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Rubén González

@rubengonzalez.bsky.social

1.2K followers 1.3K following 20 posts

Viral Infections and Virus Evolution. A happy postdoctoral researcher at @salehlabparis.bsky.social, Institut Pasteur (Paris, France). https://gonzalezrvirus.com

gonzalezrvirus.com

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Rubén González @rubengonzalez.bsky.social · Mar 14

In my first Drosophila study at @salehlabparis.bsky.social, we found that:

1. Enteric viral infections accelerate aging.
2. Even if the infection is cleared, aging process remains triggered.
3. Accelerated aging correlates with reduced lifespan.

📑Preprint: www.biorxiv.org/content/10.1...

A cute aged fly, despite my mom thinking it’s a bee.

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Reposted by Rubén González

Junior European Drosophila Investigators @fly-jedi.bsky.social · 12d

Dear JEDIs,
as we are self-organizing using the #EDRC as a nucleator we decided it is time for a JEDI database to boost our network! If you identify as a JEDI, please contact us here or send a mail to [email protected] to be added to our database.
#Drosophila
@fly-eds.bsky.social

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Reposted by Rubén González

Kenichi Tsuda @kenichitsuda.bsky.social · 29d

Cheaper defense first, costly one later.
This makes sense.

journals.plos.org/plosbiology/...

Plants respond to herbivory through sequential induction of cheaper defenses before more costly ones

Plants encounter natural threats of varying intensity and respond by activating multiple defense traits. This study of six defense traits in Ambrosia artemisiifolia reveals that when attacked by insec...

journals.plos.org

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Sarah Merkling @merklinglab.bsky.social · Sep 8

Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...

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Reposted by Rubén González

Michael Rera @michaelrera.bsky.social · Sep 3

if you have your team and grants, not forget to support @flybase.bsky.social www.philanthropy.cam.ac.uk/give-to-camb...
meanwhile, we need to think longterm and protect this data, dl it, share it
portal.datarescueproject.org/datasets/fly...

FlyBase

Links to public data archived through combined efforts and coordinated by the Data Rescue Project.

portal.datarescueproject.org

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Reposted by Rubén González

José Cerca @naturalselection.bsky.social · Aug 19

The 2025-26 Eco-Evo job list is out. Good luck to those applying!

docs.google.com/spreadsheets...

ecoevojobs.net 2025-26

docs.google.com

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Flo Débarre @flodebarre.bsky.social · Aug 18

This week, the capital of Evolution is Barcelona!
Over 1900 evolutionary biologists are gathering for the biennial meeting of the European Society for Evolutionary Biology, coorganised with its Spanish sister #ESEB2025.
Over 540 of us are on Bluesky! You can use these starter packs to connect: 1/n

Photo of the welcome address at ESEB2025

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PLOS Biology @plosbiology.org · Aug 12

Forecasting the effects of #epidemics is complicated by a population’s pathogen exposure history. @pfvale.bsky.social @chadisaadroy.bsky.social & Mike Boots argue for the use of experimental #DiseaseEcology to better understand the consequences of variations in #infection history 🧪
plos.io/4mdDVvW

The ghost of infections past: Accounting for heterogeneity in individual infection history improves accuracy in epidemic forecasting

Variable pathogen exposure history contributes to individual immune differences, complicating epidemic forecasting. This Essay argues that experimental disease ecology can offer powerful tools and app...

plos.io

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Jorge Hernández-García @jorgehg.bsky.social · Jul 22

We've tried to gather and unite the streptophyte algae community all around the world to join forces and develop tools and methods for these critters. Learn more about it on @currentbiology.bsky.social!
With @jandevries.bsky.social, @dolfweijers.bsky.social, and (many) others!

tinyurl.com/29n4zwen

A roadmap to developing unified streptophyte algal model systems

Carrillo-Carrasco and colleagues highlight the importance of the establishment of streptophyte algal model systems and the community efforts towards this goal.

www.cell.com

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Mark A. Hanson @hansonmark.bsky.social · Jul 10

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?

That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience

A 🧵 1/n

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François Leulier @francoisleulier.bsky.social · Apr 21

Anyone pushing forward a « microbiome and beyond » WS proposal, that would be an awesome topic… 😉

EDRC2025 @edrc2025.bsky.social · Apr 7

📣The #EDRC2025 will select proposals for six workshops, each with up to nine speakers (12 minutes presentations + 3 minutes Q/A). If you are interested in hosting a workshop, please send a one-page proposal to [email protected] by May 5, 2025 🧪🪰

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SalehLab @salehlabparis.bsky.social · Apr 10

Thrilled to receive @anrs-mie.bsky.social grant with @lambrechtslab.bsky.social & @retrogenomics.bsky.social! Making mosquitoes intolerant to arboviruses. Thanks @pasteur.fr, @inserm.fr & @cnrs.fr for support. Exciting times for #ARBORETRO project! Stay tunned.

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Pedro Vale @pfvale.bsky.social · Apr 9

Hi #Drosophila folk: I'm advertising a 2-year #Postdoc, funded by a BBSRC grant on the genetic and immune determinants and evolutionary constraints underlying extreme pathogen transmission phenotypes. Deadline 29 April, details in the link below, or feel free to email:
www.jobs.ac.uk/job/DMQ231/p...

Postdoctoral Research Associate at The University of Edinburgh

Apply now for the Postdoctoral Research Associate role on jobs.ac.uk - the leading job board for higher education jobs. View details.

www.jobs.ac.uk

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Rubén González @rubengonzalez.bsky.social · Apr 4

Amazing new tools for studying fly immunity!! Fantastic work

Mark A. Hanson @hansonmark.bsky.social · Apr 1

Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.

Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?

1/n 🧵

Layers of immunity: Deconstructing the Drosophila effector response

The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...

www.biorxiv.org

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Carolina Monzó @carolinamonzo.bsky.social · Mar 28

It's finally out!!!! Our review on long-reads transcriptomics was published in @natrevgenet.bsky.social!! You can have a look at the paper here rdcu.be/efugl! We hope you like it 😀

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Michael Rera @michaelrera.bsky.social · Mar 25

A friend sends me that picture and I'm very happy of my 14 years fighting to get this model accepted within the ageing research community.
A serendipitous discovery I made that really changes everything !

A picture of neo (matrix) subtitled "this is how I feel now" under a sentence saying "ok, I know what a Smurf phenotype is now"

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Sarah Ashley @sarah-ashley.bsky.social · Mar 21

A new way to conduct GWAS meta-analysis? Preprint shows Genomic Network Analysis can be used to identify conditionally independent associations between traits, controlling for shared genetic signals. Also enables multi-level biological analysis within the framework to probe underlying aetiology🧬🖥️

Stephen Turner @stephenturner.us · Mar 20

Genomic network analysis characterizes genetic architecture and identifies trait-specific biology www.medrxiv.org/content/10.1... 🧬🖥️🧪

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thetranscendedman @atranscendedman.bsky.social · Mar 20

Scientists in China developed SCLIMS, a tool that links metabolism to oxidative stress at the single-cell level.

They found that metabolic differences predict cell fate under stress and that key metabolites can extend lifespan in C. elegans.

www.nature.com/articles/s41...

Integrative single-cell metabolomics and phenotypic profiling reveals metabolic heterogeneity of cellular oxidation and senescence - Nature Communications

Integrated analysis of metabolome and oxidative stress at single-cell level is challenging. Here, the authors develop SCLIMS, enabling simultaneous profiling of metabolome and oxidative stress levels ...

www.nature.com

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Buck Samuel 🪱🦠🧬🔬 @microbeminded.bsky.social · Nov 12

To all the newskies, welcome! #HiSciSky

As #firstgen PI at BCM in Houston, my lab studies how the #microbiome alters host physiology using genetics & genomics in #Celegans. Our lens is #BasicResearch, but aim to promote human health on earth and beyond.

🧪🖥️🧬 #AcademicSky #MicroSky 1/3

Cartoon illustration of C. elegans nematodes and their microbiome. By Adrien Assié.

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European Drosophila Society @fly-eds.bsky.social · Mar 18

European Drosophila Board election call for nominations. Join the EDB to represent and support Drosophila research in Europe! Five representatives will be elected for different regions. Check our election page for details:
europeandrosophilasociety.org/european-dro...
#Drosophila, #EDRC2025

A fly voting in the European Drosophila Board election

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Harmit Singh Malik @harmitmalik.bsky.social · Mar 19

Please consider nominating deserving colleagues (including yourselves) who would be excellent candidates for five open positions on the Council, including Nominations for President-elect, Secretary, Treasurer, and 2 Councilors.

Please share widely!

@official-smbe.bsky.social

Dear SMBE Members,

I am writing to solicit nominations for SMBE President-Elect, Secretary, Treasurer and 2 Councilors whose terms will begin on January 1, 2026. Each of these positions is for a duration of three years.

Council members play important roles in guiding the development of the society, soliciting and implementing programs that support our members, while enriching opportunities for young scientists from around the world. They also have a role in overseeing our two excellent journals (MBE and GBE) as well as our annual meeting, regional meetings, and satellite meetings.

Nominations will be reviewed by the nominations committee who will then put forward a slate of two candidates for each position for vote by the SMBE membership. Past and current council members are listed HERE.

Nominations (self-nominations are welcome) should consist of a brief statement in support of your suggestion (why this nomination, what the nominee can bring to SMBE, work subject, other biographical information). For Presidential nominees please include previous involvement with SMBE.

We ask the nominators to confirm explicitly that the person they are nominating has already confirmed their willingness to run for office.

Please send your nominations to Harmit Malik <hsmalik@fredhutch.org> AND to Emmanuelle Lerat <secretary.smbe@gmail.com> by April 18, 2025.

We look forward to hearing from you!

Sincerely yours,
Emmanuelle Lerat
Secretary of SMBE, on behalf of the Nominations Committee*

*The Nominations Committee is composed as follows:
Harmit S Malik (Chair) USA.
Xuming Zhou, China.
Mary O'Connell, UK.
Nicolas Galtier, France.
Deepa Agashe, India.
Emmanuelle Lerat (ex officio), France.

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PLOS Biology @plosbiology.org · Mar 19

Genome sequencing & single-cell transcriptomics continue to produce findings that challenge the idea that #cancer is purely a genetic disease. This Essay delves into #omics data that questions the somatic mutation theory & presents alternative theories based on GRNs & tissue fields.🧪
plos.io/3DRtAEW

A figure depicting the concept of cancer attractor states within Waddington's landscape, and how gene regulatory network dynamics influence these states.

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Reposted by Rubén González

Théo Maire @theomaire.bsky.social · Jan 27

Thrilled to share 'BuzzWatch', my post-doc work with Felix Hol and @lambrechtslab.bsky.social

➡️Filming mosquitoes in a cage with a €15 camera but for 700h(1month) revealed fascinating insights into their behavior⌛🦟🎥⏳

preprint🔍 doi.org/10.1101/2025...
DIY guide 🛠️ theomaire.github.io/buzzwatch
🧵⬇️

BuzzWatch: uncovering multi-scale temporal patterns in mosquito behavior through continuous long-term monitoring

Understanding the temporal dynamics of mosquito behavior is essential for developing effective interventions against pathogen transmission. However, limited knowledge exists about the environmental, p...

doi.org

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Maya Voichek @mayavoichek.bsky.social · Mar 17

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇

Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte

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Reposted by Rubén González

Michael Rera @michaelrera.bsky.social · Feb 27

I am happy to announce with @hanli-pasteur.bsky.social that we'll organise a summer school titled "Senescence from Cell Cultures to Humans through Model Organisms" in Paris, Fr on June 23-24, 2025
Aimed at 2nd and 3rd year PhD student + postdocs
Submit your provisional project tinyurl.com/2uhfzxbp

flyer of the event with the name of confirmed trainers Cléo Bishop, Eric Boulanger, Manuel Collado and Bill Keyes,
Deadline for application May 30th 2025,

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EMBO @embo.org · Feb 12

Hello everyone on Bluesky! 🧪

We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond.

Read more: www.embo.org/about-embo/m...

Text: EMBO is on Bluesky.
Butterfly icon with text: @embo.org

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