Sebastian Baumeister
@baumeister-se.bsky.social
Epidemiologist, Universität Münster
Reposted by Sebastian Baumeister
Have you seen George Davey Smith telling him the smoking findings were completely implausible at a seminar in Edinburgh 1994? youtu.be/K9pyS7EGCV8?...
Hans Eysenck (1994) personality and cancer lecture
YouTube video by Philip Corr
youtu.be
December 4, 2025 at 9:22 AM
Have you seen George Davey Smith telling him the smoking findings were completely implausible at a seminar in Edinburgh 1994? youtu.be/K9pyS7EGCV8?...
Reposted by Sebastian Baumeister
How to use LLMs in research work - a really nice introduction to coding with LLMs for research by Kohei Kawaguchi. Code and docs available in a github repo #linkoftheday
note.com/mixingale/n/...
note.com/mixingale/n/...
Leveraging AI as a Research Assistant: A Case Study in Causal Inference Implementation｜Kohei Kawaguchi-Sunada
Introduction Many data scientists are familiar with these challenges: waiting days to receive results after assigning analysis tasks to a junior analyst, or requiring multiple rounds of communication...
note.com
November 13, 2025 at 6:56 PM
How to use LLMs in research work - a really nice introduction to coding with LLMs for research by Kohei Kawaguchi. Code and docs available in a github repo #linkoftheday
note.com/mixingale/n/...
note.com/mixingale/n/...
Reposted by Sebastian Baumeister
I've had this on my reading list for awhile, but I finally got around to it and it is excellent
It is a great introduction to bounds for missing data (that I wish I read much earlier when I was first learning about them!!)
www.sciencedirect.com/science/arti...
It is a great introduction to bounds for missing data (that I wish I read much earlier when I was first learning about them!!)
www.sciencedirect.com/science/arti...
Partial identification with missing data: concepts and findings
The traditional way to cope with missing data problems has been to combine the available data with assumptions strong enough to point-identify the pro…
www.sciencedirect.com
November 4, 2025 at 4:00 PM
I've had this on my reading list for awhile, but I finally got around to it and it is excellent
It is a great introduction to bounds for missing data (that I wish I read much earlier when I was first learning about them!!)
www.sciencedirect.com/science/arti...
It is a great introduction to bounds for missing data (that I wish I read much earlier when I was first learning about them!!)
www.sciencedirect.com/science/arti...
Reposted by Sebastian Baumeister
Reposted by Sebastian Baumeister
Paul Goldsmith-Pinkham, Peter Hull, Michal Koles\'ar: Leniency Designs: An Operator's Manual https://arxiv.org/abs/2511.03572 https://arxiv.org/pdf/2511.03572 https://arxiv.org/html/2511.03572
November 6, 2025 at 6:35 AM
Paul Goldsmith-Pinkham, Peter Hull, Michal Koles\'ar: Leniency Designs: An Operator's Manual https://arxiv.org/abs/2511.03572 https://arxiv.org/pdf/2511.03572 https://arxiv.org/html/2511.03572
Reposted by Sebastian Baumeister
We wrote an article explaining why you shouldn't put several variables into a regression model and report which are statistically significant - even as exploratory research. bmjmedicine.bmj.com/content/4/1/.... How did we do?
October 27, 2025 at 5:39 PM
We wrote an article explaining why you shouldn't put several variables into a regression model and report which are statistically significant - even as exploratory research. bmjmedicine.bmj.com/content/4/1/.... How did we do?
Reposted by Sebastian Baumeister
Dismantling the Institutional Review Board (IRB), that oversees all human subjects research, is bad. Really bad.
The entire HR department at the CDC is gone. Everyone at the IRB, which makes sure studies are conducted ethically and rigorously, and the ethics office, which oversee conflicts of interest for CDC leaders and advisory committee members, were also let go.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
‘Instability and confusion’ as CDC slashes 1,300 jobs before reinstating half
Trump administration says 700 notices were sent in error, while top CDC officer says ‘they didn’t think through what they were doing’
www.theguardian.com
October 19, 2025 at 4:00 PM
Dismantling the Institutional Review Board (IRB), that oversees all human subjects research, is bad. Really bad.
Reposted by Sebastian Baumeister
Though it’s traumatic for me to bring this up, I was targeted by a group allied with Turning Point USA in 2018, with the help of Tucker Carlson on Fox. My home address circulated online and I got death threats. 1/
September 13, 2025 at 3:21 PM
Though it’s traumatic for me to bring this up, I was targeted by a group allied with Turning Point USA in 2018, with the help of Tucker Carlson on Fox. My home address circulated online and I got death threats. 1/
Reposted by Sebastian Baumeister
I wrote something about statistics under authoritarianism
Why Trump’s undermining of US statistics is so dangerous | Daniel Malinsky
Why Trump’s undermining of US statistics is so dangerous | Daniel Malinsky
From the firing of the labor statistics chief to plans for a new census, the president’s moves serve to entrench authoritarianism
www.theguardian.com
September 2, 2025 at 12:46 PM
I wrote something about statistics under authoritarianism
Reposted by Sebastian Baumeister
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
AlphaFold - A practical guide
AlphaFold - A practical guide
www.ebi.ac.uk
July 21, 2025 at 3:33 PM
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
Reposted by Sebastian Baumeister
Jana Christofer and I wrote a piece on #papermills for Laborjournal. We discuss challenges of paper mills and AI for scientific publishing. Science needs immediate solutions to correct it and prevent it from massively produced fraud.
@image-integrity.bsky.social
www.laborjournal.de/rubric/essay...
@image-integrity.bsky.social
www.laborjournal.de/rubric/essay...
July 15, 2025 at 8:39 AM
Jana Christofer and I wrote a piece on #papermills for Laborjournal. We discuss challenges of paper mills and AI for scientific publishing. Science needs immediate solutions to correct it and prevent it from massively produced fraud.
@image-integrity.bsky.social
www.laborjournal.de/rubric/essay...
@image-integrity.bsky.social
www.laborjournal.de/rubric/essay...
Reposted by Sebastian Baumeister
🚨ICYMI 🫀🧬 from @mariosgeorgakis.bsky.social & co
📄Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease
📄Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease
Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease
We present a stringent single-cell analytical framework using transcriptome-wide Mendelian
randomization and colocalization. By resolving cell-type-specific expression effects
missed by bulk methods, ...
www.cell.com
June 30, 2025 at 3:52 PM
🚨ICYMI 🫀🧬 from @mariosgeorgakis.bsky.social & co
📄Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease
📄Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease
Reposted by Sebastian Baumeister
I probably won't have time to make a video out of this.
But the materials are available online, and should be pretty self-explanatory.
Hope this is useful to some people.
privefl.github.io/statgen-cour...
But the materials are available online, and should be pretty self-explanatory.
Hope this is useful to some people.
privefl.github.io/statgen-cour...
July 4, 2025 at 3:27 PM
I probably won't have time to make a video out of this.
But the materials are available online, and should be pretty self-explanatory.
Hope this is useful to some people.
privefl.github.io/statgen-cour...
But the materials are available online, and should be pretty self-explanatory.
Hope this is useful to some people.
privefl.github.io/statgen-cour...
Reposted by Sebastian Baumeister
Due both to federal research cuts and lack of funds in state govs., a number of universities are facing hard financial times. Indiana University is handling this in part by canceling or suspending 116 academic programs, tinyurl.com/28x2cysu. 🧵 1/
tinyurl.com
July 2, 2025 at 5:34 AM
Due both to federal research cuts and lack of funds in state govs., a number of universities are facing hard financial times. Indiana University is handling this in part by canceling or suspending 116 academic programs, tinyurl.com/28x2cysu. 🧵 1/
Reposted by Sebastian Baumeister
🎉(1/4) Excited to share that our latest paper is now published!
We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP.
www.nature.com/articles/s41...
We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP.
www.nature.com/articles/s41...
Genetic influences on antidepressant side effects: a CYP2C19 gene variation and polygenic risk study in the Estonian Biobank - European Journal of Human Genetics
European Journal of Human Genetics - Genetic influences on antidepressant side effects: a CYP2C19 gene variation and polygenic risk study in the Estonian Biobank
www.nature.com
July 2, 2025 at 8:47 AM
🎉(1/4) Excited to share that our latest paper is now published!
We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP.
www.nature.com/articles/s41...
We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP.
www.nature.com/articles/s41...
Reposted by Sebastian Baumeister
about that: www.sciencedirect.com/science/arti...
Is the “well-defined intervention assumption” politically conservative?
www.sciencedirect.com
June 20, 2025 at 1:32 PM
about that: www.sciencedirect.com/science/arti...
Reposted by Sebastian Baumeister
Thanks @timpmorris.bsky.social et al - a wonderful course at UCL on Simulation - highly recommend. And huge congratulations to my colleague Ryan for completing this complex methodological review - will be so important for #DIAMOND going forward. 🎉👏🏼
DIAMOND WP2 is exploring how simulation can support target trial emulation in deprescribing research. We recently conducted a review of simulation studies - 📢preprint now here: doi.org/10.1101/2025....
We also attended a brilliant simulation course led by Tim Morris, UCL: tinyurl.com/UCLSimTraining
We also attended a brilliant simulation course led by Tim Morris, UCL: tinyurl.com/UCLSimTraining
Pharmacoepidemiology simulation study practices: A methodological review
Purpose Simulation studies are used in pharmacoepidemiology for evaluating inferential methods in a controlled setting, whereby a known data-generating mechanism allows evaluation of the performance o...
doi.org
June 2, 2025 at 8:19 PM
Thanks @timpmorris.bsky.social et al - a wonderful course at UCL on Simulation - highly recommend. And huge congratulations to my colleague Ryan for completing this complex methodological review - will be so important for #DIAMOND going forward. 🎉👏🏼
Reposted by Sebastian Baumeister
Harvard today, your institution tomorrow.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
May 22, 2025 at 6:38 PM
Harvard today, your institution tomorrow.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
It's all part of the Project 2025 plan to destroy high education in America.
All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
Reposted by Sebastian Baumeister
🎫Registration open for 1-day hybrid event: “Target trial emulation and other frameworks: The role and potential of observational data for evaluating effects of interventions”. 📆26th June. tinyurl.com/dash-tte. Hosted by LSHTM Centre for Data & Statistical Science for Health. @lshtm-dash.bsky.social
Target trial emulation and other frameworks | LSHTM
Large scale observational data are increasingly available for healthcare research, including from electronic health records and disease registries. Target trial emulation (TTE) provides a framework
tinyurl.com
May 16, 2025 at 9:25 AM
🎫Registration open for 1-day hybrid event: “Target trial emulation and other frameworks: The role and potential of observational data for evaluating effects of interventions”. 📆26th June. tinyurl.com/dash-tte. Hosted by LSHTM Centre for Data & Statistical Science for Health. @lshtm-dash.bsky.social
Reposted by Sebastian Baumeister
Watching Scott Zimmerman and Erin Ferguson lead a workshop on reproducible research and multiverse analysis. It's their practice for a workshop at #EpiResearch #SER 2025. epiresearch.org/annual-meeti... Drawing on Erin's paper: link.springer.com/article/10.1... So cool.
May 8, 2025 at 9:28 PM
Watching Scott Zimmerman and Erin Ferguson lead a workshop on reproducible research and multiverse analysis. It's their practice for a workshop at #EpiResearch #SER 2025. epiresearch.org/annual-meeti... Drawing on Erin's paper: link.springer.com/article/10.1... So cool.
Reposted by Sebastian Baumeister
📣📣 Thrilled to see this cool work finally out in the wild! "Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology & prediction" www.nature.com/articles/s41...
Loads of cool findings including MR for alcohol usage -> increased variance in BC traits
Loads of cool findings including MR for alcohol usage -> increased variance in BC traits
May 7, 2025 at 7:21 PM
📣📣 Thrilled to see this cool work finally out in the wild! "Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology & prediction" www.nature.com/articles/s41...
Loads of cool findings including MR for alcohol usage -> increased variance in BC traits
Loads of cool findings including MR for alcohol usage -> increased variance in BC traits
Reposted by Sebastian Baumeister
I have been in biomedical science for over a decade & I independent of that have followed @joshtpm.bsky.social and @talkingpointsmemo.com for political commentary. Those worlds now converge as Josh is one of the key political reporters with relentless focus on what is happening at NIH/NSF.
Why Do They Have It In For Biomedical Research?
Here is a brief follow-up on the question TPM Reader MA addresses...
talkingpointsmemo.com
May 7, 2025 at 5:38 PM
I have been in biomedical science for over a decade & I independent of that have followed @joshtpm.bsky.social and @talkingpointsmemo.com for political commentary. Those worlds now converge as Josh is one of the key political reporters with relentless focus on what is happening at NIH/NSF.
Reposted by Sebastian Baumeister
Happy to share our new (open access) article in the Canadian Journal of Economics on people’s willingness to donate DNA for science and its relationship with economic incentives and preferences. A brief thread on what we learned (1/4):
doi.org/10.1111/caje...
doi.org/10.1111/caje...
“The risks cannot be compensated”: The willingness to donate DNA for science and its relationship with economic preferences
The accumulation of large genetic data is crucial for the scientific advancement of genetic research and precision medicine, but various participation biases threaten the validity of genetic research...
doi.org
May 7, 2025 at 8:49 AM
Happy to share our new (open access) article in the Canadian Journal of Economics on people’s willingness to donate DNA for science and its relationship with economic incentives and preferences. A brief thread on what we learned (1/4):
doi.org/10.1111/caje...
doi.org/10.1111/caje...
Reposted by Sebastian Baumeister
Big news for health data research and population diversity: The Mexico City Prospective Study data are now available securely to approved researchers worldwide. www.ndph.ox.ac.uk/news/latin-a...
Cohort description: www.ctsu.ox.ac.uk/research/pro...
Cohort description: www.ctsu.ox.ac.uk/research/pro...
Latin-American genetic data available securely to approved researchers worldwide/Datos genéticos latinoamericanos disponibles para investigadores de todo el mundo
www.ndph.ox.ac.uk
May 2, 2025 at 9:05 AM
Big news for health data research and population diversity: The Mexico City Prospective Study data are now available securely to approved researchers worldwide. www.ndph.ox.ac.uk/news/latin-a...
Cohort description: www.ctsu.ox.ac.uk/research/pro...
Cohort description: www.ctsu.ox.ac.uk/research/pro...