Francisco Amaro
donpaquito.bsky.social
Francisco Amaro
@donpaquito.bsky.social
Microbiologist. Assistant Professor at Complutense University of Madrid. Bacteria-protist interactions as drivers of bacterial virulence and persistence
Reposted by Francisco Amaro
Why are there so few #pathogens, and what determines their emergence? @jdrakephd.bsky.social ‬argues that #ecological and #evolutionary forces (host availability, geographic exposure and microbial innovation) will shape future human diseases. 🧪
plos.io/4mUst87
August 22, 2025 at 8:58 AM
Reposted by Francisco Amaro
(1/5)For over a century, the hunt for new antibiotics has focused almost exclusively on bacteria and fungi. Today, that paradigm shifts. By coupling state-of-the-art AI with the vast, largely uncharted diversity of Archaea, we open a new frontier for molecular discovery.
Deep learning reveals antibiotics in the archaeal proteome - Nature Microbiology
Use of artificial intelligence to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising ...
www.nature.com
August 12, 2025 at 11:11 AM
Reposted by Francisco Amaro
Excited to have our new mini review on Microbiome Metabolism out today in I&I as part of the @asm.org New Voices in Microbiology collection! Check it out!

🧫🧪

journals.asm.org/doi/10.1128/...
Infections as ecosystems: community metabolic interactions in microbial pathogenesis | Infection and Immunity
Microbial communities are present on nearly every surface of the human body. These microbiomes exist as dynamic ecosystems that are influenced by heterogeneous nutritional and chemical landscapes, the...
journals.asm.org
August 4, 2025 at 4:36 PM
Reposted by Francisco Amaro
La odisea de tres mujeres y el BO-112, la molécula que engaña al cáncer
elpais.com/ciencia/2025...
La odisea de tres mujeres y el BO-112, la molécula que engaña al cáncer
La líder científica, la empresaria y una paciente libre de enfermedad se reúnen para contar la historia completa del prometedor fármaco experimental español contra los tumores
elpais.com
August 3, 2025 at 8:21 AM
Reposted by Francisco Amaro
chemical crosstalk at a distance of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘴𝘺𝘳𝘪𝘯𝘨𝘢𝘦 with 𝘗𝘰𝘭𝘺𝘴𝘱𝘩𝘰𝘯𝘥𝘺𝘭𝘪𝘶𝘮 𝘱𝘢𝘭𝘭𝘪𝘥𝘶𝘮 amoebae. oh nos, this does not end well for the amoebas...

www.cell.com/cell/fulltex...
#MicroSky
A chemical radar allows bacteria to detect and kill predators
Pseudomonas syringae can detect and kill microbial predators via a chemical radar (Cra), which also allows the bacterium to infect plants despite predation pressure.
www.cell.com
April 3, 2025 at 2:03 PM
Reposted by Francisco Amaro
Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control

@cp-iscience.bsky.social from Frank Delvigne

www.cell.com/iscience/ful...
Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control
Biological sciences; Microbiology; Microbiofilms
www.cell.com
March 25, 2025 at 6:06 PM
Reposted by Francisco Amaro
Hoy 24 de marzo se conmemora el Día Mundial de la Tuberculosis, en recuerdo del día en que se publicó la identificación de Mycobacterium tuberculosis como la bacteria responsable de la enfermedad. Robert Koch recibió el Premio Nobel por ello en 1905.
www.nobelprize.org/prizes/medic...
Nobel Prize in Physiology or Medicine 1905
The Nobel Prize in Physiology or Medicine 1905 was awarded to Robert Koch "for his investigations and discoveries in relation to tuberculosis"
www.nobelprize.org
March 24, 2025 at 6:17 PM
Reposted by Francisco Amaro
Despite thousands of years of dealing with tuberculosis, it remains the leading cause of death by infectious diseases worldwide. Can multi-drug resistant TB be combated? asm.org/Articles/202... #WorldTBDay
Ending Tuberculosis in the Face of Antimicrobial Resistance | ASM.org
Despite thousands of years of dealing with tuberculosis, it remains the leading cause of death by infectious diseases worldwide. Can multi-drug resistant TB be combated?
asm.org
March 24, 2025 at 7:12 PM
Reposted by Francisco Amaro
When a person is diagnosed with #tuberculosis, one of their first questions is often, “Why did I get tuberculosis? Why me?” 💬

Explore a recent Seminar which aims to help healthcare providers identify those at risk of TB & address patient concerns: tinyurl.com/3pvhxtbp #WorldTBDay
March 24, 2025 at 3:17 PM
Reposted by Francisco Amaro
The gut-lung axis: Protozoa join the party #protists #protistsonsky #holobiont
www.sciencedirect.com
January 21, 2025 at 5:00 PM
Reposted by Francisco Amaro
Another newly discovered mechanism of bacteria inhibiting competitors - increasing their sensitivity to phages - fascinating
www.nature.com/articles/s41...
Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology
A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.
www.nature.com
January 9, 2025 at 6:56 AM
Reposted by Francisco Amaro
Protists as mediators of complex microbial and viral associations www.biorxiv.org/content/10.1... #jcampubs
January 2, 2025 at 5:06 PM
Reposted by Francisco Amaro
Sharing in #BlueSky a 2023 review on #T6SS that I loved co-authoring with my fantastic friend and collaborator @lukeallsopp.bsky.social He coined the catchy, musical first part of our title: "Killing in the Name of: T6SS Structure and Effector Diversity" Check it out: buff.ly/3Zzh0Rz #Microbiology
December 14, 2024 at 8:52 PM
Reposted by Francisco Amaro
Sepsis is a life-threatening, heterogeneous disorder involving a dysregulated immune response to infection. Research to identify subtypes and targeted therapies for host dysregulation is ongoing #idsky #EMIMCC #medsky
www.nejm.org/doi/full/10....
December 10, 2024 at 9:56 PM
Reposted by Francisco Amaro
Different approaches to preparing and sequencing bacterial RNA libraries capture comparable transcriptional profiles:
journals.asm.org/doi/10.1128/...

#microsky #PsWatch #bacteria
RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis | Microbiology Spectrum
RNA sequencing (RNA-seq) has revolutionized biology, but many steps in RNA-seq workflows can introduce variance, potentially compromising reproducibility. While reproducibility in RNA-seq has been tho...
journals.asm.org
December 5, 2024 at 11:07 PM
Reposted by Francisco Amaro
Crazy stuff in PNAS

dental plaque bacterium 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘮𝘢𝘵𝘳𝘶𝘤𝘩𝘰𝘵𝘪𝘪 can divide into an unprecedented 14 daughter cells at once—then each daughter cell starts growing immediately in a rare process called multiple fission, achieving 0.5 mm per day of expansion

www.snexplores.org/article/bact...
These mouth bacteria use a new type of cell division to make 14 cells at once
The newfound strategy seen in C. matruchotii might help oral bacteria recover lost territory after each eviction by toothbrushing.
www.snexplores.org
November 22, 2024 at 9:54 PM
Reposted by Francisco Amaro
@lthwatermicro.bsky.social glad to see you here on 🔵bsky, catherine 👋

why not start here with the eye-opening video of "looking closer & closer at 𝘌. 𝘤𝘰𝘭𝘪" that you posted on 𝕏 on Apr 10, 2019 ?
#MicroSky
November 28, 2024 at 4:24 PM
Reposted by Francisco Amaro
@kellygoldlust.bsky.social glad to see you here, kelly 😊 you might have noticed that we featured your paper in STC >
schaechter.asmblog.org/schaechter/2...
Through The Pilus
by Roberto — Among the many mechanisms of bacterial horizontal gene transfer, conjugation, the plasmid-mediated cell-to-cell movement of DNA, holds a special place in the heart of this old-timer E. co...
schaechter.asmblog.org
November 26, 2024 at 12:55 PM
Reposted by Francisco Amaro
Just did my first Starter Pack, I think it can be useful. Let me know if you miss any journal and I will add it. Enjoy!! go.bsky.app/QPFZpj9
November 25, 2024 at 8:26 PM
Reposted by Francisco Amaro
@jamesweiss.bsky.social @jamesweiss.bsky.social we would very much like to see your marvelous clip of Leptophrys here again (you had it on 𝕏 in 2020)
#ProtistsOnSky
November 22, 2024 at 2:41 PM
Reposted by Francisco Amaro
Extremely happy to see the final published version of this study out in Nature Ecology and Evolution www.nature.com/articles/s41...
I really think this is one of our most important contributions to the field!
August 28, 2024 at 9:42 AM
Reposted by Francisco Amaro

Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation

#TrendsMicrobiol Spotlight by Elizabeth Duan, @oliviakosterlitz.bsky.social and Benjamin Kerr

on the Nat Eco Evo paper from @sanmillan.bsky.social group

www.cell.com/trends/micro...
Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation
While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating ge...
www.cell.com
November 20, 2024 at 8:29 AM