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Neha Ghosh

@nehaghosh.bsky.social

810 followers 600 following 150 posts

NIH K99 Postdoctoral Fellow-Treisman Lab NYU School of Medicine Tissue patterning| Organ morphogenesis #WomeninSTEM

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Neha Ghosh @nehaghosh.bsky.social · Aug 28

🚨pre-print alert🚨

Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Aug 27

Corneal lens curvature depends on localized chitin secretion https://www.biorxiv.org/content/10.1101/2025.08.22.671854v1

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Oded Rechavi @odedrechavi.bsky.social · 2d

Fwd: Fwd: “I hope this email finds you well”

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Nature @nature.com · 1d

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale

go.nature.com/3WnEUhE

Groundbreaking quantum-tunnelling experiments win physics Nobel

John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.

go.nature.com

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Reposted by Neha Ghosh

Development @dev-journal.bsky.social · 1d

Issue 18 is complete!

On the cover: Clones on Drosophila retina with activated Mbt kinase (pink), expanding Sdk protein (yellow) from tri- to bi-cellular adheren junctions & distorting the ommatidial lattice (cyan).

See Research Article by Gandhi et al.

journals.biologists.com/dev/article/...

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Itai Yanai @itaiyanai.bsky.social · 2d

Congratulations to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for this year's Nobel Prize in Physiology or Medicine. It also demonstrates the fairness of the prize, as Mary Brunkow is a Senior Program Manager (not a professor) at the @isbscience.org
hood.isbscience.org/people/mary-...

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Parvathy (She/Her) @parvathyv.bsky.social · 5d

I absolutely loved reading this one recently!

The authors show how AMPK (which is traditionally viewed as an stress-activated kinase) is also developmentally regulated by circulating adenosine levels in Drosophila.

www.nature.com/articles/s41...

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology

Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

www.nature.com

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Neha Ghosh @nehaghosh.bsky.social · 3d

Congratulations! 🎉 Adding this to my reading list.

Reposted by Neha Ghosh

Akankshi Munjal @akankshi.bsky.social · 12d

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

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MwahahahahahadScientist @mads100tist.bsky.social · 8d

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

Pathway to Independence: a forecast for the future of developmental biology

ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...

journals.biologists.com

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Thibaut Brunet @thibautbrunet.bsky.social · 3d

Latest from ours: www.cell.com/cell-reports...

This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

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Neha Ghosh @nehaghosh.bsky.social · 4d

Great choice! Nothing like a Bollywood Saturday 🙌

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Priti Agarwal @pritiagarwal.bsky.social · 6d

🚨 New preprint!
We profile the transcriptome of the C. elegans distal tip cell: a persistent leader cell that invades basement membrane to shape the gonad.

Our dataset defines the molecular signature of invasive leader cells & uncovers new regulators of collective cell invasion.

Stage-specific transcriptomics of a leader cell reveals cell machineries driving collective invasion

Collective cell invasion underlies organ development, epithelial repair, and cancer metastasis. Leader cells remodel extracellular matrix, sense guidance cues, reorganize their cytoskeleton, and coord...

www.biorxiv.org

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James Briscoe @jamesbriscoe.bsky.social · 5d

Mechanical constraints disrupt gastruloid polarisation without changing gene expression - uncouples morphogenesis & patterning

Gregor & co use tunable hydrogels to show cell motility, not gene expression, drives axis formation in gastruloids

journals.biologists.com/dev/article/...

Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids

Highlighted Article: A bioinert confinement system enables dissection of how stiffness and timing shape gastruloid development, revealing uncoupling between polarization and transcriptional programs.

journals.biologists.com

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Neha Ghosh @nehaghosh.bsky.social · 5d

To you too ☺️

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Mongabay @mongabay.com · 6d

Jane Goodall, who revealed the intimate lives of chimpanzees and gave the modern world a language of hope, has died at the age of 91.

“Every individual matters. Every individual has a role to play. Every individual makes a difference,” she told audiences. Those words remain her truest epitaph.

Jane Goodall (1934–2025): primatologist, conservationist, and messenger of hope

Jane Goodall, who revealed the intimate lives of chimpanzees and gave the modern world a language of hope, has died at the age of 91. Over the course of six decades, she moved from an unlikely young…

news.mongabay.com

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Eric Topol @erictopol.bsky.social · 6d

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 7d

Cool Postdoc opportunity alert! UNC SPIRE (Seeding Postdoctoral Innovators in Research & Education)-it provides scholars with both high quality research training & the opportunity to develop research based teaching skills that will inspire students across the sciences 1/n
spire.unc.edu/program-info/

About Seeding Postdoctoral Innovators in Research & Education (SPIRE)

SPIRE’s Mission:

1) To provide scholars with both high quality research training and the opportunity to develop research based teaching skills that will inspire students across the sciences

2) To promote effective teaching and research partnerships between research intensive institutions and partner institutions with a large population of underrepresented students

The four major components of the SPIRE Postdoctoral Fellowship Program include:

Research
Teaching
Professional Development
Additional Opportunities

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Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Prof Sheena Cruickshank @sheencr.bsky.social · 14d

This is very exciting! A small clinical trial using gene therapy for Huntington's disease has been successful. microRNAs were used to edit the Huntington mRNA, stopping it making mutant protein that can damage neurons. Huge hopes now for treating such a devastating condition

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

www.bbc.co.uk

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Maik Bischoff @maikbischoff.bsky.social · 14d

1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Neha Ghosh @nehaghosh.bsky.social · 13d

Very interesting idea of “directed mesenchymal self-patterning”. I will be diving into the perspective to find out more. Congratulations 🎉

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Meera Sundaram @meera-sundaram.bsky.social · 16d

The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...

aECM Club Seminars

A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…

sundaramlab.com

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Neha Ghosh @nehaghosh.bsky.social · 18d

Thank you 😊

Reposted by Neha Ghosh

Mathieu Preußner @mathpreu.bsky.social · 21d

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Excited to share my first PhD paper, published in @dev-journal.bsky.social
What if fish gills —often overlook —hold secrets about development, patterning, and function?
We uncovered how early patterning shapes adult gill architecture.
journals.biologists.com/dev/article/...

#DevBio #Zebrafish

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Daniel Alber @danielalber.bsky.social · 20d

A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis!

Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)

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Neha Ghosh @nehaghosh.bsky.social · 19d

Many congratulations, Daniel!