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deepjdog.bsky.social
Jiri Hofbrucker
@deepjdog.bsky.social
280 followers 670 following 19 posts
Empowering neuroscientists with fiber-based microscopic systems for imaging at any brain depth CTO at DeepEn, @deepen-imaging.bsky.social ( https://deepen-imaging.com/ )
deepen-imaging.com
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · Dec 3
Hi all! I’m developing a fiber endoscope that uses a 100-micron fiber to perform fluorescence imaging deep in tissues. I’m especially keen to connect with neuroscientists and anyone passionate about fluorescence imaging. Let’s share ideas and collaborate! #firstskeet #neuroscience #calciumimaging
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · 1d
🧠What do neuroscientists think of DeepEn's holographic microendoscope?
How can they use it to study learning and memory processes?
Can it enable voltage imaging in deep brain structures to study processes behind neuronal firing?

⭐ Check the Nature’s article:
www.nature.com/articles/d42...
High-resolution insights from the deep brain
Discover the world’s best science and medicine | Nature.com
www.nature.com
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Reposted by Jiri Hofbrucker
smikulovic.bsky.social
Sanja Mikulovic @smikulovic.bsky.social · Sep 4
Excited to share we’ve been awarded the ERC StG 🎉 for our project ProSocial, studying neural mechanisms of prosocial behavior in health & disease. Huge thanks to my group for their amazing work & to great colleagues for their support! Positions opening soon—reach out if interested!
erc.europa.eu
European Research Council (ERC) @erc.europa.eu · Sep 4
📣 The ERC Starting Grant call results are out!

Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!

➡️ buff.ly/IsafuFh

#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · Sep 2
Are you the kind of neuroscientist who scripts analysis or can’t resist tinkering with hardware?
At DeepEn we’re building a fluorescence microscope to image deep in the brain through a single optical fiber. Join us to hack the future of neuroimaging: #ScienceJob
www.linkedin.com/jobs/view/42...
DeepEn hiring Neuroscience Imaging Scientist (Microscopy + Applications) in Jena, Thuringia, Germany | LinkedIn
Posted 8:01:32 PM. DeepEn develops minimally invasive microendoscopes for neuroscience applications. We transform a…See this and similar jobs on LinkedIn.
www.linkedin.com
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Reposted by Jiri Hofbrucker
gerbi-gmb.de
German BioImaging @gerbi-gmb.de · Sep 1
⏰ Reminder: The early bird registration and abstract submission for our 5th Day of Intravital Microscopy close on September 5!
Don’t miss your chance to join us in Tübingen on 18–19 Sept. Secure your spot today!
👉 bit.ly/3IOlJtJ
5th Day of Intravital Microscopy - German BioImaging
Intravital microscopy (IVM) enables the observation and precise quantification of cellular processes within native tissue microenvironments, with resolutions unmatched by other techniques. This powerf...
bit.ly
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danai-lama.bsky.social
Danai Riga @danai-lama.bsky.social · Sep 1
Beautiful work!
tjryan.bsky.social
Tomás Ryan @tjryan.bsky.social · Sep 1
Updated (final) preprint below:

www.biorxiv.org/content/10.1...
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Reposted by Jiri Hofbrucker
tobiasackels.bsky.social
Tobias Ackels @tobiasackels.bsky.social · Jun 11
Fun collaborative work together with the amazing lab of @sophiesteculorum.bsky.social now published!
sophiesteculorum.bsky.social
Sophie Steculorum @sophiesteculorum.bsky.social · Jun 11
📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social‬ and all co-authors, especially @andreas-t-schaefer.bsky.social and ‪@tobiasackels.bsky.social‬ 🙌! ‬‬
www.nature.com/articles/s42...
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
www.nature.com
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Reposted by Jiri Hofbrucker
neurowithmelike.bsky.social
Melike Eren @neurowithmelike.bsky.social · Jul 7
www.nature.com/articles/s41...
A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution - Nature
A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promise...
www.nature.com
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · Jul 7
A fantastic overview of where three-photon microscopy stands relative to existing methods. It's clear that while the technology is still maturing, its advantages for deep-brain imaging!
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melcooperphd.bsky.social
Melissa Cooper, PhD @melcooperphd.bsky.social · May 14
Hippocampal vasculature is so pretty 😍
(mouse hippocampus perfused with Tomato Lectin and cleared)
#Neuroscience #Microscopy
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Reposted by Jiri Hofbrucker
marcaurelbusche.bsky.social
Marc Aurel Busche @marcaurelbusche.bsky.social · May 8
Where does Alzheimer’s begin in the brain? Our study in @cp-neuron.bsky.social shows that the earliest amyloid-related neuronal dysfunction emerges selectively in deep cortical layers (layers 5/6), targeting fast-spiking parvalbumin interneurons via reductions in NPTX2.
www.cell.com/neuron/fullt...
Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo
Papanikolaou et al. show that deep-layer cortical neurons exhibit abnormally prolonged Ca2+ transients early in Alzheimer’s mouse models. This is linked to suppressed activity and altered tuning of fa...
www.cell.com
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Reposted by Jiri Hofbrucker
nvladimus.bsky.social
Nikita Vladimirov @nvladimus.bsky.social · Jan 20
Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!
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Reposted by Jiri Hofbrucker
petramoce.bsky.social
Petra Mocellin @petramoce.bsky.social · May 1
Too excited not to share this beauty!
#fluorescenceFriday (but a day earlier)

TH staining in cyan
Virus injection in magenta

Zona Incerta is definitely a tough cookie 🍪 but getting there!
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · May 3
Beautiful axons indeed! A quick technical question. What technique did you use to target the amygdala during ferrule implantation?
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Reposted by Jiri Hofbrucker
neuronsinactionpl.bsky.social
6th Neurons in Action Conference @neuronsinactionpl.bsky.social · Mar 30
🧠 GABA! 🔬✨Explore groundbreaking research on the GABAergic system and its role in health and disease in humans and rodents.
Learn more by joining us #NeuronsInAction2025!
📍the Nencki Institute, Warsaw, Poland
📅 27-31 May, 2025
#nia2025 #neuronsinaction2025 #neuroscience #brain #nenckiinstitute
A picture of a gigaseal during electrophysiological recording in neuron.
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Reposted by Jiri Hofbrucker
mfendt.bsky.social
Markus Fendt @mfendt.bsky.social · Mar 28
Excellent Norbert Elsner Lecture by Rui Costa @ruimcosta.bsky.social, Göttingen Meeting of @neurowissg.bsky.social
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deepen-imaging.bsky.social
deepen-imaging.bsky.social @deepen-imaging.bsky.social · Mar 20
📣 1 week to go!

Get ready for a LIVE DEMO of our Holographic Microendoscope for high resolution deep brain imaging 🧠 🔬

📍at the 16th Göttingen Meeting of the German Neuroscience Society

Come to our booth and tell us about your research ideas!
#NWG2025
#GöttingenMeeting
#Neuroscience
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Reposted by Jiri Hofbrucker
briannaegeorge.bsky.social
Brianna George, PhD @briannaegeorge.bsky.social · Mar 14
Just so happened to see this beauty today while recording in Kash Lab @superkash.bsky.social. Happy #FluorescenceFriday 🤩🔬
In vivo image captured of a neuron labeled with a calcium indicator
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Reposted by Jiri Hofbrucker
alleninstitute.org
Allen Institute @alleninstitute.org · Mar 13
Happy #BrainAwarenessWeek! Join this international celebration of the brain with this visual exploration of its makeup and neighborhoods: alleninstitute.org/news/what-ar...

🧠📈 @danafoundation.bsky.social
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Reposted by Jiri Hofbrucker
microscopy.confocalnl.com
Confocal NL @microscopy.confocalnl.com · Mar 10
Do you want to join a great team and work on cutting-edge confocal microscopy systems?

Join us at Confocal NL as a Product Application Specialist and help researchers globally accelerate their discoveries with our disruptive technology!

Apply here: confocal.recruitee.com/o/product-ap...
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maclab.bsky.social
MAC lab @maclab.bsky.social · Mar 10
The MAC lab is hiring a full-time lab manager to start in June! You will have the opportunity to conduct research projects relating to long-term memory and concept knowledge (methods include online and in-person behavioral experiments, fMRI, TMS). Apply by March 26 careers.drexel.edu/cw/en-us/job...
MAC lab
How does our prior knowledge impact how we learn new information? How do memories change over time? We use cognitive neuroscience methods to understand how the brain stores, organizes, and transforms ...
www.memoryandconceptslab.org
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nerflabs.bsky.social
NERF @nerflabs.bsky.social · Feb 11
As part of #NEUROGATE, the Haesler lab is helping develop a holographic endoscope for high-resolution, deep-brain imaging. Supported by a €2.5M EIC grant, this ultra-thin fiber technology could transform neuroscience & neurotech.
nerf.be/en/news#/new...
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czechacademy.bsky.social
Czech Academy of Sciences @czechacademy.bsky.social · Feb 3
The research team from @leibnizipht.bsky.social, DeepEn, the Institute of Scientific Instruments @czechacademy.bsky.social & @nerflabs.bsky.social is developing this innovative imaging technology to visualize neuronal processes in living organisms with high precision.
“With NEUROGATE, we are taking it to the next level to study neuronal activity under natural conditions with unprecedented precision. These findings could significantly expand our understanding of neurological diseases.” Tomáš Čižmár, Institute of Scientific Instruments of the CAS
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dgn-ev.bsky.social
Deutsche Gesellschaft für Neurologie (DGN) e.V. @dgn-ev.bsky.social · Mar 7
Dr. Jörg Philipps erhält den Robert Wartenberg-Preis 2025 für seine Arbeiten zu diagnostischen Anwendungen des hochauflösenden Nervenultraschalls in der #Neurologie. Herzlichen Glückwunsch! 👉 dgn.org/artikel/robe... #neuroskyence
Foto:© DGN/Claudius Pflug
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svi.nl
SVI Huygens @svi.nl · Mar 6
Happy to provide a #TIM2025 Workshop and present together with Dr. Peter Hemmerich, from the CF Imaging of the Leibniz Institute on Aging – FLI, image Quality Control, restoration, deconvolution, denoising, and analysis of confocal and STED data. #microscopy #science
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deepjdog.bsky.social
Jiri Hofbrucker @deepjdog.bsky.social · Mar 6
Excited to attend the 16th Göttingen Meeting of the @neurowissg.bsky.social in three weeks! Looking forward to insightful discussions and cutting-edge research. If you're attending, let’s connect—I’d love to catch up in person!
See you in Göttingen! 🚀🔬 #Neuroscience #GöttingenMeeting #NWG2025
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