🔞 The Northstar✨ System
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supuhstar.com
🔞 The Northstar✨ System
@supuhstar.com
88 followers 180 following 380 posts
'91 • 🔞🏳️‍⚧️Ⓐ✊🏽∞&θ∆ • 우리는 한국어 배우기 중이어요 • Integrated DID system • >35 headmates • We are many & proud & healthy • Info: Supuhstar.com
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🔞 The Northstar✨ System @supuhstar.com · Feb 16
Here's what that SHOULD say
Reposted by 🔞 The Northstar✨ System
yuukidesu9.bsky.social
@jtfg.dev core
big and fluffy birb
curanull.bsky.social CuraNull @curanull.bsky.social · 1d
Just realized I get to post this one too!
January 9, 2026 at 6:27 PM
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sleepingirl.info
After dissatisfaction with the restaurants around here, I have finally sated my craving for Japanese curry.

Secret ingredients: applesauce and cocoa powder
January 7, 2026 at 8:33 PM
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lovebuns.bsky.social
This has been shortened a lot due to the BlueSky character limit 🥹

🐰 “Just a rabbit” brings out what’s good in me, and diverts my thoughts away from myself and the worries of the day.

~ Author unknown, and thanks to our Snowbelle for the cute picture. ❤🐇❤
Snowbelle, Himalayan Dwarf rabbit (white with ruby eyes, black nose, ears and paws) with an open mouth. The statement reads "So out of all the bunnies our there...you picked me?
January 8, 2026 at 2:55 PM
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nancycomics.bsky.social
Nancy By Ernie Bushmiller
January 02,1947
NANCY BY ERNIE BUSHMILLER P1- NANCY IS SLIDING BACKWARDS DOWN THE STAIR BANISTER, HER AUNT FRITZI IS VERY UPSET BY NANCY SLIDING DOWN THE BANISTER FRITZI: NANCY - - - GO RIGHT BACK UP AND COME DOWN LIKE A LADY P2-NANCY GOES UP THE STAIRS P3- NANCY SLIDES DOWN THE BANISTER, THIS TIME SHE IS SITTING SIDEWAYS , ONE HAND ON HER HIP, THE OTHER HAND BEHIND HER HEAD, SHE DESCENDS DOWN DOWN THE BANISTER WITH AN AIR OF COOLNESS.
January 2, 2026 at 9:25 PM
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queenrayna1337.bsky.social
January 1, 2026 at 1:01 PM
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sailorrooscout.bsky.social
GOOD NEWS! A group of patients with an otherwise incurable form of T‑cell leukemia have seen their cancer driven into REMISSION by an innovative immune therapy known as BE-CAR7. 82% of patients reached deep remission and 64% of patients have now been disease-free and OFF therapy for THREE years.
January 1, 2026 at 5:00 PM
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masonfromtwitter.bsky.social
I did not realize I had my "ask me about free STD partner treatment" pin from work on this jacket lol
If you live in Los Angeles and you have an STI you can get expedited partner therapy which means if you test positive for an STI they can get a dose of medicine for you too without you coming in
December 29, 2025 at 2:15 AM
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katriaraden.bsky.social
when in doubt, draw strawberries!!
acrylic markers on wood
photo of a wooden plaque with a drawing of stylised strawberries on a black background
December 28, 2025 at 11:03 PM
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sailorrooscout.bsky.social
In preclinical models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer’s biomarkers (in HUMAN models as well).
• case.edu/news/new-stu...

The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...

🧪🧵⬇️
Highlights •Severity of Alzheimer's disease (AD) correlates with NAD+ homeostasis dysregulation •Preserving brain NAD+ homeostasis prevents AD in mice • Restoring brain NAD+ homeostasis reverses advanced AD in mice • Multiomics across human and mouse AD brain identifies nodes for human AD reversal Summary Alzheimer's has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain's energy supply help drive the disease-and restoring that balance can reverse damage, even in advanced cases. In mouse models, treatment repaired brain pathology, restored cognitive function, and normalized Alzheimer's biomarkers. The results offer fresh hope that recovery may be possible. Abstract Alzheimer's disease (AD) is traditionally considered irreversible. Here, however, we provide proof of principle for therapeutic reversibility of advanced AD. In advanced disease amyloid-driven 5xFAD mice, treatment with P7C3-A20, which restores nicotinamide adenine dinucleotide (NAD+) homeostasis, reverses tau phosphorylation, blood-brain barrier deterioration, oxidative stress, DNA damage, and neuroinflammation and enhances hippocampal neurogenesis and synaptic plasticity, resulting in full cognitive recovery and reduction of plasma levels of the clinical AD biomarker p-tau217. P7C3-A20 also reverses advanced disease in tau-driven PS19 mice and protects human brain microvascular endothelial cells from oxidative stress. In humans and mice, pathology severity correlates with disruption of brain NAD+ homeostasis, and the brains of nondemented people with Alzheimer's neuropathology exhibit gene expression patterns suggestive of preserved NAD+ homeostasis. Forty-six proteins aberrantly expressed in advanced 5xFAD mouse brain and normalized by P7C3-A20 show similar alterations in human AD brain, revealing targets with potential for optimizing translation to patient care. Graphical Abstract (CREDIT: Cell Reports Medicine)
December 28, 2025 at 5:03 PM
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sailorrooscout.bsky.social
GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages.
December 28, 2025 at 5:00 PM
supuhstar.com
Proprietary software is so stupid…
December 25, 2025 at 8:13 PM
supuhstar.com
@tangentfoxofficial.bsky.social security is a good idea for you and I will get you some money for it 😘
December 24, 2025 at 4:20 AM
supuhstar.com
Why did you transition? Wrong answers only.

Free Swedish blue shark plushie
tangentfoxofficial.bsky.social TangentFoxOfficial @tangentfoxofficial.bsky.social · 18d
Why did you transition, wrong answers only

There was a two for one special - give up one dick for two boobs!
demon-sushi.com cial | notfun >> ANE26 o.o @demon-sushi.com · 18d
Why did you transition, wrong answers only

i tired of the rattle and clatter of my breasts
December 23, 2025 at 10:02 PM
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gmd3d.bsky.social
Hey artists!! Post some art you made before Bluesky!!
#lightwave3d #startrek phase II Enterprise set against space scenes by @grahamtg.bsky.social 2024
December 22, 2025 at 9:37 PM
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annesmien.bsky.social
This is a watercolour painting of my cat Mia which I did on a postcard for a competition a few years ago. I didn't win! 😐
#cats #kittens #competition #art #watercolours #painting
This was something I did for an art competition some years ago. They had a lot of entrants and they picked the best 100 to display at the art museum. Mine wasn't picked unfortunately.
December 22, 2025 at 7:28 PM
supuhstar.com
Great article, I assume
December 23, 2025 at 5:20 AM
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annihowls.bsky.social
He’s working on his end of year reports
Dominic the grey cockatiel sits at a mini toy laptop looking thoughtful
November 25, 2025 at 6:20 AM
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kyrogue.bsky.social
Super simple ping-pong animation with four unique frames. Gift art for a user on #WaterdogWorld

#WaterDog #WaterDogs #WaterDogArt #Animation #DigitalAnimation #DigitalArt #Procreate
December 18, 2025 at 6:20 PM
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bitshammer.bsky.social
December 18, 2025 at 1:47 PM
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scaribou.bsky.social
My apologies to anyone who has casually asked me what my ideal superpower would be, because I cannot be normal about the answer.

#transfur #tfeveryday
December 17, 2025 at 6:55 PM
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meodai.bsky.social
Trying to combine labels + tooltips
December 16, 2025 at 11:19 AM
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echoampersand.bsky.social
headache
#procreate
December 14, 2025 at 7:14 PM
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echoampersand.bsky.social
I have a move date and plan !!!!

This payment will leave me with $110, including most of the current donated money, so I will stay at my job for one more week to get maybe another hundred dollars.

A new job will take at least 2 weeks so I need help!
#MutualAid #Helpsky
"Dear [echo], Congratulations on accepting Unit #229 in [redacted address ]! You are scheduled for your move-in inspection at [redacted adress] on Thursday, December 18, 2025, at 10:00 a.m. Maintenance will meet you outside the main entrance of the building. Following the inspection, your lease signing will take place at the [redacted agency] offices, on the same day at 10:30 a.m. Please allow approximately 45-60 minutes for the lease-signing appointment. As discussed, you are required to pay the security deposit of $350.00 and the pro-rated December rent of $84.00. Please bring a check or money order made payable to [redacted agency] in the amount of $434.00. Keys to the unit will be provided once payment is received. Your regular monthly rent amount going forward will be $186.00. If you have any questions or need additional information before your appointment, please contact [redacted number]."
December 15, 2025 at 4:58 PM
supuhstar.com
I legitimately cannot understand cis people...
you're telling me that society tells you that you gotta be a certain way because of how you were born and your response is just like
"yea, sounds great to me!"

???????
December 14, 2025 at 10:31 PM