @ariellekeller.bsky.social! Check out her thread below and the preprint here: osf.io/preprints/ps...
November 21, 2024 at 3:28 PM
Very happy with how this one turned out!
This started as a curiosity, that built into a side project, and eventually into a very cool paper!
This was also super fun to work on with @ariellekeller.bsky.social! Check out her thread below and the preprint here: osf.io/preprints/ps...
This started as a curiosity, that built into a side project, and eventually into a very cool paper!
This was also super fun to work on with @ariellekeller.bsky.social! Check out her thread below and the preprint here: osf.io/preprints/ps...