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Yuki Masuo M.D. @yuki-masuo.bsky.social · Sep 5

Our recent paper was highlighted in @natrevrheum.nature.com😊

Original paper: www.science.org/doi/10.1126/...

I forgot to mention this before, but I would like to thank @cnfogg.bsky.social & @hannah-isles.bsky.social for their smooth handling of our paper!

Nature Reviews Rheumatology @natrevrheum.nature.com · Sep 5

New content online:

Two subsets of TPH cells with distinct functions in RA

Nature Reviews Rheumatology, Published online: 05 September 2025; doi:10.1038/s41584-025-01300-2Stem-like and effector-like peripheral helper T cells have distinct functions in rheumatoid arthritis.

bit.ly

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Aug 16

Thank you! I will try 🧵 posts next week:)

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Aug 16

📣Our new paper is out in Science Immunology.

We uncovered how stem-like and effector Tph cells play distinct roles in RA pathogenesis.

🔗https://www.science.org/doi/10.1126/sciimmunol.adt3955

Exciting illustration by @chimomonga.bsky.social depicting cells as robots and dogs🤖🐶

#RA
#Tph

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Reposted by Yuki Masuo M.D.

Seth Thomas Scanlon @immunoeditor.bsky.social · Aug 1

The August issue of #Science #Immunology is out! This week: T peripheral helper cells expressing IGFL2 contribute to rheumatoid #arthritis; vagal TRPV1+ sensory #neurons protect against #influenza virus infection; & transfer of #Tregs alleviates #inflammaging in mice!

wwwscience.org/toc/sciimmun...

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Aug 2

ご紹介ありがとうございます！

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Reposted by Yuki Masuo M.D.

Hiroyuki Yoshitomi @hiro-yoshi-jpn.bsky.social · Aug 2

Our study on immune responses in synovial tissue of patients with rheumatoid arthritis reveals the involvement of an evolutionary novel cytokine IGFL2 in the pathogenesis.

@sciimmunology.bsky.social
doi.org/10.1126/scii...

Human CD4+ T cells regulate peripheral immune responses in rheumatoid arthritis via insulin-like growth factor–like family member 2

IGFL2 is preferentially expressed by TPH cells and influences CD4+ T differentiation and macrophage activation in rheumatoid arthritis.

doi.org

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Aug 2

New paper from our lab published in Science Immunology.
IGFL2, a previously uncharacterized cytokine, is produced by peripheral helper T cells (Tph cells) and regulates local immune response in rheumatoid arthritis.

www.science.org/doi/10.1126/...

Human CD4+ T cells regulate peripheral immune responses in rheumatoid arthritis via insulin-like growth factor–like family member 2

IGFL2 is preferentially expressed by TPH cells and influences CD4+ T differentiation and macrophage activation in rheumatoid arthritis.

www.science.org

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Jul 1

Honored to receive this award last week in Boston. Thank you @focisimmunology.bsky.social @britsocimm.bsky.social for the recognition.

#FOCIS2025

FOCIS - Federation of Clinical Immunology Societies @focisimmunology.bsky.social · Jul 1

FOCIS also wants to congratulate the 2025 recipient of the British Society for Immunology (BSI) Poster Prize Award - Yuki Masuo, MD 👏

#FOCIS2025

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Jul 1

Thank you!!

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Yuki Masuo M.D. @yuki-masuo.bsky.social · May 29

Looking forward to this symposium!

Samuel A. Myers' lab @samyers-lab.bsky.social · May 29

Come join us next week to hear @kuchroolab.bsky.social talk about exciting new work @lji.org

Yuki Masuo M.D. @yuki-masuo.bsky.social · May 3

Recent paper from our lab published in @brain1878.bsky.social
Great example of an in-depth analysis using tissue-derived samples.

Brain @brain1878.bsky.social · Mar 12

By analysing CSF and blood samples from patients with acute neuromyelitis optica, Nishigori et al. identify dominant B cell subsets that differentiate into cells producing pathogenic antibodies within the CNS. buff.ly/JHLGO3g

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Reposted by Yuki Masuo M.D.

Nature @nature.com · Apr 16

Nature research paper: Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease

https://go.nature.com/4ikgYEu

Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease - Nature

After transplantation into the brain of patients with Parkinson’s disease, allogeneic dopaminergic progenitors derived from induced pluripotent stem cells survived, produced dopamine and did not form tumours, therefore suggesting safety and potential clinical benefits for Parkinson’s disease.

go.nature.com

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Apr 5

Thank you for coming all the way to Japan and staying with us for such a long time!

Yuki Masuo M.D. @yuki-masuo.bsky.social · Apr 4

Thank you for coming all the way to Japan and showcasing your data! We look forward to inviting you again.

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Apr 4

by distinguished scientists @pgtimmune.bsky.social @virusesimmunity.bsky.social @soumya-boston.bsky.social @tsanglab.bsky.social and many others! Check out the new technologies and findings including unpublished ones! (2/2)

symposium.ashbi.kyoto-u.ac.jp/kyoto-immuno...

The Kyoto Immunology Symposium

symposium.ashbi.kyoto-u.ac.jp

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Yuki Masuo M.D. @yuki-masuo.bsky.social · Apr 4

Our Meeting Report is out in Nature Immunology 📣
The 22nd Takeda Science Foundation Symposium on Bioscience and The 1st Kyoto Immunology Symposium featured human immunology researches (1/2)

www.nature.com/articles/s41...

Human immunology soars in Japan - Nature Immunology

To address the increasing importance of studying immunology in humans, rather than a reliance on model systems, back-to-back symposia highlighting advances in human immunology were held in Osaka and K...

www.nature.com

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Reposted by Yuki Masuo M.D.

Nature @nature.com · Mar 26

Masaki Kashiwara is the first Japanese person to be awarded the most prestigious prize in mathematics

https://go.nature.com/4l4cy7f

Mathematician who reshaped theory of symmetry wins Abel Prize

Masaki Kashiwara is the first Japanese person to be awarded the most prestigious prize in mathematics.

go.nature.com

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