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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Sep 4

Proud to announce the publication of our new paper describing the design, chemical synthesis and testing of a novel class of Complement 3a Receptor (C3aR) agonists and antagonists derived from the TLQP-21 peptide

@pubs.acs.org Journal of Medicinal Chemistry

pubs.acs.org/doi/10.1021/...

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Jul 3

Remider!
Applications for the McEwen Career Development fellowship in Social Determinants of Health supported by the NIA-BSR High Priority Research Network animalsocialaging-network.org are now open!

apply here animalsocialaging-network.org/funding/fell...

Animal Models for the Social Dimensions of Health and Aging Research Network

animalsocialaging-network.org

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Reposted by Alessandro Bartolomucci Lab

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · Jun 15

📢Applications for the McEwen fellowship are now open!

We expect to award 1-3 fellowships (up to $6,000 each) to early-career scientists with a proposal within the broad scope of our research network’s interests.

Deadline: July 15

Apply here: www.animalsocialaging-network.org/funding/fell...

Fellowships | Animal Models for the Social Dimensions of Health and Aging Research Network

www.animalsocialaging-network.org

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Jun 12

Reminder - funding opportunity available trough the @animalsocaging.bsky.social

Pilot & Feasibility Awards
Application period - June 1 to June 30

B. McEwen Career Development Fellowship
Application period - June 15 to July 15

Small/Working Group Awards
Application period - July 1 to July 31

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · Jun 1

📢Applications are OPEN for our Pilot awards!

Individual or mentored projects available with up to $20,000 in total costs! Read the full RFA and apply at the link below!

www.animalsocialaging-network.org/funding/pilo...

@smacklab.bsky.social @bartolomuccilab.bsky.social @jennytung.bsky.social

A graphic describing the details related to applying for the Pilot awards of the Animal Models Social Aging network. Visit animalsocialaging-network.org for details.

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Reposted by Alessandro Bartolomucci Lab

Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · May 19

📣 @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!📣

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

Animal Models for the Social Dimensions of Health and Aging Research Network

www.animalsocialaging-network.org

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Jun 9

New Study alert: “Epigenetic biomarkers of mortality risk in mice under chronic social stress" @geroscience.bsky.social

lnkd.in/dqPGrQx4

Mathematical models identified epigenetic biomarkers of mortality risk and an association with blood glucose levels, informing on individual aging trajectories.

Epigenetic biomarkers of mortality risk in mice under chronic social… | Alessandro Bartolomucci

New Study: “Epigenetic biomarkers of mortality risk in mice under chronic social stress,” just published in GeroScience. https://lnkd.in/dqPGrQx4 Our study used a large cohort of mice (350+) exposed...

www.linkedin.com

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Reposted by Alessandro Bartolomucci Lab

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · Jun 1

📢Applications are OPEN for our Pilot awards!

Individual or mentored projects available with up to $20,000 in total costs! Read the full RFA and apply at the link below!

www.animalsocialaging-network.org/funding/pilo...

@smacklab.bsky.social @bartolomuccilab.bsky.social @jennytung.bsky.social

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Reposted by Alessandro Bartolomucci Lab

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · May 23

New Research Network publication alert!

@sheehanmj.bsky.social and @matthewzipple.bsky.social, both recipients of Network Pilot & Feasibility awards, have published a paper in Aging Cell on ecological realism and epigenetic aging in mice. Congratulations, Mike and Matthew! doi.org/10.1111/acel...

Ecological Realism Accelerates Epigenetic Aging in Mice

Living environment shapes mammalian aging, but laboratory conditions lack the ecological realism of natural social, physical, and microbial environments. Comparing traditionally laboratory-reared and...

doi.org

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · May 19

📣 @animalsocaging.bsky.social NIA-funded high priority research network - funding available soon!📣

Stay tuned for 3 RFAs:
1. Pilot awards - June 30th
2. The Bruce McEwen Fellowship - July 15
3. Small/working group - July 31

More info on the network: www.animalsocialaging-network.org

Animal Models for the Social Dimensions of Health and Aging Research Network

www.animalsocialaging-network.org

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Reposted by Alessandro Bartolomucci Lab

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · May 16

📣New network funding available soon!📣

The Request for Applications for our Research Network's pilot awards (June 1-June 30), the Bruce McEwen Fellowship (June 15-July 15), and small/working group awards (July 1-July 31) will be live on our website (www.animalsocialaging-network.org) in two weeks!

Animal Models for the Social Dimensions of Health and Aging Research Network

www.animalsocialaging-network.org

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · May 14

That`s a big one!
congrats to the outstanding team of co-authors

Anne Loft @anneloftsdu.bsky.social · May 14

Check out our new roadmap for single cell analyses of adipose tissue at @natmetabolism.nature.com 🧐 Thrilled to share our work put together by great colleagues from Adipose Bionetwork in @humancellatlas.org 🤩 Huge thanks to my fellow co-coordinators @smandrup.bsky.social Evan Rosen and Margo Emont

Nature Metabolism @natmetabolism.nature.com · May 13

Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · May 13

Our NIA funded High Priority Research network on Animal Models for the Social Dimension of Health and Aging just landed on Bsky @animalsocaging.bsky.social
- follow us for updates and new RFAs

www.animalsocialaging-network.org

@smacklab.bsky.social @jennytung.bsky.social

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Reposted by Alessandro Bartolomucci Lab

Animal Models for Social Dimensions of Health and Aging Network @animalsocaging.bsky.social · May 12

🎤Hey, is this thing on?

The Animal Models for the Social Dimensions of Health and Aging Research Network is on Bluesky! We are an NIA-funded network headquartered at UMN, ASU, UNC, and Duke that supports early-career scientists using animal models to study social aging. New funding available soon!

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · May 8

🚨 Great opportunity for an excellent post doc with a fantastic international group of top notch scholars.

Lauren Brent @ljnbrent.bsky.social · May 2

Postdoc job alert! I'm hiring a 3-yr postdoc to work on our Social Modifiers of Primate Lifespans grant. Job info and how to apply below. Deadline June 1. Pls share! jobs.exeter.ac.uk/hrpr_webrecr...

Powered by MHR

jobs.exeter.ac.uk

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Reposted by Alessandro Bartolomucci Lab

Björn Schumacher @bjornschumacher.bsky.social · Apr 30

Read here our original article showing the biological age prediction by accumulating stochastic variation alone. With @meyer.bsky.social and a wonderful cover art designed by @maayanvisuals.bsky.social www.nature.com/articles/s43...

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Apr 25

Post on the study by the first author @claudiagil93.bsky.social

bsky.app/profile/clau...

Cláudia Gil @claudiagil93.bsky.social · Mar 27

🌟 Exciting News! 🌟
I am thrilled to share that my first paper as the first author, Food insecurity promotes adiposity in mice, is now published in #ObesityJournal #ObesitySociety

doi.org/10.1002/oby....

#Foodinsecurity #Obesity #PhD

1/9🧵👇

Food insecurity promotes adiposity in mice

Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

doi.org

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Apr 25

Food insecurity drives obesity and adiposity, but how is unclear.
A recent study by @clemmensenc.bsky.social developed a mouse model for this phenomenon lnkd.in/d8pEp2qv
Happy to share a commentary written with @johnspeakman4.bsky.social with our take on that study
doi.org/10.1002/oby....

Scarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in mice

Click on the article title to read more.

doi.org

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Reposted by Alessandro Bartolomucci Lab

Proceedings of the National Academy of Sciences @pnas.org · Apr 7

The gap in life expectancy between the richest and poorest Swedes widened between 1960–2021. The cause of this trend was not increased inequality or a decline in social spending but an embrace of healthy lifestyles by the affluent. In PNAS: www.pnas.org/doi/10.1073/...

A woman riding a bicycle in Stockholm, Sweden, on September 14, 2018.

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Apr 8

bad news for freshwater quality in minnesota and midwest, very bad in the Twin Cities.

Science News @scinews.bsky.social · Apr 8

Deicing salt exacerbates freshwater salinization under climate change and human activities

www.sciencedirect.com/science/arti...

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Reposted by Alessandro Bartolomucci Lab

Elvira De Leonibus @deleonibuslab.bsky.social · Apr 3

🧠💥 For #Dopamine (DA) & #Memory lovers!

📢 New paper!! we show that memory capacity (MC) in mice can be expanded from 6 to 8 objects using low doses of a D1 receptor agonist. Higher doses? Paradoxically, they reduce MC.

#Tigem
#Consiglio Nazionale delle Ricerche

lnkd.in/d9skfGeb

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Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Apr 2

We recently published
@geroscience.bsky.social
the development and validation of the mouse social frailty index (mSFI) link.springer.com/article/10.1...

We now report a detailed step-by-step resource paper describing how to conduct the mSFI.
bio-protocol.org/en/bpdetail?...

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Reposted by Alessandro Bartolomucci Lab

Cláudia Gil @claudiagil93.bsky.social · Mar 27

🌟 Exciting News! 🌟
I am thrilled to share that my first paper as the first author, Food insecurity promotes adiposity in mice, is now published in #ObesityJournal #ObesitySociety

doi.org/10.1002/oby....

#Foodinsecurity #Obesity #PhD

1/9🧵👇

Food insecurity promotes adiposity in mice

Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecu...

doi.org

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Reposted by Alessandro Bartolomucci Lab

Andrea Galmozzi @andreagalmozzi.bsky.social · Mar 25

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

Dylan Duerre @dylanduerre.bsky.social · Mar 25

Excited to share that work from my PhD is now available in @natmetabolism.bsky.social! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D.

Link to paper: urldefense.com/v3/__https:/...

A Thread (1/15)

Haem biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue

Nature Metabolism - Inhibition of haem synthesis is shown to lead to the accumulation of branched-chain amino acids in the brown adipose tissue of mice, which reduces UCP1 levels and impairs...

urldefense.com

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Reposted by Alessandro Bartolomucci Lab

Dena Dubal @denadubal.bsky.social · Mar 6

"We could all use a little more X!" Thrilled our new study is out. Aging "wakes up" the silent X chromosome in the female brain - and this contributes cognitive resilience. Spearheaded by @margaretgadek.bsky.social in Science Advances. www.science.org/doi/10.1126/...

Aging activates escape of the silent X chromosome in the female mouse hippocampus

Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.

www.science.org

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Reposted by Alessandro Bartolomucci Lab

Magdalena Skipper @magdalenaskipper.bsky.social · Mar 6

In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”….

🧪 #AcademicSky

www.nature.com/articles/d41...

Exclusive: NIH to terminate hundreds of active research grants

Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.

www.nature.com

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