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Reposted by SCALE - SubCellular Architecture of LifE

Aaron Klausnitzer @aklausnitzer.bsky.social · 15d

Proud that our work is online now in @jacs.acspublications.org 🎉 A big thanks to everyone involved in this project! If you are interested have a read:

doi.org/10.1021/jacs...

Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB2FGC Complex

The outer membrane of Gram-negative bacteria is coated with lipopolysaccharide (LPS). The Lpt system generates membrane asymmetry by transporting LPS from the inner to the outer membrane. Transport be...

doi.org

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GBM (Gesellschaft für Biochemie und Molekularbiologie) @gbmev.bsky.social · 20d

GBM Compact Focus on Condensate Biology is opened by Edward Lemke. Looking forward to a great meeting!

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 20d

This morning we travelled into the fascinating world of neurons and synapses with @erin-schuman.bsky.social. We learnt how protein synthesis takes place in neuronal dendrites. 🧠

@mpibrain.bsky.social

#imprs_cbp #gradschool #brain

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 20d

We followed with a day packed with CryoEM! We heard about the cryoEM from Werner Kühlbrandt, STEM-EELs from Bonnie Murphy and CryoET from Martin Beck.

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 23d

We're very excited to welcome the new generation of #IMPRS students during our Symposium on Cellular Biophysics 🧪 This morning, we heard spokespersons Volker Dötsch and Martin Beck, and coordinator Pamela Ornelas, introduce the doctoral program to the new students!
#imprs_cbp #biophysics #gradschool

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 23d

We had a great start of the #IMPRS Symposium on Cellular Biophysics to welcome our new students. Thank you for your fascinating talks Michaela Müller-McNicoll, Bernhard Hampölz and Christian Münch 👏

#imprs_cbp #phd #biophysics

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Michaela Müller-McNicoll @mixmue.bsky.social · Sep 6

I am sooo excited. Starting tomorrow the next edition of the fabulous #emboiclip2 course begins. @koenig-lab.bsky.social, @zarnack-group.bsky.social, moi & Elias Bechara will present 3 improvements to the method, a semi-automated workflow for data analysis and an exciting line up of speakers. Ready?

Michaela Müller-McNicoll @mixmue.bsky.social · Mar 13

Apply to our #EMBOiCLIP2 course in beautiful Genova this fall. Learn the latest version of the protocol, meet the experts in the field, analyze your own data and get to know fellow RNA aficionados.
meetings.embo.org/event/25-icl...

iCLIP2, mapping protein-RNA interactions: from A to Z

RNA is increasingly recognized as a key therapeutic target , driving the development of RNA-based therapeutics for a broad spectrum of diseases. RNA-binding proteins (RBPs) play a fundamental ro…

meetings.embo.org

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Goethe-Universität Frankfurt @goetheuni.bsky.social · Sep 8

Congratulations! 🎉

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Sep 3

Celebrate with us on Sept 15, 1 PM & hear his talk: "Illuminating Biosynthetic Dark Matter: Unlocking Hidden Pathways to Discover Natural Products with Therapeutic Promise"
👉 goethe-university-frankfurt.de/150458316/Ea...
🔍 Helfrich’s research: helfrichlab.com

goethe-university-frankfurt.de

SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Sep 3

🎉 We congratulate Prof. Dr. Eric Helfrich on nomination for the Paul Ehrlich & Ludwig Darmstaedter Early Career Award 2026! 🔬👏

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IMPRS on Cellular Biophysics @imprs-cbp.bsky.social · Aug 30

We’re looking forward to the IMPRS-CBP Symposium on Cellular Biophysics at the @mpibp.bsky.social ! Join us on Sept 15–22 for a week+ of talks from our faculty as we welcome our new students! 🧑‍🎓Learn more here: imprs-cbp.mpg.de/symposium-on...

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SFB 1551 - Collaborative Research Centre 1551 @sfb1551.bsky.social · Aug 22

Fresh in Nature Communications: a big update from the international biocondensate community featuring SFB1551 spokespersons @dormannlab.bsky.social and @lemkelab.bsky.social
Read more 👉 www.nature.com/articles/s41...
Congrats to all authors!

Current practices in the study of biomolecular condensates: a community comment - Nature Communications

The realization that the cell is abundantly compartmentalized into biomolecular condensates has opened new opportunities for understanding the physics and chemistry underlying many cellular processes1...

www.nature.com

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Max Planck Institute of Biophysics @mpibp.bsky.social · Aug 18

We’re hosting the @embo.org Practical Course on In-situ structural biology by CryoFIB and CryoET in April 2026! 🧬❄️ You can expect hands-on training, cutting-edge methods, and a chance to work alongside leading experts in structural biology. 🔗 Apply by Dec 8, 2025: meetings.embo.org/event/26-in-...

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Aug 19

Congratulations Jenny, Martin and Bernhard 🥳!

Jenny Sachweh @jennysachweh.bsky.social · Aug 18

My PhD paper is in press @cellpress.bsky.social and now online: www.sciencedirect.com/science/arti...!

Contents: weird #NPCs in yeast and flies, #CLEM, in situ #cryoET and more!

Made possible by the amazing @becklab.bsky.social team at @mpibp.bsky.social and collaborators! #TeamTomo

The small GTPase Ran defines nuclear pore complex asymmetry

Nuclear pore complexes (NPCs) bridge across the nuclear envelope and mediate nucleocytoplasmic exchange. They consist of hundreds of nucleoporin build…

www.sciencedirect.com

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Goethe-Universität Frankfurt @goetheuni.bsky.social · Aug 19

🚀 Spotlight on early #career #science! On Sept 15, six outstanding young #researchers present their work at the Paul Ehrlich & Ludwig Darmstaedter Early Career Award 2026 – #Symposium in Frankfurt. Don’t miss it! | 🔗Register now lmy.de/MzPjd #GoetheUni

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Human Frontier Science Program @hfspo.bsky.social · Aug 18

🧪 Who is Erin M. Schuman, winner of the 2026 HFSP Nakasone Award?

She uncovered that synapses — the brain’s communication hubs — can make their own proteins, rewriting how we think memories form.

Discover her research 👉zurl.co/niEzX

#HFSPNakasoneAward #sts

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SFB 1551 - Collaborative Research Centre 1551 @sfb1551.bsky.social · Aug 14

🎉 Congrats to @kgaurav.bsky.social, Lukas Stelzl & @reneketting.bsky.social (SFB1551) on their new Biophysical Journal paper! #MUT16 #PhaseSeparation #MutatorFoci #SmallRNA #GeneRegulation #Celegans #ProteinAssembly #RNAResearch #MultiscaleSimulations Great teamwork👏👏👏 www.cell.com/biophysj/ful....

Multi-scale Simulations of MUT-16 Scaffold Protein Phase Separation and Client Recognition

Phase separation of proteins plays a critical role in cellular organisation. How phase separated protein condensates underpin biological function and how condensates achieve specificity remain elusive...

www.cell.com

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Kurianlab @kurianlab.bsky.social · Aug 7

*Seminar Alert*

Prof. Sergej Djuranovic, PhD
Brown University, USA

Date: 02.09.2025. 15:00

Venue: Faculty of Medicine, Goethe University, Seminar room 4, Haus 23 (S23-4)

@djuranoviclab.bsky.social
@cpi-exstra.bsky.social
@scale-cluster-ffm.bsky.social
@goetheuni.bsky.social

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Aug 4

Many congratulations!

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Max Planck Institute for Brain Research @mpibrain.bsky.social · Aug 1

🚛 Ribosomes on the road! New research from the Schuman Lab @mpibrain.bsky.social shows neurons can locally assemble ribosomes - far from the nucleus and close to synapses. A big shift from textbook biology! 📚🧬🔗 bit.ly/3GUJKPv #Neuroscience #CellBiology #Ribosomes

Ribosomes On the Road: Neurons Assemble Protein Factories Far from the Nucleus

New study shows ribosome biogenesis can occur within neuronal branches, challenging traditional textbook biology.

bit.ly

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SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Jul 28

🔬 This research uncovers how the splicing factor SRSF5 helps coordinate the interaction between two neighboring nuclear structures—nuclear speckles (NS) and paraspeckles (PS)—particularly during cellular stress.

SCALE - SubCellular Architecture of LifE @scale-cluster-ffm.bsky.social · Jul 28

👏Congratulations to @mixmue.bsky.social, @heilemannlab.bsky.social, and all co-authors on their recent publication in Nucleic Acids Research!
Proud to see this work arise from the collaborative efforts of SCALE faculty, including Stefan Müller and Dorothee Dormann.
academic.oup.com/nar/article/...

Rapid depletion and super-resolution microscopy reveal dual roles of SRSF5 in coordinating nuclear speckle–paraspeckle crosstalk during cellular stress

Abstract. Nuclear speckles (NS) and paraspeckles (PS) are adjacent yet distinct nuclear condensates that undergo stress-induced reorganization. Here, we id

academic.oup.com

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ProLOEWE @proloewe.bsky.social · Jul 18

Prof. Franziska Matthäus in der🆕Ausgabe des unireport @goetheuni.bsky.social ehem. 🗣️von➡️LOEWE-CMMS @fias.bsky.social zu »Critical Computational Literacy @ GU Future Skills and Beyond« einem🆕 Lehrangebot zu KI & Co➡️ www.unireport.info/176087817/un... mehr zu Matthäus➡️ proloewe.de/de/persoenli...

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PLOS Biology @plosbiology.org · Jul 11

#ER - #membrane contact sites are often distorted by existing labeling methods. @steveroyle.bsky.social &co present an inducible labeling system (LaBeRling) using #LaminB receptor to fluorescently tag ER-membrane contact sites in live cells, preserving morphology @plosbiology.org 🧪 plos.io/4lv6gxu

Left: LaBeRling contact sites between the plasma membrane (green) and the endoplasmic reticulum (magenta). Contacts are highlighted in blue using LBR. Image created by Laura Downie. Right: 3D render of a membrane contact site (orange) between a mitochondrion (pink) and the ER (green contours). Image created by Stephen Royle.

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Goethe-Universität Frankfurt @goetheuni.bsky.social · Jul 17

👆🏼 @tuda.bsky.social

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