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Dan MacLean

@danmaclean.bsky.social

160 followers 570 following 66 posts

Head of Bioinformatics at The Sainsbury Laboratory, Hon Professor UEA Computer Science. Likes genomics, stats, proteomics, bioinformatics, R user, Python wrangler. Wiganer.

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Dan MacLean @danmaclean.bsky.social · Nov 18

I wrote a handy recipe book for R and Bioinformatics. Available through Packt. www.packtpub.com/en-us/produc...

Reposted by Dan MacLean

Andrew Heiss @andrew.heiss.phd · 6h

I really really really liked The Oatmeal’s take on AI here theoatmeal.com/comics/ai_art

A cartoonist's review of AI art - The Oatmeal

This is a comic about AI art.

theoatmeal.com

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Reposted by Dan MacLean

Nick Talbot @talbotlabtsl.bsky.social · 1d

New pre-print from our group showing remarkable synchrony of proliferative growth and regulated cell death during plant infection- each conidial cell has a different fate - by the rice blast fungus. Led by Alice Eseola with @osesmir.bsky.social Lauren Ryder @danmaclean.bsky.social and Martin Egan

bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · 1d

Synchronous spatio-temporal control of autophagy and organelle trafficking is necessary for appressorium-mediated plant infection by Magnaporthe oryzae https://www.biorxiv.org/content/10.1101/2025.10.06.680644v1

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Dan MacLean @danmaclean.bsky.social · 6d

2️⃣ For the love of all that remains sane in the world.

Reposted by Dan MacLean

The Abominable Dr. Vibes @benmckenna.bsky.social · 13d

Great to hear Burnham's been to Mancwalk 2000.

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Reposted by Dan MacLean

Christian Minich @christiannolan.bsky.social · 22d

Normalize never saying "leverage" or "utilize" as a verb. Tempted? "Use" is right there!

Simple words are better words

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Reposted by Dan MacLean

SomersetWhovian 💙 🇺🇦 📎 @clairecopperman.bsky.social · Sep 1

"It has never been clearer: this is a class war, mediated through one person."
Love this article from @zoesqwilliams.bsky.social. I snorted several times, but she makes some serious points: in the eyes of the tabloids, the working class Rayner can't win, whatever she does.

Why are the tabloids so enraged about every aspect of Angela Rayner’s life? | Zoe Williams

Whether it’s her housing, clothes, the restaurants she goes to, or the fact she watches opera and drinks wine, she can apparently do nothing right, writes Guardian columnist Zoe Williams

www.theguardian.com

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Dan MacLean @danmaclean.bsky.social · Jul 31

$ ls -laht
drwxrwsr-x 3 uname grp 27 Nov 16 2006 .nautilus
drwxrws--- 3 uname grp 26 Nov 16 2006 .metacity
-rwxrwx--- 1 uname grp 26 Nov 16 2006 .dmrc

😐

Reposted by Dan MacLean

GigaScience Journal @gigascience.bsky.social · Jul 22

Chris outlining the different AI coding agents that can be used for ontology development. Working on documenting best practices for this ai4curation.GitHub.io/aidocs #BOSC2025 #ISMBECCB2025

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Reposted by Dan MacLean

GigaScience Journal @gigascience.bsky.social · Jul 22

Today #BOSC2025 and #BOKR (formerly Bioontologies) COSI’s, Chris Mungall is doing the keynote on Open KBs in the age of generative AI #ISMBECCB2025

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Reposted by Dan MacLean

Darakhshan Nehal @darakhshann.bsky.social · Jul 22

*Learning visualization in Python as an R user*
#ggplot

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Reposted by Dan MacLean

fesshole 🧻 @fesshole.bsky.social · Jul 21

I work with a lot of very intelligent people - the experts in a very select field - yet every morning they fight over the parking spots in the shade. By lunchtime they're all in full sun and my unwanted "sunny" spot keeps my car nice and cool. They never learn.

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Reposted by Dan MacLean

Claus Wilke @clauswilke.com · Jul 12

AlphaFold is great, but contrary to public opinion it has not completely solved the protein folding problem. Much work remains to be done.
clauswilke.substack.com/p/no-alphafo...

No, AlphaFold has not completely solved protein folding

Biology is hard. Yes, even for AI.

clauswilke.substack.com

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Dan MacLean @danmaclean.bsky.social · Jul 13

open.substack.com/pub/clauswil...

No, AlphaFold has not completely solved protein folding

Biology is hard. Yes, even for AI.

open.substack.com

Reposted by Dan MacLean

Michael Love @mikelove.bsky.social · Jul 13

I recently ran a session at CSAMA with Laurent Gatto and this is the way. "Good enough" with knowledge of the tools that can help you get there. Here's some of the recs from the paper.

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Dan MacLean @danmaclean.bsky.social · Jul 10

😀 This is good to hear. My kid is past kpop phase so won't choose it, but I put it on my mental watchlist as a candidate for one of those nothing else on, dad can still choose some good things, type evenings.

Dan MacLean @danmaclean.bsky.social · Jul 6

Dan MacLean @danmaclean.bsky.social · Jun 19

Nice. An API is like a structured set of URLs for querying data that you can send to someone's computer and they'll send you an appropriate response. Eg api.mcdonalds.com/menu/sold/cheeseburger might return 31234543219494938263628 (some big number, anyway)

Api.mcdonalds.com

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Reposted by Dan MacLean

Mel Brooks @officialmelbrooks.bsky.social · Jun 12

I told you we’d be back

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Dan MacLean @danmaclean.bsky.social · May 23

If it was a small sample I might try Internet archives set of scanned magazines, iirc they have ads scanned or you might find it in reviews archive.org/details/comp...

Internet Archive: Digital Library of Free & Borrowable Texts, Movies, Music & Wayback Machine

archive.org