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Reposted by Proteases and Innate immunity lab @ York

UK Cellular Microbiology @ukcellmicro.bsky.social · 2d

SAVE THE DATE!

The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast.

Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions.

Follow us to stay tuned! www.ukcellmicro.org

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Broz Lab @brozlab.bsky.social · 6d

The second day of the @dib-unil.bsky.social #PRR symposium kicks off with more excellent talks including our own Jakub Began.

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Avinash Shenoy @avishenoy.bsky.social · 10d

📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵
biorxiv.org/content/10.1...

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Reposted by Proteases and Innate immunity lab @ York

Adrian Liston @labliston.bsky.social · 19d

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

currentprotocols.onlinelibrary.wiley.com

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · 27d

Ready to start 2 days of everything innate immunity and inflammation #bsiinflammation2025
@britsocimm.bsky.social

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Pablo Pelegrin @ppelegrin.bsky.social · Sep 7

Looking for passionate candidate to apply to PhD fellowship to University of Murcia call:

www.um.es/documents/d/...

Interested students contact me!

www.um.es

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Ivan Zanoni @lozanzi.bsky.social · Sep 3

#MycobiotaPower! Exciting work @nature.com by Behnsen, Jaswal &co showing that #Salmonella uses type 3 secretion system to hijack #Candida_albicans to produce arginine in the gut, boosting Salmonella infectivity & reducing the immune response! www.nature.com/articles/s41...

Commensal yeast promotes Salmonella Typhimurium virulence - Nature

Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.

www.nature.com

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Reposted by Proteases and Innate immunity lab @ York

Dr Rebecca Coll @colllab.bsky.social · Sep 2

So excited that this study is now online! It's been a pleasure to work with BioAge Labs and our collaborators on this story. We characterise a new class of #NLRP3 inhibitors with translational potential for so many inflammatory diseases.

Journal of Experimental Medicine @jem.org · Sep 2

#NLRP3 is a target for antiinflammatory therapies & can be inhibited by the tool compound MCC950. Wilhelmsen, @colllab.bsky.social et al characterize new small-molecule inhibitors, BAL-0028 & BAL-0598, that have a distinct mechanism of action & binding site. rupress.org/jem/article/...
#Inflammasome

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · Sep 1

Still time to register for the BSI inflammation meeting 2025! Don’t miss out on this fantastic meeting !.

British Society for Immunology @britsocimm.bsky.social · Jul 15

🔥 Last call! Today’s the FINAL day to submit your abstract for “Innate immunity & inflammation: UK inflammation 2025.”

Don’t miss your chance to get involved! Submit now and join leading experts this September in Manchester.

Event & submission info: bit.ly/43q9x9r

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · Aug 3

10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling - Journal of Biological Chemistry www.jbc.org/article/S002...

10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling

Caspases are a family of cysteine proteases conserved across all multicellular life which play critical functions that range from cell death, inflammation and cellular differentiation. Caspases cleave...

www.jbc.org

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Reposted by Proteases and Innate immunity lab @ York

Department of Biology, University of York @biologyatyork.bsky.social · Jul 22

(1/3) We've been catching up with our GenerationResearch students so far this summer..!

"Hi, I am Naomi, a Biomedical Sciences student going into the final year of my Integrated Masters at York. I am currently doing my Generation Research studentship in Dave Boucher's Lab.

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Reposted by Proteases and Innate immunity lab @ York

British Society for Immunology @britsocimm.bsky.social · Jul 15

🔥 Last call! Today’s the FINAL day to submit your abstract for “Innate immunity & inflammation: UK inflammation 2025.”

Don’t miss your chance to get involved! Submit now and join leading experts this September in Manchester.

Event & submission info: bit.ly/43q9x9r

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Reposted by Proteases and Innate immunity lab @ York

Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · Jul 7

Still time to register to the next BSI Innate Immunity and Inflammation meeting. Join us for 2 days packed with great science and networking opportunities!

Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · May 28

Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!

British Society for Immunology @britsocimm.bsky.social · May 28

Dive into cutting-edge innate immunity & inflammation science at our event on September 11!

From immune cell roles to inflammasome signalling, discover advances shaping clinical care.

📆Abstract deadline: 15 July
🐦Early bird registration ends: 27 August

🔗 bit.ly/43q9x9r

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · Jul 7

Still time to register to the next BSI Innate Immunity and Inflammation meeting. Join us for 2 days packed with great science and networking opportunities!

Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · May 28

Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!

British Society for Immunology @britsocimm.bsky.social · May 28

Dive into cutting-edge innate immunity & inflammation science at our event on September 11!

From immune cell roles to inflammasome signalling, discover advances shaping clinical care.

📆Abstract deadline: 15 July
🐦Early bird registration ends: 27 August

🔗 bit.ly/43q9x9r

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Reposted by Proteases and Innate immunity lab @ York

British Society for Immunology @britsocimm.bsky.social · Jun 18

Congratulations to the winner of the 2025 BSI Outstanding Leadership Award, sponsored by @ceijournal.bsky.social … Professor Clare Bryant, @clarebryant.bsky.social

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · May 28

Interested in innate immunity and inflammation? Join us in September for a great meeting! Superb lineup of speaker and lots of opportunities for Ecrs to present!

British Society for Immunology @britsocimm.bsky.social · May 28

Dive into cutting-edge innate immunity & inflammation science at our event on September 11!

From immune cell roles to inflammasome signalling, discover advances shaping clinical care.

📆Abstract deadline: 15 July
🐦Early bird registration ends: 27 August

🔗 bit.ly/43q9x9r

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Reposted by Proteases and Innate immunity lab @ York

Rebsamen Lab @UNIL @rebsamenlab.bsky.social · May 1

Interested in #InnateImmunity ? Register now to secure your spot — abstracts can be submitted later!
More info: wp.unil.ch/immunobiolog...

#ImmunoSky

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · May 1

Great work by the @inflammasomelab.bsky.social @s-burgener.bsky.social and colleagues showing in vivo the importance of caspase-1 inactivation in controlling inflammation! Impressive amount of work behind it, glad to see this out!
www.biorxiv.org/content/10.1...

Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases

Signal shutdown mechanisms must exist to silence the potent inflammatory programs initiated by the caspase-1 (CASP1) protease, to allow inflammation to resolve and reinstate tissue homeostasis. It is ...

www.biorxiv.org

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Reposted by Proteases and Innate immunity lab @ York

Dimitris Lagos @dimitrislagos.bsky.social · Apr 22

We have a 3-year PDRA post in Cancer Immunogenomics. Ideal to use and strengthen your bioinformatics skills to discover how cancer transcriptome quirks shape immunotherapy outcomes. Funded by @cancerresearchuk.org. It’ll be fun!
jobs.york.ac.uk/vacancy/rese...
@hyms.ac.uk
@ybri-uoy.bsky.social

Jobs - The University of York

jobs.york.ac.uk

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Reposted by Proteases and Innate immunity lab @ York

Eva Frickel @frickellab.bsky.social · Apr 13

🔥 Open postdoc position in human inflammation-driven control of infection! 🔥
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)

Please share!

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Gunnar N. Schroeder @gunnarns.bsky.social · Mar 11

Funded 4-year #PhD in the exciting BBSRC NILAB program. @wwiem-qub.bsky.social

Receive multidisciplinary training, develop #infection models and #AI image analysis to reveal bacterial & viral disease mechanisms & discover new antimicrobials. Fight #AMR

Get in touch!
Details: tinyurl.com/e5k6ptua

Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Queen’s Universit...

PhD Project - Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Que...

tinyurl.com

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Proteases and Innate immunity lab @ York @protinnimmunity.bsky.social · Mar 8

Great work Jelena and team! well-done!

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Reposted by Proteases and Innate immunity lab @ York

JelenaBezbradicaLab @jelenalab.bsky.social · Mar 7

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...

TBK1 and IKKε prevent premature cell death by limiting the activity of both RIPK1 and NLRP3 death pathways

TBK1 and IKKe prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.

www.science.org

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uofytechs.bsky.social @uofytechs.bsky.social · Mar 5

#job 🚨for a laboratory technician in the Wright group within dept. Biology/HYMS and @ybri-uoy.bsky.social to work on creating genome-scale arrays of human cell surface receptors to discover new host-pathogen interactions. Apply by 20/3/2025: jobs.york.ac.uk/vacancy/labo...

Jobs - The University of York

jobs.york.ac.uk

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Reposted by Proteases and Innate immunity lab @ York

uofytechs.bsky.social @uofytechs.bsky.social · Mar 7

#job - INTERNAL candidates only. Technician in dept. Biology in @billgrey.bsky.social lab studying how the proteome evolves from healthy haematopoietic stem cell to malignant leukaemic stem cell in vivo. Apply by 12/3/25 jobs.york.ac.uk/internal/vac...

Jobs - The University of York

jobs.york.ac.uk

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