This Medical News article is in remembrance of Atul Butte, MD, PhD, a pioneer in using data science to improve health.

Treg cells safeguard the intestinal barrier to prevent inflammaging and senescence in a mouse model of premature aging.

The aim of this systematic literature review was to provide a comprehensive overview of T-Cell Receptor (TCR) mediated immunity research in osteoarthritis (OA).

Atul Butte, who championed the use of big data in science and health care and inspired a generation of trainees at UC San Francisco and beyond to pursue the fields he pioneered — translational and cli...

In this Review article, the potential of cytometry- and single-cell RNA sequencing-based immune profiling for aiding the diagnosis and personalized treatment of rheumatic diseases is discussed.

Acute Foxp3 protein depletion selectively affects Treg cells responding to type 1 inflammation.

Osteoarthritis (OA) is now understood as a heterogeneous disease in many respects, including its clinical presentation, underlying pathophysiological mechanisms, and response to treatments. Distinct p...

Researcher and campus leader Atul Butte, MD, PhD, has been recognized for his outstanding career in the computational and health sciences with induction into the American Academy of Arts and Sciences,...

To investigate the association between intestinal permeability alteration and erosive hand osteoarthritis (EHOA).

Nature Reviews Rheumatology, Published online: 07 February 2025; doi:10.1038/s41584-025-01218-9Garrido-Mesa and Brown review findings from TCR profiling studies in rheumatic diseases and discuss how improved study design might help elicit information…