Zaven Sargsyan
@sargsyanz.bsky.social
1.4K followers 180 following 570 posts
Internist at Baylor College of Medicine, Houston
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sargsyanz.bsky.social
Degradation of validity, elusiveness of truth everywhere
sargsyanz.bsky.social
Are a lot of google reviews fake / AI-generated now?

There's a company with 2.8 starts on 108 reviews on yelp

And 4.9 stars on 5,400 reviews on google - which all read very similar, and seem to concentrate heavily in the last several months.

My experience with the company was much more yelpy
sargsyanz.bsky.social
Second one has a flagellum
sargsyanz.bsky.social
Thanks.. I think some of it is driven by HF care accreditation/quality metrics imposed from on high (ACC or AHA)?
Reposted by Zaven Sargsyan
jamespirruccello.com
If non-dramas are allowed, Scrubs, to me, is the most evocative of what it was like to be a medical resident.
sargsyanz.bsky.social
The benefit of GDMT for HFrEF seems much greater / more important than of "GDMT" for HFpEF.

While the downsides--side effects, cost, pill burden, etc--are agnostic of benefit.

And yet I'm seeing a trend of "GDMT for HF" being increasingly conflated across the EF spectrum. Anyone else?
Reposted by Zaven Sargsyan
nejm.org
A 23-year-old man with autism spectrum disorder and chronic constipation presented to the emergency department with a 1-week history of abdominal pain on his left side, nausea, and vomiting. 1/2

#MedSky
sargsyanz.bsky.social
Interesting that they excluded uncomplicated cases.

Yes the complexity and risks of OPAT are greater in 6 rather than 2 weeks.

But much of it is front-loaded, e.g. PICC insertion, vanc levels/dosing, catheter thrombosis. Whereas cost of dalba linear with # of doses.
Reposted by Zaven Sargsyan
paulsaxmd.bsky.social
What the DOTS trial of Staph bacteremia tells us:
• Dalbavancin d1 and d8 vs daily IVs for WEEKS
• No left-sided IE/CNS/prosthetics
• Dalba not superior by DOOR endpoint, but similar clinical outcomes.
Big implications for inpt care. More here! #IDSky tinyurl.com/3hjzkt96
DOTS: Optimism Around a “Negative” Dalbavancin Trial
The DOTS randomized clinical trial of dalbavancin versus standard-of-care for Staph aureus bacteremia (SAB) just landed in JAMA, where it undoubtedly will be featured in numerous ID, hospitalist, and ...
tinyurl.com
Reposted by Zaven Sargsyan
davidjuurlink.bsky.social
Let's talk about using carbapenem antibiotics in patients with valproic acid (VPA) poisoning

/1🧵
sargsyanz.bsky.social
Any tips / anticipatory guidance about people on VPA at therapeutic doses who develop an ESBL infection?
Reposted by Zaven Sargsyan
davidjuurlink.bsky.social
PSA: When a naturopath recommends chelation “to remove the metal from your body,” that is exactly what you should not do.
Reposted by Zaven Sargsyan
emilyfri.bsky.social
Discussing this article for our QI didactic on Monday. So good.

journal.chestnet.org/action/showP...
sargsyanz.bsky.social
Also I love the thirsty evacuated container as the image of “decreased ascites formation” 😄
sargsyanz.bsky.social
Great read, thanks yall.

I’ve always been struck by how some folks have a lot of synthetic/hepatocellular dysfunction but little portal hypertension.. or vice versa.

Good argument that the relative contributions of each to MELD-Na might be actionable in this context..
Reposted by Zaven Sargsyan
juancarlosqvelez.bsky.social
Bold much-needed perspective by @sarahsanghavi.bsky.social et al about revisiting TIPS in the context of kidney disease, particularly in some cases of #HRS at #Kidney360 journals.lww.com/kidney360/ab...
journals.lww.com
sargsyanz.bsky.social
And their jugular veins are distended to the jaw even when they’re about to die of resultant septic and hypovolemic shock
Reposted by Zaven Sargsyan
drlongissimus.bsky.social
Bats get descending cholangitis
Reposted by Zaven Sargsyan
atheendar.bsky.social
I did a five month experiment where I signed off all social media. I felt smarter + less angry and distracted.
alexdecampi.bsky.social
A thought I keep having: what if I just log off all social media and subscribe to a few paper magazines and newspapers instead
sargsyanz.bsky.social
Congrats on 500, @thecurbsiders.bsky.social !

The episode was good, too. Would recommend it to folks wanting some updates on COPD, which there are many.

Even thymic stromal lymphopoietin made an appearance @paulnwilliams.bsky.social
thecurbsiders.bsky.social
🎉 We’re celebrating our 500th episode with a GIVEAWAY! 🎉

That’s 500 servings of knowledge food for your brain holes 🧠🍽️ — and we couldn’t have done it without YOU! Use the link below for more details! 👇🏼

www.instagram.com/p/DPejD3xEek...
Reposted by Zaven Sargsyan
empiricgame.bsky.social
Packing a lunch is not enough. You also need to bring it to work.
I am ready for the truth meme
sargsyanz.bsky.social
I've been thinking recently about how we heavily from ACEi -> ARB over the last 15 years, and that drug-induced chronic cough became much less common.

But now we've gone / we're going ARB -> ARNI for a lot of patients. Back on the bradykinin train. Drug-induced cough probs increasing again.