Scholar

Mikala Egeblad

Videos

Mikala Egeblad is a Bloomburg Distinguished Professor at Johns Hopkins School of Medicine. She is known for her research into… more

H-index: 52
Biology 45%
Medicine 41%
more

Reposted by: Mikala Egeblad

jaguirreghisolab.bsky.social
www.medpagetoday.com/hematologyon...
COVID Infection May Ignite Dormant Cancer in Survivors, Study Says
These patients should consider vaccination against respiratory viruses, according to researcher
www.medpagetoday.com
1 3

Reposted by: Mikala Egeblad

jaguirreghisolab.bsky.social
Delighted to see this story out and collaborate with amazing teams led by @jdegregori.bsky.social Mercedes Rincon & @roelvermeulen.bsky.social. Proud to see science propelled by our lab @cdi-einstein.bsky.social expanded to better understand cancer dormancy. Congrats! www.nature.com/articles/s41...
Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature
Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...
www.nature.com
5 11 36

Reposted by: Mikala Egeblad

maxkozlov.bsky.social
Hidden in the lungs of some breast cancer survivors are tumor cells that can remain dormant for decades — until they one day trigger a relapse.

Now, experiments show for the first time these rogue cells can be roused from their slumber by common respiratory illnesses such as COVID-19 or the flu.
‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu
Inflammation from the respiratory infections seems to be the culprit, study in mice finds.
www.nature.com
8 140 310

Reposted by: Mikala Egeblad

dukebrain.bsky.social
For early career researchers in our community - this is invaluable. Info here:
public.csr.nih.gov/ForReviewers...
7 5

Reposted by: Mikala Egeblad

hannahvmeyer.bsky.social
Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!
T cell receptor cross-reactivity prediction improved by a comprehensive mutational scan database
Banerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem...
www.cell.com
3 11 19

Reposted by: Mikala Egeblad

jaguirreghisolab.bsky.social
@megeblad.bsky.social once more revealing significant cancer biology - Congrats!
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
2 6

by Mikala Egeblad — Reposted by: Mikala Egeblad

megeblad.bsky.social
As a new postdoc in my lab (@cshlnews.bsky.social → @jhu.edu) @adrover.bsky.social (now @crick.ac.uk) saw NETs in tumors—I shrugged. But he looked closer in 3D: NETs block tumor vessels, driving necrosis, hypoxia, EMT & metastasis.
🔗 www.nature.com/articles/s41...
@jhu-bdps.bsky.social @nature.com
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
10 39

Reposted by: Mikala Egeblad

maxperutzlabs.ac.at
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details ➡️ tinyurl.com/3fbkp89c
1 44 37

Reposted by: Mikala Egeblad

elizsmckenna.bsky.social
It's my first #newPI roll call on BlueSky! Calling all new #cancer PIs who just started or who are about to start their labs! Please say hi and what you work on so I can follow you if I don't already! 😃
11 27

Reposted by: Mikala Egeblad

elizsmckenna.bsky.social
Great news! The AACR journals are now on BlueSky! Be sure to follow @aacrjournals.bsky.social!! #FollowFriday
12 39

Reposted by: Mikala Egeblad, Jennifer A. Richeson, David M. Amodio , and 1 more

goodaaron.bsky.social
I can confirm the PBS Passport is a very good deal for $5/month or $2.50/month if you do yearly.

Thousands of hours of top notch content. NOVA is great. The new Ken Burns doc on Leonardo da Vinci is excellent.

You can sign up at the link below!

www.pbs.org/passport/lea...
41 1.7K 2.5K

by Mikala Egeblad

megeblad.bsky.social
I hear you 😉 We found a type of clot-causing neutrophils in cancer. By blocking tumor vessels, they drive tumor necrosis, which in turn cause metastasis. Key message: Necrosis can be an active process and necrosis can cause metastasis. Free link to article here: www.nature.com/articles/s41...
1 2

Reposted by: Mikala Egeblad

cp-trendscancer.bsky.social
Platelets: tailoring metastasis treatment
Platelets: tailoring metastasis treatment
The dreadful liaison between platelets and tumor cells was discovered half a century ago. Since then, a plethora of studies have characterized the contribution of platelets to primary tumor development, survival of circulating tumor cells in the bloodstream, and metastatic seeding and outgrowth. Yet, although these provided a deep understanding of how platelets shape cancer progression, the field suffers from a lack of additional knowledge required to design efficient therapeutic strategies. Here, we aim to summarize recent discoveries that identify new ways in which platelets shape metastasis beyond their initial intravascular role. We further discuss platelet-borne molecular targets that could represent new avenues for therapeutically targeting platelets’ contribution to metastasis.
dlvr.it
1

Reposted by: Mikala Egeblad

clairem402.bsky.social
Check out some #CoolScienceImages (with music by Victor Leksell) from a @nature.com paper. In the study, @adrover.bsky.social, @megeblad.bsky.social, et al. found that neutrophil extracellular traps (NETs) drive tumor necrosis and metastasis: www.nature.com/articles/s41...
#FluorescenceFriday 🧪
3 9

Reposted by: Mikala Egeblad

ajbrenes.com
Exciting new work at @nature.com showing that Neutrophil Extracellular Traps in the vasculature can actively promote necrosis in cancer and that targeting NETs is can reduce necrosis and metastasis. Great work from @adrover.bsky.social @megeblad.bsky.social
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
2 11

Reposted by: Mikala Egeblad

adrover.bsky.social
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
3 25 61

Reposted by: Mikala Egeblad

helloeacr.bsky.social
[email protected] Postdoctoral Fellowships are awarded for a period of three years and support excellent postdoctoral researchers in laboratories throughout Europe. Is that you?

Apply by 20 August: eacr.org/eacr-fellows...
6 5

Reposted by: Mikala Egeblad

lozanzi.bsky.social
#WeekendRead! #BeyondNETosis! @caroleparentlab.bsky.social @sbarya.bsky.social &co show @natcellbio.nature.com that neutrophils can secrete nuclear-derived exosomes containing LTB4 & DNA which direct migration but at also favor inflammation resolution via neutrophil retrotransmigration!
Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation - Nature Cell Biology
Arya et al. report that migrating neutrophils resolve acute inflammation by releasing exosomes associated with nuclear DNA. This process is distinct from the release of neutrophil extracellular traps,...
go.nature.com
5 18

Reposted by: Mikala Egeblad

clausjorgensen.bsky.social
We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out
MI/25/33 - Postdoctoral Scientist Systems Oncology Group | Cancer Research UK Manchester Institute
Add brief description here
www.cruk.manchester.ac.uk
11 10

by Carl T. Bergstrom — Reposted by: Mikala Egeblad, Erin Baker, Andrew R. Morral , and 4 more

carlbergstrom.com
Very smart, high ROI initiative from the Spencer Foundation.

Providing bridge funding for canceled NSF grants:

1) directs funds to projects already screened by a top-noch review process.
2) avoids imposing proposal prep costs on researchers.
3) ameliorates the disruption from GOP sabotage.
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
www.spencer.org
6 340 780

Reposted by: Mikala Egeblad

mikelove.bsky.social
Up until June 2 (Monday) you can apply for scholarship to attend GBCC2025 at Cold Spring Harbor Laboratory. This is the Bioconductor / Galaxy joint conference at the end of June. You should submit a poster abstract to apply for scholarship. Scholarship details below.
Scholarship Tiers: • Tier 1 (registration + travel support up to $700) is limited and highly competitive. Only select this if you cannot attend without travel funding. A brief justification is required. • Tier 2 (registration only) is for applicants who can cover their own travel. You must confirm that travel funding is secured. • Tier 3 will cover the VIRTUAL conference registration only. What Registration Includes (Tiers 1 & 2) • Full access to sessions, workshops, and networking events • Daily meals (breakfast, lunch, dinner) • Welcome reception and banquet • On-campus housing • Free on-site parking
9 17

Reposted by: Mikala Egeblad

sitcancer.bsky.social
Only a few days left before The CheckPoints: Rockin’ for a Cure! Join us on Sunday, June 1 at Buddy Guy’s Legends in Chicago. A suggested donation of $30 at the door will support the #SITCForwardFund. Learn more: www.sitcancer.org/about/the-ch...
1 1

Reposted by: Mikala Egeblad

socdevbio.bsky.social
Michael Piacentino @mikepiacentino.bsky.social will be a speaker at #ICDB2025 and we couldn't be happier! Michael's work focuses on epidermal to mesenchimal transition in the highly migratory neural crest cells 🐤🧪
1 1 8

Reposted by: Mikala Egeblad, Adrienne Boire

danapeer.bsky.social
I am pleased to share our recent publication, fruit of a wonderful collaboration with truly amazing colleagues @adrienneboire.bsky.social and @meningojan.bsky.social, whose work was a tour de force demonstrating that immunology in the brain is a different beast -> www.nature.com/articles/s41...
Interferon-γ orchestrates leptomeningeal anti-tumour response - Nature
Independent of antigen presentation, migratory CCR7+ dendritic cells orchestrate the influx, proliferation and cytotoxic action of natural killer cells to control cancer cell growth in the leptomening...
www.nature.com
1 19 73

Reposted by: Mikala Egeblad

samreckpeterson.bsky.social
As the incoming Chair of Biochemistry and Biophysics at Weill Cornell Medicine, I am looking for a Director of Research. Exciting opportunity for a PhD scientist to shape the future of this new Department! Apply here: jobs.weill.cornell.edu/NY/job/New-Y...
Director of Research, Biochemistry & Biophysics
Director of Research, Biochemistry & Biophysics
jobs.weill.cornell.edu
19 30

Reposted by: Mikala Egeblad

johannajoyce.bsky.social
Thanks to all at #AACR25 for an inspiring and impactful annual meeting!

Filled with cutting-edge science 🧪- and the direct impact of those discoveries for patients with #cancer

Special thanks to co-chairs @mvhlab.bsky.social @lilliansiu.bsky.social

#CancerResearchSavesLives

@theaacr.bsky.social
Opening session of #AACR25 annual meeting - with all attendees raising signs in support of cancer research funding #CancerResearchSavesLives
4 42

by Mikala Egeblad

megeblad.bsky.social
Spring 2009 I opened my lab and accepted two @cshlnews.bsky.social rotation students now reunited at #AACR25: University of Hawaii Cancer Center clinician-scientist Elizabeth Nakasone, and Mount Sinai assistant professor and @theaacr.bsky.social NextGen Star @elvinwag.bsky.social - Made my day!
1 20

Reposted by: Mikala Egeblad

johannajoyce.bsky.social
We all know how much the microenvironment matters!

So grateful that the #TME field has so many fantastic - and supportive - women leaders 🙌

#AACR2025 🧪⚕️
#womeninscience
#payitforward

@theaacr.bsky.social
4 6 50

Reposted by: Mikala Egeblad

adrover.bsky.social
I had a wonderful time in the Tumor Microenvironment Working Group session! #AACR25 Thanks everyone for the warm welcome and lively discussion!
1 6

Reposted by: Mikala Egeblad

statnews.com
A clinical trial run by the National Cancer Institute seems to confirm that a single dose of the vaccine used to prevent infection with the human papilloma virus is just as effective as two

www.statnews.com/2025/04/28/h...
U.S. government researchers present 'phenomenal' new data on HPV vaccines
A new study seems to confirm that a single dose of the vaccine used to prevent HPV infection is just as effective as two — and, therefore, also helps to prevent cancer.
www.statnews.com
3 53 170

References

Fields & subjects

Updated 1m