Paul Masset
@paulmasset.bsky.social
3.7K followers 1.1K following 31 posts
Assistant Professor, McGill University | Associate Academic Member, Mila - Quebec AI Institute | Neuroscience and AI, learning and inference, dopamine and cognition https://massetlab.org/
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Reposted by Paul Masset
annaweinberg.bsky.social
Delighted to share that we are currently hiring for a tenure-track position (open rank) in Clinical Psychology in the Department of Psychology at McGill University. Come join a great department! Link to apply: mcgill.wd3.myworkdayjobs.com/en-US/mcgill....
McGill University in early Autumn
Reposted by Paul Masset
gershbrain.bsky.social
This is one of the most outstanding examples of circuit understanding I've seen in a long time. The unification of theory and experiment is beautiful.

When Malcolm presented this in my lab, the audience was cheering at the end, and one person shouted (non-ironically) "You did it!"
malcolmgcampbell.bsky.social
🚨Our preprint is online!🚨

www.biorxiv.org/content/10.1...

How do #dopamine neurons perform the key calculations in reinforcement #learning?

Read on to find out more! 🧵
Reposted by Paul Masset
guillaumeviejo.bsky.social
Finally preprinted! TL;DR: thalamic head-direction neurons can shape their activity regardless of input. Big thanks to @apeyrache.bsky.social and master experimentalist @sskromne.bsky.social .
apeyrache.bsky.social
🚨New preprint alert!

The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.

Some explanation 🧵👇 1/13

www.biorxiv.org/content/10.1...
Coherent dynamics of thalamic head-direction neurons irrespective of input
While the thalamus is known to relay and modulate sensory signals to the cortex, whether it also participates in active computation and intrinsic signal generation remains unresolved. The anterodorsal...
www.biorxiv.org
Reposted by Paul Masset
apeyrache.bsky.social
Stoked to see this paper finally out!

It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks.

Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm.

www.science.org/doi/10.1126/...
Reposted by Paul Masset
evoneuro.bsky.social
For anyone on the neuroscience job market, our ads are up. We are looking for anyone working in systems neuroscience of animals to join us in southern Alberta 🇨🇦
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...
Assistant Professor (Neuroscience, Tenure Track) - Lethbridge (City), Alberta (CA) job with University of Lethbridge | 39049
Assistant Professor (tenure track) of the Department of Neuroscience at the University of Lethbridge, Alberta, Canada
neurojobs.sfn.org
Reposted by Paul Masset
Reposted by Paul Masset
gunnarblohm.bsky.social
Having fun facilitating this amazing group of young Profs at the #Neuro4Pros workshop with @kordinglab.bsky.social and @meganakpeters.bsky.social, @yaelniv.bsky.social, and Hannah Bayer.

Watch out world: this is the next generation of leaders!

compneurosci.com/Neuro4Pros/i...
Reposted by Paul Masset
evoneuro.bsky.social
For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more
#neuroskyence #academicsky
Reposted by Paul Masset
mattperich.bsky.social
🚨 I’m excited to say that my CIHR Project Grant was funded! My NHP lab is now full-speed-ahead, and I’m hiring experimentalists (postdoc, PhD student, and/or a tech/manager). We’ll do multi-region ephys during reaching/grasping in macaques, with behavioral and spinal perturbations.
Reposted by Paul Masset
payampiray.bsky.social
New paper with @nathanieldaw.bsky.social in Nature Communications: an RL model that builds a successor map compositionally. The new model plans as well as the best models, and it links components of the map used for planning to neural codes in the medial entorhinal cortex.
rdcu.be/eAofi
Reconciling flexibility and efficiency: medial entorhinal cortex represents a compositional cognitive map
Nature Communications - How the brain creates compositional cognitive maps that support both flexible and efficient planning remains poorly understood. Here, authors propose a...
rdcu.be
Reposted by Paul Masset
Reposted by Paul Masset
anna-beyeler.bsky.social
👨‍💻 Open PI position in our institute 👨‍💻 !! If you are an expert in Computational Neuroscience and want to start your lab in Bordeaux, contact us !
www.fens.org/careers/job-...
@neuromagendie.bsky.social
@neurobordeaux.bsky.social
Reposted by Paul Masset
marcelomattar.bsky.social
Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...
Discovering cognitive strategies with tiny recurrent neural networks - Nature
Modelling biological decision-making with tiny recurrent neural networks enables more accurate predictions of animal choices than classical cognitive models and offers insights into the underlying cog...
doi.org
Reposted by Paul Masset
justuskebschull.bsky.social
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.
Reposted by Paul Masset
dlevenstein.bsky.social
Thrilled to announce I'll be starting my own neuro-theory lab, as an Assistant Professor at @yaleneuro.bsky.social @wutsaiyale.bsky.social this Fall!

My group will study offline learning in the sleeping brain: how neural activity self-organizes during sleep and the computations it performs. 🧵
Reposted by Paul Masset
laklab.bsky.social
Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...
Reposted by Paul Masset
dvnxmvlhdf5.bsky.social
Preprint Alert 🚀

Multi-agent reinforcement learning (MARL) often assumes that agents know when other agents cooperate with them. But for humans, this isn’t always the case. For example, plains indigenous groups used to leave resources for others to use at effigies called Manitokan.
1/8
Manitokan are images set up where one can bring a gift or receive a gift. 1930s Rocky Boy Reservation, Montana, Montana State University photograph. Colourized with AI
paulmasset.bsky.social
To conclude our study establishes a new paradigm to understand the functional role of prediction error computation in dopaminergic neurons and opens new avenues to develop mechanistic explanations for deficits in intertemporal choice in disease and inspire the design of new RL algorithms.