whaaaaat how unexpected!

This analysis remains undefeated.

hi science bluesky 🧪 i have a question. has anyone shown if sgRNAs are susceptible to degradation by RNases when they're bound to the Cas9 protein? I know they're very unstable when unbound, but I can't seem to find evidence of their stability in the RNP complex. any help is appreciated!!

Hey remember when the CDC dropped 6 of the 8 foodborne illnesses from the nationwide monitoring system in July and one of them was listeria? Mentioning for no particular reason www.nbcnews.com/health/healt...

An unprecedented violation of our civic and Constitutional traditions. Calling every military leader in the world back to the U.S. to hear a wildly inappropriate partisan campaign speech followed by a fascist call to use the military against Americans.

This is the official communication from the FDA to physicians on acetaminophen use in pregnancy.
- They acknowledge the lack of a causal link with autism
- Essentially tell physicians to keep doing what we've been doing anyway
It's very different from the press conference.
Pass it on.

Reminder: a large (2.5M+) sibling control study found "no evidence of increased risk of autism, ADHD, or intellectual disability associated with acetaminophen use". Precisely the kind of data that requires serious consideration before declaring mission accomplished.

jamanetwork.com/journals/jam...

made this

Universities. Rural hospitals. Tech companies. Several sectors are going to be profoundly hurt by this. Not to mention the chaos of the moment as current H1-B owners scramble to get back to the U.S., cancel travel, etc. due to the uncertainty. An absolute mess. As intended.

"arise against the backdrop of documented performance concerns" is crazy lmfao

the epistemic breakdown of factual reality in this political media environment has been so harmful

when facts genuinely favor the left, the right will simply deny the facts or call the messenger biased, without any refutation

reality will always be biased against a movement detached from reality

We're witnessing the most aggressive, fanatical crackdown on free speech in my lifetime. The speed and breadth of government censorship and private sector and nonprofit capitulation has been astonishing. As has the lack of urgency/silence from people who've long claimed to care about this stuff.

Political violence is abhorrent. I have not celebrated Kirk's death.

But Newsom calling for his followers to "continue Charlie Kirk's work," someone who praised stoning gay people as "god's perfect law," who called for men to "take care of" trans people like they did in the 50s and 60s, is not it.

Glenn Beck’s media outlet The Blaze just gave an interview last month to the person who killed the politicians in Minnesota

political violence is a terrible scourge that has claimed victims from both parties

the way some people are just itching to treat this as a reichstag fire moment to enable a dictatorship is extremely scary and a good reminder that political violence is a threat to the very core of liberal democracy

Hot off the press: We can provide for the first time a systematic attribution of recent #heatwaves to the emissions of #carbon_majors. Essential new #Nature article coordinated by @yannquilcaille.bsky.social at @ethz.ch, with numerous contributors @usyseth.bsky.social:
www.nature.com/articles/s41...

Here is a word cloud of the words that were missing from the noncompetitive renewal awards but had been present in the parent award.

3/4

another note but this is so clearly biased towards the center because it is presented as an upside down parabola, leading viewers to automatically assume the local maximum is the most reliable and accurate news source. this was DIRECTLY taught to us in high school when shown this chart.

screaming at the top of my lungs that reporting facts requires you to select the facts to report based on a conscious or unconscious bias!!!! only trust facts when put in the direct context!!!!!!

i remember seeing this chart in high school as a fun lesson"both sides are extreme, trust the center" and looking back now i grow weary

one of the great conservative moves over the past decade has been to make themselves so unpleasant that their own family members are forced to cut them off, and then use that fact to argue that *liberals* are too uncivil

if you'd rather save face than run a successful country, you're not cut out for politics

I will remind folks those images of Nazi book burnings aren't burning just any books. They're burning the library of Magnus Hirschfeld; a gay, Jewish doctor who created an institute dedicated to LGBTQ sex education and healthcare. And a man who pioneered gender affirming care surgeries.

i don't think gavin newsom is our only choice in resisting fascism. he's just the one making the biggest spectacle of gesturing in that direction