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Ching-Shin Huang

@chingshinhuang.bsky.social

220 followers 760 following 1 posts

Structural biologist. Open science supporter. Opinions are my own.

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Ching-Shin Huang @chingshinhuang.bsky.social · Jul 19

Working with @astbury-bsl.bsky.social, we report cryo-EM structures of CD163 in its apo state and in complex with haptoglobin–hemoglobin (HpHb), and propose a framework of how CD163-mediated endocytosis clears different isoforms of HpHb. Please check it out on @plosbiology.org!

PLOS Biology @plosbiology.org · Jul 15

The #macrophage CD163 receptor clears free #hemoglobin in the bloodstream by binding the HpHb complex. The #cryoEM structure of CD163-HpHb complex, by @chingshinhuang.bsky.social &co, reveals how CD163-mediated endocytosis clears different HpHb isoforms @plosbiology.org 🧪 plos.io/4nNBbGI

Top: Cryo-EM map of the CD163/Hp(1–1)Hb complex colored by each component and shown in two side views and one bottom view. A map in transparent representation is contoured at a low level to show electron density for the unresolved flexible domain D1 and unbound HpHb protomer. Bottom: Cryo-EM map of the CD163/HpSPHb complex colored by each component and shown in two side views and one bottom view. A map in transparent representation is contoured at a low level to show electron density for the flexible peripheral regions.

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Reposted by Ching-Shin Huang

Astbury Biostructure Laboratory @astbury-bsl.bsky.social · Feb 20

Really pleased to share this story in collaboration with our fantastic industry partners @chingshinhuang.bsky.social !

bioRxivpreprint @biorxivpreprint.bsky.social · Feb 20

Structural elucidation of the haptoglobin-hemoglobin clearance mechanism by macrophage scavenger receptor CD163 https://www.biorxiv.org/content/10.1101/2025.02.14.638171v1

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Reposted by Ching-Shin Huang

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · Dec 16

oldies but goodies : A bioRxiv template for Microsoft Word

github.com/chrelli/bioR...

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Reposted by Ching-Shin Huang

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · Dec 3

Three BioML starter packs now!

Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok

DM if you want to be included (or nominate people who should be!)

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Reposted by Ching-Shin Huang

Bird account @dialecticbio.bsky.social · Mar 3

Been thinking about creating a collection of good protein structure figures, as inspiration for my own work.

#1 www.nature.com/articles/s41...

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Reposted by Ching-Shin Huang

Jon Lim, MRCP PhD @drjonlim.bsky.social · Nov 23

🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov

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Reposted by Ching-Shin Huang

Science News @scinews.bsky.social · Nov 30

Here is a brief summary of academic journals and news account.

Please help me add more accounts to this list!

go.bsky.app/hCfhqn

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Reposted by Ching-Shin Huang

Razvan Borza @rborza.bsky.social · Nov 17

⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️

🔄Share to help people finding its topic/field

- STRUCTURAL BIOLOGY

Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...

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Reposted by Ching-Shin Huang

Kate Michie @kmichie.bsky.social · Nov 17

So many keen peeps interested in structural biology.. we have a new unit cell. 🧶🧬
go.bsky.app/HByHiW6

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Reposted by Ching-Shin Huang

Kate Michie @kmichie.bsky.social · Nov 17

So many people added to pack 1 this weekend we had to make pack 2. Makes sure you refresh for followers on pack one to see them all!
🧶🧬

go.bsky.app/DDetSBp

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