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Reposted by Omkar Joshi

Sylvain Gabriele @sgabriele.bsky.social · Aug 25

Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳

Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻

Enjoy the reading www.nature.com/articles/s41...

The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics

Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...

www.nature.com

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Rita Strack @ritastrack.bsky.social · Aug 1

I have some BIG NEWS to share today!

Today I begin my next adventure as

Chief Editor of Nature Biomedical Engineering!!

(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com

a bunch of balloons are flying in the sky .

ALT: a bunch of balloons are flying in the sky .

media.tenor.com

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Omkar Joshi @omkarjoshi.bsky.social · Jul 31

I'm so sorry. Could you confirm if the heating is switched on 😉

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Omkar Joshi @omkarjoshi.bsky.social · Jul 17

Wow

Christian Frezza @frezzalab.bsky.social · Jul 16

www.nature.com/articles/s41...

anything that mitochondria are not involved?

Mitochondrial origins of the pressure to sleep - Nature

Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

www.nature.com

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Reposted by Omkar Joshi

Guillaume Jacquemet @guijacquemet.bsky.social · Jun 23

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

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Reposted by Omkar Joshi

Michalis Gounis @gounismichalis.bsky.social · Jun 9

1/ Beyond thrilled to see my #PhD work now published in @jcb.org
A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados

Journal of Cell Biology @jcb.org · Jun 9

@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...

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Journal of Cell Biology @jcb.org · Jun 9

@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...

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Johanna Ivaska @johannaivaska.bsky.social · May 26

Latest from @ivaskalab.bsky.social @jrwconway.bsky.social in NCB. We find that SHP-2 inhibition stops TNBC invasion and limits metastasis by blocking integrin dephosphorylation!

Read more at:

www.nature.com/articles/s41...

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology

Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

www.nature.com

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James Conway @jrwconway.bsky.social · May 26

New paper from @ivaskalab.bsky.social out now! 🍾 Watch how cancer cell adhesion dynamics are disrupted by inhibiting the phosphatase Shp2 - key to integrin β1 phosphorylation. Blocking Shp2 impairs adhesion and reduces invasion potential. 🎥👇 Read more at: www.nature.com/articles/s41...

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Ivaska Lab @ivaskalab.bsky.social · May 26

Our newest paper is out in NCB. @jrwconway.bsky.social‬ designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...

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Omkar Joshi @omkarjoshi.bsky.social · May 20

Amazing news! Warm congratulations to @johannaivaska.bsky.social for the award. Super proud!

www.utu.fi/en/news/news...

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Reposted by Omkar Joshi

Naba Lab UIC @nabalabuic.bsky.social · May 17

📣 Pre-print alert: Excited to have collaborated with Pam Kreeger and Kristyn Masters on this study showing that fibronectin composition and transglutaminase 2 crosslinking cooperatively regulate ovarian cancer cell adhesion in ECM-mimetic constructs.
www.biorxiv.org/content/10.1...

Collagen content of the human omentum and human omental HGSOC metastasis.

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Ivaska Lab @ivaskalab.bsky.social · May 10

New preprint alert!📣 @midibu.bsky.social and team take a deep dive into Tensin1 liquid-liquid phase separation (LLPS) and the mechanisms of how it regulates adhesion dynamics!
Check out the preprint here: www.biorxiv.org/content/10.1...
@johannaivaska.bsky.social

Adhesion-derived condensates control component availability to regulate adhesion dynamics

Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

www.biorxiv.org

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Michal Dibus @midibu.bsky.social · May 9

Happy to share our Tensin 1 phase separation project is now on bioRxiv.
www.biorxiv.org/content/10.1...

This wouldn't be possible without
@johannaivaska.bsky.social
@ivaskalab.bsky.social
#VattulainenLab
#MSCA by @ec.europa.eu
@turkubioscience.bsky.social
@inflames-flagship.bsky.social

Adhesion-derived condensates control component availability to regulate adhesion dynamics

Integrin adhesion complexes mediate cell-extracellular matrix (ECM) interactions and undergo dynamic remodelling to regulate cell adhesion and migration. Here, we demonstrate that tensin 1 (TNS1), a m...

www.biorxiv.org

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Omkar Joshi @omkarjoshi.bsky.social · May 7

I'm at the Fibronectin GRC till the end of the week! Come say hi and I'll tell you a bit about mitochondrial near focal adhesions😉

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TanentzapfLab @tanentzapflab.bsky.social · Jan 22

A reminder to colleagues interested in Cell-Matrix adhesion & anything ECM related that registration is now open for the Fibronectin, Integrins & related molecules Gordon Research Conference. Incredible list speakers! incredible location! it will 🔥 🔥 🔥 Please join us! www.grc.org/fibronectin-...

2025 Fibronectin, Integrins and Related Molecules Conference GRC

The 2025 Gordon Research Conference on Fibronectin, Integrins and Related Molecules will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

www.grc.org

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Reposted by Omkar Joshi

Michal Dibus @midibu.bsky.social · Mar 26

Grateful for the opportunity to participate in this Viewpoint with @follainga.bsky.social , @omkarjoshi.bsky.social and @guijacquemet.bsky.social :
Time, the final frontier
doi.org/10.1002/1878...

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Guillaume Jacquemet @guijacquemet.bsky.social · Mar 24

We wrote a small Viewpoint for Molecular Oncology with
@follainga.bsky.social

@omkarjoshi.bsky.social

Michal Dibus

via EACR
@helloeacr.bsky.social

Time, the final frontier
febs.onlinelibrary.wiley.com/doi/full/10....

Hope you find it interesting

febs.onlinelibrary.wiley.com

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Journal of Cell Biology @jcb.org · Mar 21

In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...

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A/Prof Sam Stehbens PhD (She/Her) @samstehbens.bsky.social · Mar 22

If you are planning your conferences for the year- keep an eye out for EACR’s Goodbye Flat Biology! Essen 23-25 Sept 2025
www.eacr.org/conference/goodbyeflatbiology2025

#CancerResearch #Oncology I’ll see you there. :)
@helloeacr.bsky.social

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Emilia Peuhu @epeuhu.bsky.social · Mar 20

We are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️
ats.talentadore.com/apply/vaitos...
📸 @oonapaavolainen.bsky.social

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Omkar Joshi @omkarjoshi.bsky.social · Mar 14

Thank you @focalplane.bsky.social for featuring my image!

FocalPlane @focalplane.bsky.social · Mar 14

It’s #FluorescenceFriday and we are pleased to share this beautiful image from
@omkarjoshi.bsky.social. Read more about the image and Omkar’s research in our accompanying post: focalplane.biologists.com/2025/03/14/f...

Featured image with Omkar Joshi - FocalPlane

Featured image with Omkar Joshi - News

focalplane.biologists.com

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Turku Bioscience @turkubioscience.bsky.social · Mar 7

🎉 Great success for Turku Bioscience Centre at the 3MT competition!

Congrats to Rahul Birdar (@lahesmaalab.bsky.social) for securing 2nd place and Omkar Joshi (@ivaskalab.bsky.social) for being selected to represent @utu.fi in the international 3MT competition by the SANORD network! 👏 #3MT #SANORD

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Oded Rechavi @odedrechavi.bsky.social · Mar 1

Friends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW!
woodstock.img.cas.cz

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Helen Matthews @helenkmatthews.bsky.social · Feb 24

🚨 PhD position available for Oct 25

🔬Using advanced microscopy to understand how keratin networks control tissue mechanics

An interdisciplinary #cellbiology #biophysics collaboration with Ruby Peters & @alicepyne.bsky.social

👇 Apply by March 14

www.findaphd.com/phds/project...

Micrograph of keratin networks (green) and DNA (blue) within cells
Image by Rachel Lawson

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