@heathmurraylab.bsky.social
Reposted
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Genome integrity relies on rapid recycling of DNA Pol III in bacteria | PNAS
DNA replication requires precise coordination between DNA unwinding and DNA synthesis.
In all domains of life, protein–protein interactions at the ...
www.pnas.org
November 20, 2025 at 4:54 PM
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Reposted
Cool work from Heath Murray's lab where they use Cas9 nickase to study how ssDNA breaks are repaired in Bacillus subtilis #MicroSky www.nature.com/articles/s41...
Rescuing the bacterial replisome at a nick requires recombinational repair and helicase reloading - Nature Communications
DNA damage can lead to cell death. Here, the authors show that a simple cut on either strand of DNA can inactivate bacterial chromosome replication. Surprisingly, only a core set of recombination prot...
www.nature.com
November 29, 2025 at 8:20 AM
Reposted
PhD opportunity in our lab - deadline passes on Dec 2nd - don’t miss out!
New opportunity to undertake a PhD in my group at the John Innes Centre - if you’re interested in plant immunity and evolution check out the link!
Understanding Host Compatibility in the Marchantia-Phytophthora System (CARELLA_J26DTP) | Doctoral Training Partnership
The fossil record demonstrates that filamentous microbes invaded ancient plant cells with intracellular hyphal structures over 450 million years ago. To this day, a rich diversity of extant land plant...
biodtp.norwichresearchpark.ac.uk
November 28, 2025 at 7:30 PM
PhD opportunity in our lab - deadline passes on Dec 2nd - don’t miss out!
Reposted
Cool work from Heath Murray's lab where they use Cas9 nickase to study how ssDNA breaks are repaired in Bacillus subtilis #MicroSky www.nature.com/articles/s41...
Rescuing the bacterial replisome at a nick requires recombinational repair and helicase reloading - Nature Communications
DNA damage can lead to cell death. Here, the authors show that a simple cut on either strand of DNA can inactivate bacterial chromosome replication. Surprisingly, only a core set of recombination prot...
www.nature.com
November 28, 2025 at 2:25 PM
Cool work from Heath Murray's lab where they use Cas9 nickase to study how ssDNA breaks are repaired in Bacillus subtilis #MicroSky www.nature.com/articles/s41...
Reposted
(𝘌. 𝘤𝘰𝘭𝘪) chromosome replicationists take note 👇 (paper edited by mike o'donnell, so you know where you are)
#MicroSky
#MicroSky
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Genome integrity relies on rapid recycling of DNA Pol III in bacteria | PNAS
DNA replication requires precise coordination between DNA unwinding and DNA synthesis.
In all domains of life, protein–protein interactions at the ...
www.pnas.org
November 27, 2025 at 7:13 PM
(𝘌. 𝘤𝘰𝘭𝘪) chromosome replicationists take note 👇 (paper edited by mike o'donnell, so you know where you are)
#MicroSky
#MicroSky
Reposted
www.nature.com/articles/s41...
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore - Nature
Thousands of centromeres were identified and tracked across two major fungal clades, showing that new centromeres spread progressively and that the kinetochore acts as a filter to determine which new ...
www.nature.com
November 27, 2025 at 6:22 PM
www.nature.com/articles/s41...
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Reposted
Two fully-funded PhD openings in my research group at the University of York.
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
A Farewell to Arms: The Trade-off Between Growth and Defence in Bacteria (York YBDTP Project) at University of York on FindAPhD.com
PhD Project - A Farewell to Arms: The Trade-off Between Growth and Defence in Bacteria (York YBDTP Project) at University of York, listed on FindAPhD.com
tiny.cc
November 27, 2025 at 5:57 PM
Two fully-funded PhD openings in my research group at the University of York.
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
If you’re excited about viromes, phage biology, Nanopore sequencing, soils and the odd bit of alpine or agricultural field sampling, we’d love to hear from you!
🌱🦠🏔️
tiny.cc/c4pv001
tiny.cc/e4pv001
Reposted
Come join us! Soon I will be advertising a postdoc vacancy in my group as part of my @erc.europa.eu AdG project 'DARK ROOTS'. Focus of the project will be on phylo- and metagenomic mining of novel prokaryotic lineages. I will soon post a link here - stay tuned, and please repost! #asgardarchaea
a man walking in a field with an umbrella
ALT: a man walking in a field with an umbrella
media.tenor.com
November 26, 2025 at 3:39 PM
Come join us! Soon I will be advertising a postdoc vacancy in my group as part of my @erc.europa.eu AdG project 'DARK ROOTS'. Focus of the project will be on phylo- and metagenomic mining of novel prokaryotic lineages. I will soon post a link here - stay tuned, and please repost! #asgardarchaea
Reposted
Pleased to share our recent article in PNAS - a collaboration with @jessicaandreani.bsky.social & Pablo Radicella, with important roles played by many members of each team.
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes | PNAS
Natural genetic transformation is a conserved mechanism of bacterial horizontal gene
transfer, which is directed entirely by the recipient cell and...
www.pnas.org
November 26, 2025 at 7:44 AM
Pleased to share our recent article in PNAS - a collaboration with @jessicaandreani.bsky.social & Pablo Radicella, with important roles played by many members of each team.
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
Reposted
We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you.
Application deadline: 24 December
www.crick.ac.uk/careers-stud...
Application deadline: 24 December
www.crick.ac.uk/careers-stud...
Postdoctoral Fellow - H Yardimci Lab
www.crick.ac.uk
November 25, 2025 at 11:55 AM
We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you.
Application deadline: 24 December
www.crick.ac.uk/careers-stud...
Application deadline: 24 December
www.crick.ac.uk/careers-stud...
Reposted
My lab is hiring postdocs! We combine AI, protein structure prediction and comparison, and high-throughput virology to study the virus-host conflict.
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
The Starting Principal Investigators at #AITHYRA the Research Institute for Biomedical Artificial Intelligence of the OeAW in Vienna invite outstanding candidates to apply for postdoctoral positions in the field of AI/ML & Life Sciences.
www.oeaw.ac.at/aithyra/post...
Please apply by 20 Nov 2025!
www.oeaw.ac.at/aithyra/post...
Please apply by 20 Nov 2025!
October 20, 2025 at 1:03 PM
My lab is hiring postdocs! We combine AI, protein structure prediction and comparison, and high-throughput virology to study the virus-host conflict.
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
Reposted
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
November 25, 2025 at 5:10 PM
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
Reposted
Research technologist position available in the Xiao lab: We are looking for a talented recent college graduate interested in learning how a single-molecule imaging lab operates to join our team. Check it out here: hiring.jhu.edu/careers?quer...
Research Technologist (Biophysics & Biological Chemistry) | Johns Hopkins University
119351 jobs in Johns Hopkins University
hiring.jhu.edu
November 25, 2025 at 2:08 PM
Research technologist position available in the Xiao lab: We are looking for a talented recent college graduate interested in learning how a single-molecule imaging lab operates to join our team. Check it out here: hiring.jhu.edu/careers?quer...
Reposted
‘Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli‘ by Drs. Nico Yehya, Christopher Bohrer, and collaborators, is now available on bioRxiv. Check it out! doi: doi.org/10.1101/2025...
Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli
Chromosomal topology and transcription are tightly coupled, yet the quantitative impact of topological constraints on transcription, supercoiling, and the potential coupling between neighboring genes ...
doi.org
November 25, 2025 at 2:04 PM
‘Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli‘ by Drs. Nico Yehya, Christopher Bohrer, and collaborators, is now available on bioRxiv. Check it out! doi: doi.org/10.1101/2025...
Reposted
Want to join the Chromatin Biophysics team? We are recruiting a postdoc!
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
Postdoc Position: Cellular Biophysics | Radboud University
Do you want to work as a Postdoc Position: Cellular Biophysics at the Faculty of Science? Check our vacancy!
www.ru.nl
November 25, 2025 at 1:06 PM
Want to join the Chromatin Biophysics team? We are recruiting a postdoc!
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
Reposted
Glad to see this out after a rather interesting review/publication process!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The SMC Hinge is a Selective Gate for Obstacle Bypass - Nature Communications
SMC complexes are ring-shaped motors that fold DNA by extruding loops, but how they navigate large DNA obstacles is unclear. Here, Liu et al., show that SMC complexes bypass obstacles by threading obs...
www.nature.com
November 25, 2025 at 2:39 PM
Glad to see this out after a rather interesting review/publication process!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Reposted
There’s just ONE WEEK left to apply to join our amazing PhD programme next year!
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
November 25, 2025 at 11:49 AM
There’s just ONE WEEK left to apply to join our amazing PhD programme next year!
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Visit our website for more information: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd DEC 2025
Reposted
An exciting PhD opportunity is available in my lab! More info about our group and research can be found here: bdaum2.wixsite.com/daumlab
Application deadline: 8th Jan 2026.
Apply here: www.exeter.ac.uk/study/pg-res...
If you are interested, get in touch!
#ArchaeaSky #CryoEM #TeamTomo
Application deadline: 8th Jan 2026.
Apply here: www.exeter.ac.uk/study/pg-res...
If you are interested, get in touch!
#ArchaeaSky #CryoEM #TeamTomo
November 24, 2025 at 3:09 PM
An exciting PhD opportunity is available in my lab! More info about our group and research can be found here: bdaum2.wixsite.com/daumlab
Application deadline: 8th Jan 2026.
Apply here: www.exeter.ac.uk/study/pg-res...
If you are interested, get in touch!
#ArchaeaSky #CryoEM #TeamTomo
Application deadline: 8th Jan 2026.
Apply here: www.exeter.ac.uk/study/pg-res...
If you are interested, get in touch!
#ArchaeaSky #CryoEM #TeamTomo
Reposted
Still reeling from the Stanford report on Brexit. Reduced GDP by up to 8% and investment by as much as 18%. The UK Treasury would have £40 billion more each year if Britain had remained in the EU. Devastating self-immolation.
The Economic Impact of Brexit
Other
siepr.stanford.edu
November 24, 2025 at 11:02 AM
Still reeling from the Stanford report on Brexit. Reduced GDP by up to 8% and investment by as much as 18%. The UK Treasury would have £40 billion more each year if Britain had remained in the EU. Devastating self-immolation.
Reposted
There’ll be several opportunities to join the group, starting w/ a PhD studentship via the BBSRC-NRP Doctoral Training Partnership.
Team up w/ us, @saskiahogenhout.bsky.social & @berasymbionts.bsky.social to answer how microbes shape insect behavior:
biodtp.norwichresearchpark.ac.uk/projects/mic...
Team up w/ us, @saskiahogenhout.bsky.social & @berasymbionts.bsky.social to answer how microbes shape insect behavior:
biodtp.norwichresearchpark.ac.uk/projects/mic...
Microbial determinants of behaviour in herbivorous beetles (SALEM_J26DTP) | Doctoral Training Partnership
Many animals rely on beneficial microbes for nutrition, defence, or reproduction. In this project, the student will explore an exciting new dimension of these relationships:
biodtp.norwichresearchpark.ac.uk
November 24, 2025 at 6:42 PM
There’ll be several opportunities to join the group, starting w/ a PhD studentship via the BBSRC-NRP Doctoral Training Partnership.
Team up w/ us, @saskiahogenhout.bsky.social & @berasymbionts.bsky.social to answer how microbes shape insect behavior:
biodtp.norwichresearchpark.ac.uk/projects/mic...
Team up w/ us, @saskiahogenhout.bsky.social & @berasymbionts.bsky.social to answer how microbes shape insect behavior:
biodtp.norwichresearchpark.ac.uk/projects/mic...
Reposted
🆕 Vacancy! We are looking for an exceptional scientist with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme.
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
November 24, 2025 at 10:00 AM
🆕 Vacancy! We are looking for an exceptional scientist with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme.
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
Reposted
Now properly published at @natcomms.nature.com with few additional experiments incl. demonstration of Daptomycin's ability to depolarise non-growing cells.
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky
November 24, 2025 at 8:20 PM
Now properly published at @natcomms.nature.com with few additional experiments incl. demonstration of Daptomycin's ability to depolarise non-growing cells.
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky
Reposted
Excellent opportunity for an enthusiastic person to join the LMB, providing administrative assistance to scientists in our Structural Studies Division across a diverse range of topics.
More info: www.jobs.ac.uk/job/DPM745/a...
Closes 02 DEC
#CambridgeJobs
More info: www.jobs.ac.uk/job/DPM745/a...
Closes 02 DEC
#CambridgeJobs
November 24, 2025 at 2:59 PM
Excellent opportunity for an enthusiastic person to join the LMB, providing administrative assistance to scientists in our Structural Studies Division across a diverse range of topics.
More info: www.jobs.ac.uk/job/DPM745/a...
Closes 02 DEC
#CambridgeJobs
More info: www.jobs.ac.uk/job/DPM745/a...
Closes 02 DEC
#CambridgeJobs
Reposted
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
November 21, 2025 at 6:18 PM
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough