A detailed review of how iron, copper, zinc and other ions influence neuronal survival and pathology.
#IronMetabolism #MetalHomeostasis #Neurodegeneration #OxidativeStress
www.nature.com/articles/s41...

#WIMMReads: A new #review in Nature Reviews Immunology by Hal Drakesmith and Joe N Frost explores how #iron shapes immune responses in infection inflammation and cancer.
Read more 👇

#Immunology #Immunology #IronMetabolism #Infection
@rdm.ox.ac.uk @drakesmith-lab.bsky.social @medsci.ox.ac.uk

This review outlines how #ferroptosis—driven by #GPX4 regulation, #IronMetabolism, and #LipidPeroxidation—offers a strategy to reverse #DrugResistance in digestive system #cancers, highlighting emerging ferroptosis-inducing therapeutic approaches.

#OpenAccess: doi.org/10.1016/j.ge...

Watch the Tackling Iron Deficiency video on YouTube: youtu.be/frJ9iCjOYiM?...

#WIMMCommunity #Immunology #IronMetabolism #BCells #AntibodyResponse

Read the full story in @embojournal!
🔗 www.gimm.pt
#CellBiology #Immunology #Metabolism #Mitochondria #IronMetabolism #Homeostasis #OpenScience
(9/9)

This study shows that Jianpi Shengxue tablets are effective for #RenalAnemia in #CKD patients, significantly improving #IronMetabolism, relieving #Anemia symptoms, & enhancing nutritional status, promising advances in integrative #KidneyCare. #medsky

See: link.springer.com/article/10.1...

(1) New preprint from our lab!
HMOX1 controls a heme/ferritin switch that protects cells from ferroptosis.
Loss of HMOX1 stabilizes heme, boosts ferritin, and suppresses ferroptotic death.
👉 doi.org/10.1101/2025...
#ferroptosis #heme #ironmetabolism #preprint

Recent review on #Ferroptosis offers new strategies to reverse #DrugResistance in DigestiveCancers through #GPX4 pathways, #IronMetabolism, and #LipidPeroxidation, paving the way for targeted and combination therapies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Transferrin supplementation restores iron balance, prevents ferroptosis, and protects retinal cells, implying a novel therapeutic path for dry AMD.
#AMD #Retina #Ophthalmology #Ferroptosis #Transferrin #IronMetabolism #Neuroprotection #CellDeathDisease buff.ly/xt4Anvk

Patients with chronic inflammatory conditions often experience anemia of inflammation where iron is sequestered in storage sites like #macrophages, despite sufficient total body stores. SGLT2 inhibitors counter this process, leading to a beneficial shift in #ironmetabolism

Iron and the Gut Microbiome: A Delicate Balance with Clinical Implications
Iron is a key regulator of host–microbiome ecology and immune-metabolic balance.
Exciting work in Nature Microbiology.
Full article link in comments 👇
#Microbiome #IronMetabolism #Immunology

This review provides a detailed overview of #Ferroptosis characteristics and the mechanisms that allow #CancerStemCells to evade it, emphasizing its potential as an innovative cancer treatment strategy. #LipidPeroxidation #IronMetabolism #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

🧬 Recent research explores how gut microbiota influences hepcidin, the master iron regulator, shedding light on liver fibrosis development. 👉 buff.ly/spToNlU

#PathogDis #Microbiome #IronMetabolism #LiverHealth

It is not possible to understand #Alzheimer’s disease without understanding the involvement of #OralMicrobiome pathogens.

Not only is Alzheimer’s a disease, it is a microbial ecosystem.

#PGingivalis
#OralBacterialTranslocation
#OuterMembraneVesicles
#Lactoferrin
#Neuroinflammation
#IronMetabolism

Ouderen >85j krijgen minder vaak kanker dan 75-85-jarigen. Uit onderzoek blijkt dat veranderingen in hoe cellen omgaan met ijzer daar wellicht deels voor verantwoordelijk zijn: oude cellen ontzeggen zichzelf ijzer, waardoor ze trager groeien en moeilijker kanker kunnen worden - #ironmetabolism

Iron metabolism insufficiency in stem cells was not on my bingo card for mechanisms of aging that are chemoprotective... #Aging #LungCancer #IronMetabolism www.nature.com/articles/s41...