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Reposted by Matt Whelan / Mathúin Ó Faoláin

FocalPlane @focalplane.bsky.social · 20d

📢 Join us next week for our mini-symposium with the membrane trafficking webinar series
Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.

FocalPlane features... membrane trafficking - FocalPlane

FocalPlane features... membrane trafficking - News

focalplane.biologists.com

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Sep 8

Great to see this in the wild!

Kate Morling @katemorling.bsky.social · Sep 2

Excited to share the preprint for our work on cyclosporine-based lentiviral transduction enhancer, BG147, which degrades innate immune barrier IFITM3, increasing gene delivery in gene therapy.

Huge thanks to everyone involved! @towerslab.bsky.social

www.biorxiv.org/content/10.1...

A modified cyclosporine enhances lentivector transduction ex vivo and in vivo by degrading IFITM3

Intrinsic innate immune barriers have evolved to suppress viral infection and can reduce effective gene delivery in gene therapy. We have developed BG147, a novel cyclosporine A analogue, optimised vi...

www.biorxiv.org

Reposted by Matt Whelan / Mathúin Ó Faoláin

Journal of Cell Science @jcellsci.bsky.social · Jul 16

Call for papers: Cell Biology of the Nucleus

We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social.
journals.biologists.com/jcs/pages/nu...

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jul 23

I'll be there!

Gautam Dey @gautamdey.bsky.social · Jul 23

1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler

Tons of open slots, invited and selected speakers all get 20 mins ❤️

#EESNucleus

Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jul 23

Really excited to be back in my home away from home, Berlin, for my first conference in Germany:

"Life at the Edge: The nuclear envelope in nucleocytoplasmic transport and genome organisation"

Really looking forward to it!

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Rita Strack @ritastrack.bsky.social · Jul 10

Come work at Nature Methods! A dream job. I know from experience 😄

Nature Methods @natmethods.nature.com · Jul 9

Nature Methods is hiring!
We are seeking a new editor with expertise in microscopy, imaging technology, and/or cell biology. The position is available in NYC/Jersey City or Shanghai/Beijing on a hybrid working model.
Apply by August 3!

springernature.wd3.myworkdayjobs.com/SpringerNatu...

a yellow sign that says we 're hiring

ALT: a yellow sign that says we 're hiring

media.tenor.com

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jul 10

Hyped to be moving to the Blizard Institute @qmul.bsky.social in the Autumn.

As part of an exciting new development in infection research within the Blizard, I’ll be a Group Leader, Academic Lead of the Blizard Advanced Light Microscopy (BALM) Facility and soon take up a Senior Lectureship.

Towers Lab @towerslab.bsky.social · Jul 10

We are delighted to be joining the Blizard Institute in Autumn. The Blizard Institute is an amazing place for discovery science and we're looking forward to more transformative research and collaborations.

www.qmul.ac.uk/blizard/abou...

Blizard Institute welcomes world-leading team of virologists

www.qmul.ac.uk

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jul 3

Hugely excited to work with this!

Ricardo Henriques @henriqueslab.bsky.social · Jul 3

It's here! ✨
The #ExSRRF protocol paper is out 😍. Full details for merging Expansion Microscopy with our eSRRF analysis. From cells to tissue. A partnership with @puellesv.bsky.social's lab. Lead by Dominik Kylies and @hannah-superres.bsky.social + colleagues. #ExM #eSRRF
➡️ Open link: rdcu.be/euvEw

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jun 11

This was a lot of fun!

Great to be back in my Alma Mater.

Siobhán McClean @siobhanmcclean.bsky.social · Jun 10

🧪Great talk by @mattvxwhelan.bsky.social in the @ucddublin.bsky.social Conway CLASS lecture.
Amazing images of HIV / Nuclear interactions

Title Slide reads “Visualising how HIV-1 signalling remodels nuclear pores to license infection” with an image of a CD4+ T cell Nuclear pore behind.

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · Jun 6

Great to see this out! And very fitting the last publication from my PhD is in a @microbiologysociety.org journal. Who played a significant role in supporting my EARLY early career!

Tadhg O Croinin @tadhgocroinin.bsky.social · Jun 5

New paper from @mattvxwhelan.bsky.social from his PhD looking at Campylobacter invasion of intestinal spheroids and
published in Microbiology. Remember supporting our society's journals ensures they can continue to support us!!
@microbiologysociety.org www.microbiologyresearch.org/content/jour...

An invasive phenotype induced by relaxation of DNA supercoiling in Campylobacter jejuni triggers disruption of tight junctions of intestinal spheroids

The relaxation of DNA supercoiling in Campylobacter jejuni leads to increased protein secretion and a more invasive phenotype, but little is known about the specific mechanisms involved. The aim of th...

www.microbiologyresearch.org

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Rita Strack @ritastrack.bsky.social · May 29

I cannot believe I didn't post about dark sectioning! I can only blame my crazy travel schedule. Check out this amazing tool for background removal in fluorescence microscopy. An important new concept, not 'just another' denoising algorithm.

xipeng1.bsky.social @xipeng1.bsky.social · May 16

Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems:
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · May 30

Would love that join!

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · May 23

Really great talk by @melghazaly.bsky.social from @towerslab.bsky.social in #CSH #Retroviruses !

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Jolly Lab @jollylab.bsky.social · May 21

Yesterday, @mattvxwhelan.bsky.social gave a fantastic talk! Thanks for all the engaging questions and all the great science chat afterwards! #cshretro

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · May 20

It was a huge honour to speak today in the beautiful locale of Cold Spring Harbor, Long Island, NY. At an epic post entry events session on the 50th anniversary of #CSH #Retroviruses

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · May 20

Can't wait for this!

Journal of Cell Science @jcellsci.bsky.social · May 19

After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti.
To register your interest: www.biologists.com/meetings/jcs...

Journal of Cell Science Meeting 2026
Imaging Cell Dynamics
Date: 11 – 14 May 2026
Venue: Montanyà Hotel, Catalonia, Spain
Register your interest

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Reposted by Matt Whelan / Mathúin Ó Faoláin

FocalPlane @focalplane.bsky.social · May 16

Our latest preprint list is now up on FocalPlane. Our list this week is focusses on research using 🔬microscopy tools to answer questions in biology.

As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/05/16/m...

Microscopy preprints - applications in biology - FocalPlane

Microscopy preprints - applications in biology - News

focalplane.biologists.com

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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · May 12

Join us at Virtual Virology for an afternoon of excellent science!

RM @rsbmilne.bsky.social · May 8

Virtual Virology is back - our first ever phage session. Do join us...

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Janelia Research Campus @hhmijanelia.bsky.social · May 9

🖱️ Picking out individual cells in distorted microscopy images is now as easy as clicking a button, thanks to Cellpose3: www.janelia.org/news/newest-...

Newest version of Cellpose can spot cell boundaries even in cloudy conditions

Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy

www.janelia.org

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Nature Methods @natmethods.nature.com · Mar 17

A computational framework links transcriptomic analyses with mechanical signatures to study the interplay between cell mechanical forces and gene expression.

www.nature.com/articles/s41...

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Ellenberg Lab @ellenberglab.bsky.social · Mar 19

We are #hiring!

We have two open postdoc/research scientist positions to join our #ERC funded project MITOFOLD to resolve the organization of mitotic chromosomes!

1) experimental biologist shorturl.at/LjGEM
2) data scientist shorturl.at/nDdhQ
Please share! 🙌

We look forward to your application! 🤩

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Austin E. Y. T. Lefebvre @austin-lefebvre.bsky.social · Feb 27

Do you LOVE organelles??
Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social!

Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy

🧵1/N

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Sketchy News @sketchynews.net · Feb 27

[Phys.Org]A completely new type of microscopy based on quantum sensors - Phys.org Researchers at the Technical University of Munich (TUM) have invented an entirely new field of microscopy called nuclear spin microscopy. The team can visualize magnetic signals of nuclear magnetic resonance with a...

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Reposted by Matt Whelan / Mathúin Ó Faoláin

Pablo Carravilla @pablo-carravilla.bsky.social · Feb 19

We wrote a protocol to quantify plasma membrane fluidity using a confocal microscope 🔬
Hopefully those interested in measuring membrane biophysical properties in live cells find it useful.
We also provide an ImageJ/Fiji tool to make the analysis as easy as possible.
www.nature.com/articles/s41...

Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols

Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...

www.nature.com

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Reposted by Matt Whelan / Mathúin Ó Faoláin

HHMI @hhmi.org · Feb 17

Bring your samples into focus! A new version of the #Cellpose cell boundary mapping tool, developed at @hhmijanelia.bsky.social by @computingnature.bsky.social and @marius10p.bsky.social, now works on less-than-perfect microscopy images that are noisy, blurry, or undersampled.

Newest version of Cellpose can spot cell boundaries even in cloudy conditions

Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy

buff.ly

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