Lightnews — Scholar-powered news

Reposted by Laura Dearden

Diabetologia @diabetologiajnl.bsky.social · 29d

Up front & free to read in our Sept issue #editorspicks: Measurement of brain glucose metabolism in obesity and diabetes link.springer.com/article/10.1...

Measurement of brain glucose metabolism in obesity and diabetes - Diabetologia

The brain consumes a large amount of glucose to fuel its high metabolic demands. Understanding brain glucose metabolism is critical for understanding the brain’s normal physiology and the pathological...

link.springer.com

1 3

Laura Dearden @lauradearden.bsky.social · 29d

Having a fantastic time at DOHAD 2025 in the beautiful Buenos Aires. The best place for catching up with friends and collaborators!

4

Laura Dearden @lauradearden.bsky.social · Sep 3

congrats Jo, not least on the excellent shoelaces

Laura Dearden @lauradearden.bsky.social · Jul 29

I can’t be at #ssib2025 this year but the amazing Rosanne and L are there to present their data on the impact of maternal obesity/GDM on offspring hypothalamic development, and what metformin use in pregnancy does to the fetal brain.

2 7

Reposted by Laura Dearden

British Society for Neuroendocrinology @bsneuroendo.bsky.social · Jul 21

🏆 CONGRATULATIONS to Jo Lewis, 2025 winner of the Michael Harbuz Prize!

Jo will speak at #BSNBradford2025 on Glucose-dependent insulinotropic polypeptide regulates food intake and body weight via the area postrema in mice.

Register: bsnbradford2025.oa-e...

2 3

Reposted by Laura Dearden

Academy of Medical Sciences @acmedsci.bsky.social · Jul 2

The report calls for urgent action to:

🤰 Prioritise support during pregnancy
🍴 Ensure robust regulation of the food industry
🤝 Coordinate across govt departments i.e. food, education, urban planning and transport

Professor Susan Ozanne FMedSci next to a quote that reads: "The first 1,000 days, including time in the womb, represent an important window of opportunity to set children on a healthy trajectory for life. This isn’t about individual willpower or blaming and shaming – it's about creating an environment for parents, carers and their children that supports healthy development from the very beginning."

1 3 2

Reposted by Laura Dearden

Academy of Medical Sciences @acmedsci.bsky.social · Jul 2

🚨 Childhood obesity is rising at alarming rates around the world

Our latest report, with Italy’s Accademia Nazionale dei Lincei, calls for early intervention to ensure healthier futures for all children 🌱

Read the report: bit.ly/46qy7tN

And see our key takeaways 🧵

Child’s weight for life shaped by first 1,000 days, report health experts

bit.ly

1 5 3

Reposted by Laura Dearden

British Society for Neuroendocrinology @bsneuroendo.bsky.social · Jun 17

We've got something NEW for BSN ECRs!

🔬📹An Early Career Methodology video tutorial series

Our first tutorial is an Introduction to single-cell transcriptomics by Dr Sreekala Nampoothiri.

Watch: my.neuroendo.org.uk/...

Not a BSN member? Join today and get access: www.neuroendo.org.uk...

1 1

Reposted by Laura Dearden

Stina Börchers, PhD @stinaborchers.bsky.social · Jun 18

🧠🍽️ A "hunger switch" in the nose? Smelling food activates a pathway from the olfactory bulb to medial septum glutamatergic neurons in mice, triggering anticipatory satiety: making them feel full before eating.
This circuit works in lean mice but is disrupted in obesity.

#neuroskyence 🧪

A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism

The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.

www.nature.com

2 14 43

Reposted by Laura Dearden

Bradley Jamieson @bradleyjamieson.bsky.social · Jun 16

🎉 Thrilled to share my postdoc work, with our preprint out now on BiorXiv here: www.biorxiv.org/content/10.1...

We investigated how the juvenile brain develops the ability to carry out care behaviours towards neonates by an exciting and surprising switch in neural activity and behaviour

www.biorxiv.org

3 15

Reposted by Laura Dearden

Liisa Galea @liisagalea.bsky.social · Jun 16

Our latest review on perimenopause menopause and hormone therapy. What key issues have we missed and how can we do better from education to research to clinical care. With Laura Gravelsins! www.cambridge.org/core/journal...

One size does not fit all: how type of menopause and hormone therapy matters for brain health | The British Journal of Psychiatry | Cambridge Core

One size does not fit all: how type of menopause and hormone therapy matters for brain health

www.cambridge.org

5 11

Reposted by Laura Dearden

Ionel Sandovici @isandovici.bsky.social · Jun 4

Very cool paper connecting nutrition, epigenetics and developmental biology. rdcu.be/eptl7

Maternal iron deficiency causes male-to-female sex reversal in mouse embryos

Nature - Iron-deficient conditions in pregnant mice can cause XY mouse embryos to develop female rather than male genitalia, revealing that iron metabolism has a role in determining male sex in mice.

rdcu.be

1 4 9

Reposted by Laura Dearden

Meenakshi Asokan @meenakshiasokan.bsky.social · May 30

Stoked to share our new review on why neuroendocrinology needs a systems lens and why hormones should matter to systems neuroscience. It’s time for serious cross-talk!

Annegret Falkner @neurrriot.bsky.social · May 30

Is it finally time for systems neuroscience to take hormones seriously? OMG YES! @meenakshiasokan.bsky.social and I share some of our thoughts about recent work in this review www.sciencedirect.com/science/arti...

Hormonal regulation of behavioral and emotional persistence: Novel insights from a systems-level approach to neuroendocrinology

Gonadal sex steroid hormones regulate internal states, social drive, perception of external cues, and learning and memory. Fluctuating hormones influe…

www.sciencedirect.com

1 5 19

Reposted by Laura Dearden

RyanLab_TCD @ryanlab.bsky.social · Apr 30

It was fantastic to have @labliston.bsky.social give a talk at the @mrc-mbu.bsky.social on building a positive research culture. Valuable for all investigators/group leaders regardless of career stage, check out the resources below:
listonlab.uk/careers/

Translational Immunology - Careers

Becoming a Scientist

listonlab.uk

4 3

Reposted by Laura Dearden

Alessandro Bartolomucci Lab @bartolomuccilab.bsky.social · Apr 25

Food insecurity drives obesity and adiposity, but how is unclear.
A recent study by @clemmensenc.bsky.social developed a mouse model for this phenomenon lnkd.in/d8pEp2qv
Happy to share a commentary written with @johnspeakman4.bsky.social with our take on that study
doi.org/10.1002/oby....

Scarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in mice

Click on the article title to read more.

doi.org

1 5 7

Laura Dearden @lauradearden.bsky.social · Apr 30

I'm sure he would have had something to say, but maybe he already predicted this future in the books... narcissism of Vetinari and ignorance of Lord Rust...

Laura Dearden @lauradearden.bsky.social · Apr 30

1 1 3

Laura Dearden @lauradearden.bsky.social · Apr 26

That I would like to see!

1

Laura Dearden @lauradearden.bsky.social · Apr 25

Two pics from cycling around Cambridge this week. I really want to know what animal is being transported around in that basket!

1 1

Reposted by Laura Dearden

Nature @nature.com · Apr 24

Neurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress

https://go.nature.com/4lP2EHa

Memories of a cold place trigger bodily responses to warm up

Neurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress.

go.nature.com

17 52

Reposted by Laura Dearden

Madhu Pai, MD, PhD @madhupai.bsky.social · Apr 23

NIH cancels its first and largest study centered on women

www.science.org/content/arti...

NIH cancels its first and largest study centered on women

The Women’s Health Initiative has produced numerous influential findings

www.science.org

8 110 130

Reposted by Laura Dearden

Jeremy Berg @jeremymberg.bsky.social · Apr 21

The report with the underlying data for the Washington Post story about firings of disproportionate numbers of women and underrepresented minorities from NIH Boards of Scientific Counselors.

docs.google.com/document/d/1...

Letter_to_CongressApril16_2025_updated

April 16, 2025 (updated 4/21/2025) Senate Committee on Health, Education, Labor and Pensions House Committee on Energy and Commerce - Subcommittee on Health Washington, DC 20510 Report: Scientists...

docs.google.com

1 44 59

Laura Dearden @lauradearden.bsky.social · Apr 17

What a terrible loss to the field of obesity research and global health in general.

Kevin Hall @kevinh-phd.bsky.social · Apr 16

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.

2 7

Reposted by Laura Dearden

Orange Dick Tater Hater @realbiscuitspaw.bsky.social · Apr 11

300 3K 19K