The 'sparks' of life! Our latest work on the role of #calcium dynamics in the early #embryo. 🎇🔬🐁

@idrm.ox.ac.uk @oxforddpag.bsky.social @srinivas-lab.bsky.social #lightsheetmicroscopy #GCAMP

During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4

#OnThisDay in 1858, a seminal journal article comprised of papers by Alfred Russel Wallace FRS and Charles Darwin FRS on the theory of evolution by natural selection was published by the Linnean Society, the first public announcement of the theory of evolution. bit.ly/3k8fq4u

*TODAY Wed 4 June 15:00 BST (UTC+1)*

Development presents... webinar, celebrating the winners of the @bsdb.bsky.social postdoc poster prize from the Biologists @ 100 conference. We'll hear from @giuliapaci.bsky.social and @shifaant.bsky.social

Register here: us02web.zoom.us/webinar/regi...

Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social.

journals.biologists.com/dev/article/...

@idrm.ox.ac.uk Funded by the @thebhf.bsky.social

*This Wed 4 June 15:00 BST* Register to attend our next Development presents... webinar, celebrating the winners of the @bsdb.bsky.social‬ postdoc poster prize from the Biologists @ 100 conference. We'll hear from @giuliapaci.bsky.social‬ and @shifaant.bsky.social‬
us02web.zoom.us/webinar/regi...

Register now to attend our #DevPres webinar next week, featuring the winners of the @bsdb.bsky.social poster prize, @shifaant.bsky.social and @giuliapaci.bsky.social, and chaired by Abigail Tucker.

4 June at 15:00 BST

us02web.zoom.us/webinar/regi...

Visa costs will limit Britain's ability to court those who may seek to leave the U.S. after Trump's administration cut funding for universities and research bodies, says Professor Alison Noble FRS, Foreign Secretary of the Royal Society: www.reuters.com/world/uk/hig...

This is the head of a chicken embryo after 16 days of development, imaged with light sheet microscopy 🐣🔬🧪

The sun is shining over the beautiful city of Liverpool for @biologists.bsky.social ‘s Centenary Meeting ( #biologists100)

Very happy to share our work on lymphatic endothelial cell specification, which was published in Nature Cardiovascular Research this week.

✨Excited to share our work revisiting the developmental origins of mammalian lymphatic endothelial cells.✨

A summary of our key findings using scRNA-seq, snMultiome-seq and imaging to show the direct specification of mesenchymal progenitors to LECs🧵 #blutorial #blabstract

tinyurl.com/LECspec

Excited to have provided the cover images for the new Kaufman's Atlas of Mouse Development Supplement (edited by Gillian Morriss-Kay & Shankar Srinivas) – the go-to reference resource for all mammalian developmental biologists.

Have always been fascinated about these elusive giants–the beaked whales. Until now nothing was known about this extant species; known from only seven records and have never been seen alive at sea. Turns out it has a nine-chambered stomach and vestigial teeth! www.doc.govt.nz/news/media-r...

Happy to share our latest review by @shifaant.bsky.social with @cwhanna.bsky.social. A detailed look at extraembryonic tissues – the 'other half' of the conceptus.

www.nature.com/articles/s41... @natrevmcb.bsky.social

Beautifully written essay by @jbwallingford.bsky.social that every developmental biologist should read. aeon.co/essays/after...

Nice to see our latest review published in
@natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social

www.nature.com/articles/s41...

A scenic walk to work this morning. Oxford, Oxfordshire.

Happy to have the Srinivas lab on Bluesky!

Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...

Feeling Festive! Very happy to share our new bioRχiv pre-print – investigating the role of calcium signalling in the early mouse embryo:
www.biorxiv.org/content/10.1...

Calcium signalling is required for anterior patterning in the mouse embryo https://www.biorxiv.org/content/10.1101/2024.11.14.623160v1