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Kyogo Kawaguchi @kyogok.bsky.social · Sep 8

Call for a research scientist position (indefinite-term) in our group. Deadline: October 15
www.riken.jp/en/careers/r...

Seeking a Research Scientist (Indefinite-term) at Nonequilibrium Physics of Living Matter Laboratory (25-1294)

www.riken.jp

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Kyogo Kawaguchi @kyogok.bsky.social · Jun 5

Exciting new study from Iwasaki lab, led by Kotaro @ktomuro.bsky.social & Yuichi @u1-7no.bsky.social, that I was lucky to be part of! A new method reveals many mRNAs are locally translated. Too much for one tweet—check it out: www.biorxiv.org/content/10.1...

www.biorxiv.org

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Reposted by Kyogo Kawaguchi

Kotaro TOMURO @ktomuro.bsky.social · May 30

We developed APEX-Ribo-Seq, a method to map subcellular translation with spatial resolution.
Using it, we profiled local translation in over 20 conditions!

bioRxivpreprint @biorxivpreprint.bsky.social · May 30

Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq https://www.biorxiv.org/content/10.1101/2025.05.26.656194v1

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Kyogo Kawaguchi @kyogok.bsky.social · May 23

Call for RIKEN ECL Team / Unit Leaders. In my (biased) opinion, this is probably the best option if you are seeking an independent position in Japan. I will be happy to chat/answer questions via email. www.riken.jp/en/careers/p...

FY 2025 Call for RIKEN ECL Team / Unit Leaders

www.riken.jp

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Kyogo Kawaguchi @kyogok.bsky.social · May 20

www.riken.jp/en/careers/p...

FY 2025 Call for RIKEN ECL Team / Unit Leaders

www.riken.jp

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Kyogo Kawaguchi @kyogok.bsky.social · May 15

This is a bizarre discovery by Kyosuke. He introduces an active binary mixture model and finds bubbles, typically found in very large MIPS simulations, appearing in smaller setups. Then observes that even the mean-field deterministic ver. of the model also produces bubbles.
arxiv.org/abs/2505.08637

Bubble formation in active binary mixture model

Phase separation, the spontaneous segregation of density, is a ubiquitous phenomenon observed across diverse physical and biological systems. Within a crowd of self-propelled elements, active phase se...

arxiv.org

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Kyogo Kawaguchi @kyogok.bsky.social · Mar 28

Congrats to our colleague Takahiro Kanazawa, who graduated with honors from U Tokyo Physics! www.s.u-tokyo.ac.jp/ja/info/10714/

令和6年度総長賞・学修奨励賞・研究奨励賞 - 東京大学大学院理学系研究科・理学部

東京大学大学院理学系研究科・理学部の令和6年度総長賞・学修奨励賞・研究奨励賞情報です。

www.s.u-tokyo.ac.jp

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Kyogo Kawaguchi @kyogok.bsky.social · Mar 20

RIKEN SPDR fellowship, Register basic information by 5 pm April 3, 2025 (Japan Time). Application deadline 5 pm April 10, 2025 (Japan Time).

Feel free to contact regarding this, or about opportunities in RIKEN and Japan in general.

Kyogo Kawaguchi @kyogok.bsky.social · Feb 4

We can host Special Postdoctoral Researchers (SPDR) for FY 2026. This is one of the best postdoc positions you can find in Japan, comparable to departmental or institutional fellowships in the US or Europe. Feel free to reach out if you’re interested!
www.riken.jp/en/careers/p...

Call for applications for the position of Special Postdoctoral Researcher (SPDR) for FY 2026

www.riken.jp

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Reposted by Kyogo Kawaguchi

Rosana Collepardo @rcollepardo.bsky.social · Jan 23

What is the multiscale structure of chromatin condensates? How does it shape thermodynamic and material properties?

We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)

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Kyogo Kawaguchi @kyogok.bsky.social · Mar 13

Congratulations to Zihui, Sano-san, and the team on this interesting work! They found that +1 topological defects attract neural progenitors—an observation that seems at odds with expectations for an extensile active nematic. www.nature.com/articles/s41...

Integer topological defects offer a methodology to quantify and classify active cell monolayers - Nature Communications

The orientation of elongated cells often rotates once around the center in tissue. Such structures are called +1 topological defects and play some roles in biological development. By inducing various ...

www.nature.com

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Reposted by Kyogo Kawaguchi

Surya Ganguli @suryaganguli.bsky.social · Feb 7

My @TEDAI2024 talk is out!
www.ted.com/talks/surya_...
I discuss our work, spanning AI, physics, math & neuroscience, to develop a deeper scientific understanding of intelligence, both to understand biological intelligence and make better artificial intelligence. I focus on 5 gaps:

Can AI match the human brain?

AI is evolving into a mysterious new form of intelligence — powerful yet flawed, capable of remarkable feats but still far from human-like reasoning and efficiency. To truly understand it and unlock i...

www.ted.com

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Reposted by Kyogo Kawaguchi

bioRxivpreprint @biorxivpreprint.bsky.social · Dec 1

Sequence Composition Dictates Condensate Miscibility https://www.biorxiv.org/content/10.1101/2024.11.29.626135v1

Numerous biomolecular condensates coexist within cells, yet the mechanisms governing their mixing an

www.biorxiv.org

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Kyogo Kawaguchi @kyogok.bsky.social · Feb 14

I feel like this post is becoming even more relevant for our early-career researcher friends in the US—unless it’s already too late. It doesn’t have to be our lab or RIKEN; if you’re interested in coming to Japan, I’m always happy to chat!

Kyogo Kawaguchi @kyogok.bsky.social · Feb 4

We can host Special Postdoctoral Researchers (SPDR) for FY 2026. This is one of the best postdoc positions you can find in Japan, comparable to departmental or institutional fellowships in the US or Europe. Feel free to reach out if you’re interested!
www.riken.jp/en/careers/p...

Call for applications for the position of Special Postdoctoral Researcher (SPDR) for FY 2026

www.riken.jp

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Reposted by Kyogo Kawaguchi

Lisa Heinke @lisaheinke.bsky.social · Dec 10

Another of my favourite 2024 #NatRevMCB covers highlights our Review on #somitogenesis by Yuchuan Miao and Olivier Pourquie.

We were inspired by the rows of forming somites that resemble rows of seat on a train or plane and their patterning by Hox genes!

🔗 go.nature.com/3Vx3psy

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Kyogo Kawaguchi @kyogok.bsky.social · Feb 6

Happy to see this published! This work was led by Takahiro (a talented undergrad@UTokyo) and Kyosuke (a transdisciplinary theoretician@RIKEN). Dynamical phase transitions can occur even for an equilibrium Brownian motion if the dimension is larger than 4. journals.aps.org/prresearch/a...

Universality in the dynamical phase transitions of Brownian motion

We study the dynamical phase transitions (DPTs) appearing for a single Brownian particle without drift. We first explore how first-order DPTs in large deviations can be found even for a single Brownia...

journals.aps.org

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Kyogo Kawaguchi @kyogok.bsky.social · Feb 4

We can host Special Postdoctoral Researchers (SPDR) for FY 2026. This is one of the best postdoc positions you can find in Japan, comparable to departmental or institutional fellowships in the US or Europe. Feel free to reach out if you’re interested!
www.riken.jp/en/careers/p...

Call for applications for the position of Special Postdoctoral Researcher (SPDR) for FY 2026

www.riken.jp

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Kyogo Kawaguchi @kyogok.bsky.social · Feb 4

Starting in April 2025, our RIKEN Hakubi Lab will transition to a Chief Scientist Lab, and we plan to move to Wako in 2026. My affiliation with the IPI, Department of Physics at The University of Tokyo, will continue as before.

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Reposted by Kyogo Kawaguchi

Miki Ebisuya @ebisuyamiki.bsky.social · Jan 24

Latest from the lab!
I've been seeking the ultimate modulator that regulates the tempo of multiple developmental processes simultaneously, and metabolism has been an attractive candidate for such a global tempo modulator.
However, I was wrong. 1/
www.nature.com/articles/s41...

Metabolic activities are selective modulators for individual segmentation clock processes - Nature Communications

Metabolism has been considered an attractive candidate as a global modulator of the tempo of multiple developmental processes, including somite segmentation timing. Here they demonstrate that metaboli...

www.nature.com

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Reposted by Kyogo Kawaguchi

Kazunari Miyamichi @k-miyamichi.bsky.social · Dec 10

The sympathetic nervous system may control selective organs, but how this specificity is achieved is unknown. Our new study
@NatureComms www.nature.com/articles/s41...　uncovers a parallel labeled-line organization within the lower thoracic spinal cord. 1/

Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice - Nature Communications

How individual organs are specifically regulated by the sympathetic neurons at the cellular level remains not fully understood. Here, authors identify two molecularly distinct sympathetic pathways tha...

www.nature.com

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Reposted by Kyogo Kawaguchi

Jorge Lázaro @jorgelazaro.bsky.social · Nov 21

Thorough study comparing the vertebral formula of more than 388 tetrapod species. The relationship between Hox expression and vertebral identity is not trivial, specially in birds. www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

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Reposted by Kyogo Kawaguchi

Kazuhiro Maeshima @kazu-maeshima.bsky.social · Nov 30

We are seeking a motivated postdoc to join our lab! Our research focuses on live-cell imaging/analysis to reveal how chromatin behaves in living cells and how its behavior contributes to cellular functions.
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
Interested? Please DM me!

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Kyogo Kawaguchi @kyogok.bsky.social · Nov 29

@pnas.org is here nice.

Kyogo Kawaguchi @kyogok.bsky.social · Nov 27

And our new preprint! "Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture", biorxiv (2024). Led by Yohsuke T Fukai, in collaboration with Kurumizaka lab (U Tokyo) and Umehara lab (RIKEN BDR).

www.biorxiv.org/content/10.1...

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Kyogo Kawaguchi @kyogok.bsky.social · Nov 27

Recent collaboration: "A Percolation Model of Emergence: Analyzing Transformers Trained on a Formal Language", arXiv:2408.12578 (2024). With Ekdeep Lubana, Robert Dick, and Hidenori Tanaka.

arxiv.org/abs/2408.12578

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Kyogo Kawaguchi @kyogok.bsky.social · Nov 26

Recent work from our group: "Activity-induced ferromagnetism in one-dimensional quantum many-body systems", Phys. Rev. Research 6, 023096 (2024). With Kazuaki Takasan and Kyosuke Adachi.

doi.org/10.1103/Phys...