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Christophe Le Clainche @actin-paris-saclay.bsky.social · 26d

This week we are celebrating the 10th anniversary of the I2BC — very proud of what we have accomplished together! www.i2bc.paris-saclay.fr

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Aug 6

🎓 My team is seeking a PhD student in Biochemistry & Cell Biology at I2BC, Paris-Saclay!
🔬 Study cytoskeletal signaling in collective cell migration
🌍 Fully funded, 3 yrs | 📍 Gif-sur-Yvette, France
🗓️ Apply by Aug 22 via the following link:
emploi.cnrs.fr/Offres/Docto...

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Reposted by Christophe Le Clainche

Kat Toropova @kattoropova.bsky.social · Apr 30

Postdoc position in my lab: investigating how the microtubule motor protein dynein-2 works in cilia.

Here's dynein-2 at work translocating microtubules - how is this activity regulated? How does dynein-2 malfunction in disease?

Find out more and apply:
my.corehr.com/pls/uoxrecru...

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Reposted by Christophe Le Clainche

Robert Arkowitz @robertarkowitz.bsky.social · Apr 5

Genetically encoded reporters of actin filament organization in living cells and tissues: Cell www.cell.com/cell/fulltex...

Genetically encoded reporters of actin filament organization in living cells and tissues

Tailoring genetic fusions of widely used actin localization reporters by constraining the mobility of the fluorescent proteins allows measurements of actin filament organization in living cells and ti...

www.cell.com

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Reposted by Christophe Le Clainche

Florence Niedergang @florenceniedergang.bsky.social · Mar 28

Our latest publication on #macrophages congrats Anna Mularski and @manondepierre.bsky.social @institutcochin.bsky.social @actin-paris-saclay.bsky.social Martial Balland @grenoblealpes.bsky.social
@cnrsbiologie.bsky.social cnrs physique @anr

CNRS Biologie @cnrsbiologie.bsky.social · Mar 28

Comment les macrophages sont influencés par leur environnement ? 🧐
Une récente étude menée par @florenceniedergang.bsky.social révèle que leur interaction avec leur milieu joue un rôle clé dans leur activité immunitaire !

L’interaction entre les macrophages et leur milieu environnant affecte leur fonctionnement

Les macrophages sont des cellules du système immunitaire qui ingèrent et dégradent les microorganismes et les débris cellulaires selon un processus appe

buff.ly

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Reposted by Christophe Le Clainche

Institut Jacques Monod @ijmonod.bsky.social · Mar 24

✍️ The @bladoux.bsky.social / @rmmege.bsky.social Lab published a new article

📖 Nature materials
📃 Force transmission is a master regulator of mechanical cell competition
🔗 www.nature.com/articles/s41...

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Reposted by Christophe Le Clainche

Benoit Ladoux @bladoux.bsky.social · Mar 14

Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...

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Reposted by Christophe Le Clainche

Journal of Cell Biology @jcb.org · Mar 21

In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...

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Reposted by Christophe Le Clainche

Journal of Cell Biology @jcb.org · Feb 12

Our new #Mechanobiology collection examines the mechanical properties & interactions that shape the fundamental operations & structures of cells. Delve into diverse mechanical properties of membranes, organelles & other structures within & among cells 👉 https://buff.ly/3EK0uaq

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Mar 15

Congratulations to all !
Very happy to have been part of this collaboration !

Florence Niedergang @florenceniedergang.bsky.social · Mar 15

our lastest publication on #macrophages and #phagocytosis
@institutcochin.bsky.social
is out! thanks to
@manondepierre.bsky.social
and Anna Mularski in colaboration with
@actin-paris-saclay.bsky.social
and Martial Balland
@ugrenoblealpes.bsky.social

Institut Cochin @institutcochin.bsky.social · Mar 14

Publication in iSciences: the team led by @florenceniedergang.bsky.social shows the existence of a crosstalk between adhesion to the substrate and phagocytosis in #macrophages.
institutcochin.fr/en/crosstalk...
@cnrsbiologie.bsky.social @cnrs-idf-villejuif.bsky.social @inserm.fr @upcite.bsky.social

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Reposted by Christophe Le Clainche

Manuel Thery @manuelthery.bsky.social · Mar 5

Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost 🙏 thanks !

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Feb 24

Don't miss the opportunity to come and work with us, as this is the last week to apply for our cell biology group leader position.

Application deadline: Feb 28, 2025

Christophe Le Clainche @actin-paris-saclay.bsky.social · Jan 27

The Institute for Integrative Biology of the Cell (I2BC) is recruiting group leaders in cell biology.

Don't miss the opportunity to start your team in the vibrant environment of Paris-Saclay University.

Application deadline: Feb 28, 2025

www.i2bc.paris-saclay.fr @i2bcparissaclay.bsky.social

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Serini Lab @adhynamic.bsky.social · Feb 23

Glad to share our last manuscript on a luminescent sensor we created to unveil novel potentially actionable regulators of β1 integrin activation in vascular endothelial cells and angiogenesis. @cp-cellreports.bsky.social www.cell.com/cell-reports...

• β1 integrin activation sensor (β1IAS) reports β1 integrin activation in response to biochemical and physical stimuli

• siRNA HTS on β1IAS KI endothelial cells unveils unknown regulators of β1 integrin activation

• E3 ubiquitin ligase Pja2 promotes kindlin-2 degradation and inhibits β1 integrin activation

• VEGF-B is a so far unrecognized effective inhibitor of β1 integrin activation

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Reposted by Christophe Le Clainche

lab-scita.bsky.social @lab-scita.bsky.social · Feb 1

Deeply saddened by the passing of Prof. Mike Sheetz, a true leader in Mechanobiology. His groundbreaking work on Kinesin, membrane organization, and mechanotransduction has left an indelible mark. A tremendous loss to science. #Mechanobiology #Science #LaskerAward

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Jan 27

The Institute for Integrative Biology of the Cell (I2BC) is recruiting group leaders in cell biology.

Don't miss the opportunity to start your team in the vibrant environment of Paris-Saclay University.

Application deadline: Feb 28, 2025

www.i2bc.paris-saclay.fr @i2bcparissaclay.bsky.social

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Uri Manor @manorlaboratory.bsky.social · Jan 7

Our collaboration with the Germain Lab is now out in its final form!

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mehmet can uçar @mehmetcanucar.bsky.social · Dec 2

📣 I’m looking for PhD students to work at the intersection of theoretical physics & biology -topics range from active cell mechanics to collective cell migration & tissue patterning!

Feel free to reach out for more info (DM/email)!

Please repost / share 🙂

PhD positions available at the intersection of theoretical physics & biology (contact: m.c.ucar@sheffield.ac.uk )

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Dec 5

OFFRE D'EMPLOI / JOB OFFER (IN FRENCH)

Notre équipe peut accueillir un-e assistant-e ingénieur-e en biologie (déjà en poste au CNRS) dans le cadre du programme NOEMI de mobilité interne du CNRS.

Pour candidater et obtenir plus d’informations : bit.ly/4gjpFhQ

Détails de la fonction choisie

bit.ly

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Stephane Vassilopoulos @stefvass.bsky.social · Dec 3

Clathrin-coated pits, plaques, and adhesion... This post is dedicated to Christien Merrifield, who left us far too soon around this time in 2017. His memory continues to inspire 🔬
doi.org/10.1016/j.js...

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Dec 3

Christien has inspired a great deal of work on endocytosis and the cytoskeleton. He was one of my scientific reference when I was a postdoc. Later, I was lucky enough to be his lab neighbor in France before his tragic death. I remember him as a highly creative and passionate scientist. We miss him.

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Carsten Schulte @carstenschulte4.bsky.social · Nov 21

I didn't find a specific mechanotransduction starter pack, so I open one myself😊. There are still a lot of people to be added, but it's late, so please drop me a message or post here to nominate yourself for the Mechanotransduction community.

go.bsky.app/2PXf5SC

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Nov 21

Great idea, please add me to the list !

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Christophe Le Clainche @actin-paris-saclay.bsky.social · Nov 18

Our lab is delighted to welcome Arthur Molines, whose project to understand the influence of the physical properties of the cytoplasm on the dynamics and organization of cytoskeletons in cells is extremely promising. Thank you Arthur for choosing our lab and welcome to I2BC !

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A. T. Molines @atmolines.bsky.social · Nov 18

Recently, I joined @actin-paris-saclay.bsky.social team as an Assoc. Prof. 🎉
There I will continue to explore the feedback between the physics of the cytoplasm and cytoskeleton dynamics using in cellulo and in vitro approaches.

I am looking forward to interacting with you all here.

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Reposted by Christophe Le Clainche

Olivier Namy 🧬🧪 @onamy.bsky.social · Nov 17

go.bsky.app/Kjf7vCa

I made this starter pack for #I2BC members. If you are not on the list, sorry. Please contact me I will add you 😉 (corrected)

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