Lightnews — Scholar-powered news

Reposted by Pawel Grzechnik

Molecular and Cellular Function, University of Manchester @mcf-uom.bsky.social · Jul 17

We are excited to announce that Professor Graham Pavitt, Chair in Molecular Biology, has been appointed as our new Head of Division!
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!

research.manchester.ac.uk/en/persons/g...

Graham Pavitt

research.manchester.ac.uk

2 5

Reposted by Pawel Grzechnik

Molecular and Cellular Function, University of Manchester @mcf-uom.bsky.social · Mar 4

Early-career fellowships at the University of Manchester!

To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:

www.bmh.manchester.ac.uk/research/sup...

Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester

Find out about and apply for a Bicentenary Early Career Research Fellowship.

www.bmh.manchester.ac.uk

7 4

Reposted by Pawel Grzechnik

Sankari Nagarajan @sankarinagarajan.bsky.social · Mar 4

Exciting PhD opportunity available in my lab for the students from Black heritage background. Apply soon. 🤞🤞🤞
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social

CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity

📅 Deadline: 4 April

🔗 crukcentre.manchester.ac.uk/study/resear...

Research Opportunities - Cancer Research UK Manchester Centre

Explore the range of postgraduate cancer research opportunities available in Manchester.

crukcentre.manchester.ac.uk

2 2

Reposted by Pawel Grzechnik

Sankari Nagarajan @sankarinagarajan.bsky.social · Mar 4

Our lab's very first manuscript is out in BioRxiv. Hope this would be interesting for breast cancer scientists: www.biorxiv.org/content/10.1... @mcf-uom.bsky.social @mcr-breastcentre.bsky.social @mcrcnews.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social

Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Gene expression is tightly controlled by DNA elements called enhancers by associating with lineage-specific transcription factors. These enhancers transcribe non-coding RNAs (called enhancer RNAs or e...

www.biorxiv.org

3 4

Reposted by Pawel Grzechnik

Sankari Nagarajan @sankarinagarajan.bsky.social · Mar 4

A fantastic postdoc opportunity available for talented PhD graduates to work in our CRUK funded PhD project.
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social

jobs.manchester.ac.uk

5 7

Pawel Grzechnik @grzechnikpawel.bsky.social · Feb 28

Which side are you on?

1

Reposted by Pawel Grzechnik

Willem van Schaik @wvschaik.bsky.social · Feb 28

You can donate to support Ukraine's defence, humanitarian demining, medical aid, the rebuilding of Ukraine or education & science here: u24.gov.ua

I just donated. Slava Ukraini!

UNITED24 - The initiative of the President of Ukraine

UNITED24 was launched by the President of Ukraine Volodymyr Zelenskyy as the main venue for collecting charitable donations in support of Ukraine. Funds will be transferred to the official accounts of...

u24.gov.ua

1 19 21

Pawel Grzechnik @grzechnikpawel.bsky.social · Feb 28

🇺🇦

2

Reposted by Pawel Grzechnik

Lea H. Gregersen @gregersenlab.bsky.social · Feb 21

Another chance to join our group! Center for Gene Expression has 2 or more postdoc positions @ucph.bsky.social in wonderful Copenhagen. Want to join our team to work on transcriptional regulation? More information at: gregersenlab.com Deadline March 18. Apply here: jobportal.ku.dk/phd/?show=16...

Gegersen Lab

The aim of the lab is to understand regulation of transcription and co-transcriptional processing in human cells

gregersenlab.com

3 3

Reposted by Pawel Grzechnik

Pradeepa Madapura @pradeepmadapura.bsky.social · Feb 13

We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5

a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them .

ALT: a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them .

media.tenor.com

25 19

Reposted by Pawel Grzechnik

Lea H. Gregersen @gregersenlab.bsky.social · Feb 13

We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...

9 6

Reposted by Pawel Grzechnik

Trends in Microbiology @cp-trendsmicrobiol.bsky.social · Feb 6

Pls. share: We're putting together a series on inequalities associated with academic mobility.

If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at [email protected].

#MicroSky

12 9

Reposted by Pawel Grzechnik

Suyang Zhang @suyangzhang.bsky.social · Feb 3

Ever wondered how Pol II speed is controlled during productive elongation?
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription

www.biorxiv.org/content/10.1...

4 19 76

Reposted by Pawel Grzechnik

Lovorka Stojić @loverna.bsky.social · Jan 23

📢1/12 Happy to share our first bluetutorial & our latest preprint. In this work, we discovered RSRC2 as a novel RNA-binding protein (RBP) with a dual function in cell division whose activity can be (lnc)RNA-mediated. #lncRNA #RBP #Mitosis
www.biorxiv.org/content/10.1...

The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1

Mitotic fidelity depends on proper chromosome alignment at the spindle equator, a process known as chromosome congression, driven by well-established protein networks. Whereas RNA-binding proteins and...

www.biorxiv.org

2 16 42

Pawel Grzechnik @grzechnikpawel.bsky.social · Jan 24

We joined the Laboratory Efficiency Assessment Framework (LEAF), reduced laboratory waste and energy usage, and made the lab more sustainable overall.
And so we got the LEAF GOLD award!

1 1 8

Reposted by Pawel Grzechnik

Craig Kaplan @triggerloop.bsky.social · Nov 27

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...

Controlling Transcription Elongation and Termination: More Than a Means to An End

www.sciencedirect.com

2 25 50

Reposted by Pawel Grzechnik

Craig Kaplan @triggerloop.bsky.social · Nov 27

Pawel Grzechnik and Hannah Mischo discuss polyadenylation site recognition and what happens afterwards and how it can go wrong: Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3′ End Processing and Transcription Termination 14/ www.sciencedirect.com/science/arti...

Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3′ End Processing and Transcription Termination

Aberrant gene expression lies at the heart of many pathologies. This review will point out how 3′ end processing, the final mRNA-maturation step in th…

www.sciencedirect.com

1 3 7

Pawel Grzechnik @grzechnikpawel.bsky.social · Nov 28

some good reviews there!

Craig Kaplan @triggerloop.bsky.social · Nov 27

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...

Controlling Transcription Elongation and Termination: More Than a Means to An End

www.sciencedirect.com

2

Reposted by Pawel Grzechnik

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · Nov 25

Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️

34 240 500

Reposted by Pawel Grzechnik

Daniela Barillà @danielabarilla.bsky.social · Nov 23

📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.

Supervised by me, @Steve Quinn & @georgerheath.bsky.social

www.findaphd.com/phds/project...
Open to Applicants Worldwide!

📅 January 6, 2025

#microsky #archaeasky

Diagram showing archaeal cells containing two chromosomes bound by proteins prior to cell division.

32 33

Pawel Grzechnik @grzechnikpawel.bsky.social · Nov 23

done!

1

Pawel Grzechnik @grzechnikpawel.bsky.social · Nov 22

done

1 2

Pawel Grzechnik @grzechnikpawel.bsky.social · Nov 22

done!

1

Pawel Grzechnik @grzechnikpawel.bsky.social · Nov 22

Let’s encourage our host institutes and organizations to move to Bluesky!
Follow those already here (UK starter pack), and let me know about others who have joined!

go.bsky.app/JMrhz8Q

5 6 16

Reposted by Pawel Grzechnik

Molecular and Cellular Function, University of Manchester @mcf-uom.bsky.social · Nov 21

Hello, Bluesky community!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!

4 11