Mo Khalil
@mokhalil.bsky.social
1.2K followers
880 following
33 posts
Prof @ Boston University and Wyss Institute.
Synthetic & systems biology; directed evolution; protein & cell engineering; eVOLVER.
Trying to understand the living world by engineering a synthetic one.
Lab website: bu.edu/khalillab
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Mo Khalil
@mokhalil.bsky.social
· Aug 2
Reposted by Mo Khalil
Hiten Madhani
@hitenmadhani.bsky.social
· Jul 24
Phenotypic landscape of an invasive fungal pathogen reveals its unique biology
The construction and high-precision fitness profiling of a C. neoformans knockout
library reveals a high-resolution functional map of its genome and allowed for the
identification of fungal analogs of...
www.cell.com
Reposted by Mo Khalil
Mo Khalil
@mokhalil.bsky.social
· Jun 28
Reposted by Mo Khalil
Oded Rechavi
@odedrechavi.bsky.social
· Jun 27
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome
Defining the minimal genetic requirements for cellular life remains a fundamental question in biology. Genomic exploration continually reveals novel microbial lineages, often exhibiting extreme genome...
www.biorxiv.org
Reposted by Mo Khalil
Chang Liu
@chang-c-liu.bsky.social
· May 24
Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation - Nature Communications
Genetic code expansion (GCE) enables the incorporation of new amino acids into proteins. Here, authors demonstrate the rapid OrthoRep-driven evolution of aminoacyl-tRNA synthetases for GCE, increasing...
www.nature.com
Reposted by Mo Khalil
Reposted by Mo Khalil
John Ngo
@johntngo.bsky.social
· Apr 30
Meet John Ngo, Winner of the 2025 ACS Synthetic Biology Young Innovator Award | ACS Publications Chemistry Blog
Read an exclusive interview with Prof. Ngo covering his research, his history with the journal, and advice to early career researchers.
axial.acs.org