Jordan Zhou
@jordan-zhou.bsky.social
1K followers 770 following 36 posts
Postdoc/NIDDK F32 - Sonnenberg Lab (Weill Cornell Medicine). Neuroimmune/ILCs/Barrier Immunity/GI/Cancer Immunology
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jordan-zhou.bsky.social
6/6 From what I've seen, many institutions have also noticed this shift and are focusing resources on these technological developments for the sake of developing treatments and undertaking research that is heavily transnational in lieu of basic science.
jordan-zhou.bsky.social
5/6 So what will future Nobels look like? It seems to me that, eventually, the age of discovery will end and be replaced with an age of innovation in which much of the most impactful research will be focused on the development of new technologies rather than discovery of a new protein or cell type
jordan-zhou.bsky.social
4/6 In addition, we now integrate multiple systems within each research project (e.g. neuro-immune, cancer-metabolism, cancer-immunology, etc.) and are studying interactions between cell types and, again, context-dependent functions, which do not generally get awarded the Nobel.
jordan-zhou.bsky.social
3/6 With the current methodologies, much of the research is focused on determining how different cell states and context-dependent functions of cells impact health, but these types of discoveries, although important, do not usually lead to paradigm shifting advances in the field warranting the Nobel
jordan-zhou.bsky.social
2/6 Today, with the spread of omics technologies, we have essentially already established what cells exist and have an idea of their overall functions. We will no longer be able to look at a disease, or a classification of diseases, and pin the blame on a new cell type. Problems are more complex.
jordan-zhou.bsky.social
1/6 With recent excitement around the #NobelPrize announcements, I think it's worth thinking about what the prize will look like in the future, especially for physiology and medicine. What happens when there’s nothing left to discover in medicine? Have we already picked the low-hanging fruit?
jordan-zhou.bsky.social
The fact that public funds are used to publish publicly funded research in journals owned by private publishers, who then sell access to that research at ridiculous prices to entities that buy it with more public funds, is kind of insane.
Reposted by Jordan Zhou
jbendery.bsky.social
"The U.S. Department of Health and Human Services (HHS) today announced the beginning of a coordinated wind-down of its mRNA vaccine development activities...."

cc: Sen. Bill Cassidy
Reposted by Jordan Zhou
maitreya.bsky.social
Genome Sciences is looking for a Director of Departmental Computing. This is a rare opportunity for someone interested in leading our excellent IT team, building and maintaining computational infrastructure, and working closely with our faculty and labs uwhires.admin.washington.edu/ENG/candidat...
UW Human Resources
University of Washington Human Resources
uwhires.admin.washington.edu
Reposted by Jordan Zhou
labwaggoner.bsky.social
Utility of transgenic hematopoietic stem cell to generate a self-renewing source of tumor-specific cellular immunotherapy in human participants @natcomms.nature.com
www.nature.com/articles/s41...
Reposted by Jordan Zhou
patrickveiga.bsky.social
Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz Mélanie Deschasaux Rebekka Lambrecht rdcu.be/epret
The gut microbiome connects nutrition and human health
Nature Reviews Gastroenterology & Hepatology - In this Review, Sanz and colleagues discuss how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune,...
rdcu.be
Reposted by Jordan Zhou
cyrilpedia.bsky.social
'However, we now report that food-specific pTreg cells are exclusively induced by the recently identified RORγt APCs4–8 and not by cDCs. Instead, our data suggest that pTreg–cDC1 interactions in steady-state limit the expansion of food-specific CD8αβ T cells.'
www.nature.com/articles/s41...
A coordinated cellular network regulates tolerance to food - Nature
Nature - A coordinated cellular network regulates tolerance to food
www.nature.com
Reposted by Jordan Zhou
deniswirtz.bsky.social
50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science.

Scientific discoveries and training of our next generation of scientists and engineers are halved.

How is that helping the US?
Reposted by Jordan Zhou
amjtransplant.bsky.social
Article in Press AND Open Access! "Cell therapy with human IL-10-producing ILC2s enhances islet function and inhibits allograft rejection" by Colpitts et al. doi.org/10.1016/j.aj... @sarahcolpitts.bsky.social @sarahcrome.bsky.social #celltherapy #islettransplantation
Reposted by Jordan Zhou