Preston Wiles
@hombredebicycle.bsky.social
MD, psychiatrist, former cyclist, rabid Episcopalian
Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...
Single-cell alternative polyadenylation analysis reveals mechanistic insights of COVID-19-associated neurological and psychiatric effects
COVID-19 is associated with increased risks of neurological and psychiatric sequelae. Alternative polyadenylation (APA) is ubiquitous in human genes, resulting in mRNA diversity, and has been validate...
dx.plos.org
December 29, 2025 at 3:11 PM
Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...
Stimulant medications affect arousal and reward, not attention networks: Cell www.cell.com/cell/fulltex...
Stimulant medications affect arousal and reward, not attention networks
Stimulant medications (e.g., methylphenidate) were thought to improve attention by
acting on the brain's attention networks. Functional connectivity data now reveal
that stimulants are associated with...
www.cell.com
December 27, 2025 at 6:58 PM
Stimulant medications affect arousal and reward, not attention networks: Cell www.cell.com/cell/fulltex...
Author points to Trump's early venture as 'the smoking gun' on Epstein ties
www.rawstory.com/jeffrey-epst...
www.rawstory.com/jeffrey-epst...
Author points to Trump's early venture as 'the smoking gun' on Epstein ties
Author and public speaker Steve Siebold made an explosive claim Thursday about President Donald Trump and his ties to Jeffrey Epstein, alleging that a “smoking gun” may be buried in the history of bea...
www.rawstory.com
December 27, 2025 at 2:39 PM
Author points to Trump's early venture as 'the smoking gun' on Epstein ties
www.rawstory.com/jeffrey-epst...
www.rawstory.com/jeffrey-epst...
Reposted by Preston Wiles
O come, Desire of nations, bind
In one the hearts of all mankind;
Bid Thou our sad divisions cease,
And be Thyself our king of Peace.
In one the hearts of all mankind;
Bid Thou our sad divisions cease,
And be Thyself our king of Peace.
December 22, 2025 at 11:10 PM
O come, Desire of nations, bind
In one the hearts of all mankind;
Bid Thou our sad divisions cease,
And be Thyself our king of Peace.
In one the hearts of all mankind;
Bid Thou our sad divisions cease,
And be Thyself our king of Peace.
Reposted by Preston Wiles
“His Excellency President LINCOLN:
I beg to present you, as a Christmas gift, the city of Savannah, with 150 heavy guns and plenty of ammunition, and also about 25,000 bales of cotton.”
Major General William T. Sherman, December 22, 1864
I beg to present you, as a Christmas gift, the city of Savannah, with 150 heavy guns and plenty of ammunition, and also about 25,000 bales of cotton.”
Major General William T. Sherman, December 22, 1864
December 22, 2025 at 11:11 PM
“His Excellency President LINCOLN:
I beg to present you, as a Christmas gift, the city of Savannah, with 150 heavy guns and plenty of ammunition, and also about 25,000 bales of cotton.”
Major General William T. Sherman, December 22, 1864
I beg to present you, as a Christmas gift, the city of Savannah, with 150 heavy guns and plenty of ammunition, and also about 25,000 bales of cotton.”
Major General William T. Sherman, December 22, 1864
Why can no one STOPTHIS?!?
ICE agents illegally break into a woman's bathroom in a NY nutrition bar manufacturing plant. "Pull up your pants," says a male agent. The agents only had a warrant to review employer documents. They didn't have a warrant to search for, detain, or arrest anyone there.
December 22, 2025 at 10:26 PM
Why can no one STOPTHIS?!?
Reposted by Preston Wiles
ICE agents illegally break into a woman's bathroom in a NY nutrition bar manufacturing plant. "Pull up your pants," says a male agent. The agents only had a warrant to review employer documents. They didn't have a warrant to search for, detain, or arrest anyone there.
December 22, 2025 at 7:52 PM
ICE agents illegally break into a woman's bathroom in a NY nutrition bar manufacturing plant. "Pull up your pants," says a male agent. The agents only had a warrant to review employer documents. They didn't have a warrant to search for, detain, or arrest anyone there.
Reposted by Preston Wiles
He’s gilded the entire White House, slapped his name on both the Kennedy Center and Institute for Peace, installed a new Trump Gold Card, and now proposing a new “Trump class” of naval vessels.
I know we keep saying this is insane but this is seriously fucking insane.
I know we keep saying this is insane but this is seriously fucking insane.
oh my god its literally Long Beach's wario
December 22, 2025 at 10:20 PM
He’s gilded the entire White House, slapped his name on both the Kennedy Center and Institute for Peace, installed a new Trump Gold Card, and now proposing a new “Trump class” of naval vessels.
I know we keep saying this is insane but this is seriously fucking insane.
I know we keep saying this is insane but this is seriously fucking insane.
Long COVID: a long road ahead url: academic.oup.com/ooim/article...
Long COVID: a long road ahead
Abstract. The SARS-CoV-2 pandemic caused an estimated 400 million people worldwide to experience Long COVID and post-COVID complications leading to signifi
academic.oup.com
December 22, 2025 at 2:36 PM
Long COVID: a long road ahead url: academic.oup.com/ooim/article...
Pathways of pain | Science www.science.org/doi/10.1126/...
Pathways of pain
Estrogen tunes a cross-talk between hormone-secreting cells in the mouse gut to regulate visceral pain
www.science.org
December 21, 2025 at 1:57 PM
Pathways of pain | Science www.science.org/doi/10.1126/...
Recent discoveries on the acquisition of the highest levels of human performance | Science www.science.org/doi/10.1126/...
Recent discoveries on the acquisition of the highest levels of human performance
Scientists have long debated the origins of exceptional human achievements. This literature review summarizes recent evidence from multiple domains on the acquisition of world-class performance. We re...
www.science.org
December 20, 2025 at 8:13 PM
Recent discoveries on the acquisition of the highest levels of human performance | Science www.science.org/doi/10.1126/...
Reposted by Preston Wiles
J. D. Vance believes that immigrants are the prime driver of American anti-Semitism—but making anti-Semitism about your ideological enemies misses whole dimensions of the problem, @yair-rosenberg.bsky.social argues:
What J. D. Vance—And Many Others—Miss About American Anti-Semitism
Making anti-Semitism about your ideological enemies doesn’t help anyone understand, let alone solve, the problem.
bit.ly
December 19, 2025 at 9:01 PM
J. D. Vance believes that immigrants are the prime driver of American anti-Semitism—but making anti-Semitism about your ideological enemies misses whole dimensions of the problem, @yair-rosenberg.bsky.social argues:
Reposted by Preston Wiles
🚨BREAKING: The Department of Justice will fail to publicly release all of its files on convicted sex offender Jeffrey Epstein by a Friday deadline, violating a new federal law explicitly mandating that the trove of documents be turned over for public scrutiny. www.democracydocket.com/news-alerts/...
DOJ Chickens Out on Epstein Files Release in Violation of New Law
Read more here.
www.democracydocket.com
December 19, 2025 at 6:29 PM
🚨BREAKING: The Department of Justice will fail to publicly release all of its files on convicted sex offender Jeffrey Epstein by a Friday deadline, violating a new federal law explicitly mandating that the trove of documents be turned over for public scrutiny. www.democracydocket.com/news-alerts/...
Watching Providence retreat into itself after the Brown shooting www.motherjones.com/politics/202...
Watching Providence retreat into itself after the Brown shooting
What it's like when this uniquely American horror arrives in your city.
www.motherjones.com
December 17, 2025 at 7:50 PM
Watching Providence retreat into itself after the Brown shooting www.motherjones.com/politics/202...
Pandemic security needs national leadership | Science www.science.org/doi/10.1126/...
Pandemic security needs national leadership
In a world facing escalating risks from conflict, climate change, and emerging infectious diseases, health systems are the first line of defense for protecting people, economies, and stability. Althou...
www.science.org
December 13, 2025 at 3:15 PM
Pandemic security needs national leadership | Science www.science.org/doi/10.1126/...
Harvard Replaces Leader of Health Center Said to Have Focused on Palestinians www.nytimes.com/2025/12/12/u...
Harvard Replaces Leader of Health Center Said to Have Focused on Palestinians
www.nytimes.com
December 13, 2025 at 2:32 PM
Harvard Replaces Leader of Health Center Said to Have Focused on Palestinians www.nytimes.com/2025/12/12/u...
Rise of anti-science rhetoric has fundamentally changed the relationship between doctors and patients www.statnews.com/2025/12/10/a... via @statnews.com
Rise of anti-science rhetoric has fundamentally changed the relationship between doctors and patients
“The rise of anti-science and anti-vaccine rhetoric has fundamentally changed the relationship between clinicians and patients.”
www.statnews.com
December 11, 2025 at 6:20 PM
Rise of anti-science rhetoric has fundamentally changed the relationship between doctors and patients www.statnews.com/2025/12/10/a... via @statnews.com
Long COVID Incidence Proportion in Adults and Children Between 2020 and 2024: An Electronic Health Record-Based Study From the RECOVER Initiative url: academic.oup.com/cid/article-...
Long COVID Incidence Proportion in Adults and Children Between 2020 and 2024: An Electronic Health Record-Based Study From the RECOVER Initiative
This electronic health record–based study of COVID-19–positive patients across 3 national research networks found consistent temporal patterns in incidence
academic.oup.com
December 11, 2025 at 3:13 PM
Long COVID Incidence Proportion in Adults and Children Between 2020 and 2024: An Electronic Health Record-Based Study From the RECOVER Initiative url: academic.oup.com/cid/article-...
H5N1’s tipping point: Scientists identify when containment fails www.nature.com/articles/d44...
H5N1’s tipping point: Scientists identify when containment fails
India’s patchy bird monitoring across wetlands-farm interfaces risks overlooking the virus until it’s too late.
www.nature.com
December 10, 2025 at 10:58 PM
H5N1’s tipping point: Scientists identify when containment fails www.nature.com/articles/d44...
Reposted by Preston Wiles
Recommended read: In the @theguardian.com George Monbiot lamented the rise of investor-state dispute settlements, which he described as “undemocratic offshore tribunals” that are already having a “chilling effect” on countries’ climate ambitions.
Hello, foreign oligarchs and corporations! Please come and sue the UK for billions | George Monbiot
The case of a planned Cumbrian coalmine shows how governments around the world are being threatened by litigation in shadowy offshore courts, says Guardian columnist George Monbiot
buff.ly
December 7, 2025 at 2:49 PM
Recommended read: In the @theguardian.com George Monbiot lamented the rise of investor-state dispute settlements, which he described as “undemocratic offshore tribunals” that are already having a “chilling effect” on countries’ climate ambitions.
The lingering shadow of epidemics: post-acute sequelae across history: Trends in Immunology www.cell.com/trends/immun...
The lingering shadow of epidemics: post-acute sequelae across history
The SARS-CoV-2 pandemic has drawn global attention to post-acute infection syndromes
(PAIS), with millions affected by post-acute sequelae of COVID-19 (PASC, or Long COVID).
While Long COVID is newly ...
www.cell.com
December 5, 2025 at 7:08 PM
The lingering shadow of epidemics: post-acute sequelae across history: Trends in Immunology www.cell.com/trends/immun...
The ‘Useful Idiots’ From America Whom Putin Is Playing Like a Flute www.nytimes.com/2025/12/04/o...
Opinion | The ‘Useful Idiots’ From America Whom Putin Is Playing Like a Flute
www.nytimes.com
December 5, 2025 at 6:24 PM
The ‘Useful Idiots’ From America Whom Putin Is Playing Like a Flute www.nytimes.com/2025/12/04/o...
Republican Anger Erupts at Johnson as Party Frets About Future www.nytimes.com/2025/12/03/u...
Republican Anger Erupts at Johnson as Party Frets About Future
www.nytimes.com
December 3, 2025 at 11:00 PM
Republican Anger Erupts at Johnson as Party Frets About Future www.nytimes.com/2025/12/03/u...
Reposted by Preston Wiles
🚨 NEW: A majority of Americans now support Medicare for All even if it ends private insurance and raises taxes. The tipping point is here because the ACA is failing to keep health care affordable. New polling shows a 50-point shift in just six years.
December 3, 2025 at 10:46 PM
🚨 NEW: A majority of Americans now support Medicare for All even if it ends private insurance and raises taxes. The tipping point is here because the ACA is failing to keep health care affordable. New polling shows a 50-point shift in just six years.
Third unvaccinated Kentucky baby dies of whooping cough kentuckylantern.com/2025/11/25/t...
Third unvaccinated Kentucky baby dies of whooping cough • Kentucky Lantern
A third unvaccinated infant in Kentucky has died of pertussis as public health officials urge Kentuckians to get vaccinated against the disease.
kentuckylantern.com
December 1, 2025 at 2:38 PM
Third unvaccinated Kentucky baby dies of whooping cough kentuckylantern.com/2025/11/25/t...