Lightnews — Scholar-powered news

Reposted by Yoann Santin

Matthieu Chavent @matthchavent.bsky.social · 1d

Our collaborative work with W Im lab is now published as V1 in @elife.bsky.social alongside with reviewers comments.

We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure!

doi.org/10.7554/eLif...

Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations

doi.org

1 3

Reposted by Yoann Santin

Ákos T Kovács @evolvedbiofilm.bsky.social · 1d

Extracellular ATP is an environmental cue in bacteria

@cp-cellreports.bsky.social

www.cell.com/cell-reports...

Extracellular ATP is an environmental cue in bacteria

Extracellular ATP acts as a signal regulating physiology and immunity in eukaryotes and is elevated during intestinal infection or damage. Tronnet et al. show that extracellular ATP reprograms the tra...

www.cell.com

11 26

Reposted by Yoann Santin

David Bikard @dbikard.bsky.social · 1d

Entretien pour Brut sur la vie Miroir, l'ingénierie génétique et l'éthique de ces recherches: www.brut.media/fr/videos/sc...

Manipulations génétiques, virus créés par l’IA, bactéries miroirs : quelles limites à la recherche scientifique ?

Elles pourraient aider à lutter contre les cancers… mais aussi détruire toute trace de vie sur Terre ! Ce sont les bactéries miroirs. En avez-vous déjà entendu parler ? Et la vie miroir, ça vous dit q...

www.brut.media

4 14

Reposted by Yoann Santin

Jovana Kaljevic ⬜️ @jovanakaljevic.bsky.social · 1d

Thrilled to see this work out. I enjoyed our collaboration @antoinehocher and loved working on this project. Congrats to the entire team! @tunglejic.bsky.social

Tung Le @tunglejic.bsky.social · 1d

new preprint from our group & Antoine Hocher: www.biorxiv.org/content/10.1...
A fantastic collaboration with Antoine, with Jovana Kaljevic' initiated the collaboration and drives the project.

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation

Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states through nucleotide binding and hydrolysis. These mechanis...

www.biorxiv.org

1 7 18

Reposted by Yoann Santin

Tung Le @tunglejic.bsky.social · 1d

new preprint from our group & Antoine Hocher: www.biorxiv.org/content/10.1...
A fantastic collaboration with Antoine, with Jovana Kaljevic' initiated the collaboration and drives the project.

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation

Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states through nucleotide binding and hydrolysis. These mechanis...

www.biorxiv.org

2 31 57

Reposted by Yoann Santin

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 1d

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation https://www.biorxiv.org/content/10.1101/2025.10.10.680097v1

4 7

Yoann Santin @ysantin.bsky.social · 2d

Après une semaine en compagnie de la #microbiologie francophone, #ETMM25 retour à Bruxelles ! Un grand merci à @ben-ezraty.bsky.social pour l'organisation et à tous les participants de mon atelier Proximity Labeling qui ont eu le courage de me supporter tard le soir ! À bientôt !

1 6

Reposted by Yoann Santin

STCmicrobeblog @stcmicrobeblog.bsky.social · 2d

𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 fans take note 👇

"𝘗. 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 senses EPS trails using type IV pili and adhesins during biofilm formation"

www.nature.com/articles/s41...
#MicroSky

figure from https://www.nature.com/articles/s41564-025-02087-4

7 18

Reposted by Yoann Santin

The EMBO Journal @embojournal.org · 3d

Type IV secretion systems: from structures to mechanisms
Kévin Macé and colleagues summarize recent structural insights into the assembly and function of bacterial type IV secretion systems
www.embopress.org/doi/full/10....

1 14 46

Reposted by Yoann Santin

The Francis Crick Institute @crick.ac.uk · 3d

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

110 130

Reposted by Yoann Santin

Zeynep Baharoglu @zeynepbaharoglu.bsky.social · 4d

Happy to share our new review in Royal Society Open Biology 🎉
tRNA-modifying enzymes in bacterial stress adaptation:
How tRNA mods rewire translation under oxidative + antibiotic stress (MoTTs, moonlighting, therapy angles).
Read: doi.org/10.1098/rsob...
#RNAsky #microsky #AMR #RNAmodifications

tRNA-modifying enzymes in bacterial stress adaptation | Open Biology

Transfer RNAs (tRNAs) and their modifications are central to bacterial translation and physiology, yet their roles in stress adaptation remain underexplored. While extensively studied in eukaryotes, a...

doi.org

17 29

Reposted by Yoann Santin

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 3d

The Legionella effector RidL promotes mitochondrial fragmentation through phosphorylation activation of the large GTPase Drp1 https://www.biorxiv.org/content/10.1101/2025.10.07.680855v1

1 2

Reposted by Yoann Santin

Cascales Lab @cascaleslab.bsky.social · 3d

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...

Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)

emploi.cnrs.fr

35 24

Reposted by Yoann Santin

Constantin Anoyatis @canopele.bsky.social · 4d

Proud of our new study out in @cp-cellreports.bsky.social!
Using E. coli lacking all 8 endopeptidases, we provide direct evidence that peptidoglycan expansion during elongation requires ED-mediated insertion of one glycan strand at a time. This can be performed by MepS, MepM, MepH and PBP7 #microsky

Role of endopeptidases in lateral cell wall expansion in Escherichia coli

Peptidoglycan, the major constituent of bacterial cell walls, is a giant macromolecule made of glycan strands cross-linked by short peptides, which pr…

www.sciencedirect.com

1 8 8

Reposted by Yoann Santin

Patricia Bernal @pbernalt6ss.bsky.social · 5d

Our paper, describing how the T6SSs of P. putida shape the tomato rhizosphere, is now in its final format in @isme-microbes.bsky.social ISME Communications. If you'd like to learn more, here is a thread (1/11) or read the Article doi.org/10.1093/isme....

2 18 51

Reposted by Yoann Santin

Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 3d

🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social [email protected] trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...

1 30 62

Reposted by Yoann Santin

Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 5d

Université Grenoble Alpes opens a full professorship in microbiology in 2026. The selected candidate will develop their research program on quantitative approaches in microbiology in the Laboratoire Interdisciplinaire de Physique. More info: liphy.univ-grenoble-alpes.fr/en/join-us/r...

Professorship (tenure) in 'Quantitative approaches in microbiology' (CNU Sections 64/65) | LIPhy - Université Grenoble Alpes

liphy.univ-grenoble-alpes.fr

8 5

Reposted by Yoann Santin

Basile Beaud Benyahia @babebe.bsky.social · 7d

Wonderful pair of papers by Augustinas Silale and Ben Berks on the diversity of BAM complexes.

Most diderm bacteria lack all BAM accessory previously identified in E. coli.

These two papers show a whole new set of accessory proteins in Bacteroidota.

How many more BAMs is there out there?
👁️👃🏼👁️

Augustinas Silale @augustsilale.bsky.social · 10d

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...

Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology

Structural and functional characterization of the β-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable β-barrel–surface lipoprotein complex assembly.

doi.org

4 10

Reposted by Yoann Santin

Tracy Palmer @proftracypalmer.bsky.social · 7d

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 7d

The Staphylococcus aureus LXG-domain toxins EsxX and SAR0287 do not promote virulence in a zebrafish larval infection model https://www.biorxiv.org/content/10.1101/2025.10.04.680436v1

19 32

Reposted by Yoann Santin

Vivek Mutalik @vivekmutalik.bsky.social · 7d

#microsky

Jelena Godrijan 🫧❾🌊🦋 @godi.bsky.social · 7d

⚠️New paper ➡️ isolating >600 freshwater microbes using dilution-to-extinction and low-nutrient, lake-mimicking media.

🤯Expands cultured diversity to ~70 % of detected genera and enables physiological studies of streamlined oligotrophs.

🔗 www.nature.com/articles/s41...
#protistsonsky

Bringing the uncultivated microbial majority of freshwater ecosystems into culture - Nature Communications

A large fraction of aquatic bacteria remains uncultured. Here, the authors cultivated 627 strains of abundant freshwater bacteria from 14 European lakes, thus generating a collection that includes many previously uncultured, oligotrophic bacteria that may serve as model organisms.

www.nature.com

1 9

Reposted by Yoann Santin

Phill Stansfeld @pstansfeld.bsky.social · 8d

Just in time for Becca’s thesis submission, their paper on MreB membrane interactions is published in @biophysj.bsky.social: www.cell.com/biophysj/ful... 🎉

3 10

Yoann Santin @ysantin.bsky.social · 8d

Great meeting !!

3

Reposted by Yoann Santin

Jan-Willem Veening @veeninglab.com · 8d

Finally out, such an awesome piece of work, very proud of this one: www.cell.com/cell-systems... #MicroSky

2 27 61

Yoann Santin @ysantin.bsky.social · 8d

Many thanks to the organization : @cascaleslab.bsky.social @romévoulhoux @maellepllt.bsky.social @thicoz.bsky.social @juliengiraud.bsky.social

3

Yoann Santin @ysantin.bsky.social · 8d

Very happy to have participated in the second edition of Secretion Day in Marseille. Great discussions with former colleagues! The Secretion community is awesome!

1 11