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Thomas Agoritsas

@thomasagoritsas.bsky.social

150 followers 120 following 22 posts

⚕️Physician & Prof🇨🇭🇬🇷🇫🇷 Geneva University Hospitals • McMasterU 🇨🇦 • Chair of MagicEvidence.org 🌍 • https://www.unige.ch/medecine/demed/recherche/thomas-agoritsas • Publications: https://scholar.google.com/citations?user=uoVzMm4AAAAJ&hl=en • Own 🦋 .. more

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Economics 20%

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Reposted by Thomas Agoritsas, Kamran Abbasi

The BMJ @bmj.com · 23h

"Moving beyond the uncomfortable apathy of medical neutrality is the duty of professionals and their organisations."

Where genocide, healthocide, and atrocities start, medical neutrality ends, says @kamranabbasi.bsky.social in this Editor's Choice
www.bmj.com/content/391/...

Image showing people clearing a bomb site in Gaza

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Reposted by Víctor M. Montori

Thomas Agoritsas @thomasagoritsas.bsky.social · 1d

A must-read. So much in there about what matters, and how to preserve it. 🙏

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Reposted by Thomas Agoritsas

Kamran Abbasi @kamranabbasi.bsky.social · 2d

“One factor is denial. Those responsible for genocide do not admit to their plans. Allies support their denials. Declassified documents show that US, French, and Belgian officials knew that genocide was occurring in Rwanda and avoided taking action” @bmj.com www.bmj.com/content/391/...

Testimony, advocacy, and the public health effect of genocide

Medical community must play its part in ending atrocities In 2000, JAMA published a commentary by Willis and Levy calling for action to ensure recognition of the public health impact of genocide.1 Th...

www.bmj.com

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Reposted by Víctor M. Montori, Thomas Agoritsas

EMRE KIZILKAYA @emrekizilkaya.bsky.social · 8d

A great discussion paper by Montori et al. for @harvard-carr-ryan.bsky.social.

They warn that surveillance capitalism is reshaping healthcare into a system focused on data rather than people, enabling Big Tech to commodify human experience and consolidate power:

www.hks.harvard.edu/centers/carr...

The Un-Mattering of People: The Present and Near-Future of Surveillance Capitalism and the Fate of Care in Healthcare

The encroachment of surveillance capitalism into healthcare takes place as healthcare becomes increasingly industrialized.

www.hks.harvard.edu

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Reposted by Thomas Agoritsas

Eric Topol @erictopol.bsky.social · 12d

More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose
nature.com/articles/s41...

Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis - International Journal of Obesity

International Journal of Obesity - Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis

nature.com

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Thomas Agoritsas @thomasagoritsas.bsky.social · 15d

“Loosing the information war?
- Get off social media
- Read good books & real journalism
- Find your friends
- And enjoy your life.”
samharris.substack.com/p/we-are-los...

We Are Losing the Information War with Ourselves

If the medium is the message, the message is mass psychosis.

samharris.substack.com

Reposted by Timothy Snyder, Richard E. Lenski, Michael Wagner , and 29 more Timothy Snyder, Richard E. Lenski, Michael Wagner, Koen Frenken, Stefan Reis, Thomas Agoritsas, Gavin L. Foster, Leigh Sparks, Amir Attaran, Jacob Montgomery, Donald Tomaskovic‐Devey, Cathy N. Davidson, Alison Phipps, Sanford F. Schram, Enzo Rossi, Nancy T. Ammerman, Peter Schöttler, Jonathan Hopkin, Laurent Pech, Leonhard Dobusch, W. Andy Knight, Rory O’Connell, Aurélien Mondon, Peter Stegmaier, Henry Jones, Henrik Skaug Sætra, Arlene Stein, Greg Linden, Pam Jarvis, Dan Immergluck, Annalee Newitz, Bill Hare

Robert Reich @rbreich.bsky.social · 15d

The richest man on earth owns X.

The second richest man on earth is about to be a major owner of TikTok.

The third richest man owns Facebook, Instagram, and WhatsApp.

The fourth richest man owns The Washington Post.

See the problem here?

1.9K 20K 58K

Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · 16d

5 problems in guideline development — solved with #MAGICapp 😎
✅ Simpler workflow
✅ Real-time collaboration
✅ Always up to date

🔗 Book a demo: forms.monday.com/forms/baaf06...
@thomasagoritsas.bsky.social @chrischampion.bsky.social

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Thomas Agoritsas @thomasagoritsas.bsky.social · 16d

There are no sides.

Reposted by Thomas Agoritsas

BMJ Medicine @bmjmedicine.bsky.social · 18d

How effective are de-implementation strategies to reduce low value care? Aleksi Raudasoja and colleagues conducted a systematic review and meta analysis to find out. 🧵

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Thomas Agoritsas @thomasagoritsas.bsky.social · 19d

Is that so? Sounds nonsensical and rude (particularly when added to a post celebrating a friendship). Good day to you.

Reposted by Thomas Agoritsas

Víctor M Montori MD @vmontori.bsky.social · 20d

Distinguishing the Difference Between Curing and Caring When Treating Patients | NEJM Catalyst catalyst.nejm.org/doi/full/10.... @patientrevolution.org

Distinguishing the Difference Between Curing and Caring When Treating Patients

Dr. Victor Montori, MD, MSc, Robert H. and Susan M. Rewoldt Professor of Medicine and leader of the Knowledge and Evaluation Research (KER) Unit at the Mayo Clinic and Co-Founder of The Patient Rev...

catalyst.nejm.org

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Thomas Agoritsas @thomasagoritsas.bsky.social · 21d

Strategic meetings beteeen MAGIC and WHO to support their clinical practice guidelines
@magicevidence.bsky.social @chrischampion.bsky.social

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · 21d

Operationalizing trustworthy #AI for #GRADE:
JUDGE turns tacit rating-down into 25 teachable prompts.
SMART-GRADE uses #LLMs + human-in-the-loop for traceable summaries.
Next: expand use cases + benchmarks with guideline panels. #GIN2025
@thomasagoritsas.bsky.social @guyattgh.bsky.social

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Thomas Agoritsas @thomasagoritsas.bsky.social · 21d

Privileged time and interactions with the one and only Gordon Guyatt at #GIN2025 in Geneva, with gratitude for the work and friendship 🙏
@magicevidence.bsky.social @guyattgh.bsky.social

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Thomas Agoritsas @thomasagoritsas.bsky.social · 21d

Wonderful presentation Prashanti! Thanks for all your beautiful work!

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Thomas Agoritsas @thomasagoritsas.bsky.social · 21d

Meeting long-known friends and colleagues Yuqing MadisonZhang and Pablo Alonso #GIN2025 conference in Geneva @magicevidence.bsky.social @gincomms.bsky.social

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · 22d

Coming up at #GIN2025 (Thursday 1h35pm room E): Prashanti Eachempati will present 2 big steps for #AI + GRADE 🚀
👉 JUDGE – 25 questions to justify rating down certainty
👉 SMART-GRADE – our LLM-powered tool to automate GRADE

Led by MAGIC with McMaster HEI . Come stop by!
@thomasagoritsas.bsky.social

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · 22d

@guyattgh.bsky.social on the core GRADE approach (BMJ) at #GIN2025
Simplifying GRADE is key to wider use—making it practical and accessible without compromising rigor.
At MAGIC, we see this balance as essential for evidence-based decisions that truly reach practice.
@thomasagoritsas.bsky.social

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · Sep 5

MAGIC at BE-SAFE in Warsaw 🇵🇱
Our colleagues @thomasagoritsas.bsky.social , Valerie & Sumanth joined the 4th #BESAFE Consortium Meeting, sharing updates and working on deprescribing #benzodiazepines guidelines.

besafe-horizon.eu/en/home

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Reposted by Thomas Agoritsas

Gordon H. Guyatt @guyattgh.bsky.social · Aug 31

Hanlon's Razor is a principle stating, "Never attribute to malice that which is adequately explained by incompetence". I’ve recently had an experience that put me in mind of these wise words – I suspected malevolence; explanation proved otherwise.

fs.blog/mental-model...

Hanlon's Razor: Not Everyone is Out to Get You

Hanlon’s razor is a mental safeguard against the temptation to label behavior as malicious when incompetence is the most common response

fs.blog

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Reposted by Thomas Agoritsas

Gordon H. Guyatt @guyattgh.bsky.social · Aug 7

Introducing #CHART - reporting guidelines for studies evaluating evidence summaries and health advice from #genAI models like #ChatGPT.

Authors may apply the CHART checklist ✅and methodological diagram 📈 when reporting their studies.

Published in @bmj.com: pubmed.ncbi.nlm.nih.gov/40750271/

Reporting guidelines for chatbot health advice studies: explanation and elaboration for the Chatbot Assessment Reporting Tool (CHART) - PubMed

Reporting guidelines for chatbot health advice studies: explanation and elaboration for the Chatbot Assessment Reporting Tool (CHART)

pubmed.ncbi.nlm.nih.gov

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Reposted by Gordon Guyatt, Thomas Agoritsas

The BMJ @bmj.com · Jul 30

"Evidence itself never gives us the answer what to do. It's evidence in the context of values and preferences."

Professor Gordon Guyatt talks to The BMJ about the challenges of evidence based medicine and introduces the Core GRADE system @guyattgh.bsky.social
www.youtube.com/watch?v=433J...

GRADE the trustworthiness of evidence | Prof. Gordon Guyatt

YouTube video by The BMJ

www.youtube.com

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Reposted by Víctor M. Montori, Thomas Agoritsas

Kamran Abbasi @kamranabbasi.bsky.social · Apr 15

Core GRADE was developed to provide the essentials of the GRADE approach in a single series of papers @bmj.com www.bmj.com/content/389/...

Why Core GRADE is needed: introduction to a new series in The BMJ

This article introduces a series of papers on new guidance for the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Core GRADE was produced in response to the need f...

www.bmj.com

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Thomas Agoritsas @thomasagoritsas.bsky.social · Jul 21

Evidence that most science is published from countries lacking in democracy and freedom of press
www.biorxiv.org/content/10.1...

Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · Jun 29

The BE-SAFE project is moving deprescription of benzodiazepines & sedative-hypnotics (BSHs) forward 💊✨

A SR/MA of 49 trials (just out in BMJ!) lays the foundation for trustworthy guidance on BSH deprescription
👉 www.bmj.com/content/389/...

@thomasagoritsas.bsky.social

Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis

Objective To review evidence from randomised trials assessing the effectiveness of strategies to deprescribe benzodiazepines and closely related sedative hypnotics (BSH). Design Systematic review and...

www.bmj.com

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Thomas Agoritsas @thomasagoritsas.bsky.social · Jun 27

Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST) - The Lancet www.thelancet.com/journals/lan...

For people with acute ischaemic stroke and atrial fibrillation, early DOAC initiation (within 4 days) reduced the risk of the composite outcome of recurrent ischaemic stroke, symptomatic intracerebral...

www.thelancet.com

Reposted by Gordon Guyatt, Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · Jun 23

Prof. @guyattgh.bsky.social, one of the founders of Evidence-Based Medicine #EBM, explains why #MAGICapp is a breakthrough for guideline development: multilayered, user-friendly, and built for trustworthy, living guidelines
Ping @thomasagoritsas.bsky.social @chrischampion.bsky.social

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · Jun 16

Recent changes at MAGIC😎:
#PerVandvik becomes Chief Scientist to deepen 🌏 partnerships & guide evidence innovation;
@chrischampion.bsky.social steps in as CEO to lead our next growth phase;
@thomasagoritsas.bsky.social now Board Chair, leading MAGIC with his sharp strategic thinking. +

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Reposted by Thomas Agoritsas

MAGIC Evidence Ecosystem Foundation @magicevidence.bsky.social · Jun 9

🚀 Big welcome to one of the founders of evidence-based medicine and our very own MAGIC Chief Methodologist—now on Bluesky! Hit “Follow” @guyattgh.bsky.social and join the conversation. 💥 #EBM #Bluesky
Ping @thomasagoritsas.bsky.social

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