banner
philippedomenech.bsky.social
Philippe Domenech
@philippedomenech.bsky.social
1.2K followers 1.8K following 42 posts
Computational neuroscientist and Full Prof in Psychiatry @ University of Paris, Head of Neuromodulation Institute at GHU Paris, Psychiatry Neurosciences
Posts Media Videos Starter Packs
Pinned
philippedomenech.bsky.social
Philippe Domenech @philippedomenech.bsky.social · Apr 4
🚨 !!! New preprint !!! 🚨
Excited to share my student @samibeaumont’s latest work, where we demonstrate that inference over putative strategies is sufficient to fully accounts for human adaptation across diverse statistical contexts, when reinforcement learning cannot. 🧠🟦 🧠🤖
#Neuroscience #Preprint
samibeaumont.bsky.social
Sami Beaumont @samibeaumont.bsky.social · Apr 4
Excited to share our preprint: "Recasting adaptation as strategy inference". This work explores how humans spontaneously adapt to changes by inferring strategies, rather than relying on incremental learning.@philippedomenech.bsky.social @khamascience.bsky.social @computationalbrain.bsky.social 🧠🟦 🧠🤖
Recasting adaptation as strategy inference
Flexible adaptation to uncertain and changing environments requires dynamic adjustments in behavioral strategies. While classical learning theories emphasize incremental strengthening of local stimulu...
tinyurl.com
2 13
Reposted by Philippe Domenech
hannahritchie.bsky.social
Hannah Ritchie @hannahritchie.bsky.social · Jun 9
Tuberculosis still kills around 1.3 million people every year.

It was once a massive killer in Europe and the US, but not anymore. How did these countries manage to tackle it?

Our first article on TB in a three-part series: ourworldindata.org/tuberculosis...
6 24 76
Reposted by Philippe Domenech
sufs-paris-rp.bsky.social
Stand Up for Science Paris et région parisienne @sufs-paris-rp.bsky.social · Jun 19
Les visas des chercheurs, des universitaires et des étudiants pour les Etats-Unis ne seront pas accordés à celles et ceux qui ont exprimé de l'hostilité au régime autoritaire de Trump. Ces refus de visa se feront par analyse des posts sur les réseaux sociaux.
www.nytimes.com/2025/06/18/u...
U.S. to Review Social Media Posts of Student and Scholar Visa Applicants
www.nytimes.com
12 110 96
philippedomenech.bsky.social
Philippe Domenech @philippedomenech.bsky.social · Jun 8
www.lemonde.fr/economie/art...
Derrière la grave pénurie française de médicaments psychotropes, une défaillance industrielle
Plus de la moitié des pharmacies disposent de moins d’un jour de stock de traitements-clés pour les personnes bipolaires ou en dépression. L’arrêt à l’automne 2024 d’une usine grecque qui fabrique, po...
www.lemonde.fr
1 2
philippedomenech.bsky.social
Philippe Domenech @philippedomenech.bsky.social · Jun 7
photo of a girl sitting in an airplane, working on her laptop and wearing headset. A sheet of paper hide her face and reads : "please do not talk to me. I have no self control + will talk to you the whole flight + I have to finish this paper. Thank you"
2 8
Reposted by Philippe Domenech
vincentcostaphd.bsky.social
Vinny Costa @vincentcostaphd.bsky.social · Jun 6
This is fantastic, causal work demonstrating the basal ganglia’s role in explore-exploit decision making www.nature.com/articles/s41...
Basal ganglia deep brain stimulation restores cognitive flexibility and exploration-exploitation balance disrupted by NMDA-R antagonism - Nature Communications
Deep brain stimulation of the basal ganglia restores cognitive flexibility and rebalances exploration disrupted by NMDA receptor antagonism in nonhuman primates, offering insights into the neural basi...
www.nature.com
7 17
Reposted by Philippe Domenech
jakphd.bsky.social
Jack Kosmicki @jakphd.bsky.social · Jun 6
Year ago, the prevailing attitude was that deep learning would significantly improve polygenic risk scores (or anything else, to be fair).

A rather important set of negative results indicating that isn't the case (though I imagine many will still try).
nature.com/articles/s41...
3 7 21
Reposted by Philippe Domenech
stepalminteri.bsky.social
Stefano Palminteri @stepalminteri.bsky.social · May 26
New in Nature MentalHealth! with Vrizzi, Najar, Lemogne, and @mael-lebreton.bsky.social

We tested whether behavioural and RL-based model parameters are test-retest reliable and predict mental health traits.

The result? Not really.

A cautionary tale for comp. psychiatry
doi.org/10.1038/s442...
Behavioral, computational and self-reported measures of reward and punishment sensitivity as predictors of mental health characteristics - Nature Mental Health
Reinforcement learning task-based behavioral and computational measures displayed low test–retest reliability at the individual level. Also in contrast to self-assessed personality measures, behaviora...
doi.org
2 28 54
Reposted by Philippe Domenech
imagingneurosci.bsky.social
Imaging Neuroscience @imagingneurosci.bsky.social · May 7
New paper in Imaging Neuroscience by Britta U. Westner, Tim M. Tierney, et al:

Cycling on the Freeway: The perilous state of open-source neuroscience software

doi.org/10.1162/imag...
22 35
Reposted by Philippe Domenech
hos-asa.bsky.social
American Statistical Association History of Statistics @hos-asa.bsky.social · May 11
#OTD 1920 Edward Kaplan b (d 26 Sep 2006) Best known for 1958 "sleeper hit" paper describing what is now known as the Kaplan–Meier product-limit statistic for survival & lifetime data. Now one of the most cited statistics papers of modern times, it took >12 yrs to catch on. 🧵/6
1 1 7
Reposted by Philippe Domenech
pardoguerra.bsky.social
This skeet will self destruct @pardoguerra.bsky.social · May 5
$500 million is… less than 1.25% of the NIH’s 2024 budget.

When I say there is no capacity to absorb the shock, I mean it.
vonderleyen.ec.europa.eu
Ursula von der Leyen @vonderleyen.ec.europa.eu · May 5
We will put forward a 500 million package for 2025-2027 to make Europe a magnet for researchers.

As well as ambitious proposals for R&I in the next EU budget.

We will also offer the best and brightest the right incentives to come to Europe ↓
18 340 970
Reposted by Philippe Domenech
xkcd.com
Randall Munroe @xkcd.com · Apr 25
PhD Timeline xkcd.com/3081
600 21K 60K
Reposted by Philippe Domenech
nytimes.com
The New York Times @nytimes.com · Apr 25
Breaking News: A federal prosecutor interrogated the The New England Journal of Medicine — which is considered the world’s most prestigious medical journal — in what its editor described as a “vaguely threatening” letter.
‘Vaguely Threatening’: Federal Prosecutor Queries Leading Medical Journal
The New England Journal of Medicine received a letter suggesting that it was biased and compromised by external pressure. Other journals have also received the letter.
www.nytimes.com
210 1.5K 3.3K
Reposted by Philippe Domenech
drsusanoliver.bsky.social
Dr Susan Oliver (PhD) @drsusanoliver.bsky.social · Apr 25
New study in JAMA. Modelling shows that at current state-level vaccination rates, measles may become endemic again in the USA. If rates continue to decline, ditto for rubella, poliomyelitis and diphtheria, leading to many preventable hospitalisations and deaths.
jamanetwork.com/journals/jam...
Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US
This study estimates the number of cases and complications in the US under scenarios of declining childhood vaccination for measles, rubella, poliomyelitis, and diphtheria.
jamanetwork.com
16 120 310
Reposted by Philippe Domenech
colehurwitz.bsky.social
Cole Hurwitz @colehurwitz.bsky.social · Apr 21
Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social !

We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠
1 19 70
Reposted by Philippe Domenech
caulfieldtim.bsky.social
Timothy Caulfield @caulfieldtim.bsky.social · Apr 20
Such a dangerous idea.

US attorney demands scientific journal explain how it ensures 'viewpoint diversity' www.nbcnews.com/science/scie...

Process of science – a human endeavour – full of biases. Key to recognize & counter.

But can’t let false balance & middle ground fallacies taint research.
U.S. attorney demands scientific journal explain how it ensures 'viewpoint diversity'
The unusual letter caught the attention of First Amendment groups and some scientists, who raised concerns it was designed to suppress academic and scientific freedom.
www.nbcnews.com
14 40 160
Reposted by Philippe Domenech
earlkmiller.bsky.social
Earl K. Miller @earlkmiller.bsky.social · Apr 20
Trump proposes massive NIH budget cut and reorganization
www.science.org/content/arti...
Trump proposes massive NIH budget cut and reorganization
Will Republican-led Congress support a 44% decrease for world’s largest medical research funder?
www.science.org
1 9 14
philippedomenech.bsky.social
Philippe Domenech @philippedomenech.bsky.social · Apr 20
english.elpais.com/internationa...
EU to double funding to attract US scientists fleeing Trump
The European Commission acknowledges its interest in the ‘opportunity’ generated by the cuts and obstacles promoted by the Republican administration
english.elpais.com
3 8
Reposted by Philippe Domenech
nature.com
Nature @nature.com · Apr 20
The world now has a plan for when the next global pandemic hits

https://go.nature.com/43X27wg
First global pandemic treaty agreed — without the US
The World Health Organization accord promotes sharing scientific data in exchange for more equitable distribution of drugs and vaccines.
go.nature.com
5 44 150
Reposted by Philippe Domenech
drlaurahaynes.bsky.social
Laura Haynes👩‍🔬⚾️🐾💙 @drlaurahaynes.bsky.social · Apr 19
My first Saturday morning coffee on my deck this season 😎☕️
420 2.6K 21K
philippedomenech.bsky.social
Philippe Domenech @philippedomenech.bsky.social · Apr 18
www.lemonde.fr/sciences/art...
Emmanuel Macron appelle les chercheurs internationaux à « choisir » la France et l’Europe, avec un « rendez-vous le 5 mai »
Avant ce rendez-vous, une plateforme baptisée « Choose France for Science » a été lancée jeudi par le gouvernement. Il la présente comme « une première étape pour préparer l’accueil des chercheurs int...
www.lemonde.fr
1
Reposted by Philippe Domenech
paulchopelin.bsky.social
Paul Chopelin @paulchopelin.bsky.social · Apr 17
Intéressante tribune sur l'illusion d'une université française attractive pour les chercheurs américains tentés par l'exil.
Ou de l'incapacité de regarder en face les conséquences de sa propre politique. Terrible absence de sens des responsabilités...
www.lemonde.fr/sciences/art...
Accueillir les chercheurs américains en France , « une ambition louable, mais irréaliste »
TRIBUNE. L’universitaire Théo Besson rappelle, dans une tribune au « Monde », que le manque criant d’investissement ainsi que le niveau des salaires dans la recherche française interdisent de fantasme...
www.lemonde.fr
6 67 160
Reposted by Philippe Domenech
ar0mcintosh.bsky.social
Randy McIntosh @ar0mcintosh.bsky.social · Apr 13
"The work we reviewed here supports an alternative view that the manifold and circuit approaches to cognition are inseparable." Can I get an amen? 😊

www.nature.com/articles/s41...
A unifying perspective on neural manifolds and circuits for cognition - Nature Reviews Neuroscience
Neural manifolds can shed light on how heterogeneous neuronal population activity drives neural computations, but linking these insights to the underlying neuronal connectivity is challenging. Engel a...
www.nature.com
1 11 56
Reposted by Philippe Domenech
psymassondavid.bsky.social
David Masson @psymassondavid.bsky.social · Apr 12
"Quand Nicolas Demorand "révèle" qu'il souffre de trouble bipolaire de type 2, il ne dit rien de son affaire" 😡

En tant que psychiatre, je suis vraiment très en colère à la lecture de cet article de Charlie Hebdo de cette semaine.

Un post n'est pas suffisant pour l'exprimer⬇️
Article de Charlie Hebdo
14 78 170
Reposted by Philippe Domenech
mvugt.bsky.social
Marieke van Vugt @mvugt.bsky.social · Apr 11
Tips for getting started with Bayesian statistics dx.plos.org/10.1371/jour...
Ten quick tips to get you started with Bayesian statistics
dx.plos.org
1 13 27
Reposted by Philippe Domenech
nilskolling.bsky.social
Nils Kolling @nilskolling.bsky.social · Apr 8
Registrations for the Symposium for the Biology of decision making (SBDM) in Lyon 2025 are finally open! sbdm2025.github.io Please spread the message!
10 23