Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f

Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience

➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?

Check out what we found!
🧵1/n

Now out in @natneuro.nature.com

What happens to the brain’s body map when a body-part is removed?

Scanning patients before and up to 5 yrs after arm amputation, we discovered the brain’s body map is strikingly preserved despite amputation

www.nature.com/articles/s41593-025-02037-7

🧵1/18

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

🎓 My team is seeking a PhD student in Biochemistry & Cell Biology at I2BC, Paris-Saclay!
🔬 Study cytoskeletal signaling in collective cell migration
🌍 Fully funded, 3 yrs | 📍 Gif-sur-Yvette, France
🗓️ Apply by Aug 22 via the following link:
emploi.cnrs.fr/Offres/Docto...

Interested in cortical malformations 🧠 and #epilepsy?
We will soon have 2 open positions:
- early career postdoc with experience in slice & in vivo electrophysiology
- research engineer with experience in bioinformatics and data analysis
Please get in touch (DM) if interested.
Please repost!

Excited to share this huge team effort collaboration supervised by Stephanie Page in Translational Neuroscience @lieberinstitute.bsky.social and @stephaniehicks.bsky.social @jhubiostat.bsky.social to generate a spatio-molecular resource of the hippocampus in human 🧠

www.nature.com/articles/s41...

🧠 Opportunity for a post-doctoral position on human neurobiology, funded by the @erc.europa.eu!
🧫You want to use human pluripotent stem cell based models to understand the evolution of human cerebellar neurons and disorders, this position is for you!
🔗Apply here: emploi.cnrs.fr/Offres/CDD/U...

Première Journée de Neurosciences Translationnelles sur l’Épilepsie à Marseille 🧠
Cliniciens, chercheurs et ingénieurs réunis pour échanger sur la génétique, les biomarqueurs et les nouvelles approches thérapeutiques.
📄 Lire l’article complet : fr.ap-hm.fr/site/maladie...

#JNeurosci: <a href="https://bsky.app/profile/did:plc:tew5jhl2vvoqzvmdop3iwlqx" class="hover:underline text-blue-600 dark:text-sky-400" target="_blank" rel="noopener">@srirams433.bsky.social‬ Guzman-Clavel et al. uncover roles for Mef2c in cortical development: regulation of laminar subtype specification during embryogenesis & axon targeting in postnatal callosal neurons. @oneneuroinitiative.bsky.social
https://doi.org/10.1523/JNEUROSCI.0201-25.2025

1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

Our new preprint is out 🤩!
Proud to share our work uncovering the molecular diversity and developmental origins of cerebellar astrocytes. A deep dive into cerebellar gliogenesis using scRna-seq and lineage-tracing approaches. Big thanks @Valentina_Cerr @BuffoLab giacomo Turrini.

🔬 New preprint out!

Thrilled to share our new preprint, where we uncover the molecular diversity and developmental origins of cerebellar astrocytes using multi-omic approaches.

📄 www.biorxiv.org/content/10.1...

#scRNAseq #astrocytes #neuroscience #glia #cerebellum @biorxiv-neursci.bsky.social

Excited to share David Hirst's PhD work!
🧬 When you only have a few datasets available for multi-omics integration, for instance because you work on rare diseases, one solution is Transfer Learning. Introducing #MOTL - now available in Genome Biology!

doi.org/10.1186/s130...

Newborn brains already show individual patterns of functional organization. 🧠✨

Using #fMRI for precision mapping, researchers at @washumedicine.bsky.social found that each baby's brain has a unique layout—already present just after birth.

www.biorxiv.org/content/10.1...

#neuroskyence #MRI 🧪

Two papers in today's issue of @nature.com ‬: 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

Hey, it's out!
doi.org/10.1016/j.ce... Aligning Big Brains and Atlases, ABBA in short, is published in Cell Reports @cp-cellreports.bsky.social . @biancasilvalab.bsky.social's lab added an analysis pipeline on top of it (BraiAn) and did all the relevant biological work. What is it ? Short thread:

ER_2025 #endoplasmicreticulum #ER #conference Paris October 8-10 2025 Register! itbcrde.inserm.fr/index.php?page…

Neural models for detection and classification of brain states and transitions
www.nature.com/articles/s42...
#neuroscience

1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵

www.biorxiv.org/content/10.1...

Dear @jbmanent.bsky.social, our son has had 5 seizures. He's stopped breathing, his lips turning blue. We were terrified. We turned that fear into a book to help raise awareness — Ivan’s Seizure Helpers. It’s now a Kickstarter 💜 Please support and help amplify! kickstarter.com/projects/iva...

On a besoin d’un petit coup de main 💬
On recrute des infirmier·ères en psychiatrie pour nos équipes à l’Hôpital de la Conception, à Marseille.
Un partage, un relais, un mot : ça peut vraiment aider.
Merci à celles et ceux qui feront passer le message 💙

Please join the Next GDR Organoids webinar this Friday!!! June 27th from 1:00 PM to 2:00 PM (CET).
Dr Michael L. Shuler, Professor Emeritus @cornelluniversity.bsky.social will present his work on Body-on-a-Chip zoom : univ-lille-fr.zoom.us/j/9841896627... @cnrs.fr @inserm.fr

🎥 REPLAY DISPONIBLE – Symposium franco-belge « Les mille premiers jours de la vie » du 18 juin 2025

Retrouverez le replay de cette journée d’échanges scientifiques ici : autisme-neurodev.org/evenements/2...