Alexandre Serafim
@2210alex.bsky.social
Pediatric Intensivist at Brasilia, Brazil
Reposted by Alexandre Serafim
One HPV vaccine dose delivers equivalent protection against HPV16 and HPV18 infection as two doses, with no safety issues.
by Kreimer AR, Porras C (...) Herrero R et 26 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2506765
by Kreimer AR, Porras C (...) Herrero R et 26 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2506765
December 12, 2025 at 8:34 PM
One HPV vaccine dose delivers equivalent protection against HPV16 and HPV18 infection as two doses, with no safety issues.
by Kreimer AR, Porras C (...) Herrero R et 26 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2506765
by Kreimer AR, Porras C (...) Herrero R et 26 al. in N Engl J Med #MedSky
👉 get more here
📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2506765
Reposted by Alexandre Serafim
We give babies vitamin k to prevent fatal hemorrhages. The movement against it is an obscene example of anti science drivel. It’s a vitamin!!
Between 2017 and 2024, the percentage of newborns not receiving intramuscular vitamin K for prophylaxis nearly doubled, with refusal rates highest outside hospital births and among certain racial and ethnic groups.
ja.ma/3XKTMaL
ja.ma/3XKTMaL
December 11, 2025 at 2:17 PM
We give babies vitamin k to prevent fatal hemorrhages. The movement against it is an obscene example of anti science drivel. It’s a vitamin!!
Chief Investigator, Evangelos Giamarellos-Bourboulis shares the findings from the #ImmunoSep trial and what it means for clinicians at #CCRdownunder
Livestream -> www.criticalcarereviews.com
@jama.com
Livestream -> www.criticalcarereviews.com
@jama.com
December 9, 2025 at 2:28 PM
Reposted by Alexandre Serafim
Co-Chief Investigators Brenda O'Neill and Danny McAuley share the results of the #iRehab trial after presenting at #CCRdownunder
Livestream -> www.criticalcarereviews.com
@jama.com
Livestream -> www.criticalcarereviews.com
@jama.com
December 9, 2025 at 7:17 AM
Co-Chief Investigators Brenda O'Neill and Danny McAuley share the results of the #iRehab trial after presenting at #CCRdownunder
Livestream -> www.criticalcarereviews.com
@jama.com
Livestream -> www.criticalcarereviews.com
@jama.com
Reposted by Alexandre Serafim
Chief Investigator Michael Reade provides an overview of the #CLIP-II trial at #CCRdownunder and what it means for clinicians.
@jama.com
@jama.com
December 9, 2025 at 7:34 AM
Chief Investigator Michael Reade provides an overview of the #CLIP-II trial at #CCRdownunder and what it means for clinicians.
@jama.com
@jama.com
Reposted by Alexandre Serafim
Chief Investigator Ary Serpa Neto shares an overview of the #ACTiVE trial after presenting the results at #CCRdownunder
@jama.com
@jama.com
December 9, 2025 at 7:41 AM
Chief Investigator Ary Serpa Neto shares an overview of the #ACTiVE trial after presenting the results at #CCRdownunder
@jama.com
@jama.com
Reposted by Alexandre Serafim
The Down Syndrome Medical Interest Group no longer has a Twitter/X account, but we have moved to Bluesky ❤️
Could any lovely #paedsky #paediatrics folks give it some love?
#paedsky #pediatrics
It's @dsmig.bsky.social
Also @rcpch.bsky.social - give it a follow 😁
Could any lovely #paedsky #paediatrics folks give it some love?
#paedsky #pediatrics
It's @dsmig.bsky.social
Also @rcpch.bsky.social - give it a follow 😁
December 7, 2025 at 9:23 PM
The Down Syndrome Medical Interest Group no longer has a Twitter/X account, but we have moved to Bluesky ❤️
Could any lovely #paedsky #paediatrics folks give it some love?
#paedsky #pediatrics
It's @dsmig.bsky.social
Also @rcpch.bsky.social - give it a follow 😁
Could any lovely #paedsky #paediatrics folks give it some love?
#paedsky #pediatrics
It's @dsmig.bsky.social
Also @rcpch.bsky.social - give it a follow 😁
Reposted by Alexandre Serafim
EXCLUSIVE: Epstein didn’t just prey on children. He helped bankroll and embed a worldview of race science, climate “culling” and eugenics inside Silicon Valley’s elite AI networks. Tonight we publish the final part of my
@bylinetimes.bsky.social investigation bylinetimes.com/2025/12/05/h...
@bylinetimes.bsky.social investigation bylinetimes.com/2025/12/05/h...
How Epstein Channelled Race Science and 'Climate Culling' Into Silicon Valley’s AI Elite
The Epstein files expose how racial hierarchy, genetic “optimisation” and even climate-driven population culling circulated inside Big Tech circles
bylinetimes.com
December 5, 2025 at 9:52 PM
Reposted by Alexandre Serafim
The decision by the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention to downgrade its recommendations to protect infants from hepatitis B is a dangerous move that will harm children.
Click here to read AAP's full statement: bit.ly/3Y9ZQJT
Click here to read AAP's full statement: bit.ly/3Y9ZQJT
December 5, 2025 at 4:15 PM
The decision by the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention to downgrade its recommendations to protect infants from hepatitis B is a dangerous move that will harm children.
Click here to read AAP's full statement: bit.ly/3Y9ZQJT
Click here to read AAP's full statement: bit.ly/3Y9ZQJT
Reposted by Alexandre Serafim
anaphylaxis to rocuronium can be treated with sugammadex. this is simple and really neat.
anaphylaxis to sugammadex is more complicated:
😁 if rxn to sugammadex *alone* --> giving roc will make things BETTER
😫 if rxn to [sugammdex-roc] *complex* --> giving roc will make things WORSE
#EMIMCC
anaphylaxis to sugammadex is more complicated:
😁 if rxn to sugammadex *alone* --> giving roc will make things BETTER
😫 if rxn to [sugammdex-roc] *complex* --> giving roc will make things WORSE
#EMIMCC
December 3, 2025 at 3:37 PM
anaphylaxis to rocuronium can be treated with sugammadex. this is simple and really neat.
anaphylaxis to sugammadex is more complicated:
😁 if rxn to sugammadex *alone* --> giving roc will make things BETTER
😫 if rxn to [sugammdex-roc] *complex* --> giving roc will make things WORSE
#EMIMCC
anaphylaxis to sugammadex is more complicated:
😁 if rxn to sugammadex *alone* --> giving roc will make things BETTER
😫 if rxn to [sugammdex-roc] *complex* --> giving roc will make things WORSE
#EMIMCC
Reposted by Alexandre Serafim
I'm late to this powerful, detailed article, but it's well worth a read. What we're doing to these people is an atrocity. www.newyorker.com/magazine/202...
Disappeared to a Foreign Prison
The Trump Administration is deporting people to countries they have no ties to, where many are being detained indefinitely or forcibly returned to the places they fled. Sarah Stillman reports.
www.newyorker.com
November 30, 2025 at 12:09 PM
I'm late to this powerful, detailed article, but it's well worth a read. What we're doing to these people is an atrocity. www.newyorker.com/magazine/202...
Reposted by Alexandre Serafim
Interesting cohort (adult) study in Canada on the association between respiratory drive and outcome. Limited by the observational design, but well done… and supporting the Lung and Diaphragm protective ventilation concept.
#PedsICU
www.sciencedirect.com/science/arti...
#PedsICU
www.sciencedirect.com/science/arti...
November 26, 2025 at 2:24 PM
Interesting cohort (adult) study in Canada on the association between respiratory drive and outcome. Limited by the observational design, but well done… and supporting the Lung and Diaphragm protective ventilation concept.
#PedsICU
www.sciencedirect.com/science/arti...
#PedsICU
www.sciencedirect.com/science/arti...
Reposted by Alexandre Serafim
Just an absolutely gutting essay by Tatiana Schlossberg, a writer, mother of two young children, and cousin of RFK Jr who is dying of leukemia.
www.newyorker.com/culture/the-...
www.newyorker.com/culture/the-...
November 22, 2025 at 4:09 PM
Just an absolutely gutting essay by Tatiana Schlossberg, a writer, mother of two young children, and cousin of RFK Jr who is dying of leukemia.
www.newyorker.com/culture/the-...
www.newyorker.com/culture/the-...
A powerful study by Dr Luiz Almeida (now in Saskatoon, formerly at Edmonton) on long term outcomes for kids after major heart surgery as infants.
www.cjcpc.ca/article/S2772-8129(25)00001-6/fulltext
#PedsICU
www.cjcpc.ca/article/S2772-8129(25)00001-6/fulltext
#PedsICU
November 22, 2025 at 11:01 AM
A powerful study by Dr Luiz Almeida (now in Saskatoon, formerly at Edmonton) on long term outcomes for kids after major heart surgery as infants.
www.cjcpc.ca/article/S2772-8129(25)00001-6/fulltext
#PedsICU
www.cjcpc.ca/article/S2772-8129(25)00001-6/fulltext
#PedsICU
Reposted by Alexandre Serafim
The AAP and more than 40 organizations are alarmed that the CDC is promoting the outdated, disproven idea that vaccines cause autism. We’re calling on the CDC to return to its long history of promoting evidence-based information to protect Americans’ health. Read the full statement: bit.ly/3XILwry
November 21, 2025 at 6:09 PM
The AAP and more than 40 organizations are alarmed that the CDC is promoting the outdated, disproven idea that vaccines cause autism. We’re calling on the CDC to return to its long history of promoting evidence-based information to protect Americans’ health. Read the full statement: bit.ly/3XILwry
Reposted by Alexandre Serafim
Pediatrician here.
Misinformation and disinformation don't become facts just because the CDC posted them.
Numerous studies have refuted any link between vaccines and autism.
Zero studies have shown any link between vaccines and autism.
Real science matters.
Misinformation and disinformation don't become facts just because the CDC posted them.
Numerous studies have refuted any link between vaccines and autism.
Zero studies have shown any link between vaccines and autism.
Real science matters.
November 21, 2025 at 1:43 AM
Pediatrician here.
Misinformation and disinformation don't become facts just because the CDC posted them.
Numerous studies have refuted any link between vaccines and autism.
Zero studies have shown any link between vaccines and autism.
Real science matters.
Misinformation and disinformation don't become facts just because the CDC posted them.
Numerous studies have refuted any link between vaccines and autism.
Zero studies have shown any link between vaccines and autism.
Real science matters.
Reposted by Alexandre Serafim
Single-center RCT finds benefit from sepsis resus that targets perfusion index (Pi)
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
November 18, 2025 at 3:15 PM
Single-center RCT finds benefit from sepsis resus that targets perfusion index (Pi)
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
Intervention group: fix macrohemodynamics, then target Pi >1.4
I think they're right
Pi is similar to cap refill, but continuously displayed number on monitor 😍
pubmed.ncbi.nlm.nih.gov/41033063/ #EMIMCC
Reposted by Alexandre Serafim
Last night I dreamed I was attending in the ICU. A trainee was presenting tons of data to me. I asked, “but what did the patient say when you asked them why they came to the hospital?”
In the dream, the trainee had to go ask them because they hadn’t yet.
I usually dream about real stuff, and
In the dream, the trainee had to go ask them because they hadn’t yet.
I usually dream about real stuff, and
Bedside clinical skills have been diminished by an overreliance on technology. A new Review Article presents educational strategies for reinvigorating the bedside encounter and shows how much can be learned from it. Learn more: nej.md/4nUirnP
#MedSky #MedEd
#MedSky #MedEd
November 17, 2025 at 3:33 PM
Last night I dreamed I was attending in the ICU. A trainee was presenting tons of data to me. I asked, “but what did the patient say when you asked them why they came to the hospital?”
In the dream, the trainee had to go ask them because they hadn’t yet.
I usually dream about real stuff, and
In the dream, the trainee had to go ask them because they hadn’t yet.
I usually dream about real stuff, and
Care of Infants and Children with Tracheostomies: An Official American Thoracic Society Clinical Practice Guideline
@chrisbakerbsky.bsky.social
@atscommunity.bsky.social #medsky
🔓 Open Access
🔗 tinyurl.com/4xczunce
@chrisbakerbsky.bsky.social
@atscommunity.bsky.social #medsky
🔓 Open Access
🔗 tinyurl.com/4xczunce
Care of Infants and Children with Tracheostomies: An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine
tinyurl.com
November 17, 2025 at 4:22 PM
Reposted by Alexandre Serafim
𝐀𝐂𝐓𝐢𝐕𝐄 𝐓𝐫𝐢𝐚𝐥 𝐑𝐞𝐬𝐮𝐥𝐭𝐬 𝐚𝐭 𝐂𝐂𝐑 𝐃𝐨𝐰𝐧 𝐔𝐧𝐝𝐞𝐫
➡️ Is automated closed-loop ventilation the future in ICU?
➡️ Expert analysis, big implications, live in Melbourne
➡️ Join us at CCR Down Under — don’t miss it!
criticalcarereviews.com/meetings/ccr...
➡️ Is automated closed-loop ventilation the future in ICU?
➡️ Expert analysis, big implications, live in Melbourne
➡️ Join us at CCR Down Under — don’t miss it!
criticalcarereviews.com/meetings/ccr...
November 16, 2025 at 9:41 PM
𝐀𝐂𝐓𝐢𝐕𝐄 𝐓𝐫𝐢𝐚𝐥 𝐑𝐞𝐬𝐮𝐥𝐭𝐬 𝐚𝐭 𝐂𝐂𝐑 𝐃𝐨𝐰𝐧 𝐔𝐧𝐝𝐞𝐫
➡️ Is automated closed-loop ventilation the future in ICU?
➡️ Expert analysis, big implications, live in Melbourne
➡️ Join us at CCR Down Under — don’t miss it!
criticalcarereviews.com/meetings/ccr...
➡️ Is automated closed-loop ventilation the future in ICU?
➡️ Expert analysis, big implications, live in Melbourne
➡️ Join us at CCR Down Under — don’t miss it!
criticalcarereviews.com/meetings/ccr...
Reposted by Alexandre Serafim
🧵 #HearthWarriors 🫂strike boycott blackout protest
****** defend the🫂 ... defund the 🐷 *******
#TruthWarriors ❕ bsky.app/profile/ezra...
****** defend the🫂 ... defund the 🐷 *******
#TruthWarriors ❕ bsky.app/profile/ezra...
Oh we're just getting started. www.rawstory.com/trump-ice-26...
Spotify hit with boycott calls after airing Trump's ICE ads: 'Don’t stream fascism'
Outrage over Spotify running advertisements for US Immigration and Customs Enforcement ramped up on Tuesday, with the progressive advocacy group Indivisible urging users to cancel their subscriptions ...
www.rawstory.com
November 15, 2025 at 10:23 PM
🧵 #HearthWarriors 🫂strike boycott blackout protest
****** defend the🫂 ... defund the 🐷 *******
#TruthWarriors ❕ bsky.app/profile/ezra...
****** defend the🫂 ... defund the 🐷 *******
#TruthWarriors ❕ bsky.app/profile/ezra...
Reposted by Alexandre Serafim
Today's Paper of the Day is:
Recent advances of precision immunotherapy in sepsis
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Recent advances of precision immunotherapy in sepsis
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
November 14, 2025 at 8:27 AM
Today's Paper of the Day is:
Recent advances of precision immunotherapy in sepsis
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Recent advances of precision immunotherapy in sepsis
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Reposted by Alexandre Serafim
November 14, 2025 at 9:25 AM
Reposted by Alexandre Serafim
👇🏼👇🏼👇🏼👇🏼
3/ The U.S. also spends far more on health care than any other wealthy nation, yet Americans live shorter, sicker lives. Infant & maternal mortality, chronic disease, and preventable deaths all rank near the worst. A key reason is that we underinvest in primary care and social supports.
November 13, 2025 at 1:24 AM
👇🏼👇🏼👇🏼👇🏼
Reposted by Alexandre Serafim
Is #PedsICU next?
💬 Editorial: The LIBERATE-D trial shows conservative dialysis—guided by A-E-I-O-U indications and asking "Why"—promotes earlier kidney recovery and fewer dialysis sessions in AKI.
#KidneyWK @asnkidney.bsky.social
ja.ma/4818ct1
#KidneyWK @asnkidney.bsky.social
ja.ma/4818ct1
November 7, 2025 at 5:28 PM
Is #PedsICU next?