Kevin Mitchell
@wiringthebrain.bsky.social
13K followers 2.1K following 2.3K posts
Neurogeneticist interested in the relations between genes, brains, and minds. Author of INNATE (2018) and FREE AGENTS (2023)
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wiringthebrain.bsky.social
You can define a set of behaviors that match what would be induced by a painful stimulus, without implying a subjective feeling of that state. But it seems pretty hard to deny - looking at an infant that just got hurt for the first time - that they're *in pain*...
Reposted by Kevin Mitchell
wilkinspsych.bsky.social
This is your field, not mine, but I would have thought that pain being innate was necessary. Pain thresholds can be altered, but unless I’m mistaken pain can’t be learned? I share your interest from a lower knowledge base. As with other senses, pain is linked to consciousness. Unconscious pain??????
Reposted by Kevin Mitchell
martinoh.bsky.social
Idiot with Internet access here, so dumb question: what does "*like that*" actually imply - is there a knowledge and understanding of what pain is that stage, or are there simpler underlying mechanisms that lead to reflex arcs, which can act as training inputs to further neural path development?
wiringthebrain.bsky.social
Oh, no. I'm not expressing sympathy for the poor little babies. I'm expressing amazement at how the subjective *feeling of pain* is somehow wired into their nervous systems!
Reposted by Kevin Mitchell
riannejar.bsky.social
Researchers confirm that PKMzeta, a so-called 'memory molecule,' working with another, KIBRA, is critical to making memories encoded in the strengths of synapses last a long time [via Scientific American] 🧪🧠

www.scientificamerican.com/article/brai...

#memory #neuroscience #neurons #synapses
Brain Scientists Finally Discover the Glue that Makes Memories Stick for a Lifetime
A long-running research endeavor reveals key chemical players that cement memories in place—and still more have yet to be discovered
www.scientificamerican.com
Reposted by Kevin Mitchell
Reposted by Kevin Mitchell
banditelli.org
May I offer you a borb in these trying times? 🪶
maybe a bushtit flying directly towards the camera , extremely puffed out
Reposted by Kevin Mitchell
oceanclub.bsky.social
The Iona Institute are a think tank that have stumbled on the grift that if your opinions are awful enough, the media will pay you to promote them rather than vice versa.
fancyvegaspro.bsky.social
All the talk about how many column inches would be dedicated to her, had overlooked that they could just give her a column of her own.

It's cool though. Now if I want the Iona Institute's view on things I can read Steen or Quinn in the Indo, or O'Brien in the Irish Times
Maria Steen: Significant spoilt vote in presidential election would embarrass the Government
After Jim Gavin’s exit, there is no good reason not to restart this lacklustre contest
Reposted by Kevin Mitchell
abeba.bsky.social
"Concerns over an AI bubble bursting have grown lately, with analysts recently finding that it’s 17 times the size of the dotcom-era bubble and four times bigger than the 2008 financial crisis." futurism.com/artificial-i...
Bank of England Warns of Impending AI Disaster
The Bank of England has sounded the alarm, warning of an intensifying risk of a "sudden correction" due to an AI spending frenzy.
futurism.com
Reposted by Kevin Mitchell
timothysnyder.bsky.social
History gives us plenty of examples of disease used as a weapon. There are fewer cases of governments deliberately using disease against their own citizens. We are living (or dying) through one right now.
www.nbcnews.com/health/healt...
Hundreds of U.S. students quarantined amid measles outbreaks
At least 270 unvaccinated kids are staying home from school as measles continues to spread nationwide. "Expect more," one expert said.
www.nbcnews.com
Reposted by Kevin Mitchell
gregpriest.bsky.social
The Hitchhiker’s Guide to the Galaxy was published OTD in 1979.

Douglas Adams: “Isn’t it enough to see that a garden is beautiful without having to believe that there are fairies at the bottom of it too?”

#litsci 🐡 #BookSky
Cover of first edition of the book
wiringthebrain.bsky.social
Not just qualia - innate qualia!
Reposted by Kevin Mitchell
edgibney.bsky.social
I see this as going back to Solms’ “affect” being the wellspring of consciousness. From the beginning, this pain and pleasure was selected for so it’s deep in the evolutionary history of life.

A wild speculation I’ve had is that silicon life hasn’t arisen because they feel pleasure at destruction.
Reposted by Kevin Mitchell
pessoabrain.bsky.social
𝗡𝗲𝘄 𝗹𝗮𝘄𝘀 𝗳𝗼𝗿 𝗲𝘃𝗼𝗹𝘃𝗶𝗻𝗴 𝘀𝘆𝘀𝘁𝗲𝗺𝘀?
Thought-provoking piece on properties of systems.
Including the Law of Increasing Functional Information, which applies to both biological and non-biological systems.
Physicists will probably not like this at all...
doi.org/10.1073/pnas...
#complexity
wiringthebrain.bsky.social
The first time an infant (or any creature) feels a painful stimulus... *it hurts*! They don't need to learn that it hurts - it just feels painful! Not just bad, but bad *like that*.

I find this very hard to deal with...
Reposted by Kevin Mitchell
oceanclub.bsky.social
People have forgotten how the algorithm on Twitter was changed so the most stupid, boring, venal, and fascist people - that is, the one who bought blue ticks - were the first you saw on the timeline and in replies.
alexvont.bsky.social
This is it. I didn’t find it at all difficult to leave Twitter in the end: it stopped being fun and became boring and depressing. Whenever I opened it I’d see things that were obnoxious or upsetting. It was a relief not to do that.
explaintrade.com
This is an exact encapsulation of why I moved to Bluesky.

No amount of handwringing in the Atlantic about how I owe some eternal Promethean suffering to the discourse is going to make me stay on a site I hate, that stopped doing anything for me professionally years ago.
Reposted by Kevin Mitchell
seamas.bsky.social
These very true words from Steve Hely have given me tremendous comfort over the years.
Writing a novel— actually picking the words and filling in paragraphs— is a tremendous pain in the ass. Now that TV’s so good and the Internet is an endless forest of distraction, it’s damn near impossible. That should be taken into account when ranking the all-time greats. Somebody like Charles Dickens, for example, who had nothing better to do except eat mutton and attend public hangings, should get very little credit.
Reposted by Kevin Mitchell
jennifernuzzo.bsky.social
This is a long RFK Jr talking point. He’s on script, I guess.
Reposted by Kevin Mitchell
gavinyamey.bsky.social
The lab leak conspiracy theorists running the US health agencies are getting kookier & kookier 🤦‍♂️

In fact, research shows that “the Lyme disease bacterium is ancient in North America, circulating silently in forests for at least 60,000 years” (medicine.yale.edu/news-article...)
Reposted by Kevin Mitchell
cwebbonline.com
It’s the Feds making Portland look like a war zone— not the protesters.

And honestly, these protesters are brilliant. They’re flipping the whole authoritarian cosplay on its ass!
Reposted by Kevin Mitchell
crushbort.bsky.social
is it not weird that every day there’s a new video of anonymous masked men having the time of their lives beating/shooting/disappearing people and the dem response from the top down is “republicans want to double your health insurance premiums”
Reposted by Kevin Mitchell
billkristolbulwark.bsky.social
Pope Leo quotes Hannah Arendt:

“The ideal subject of totalitarian rule is not the convinced Nazi or the convinced Communist, but people for whom the distinction between fact and fiction and the distinction between true and false no longer exist."

www.cbsnews.com/chicago/news...
Pope Leo calls for news agencies to stand as bulwark against "post-truths," lies and manipulation
Pope Leo XIV has encouraged international news agencies to stand firm as a bulwark against the "ancient art of lying" and manipulation.
www.cbsnews.com
Reposted by Kevin Mitchell
hishamzerriffi.bsky.social
“Your job is not to turn in completed assignments; it's to learn how to think.”

Ted Chiang‘s succinct summary of the issue with using AI in education.

I’m not a sports guy but the athlete metaphor he uses in this interview is pretty spot on.
The Incompatibilities Between Generative AI and Art: Q&A with Ted Chiang
The Incompatibilities Between Generative AI and Art: Q&A with Ted Chiang
cdh.princeton.edu