Amelie Stein
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amelierocks.bsky.social
Amelie Stein
@amelierocks.bsky.social
1.8K followers 890 following 93 posts
Scientist. Mom. Coffee snob. Protein nerd.
Posts Replies Media Videos
amelierocks.bsky.social
So looking forward to this meeting!
muffley.bsky.social Lara Muffley @muffley.bsky.social · 8h
Also! We'd love your help in promoting this event in the #Australia #Australasia region! Topics and programming will be of interest to the #FunctionalGenomics #Genomics #Clinical #Research #Community ℹ️https://www.mss2026.org
November 25, 2025 at 7:29 PM
Reposted by Amelie Stein
yurabykov.bsky.social
Junior professor position at the University of Kaiserslautern! Our Department of Biology is seeking a colleague working with microalgae. This is a wonderful place to do wonderful science with great people! Please, repost :)
Further details:
jobs.rptu.de/jobposting/1...
November 20, 2025 at 3:28 PM
amelierocks.bsky.social
T’is the season
When I scrape ice
Off my saddle
Bike saddle covered in thousands of frozen droplets. Green grass and brown leaves in the background.
November 20, 2025 at 1:13 PM
Reposted by Amelie Stein
realscientists.de
🧵 Thread👇
Heute Nachmittag im Fokus:

Wissenschaftliche Karrierewege

An der Uni wird oft nur das Karriereziel Professur diskutiert, aber der Weg dahin ist schwer, wenig planbar und die anderen Berufsoptionen sehr vielfältig (und zumeist sogar besser).
spongebob is writing on a piece of paper with a pen .
ALT: spongebob is writing on a piece of paper with a pen .
media.tenor.com
November 19, 2025 at 3:21 PM
Reposted by Amelie Stein
jeymccreight.bsky.social
I lament all the research and writing I never got to do because I was too busy fighting sex pests and institutionalized misogyny
needhibhalla.bsky.social Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 9d
Sexual harassment is a productivity tax on women in STEM
chanda.blacksky.app Chanda Prescod-Weinstein 🌌 @chanda.blacksky.app · 9d
Imagine the things we could do with our time if we didn’t have to do this bsky.app/profile/chan...
November 16, 2025 at 7:39 PM
Reposted by Amelie Stein
odedrechavi.bsky.social
Adding citations of people who might review the paper
November 14, 2025 at 10:06 AM
Reposted by Amelie Stein
peiferlabunc.bsky.social
One of my science heroes, Joan Brugge, talks about how science funding cuts are slowing their work on breast cancer prevention--share this widely
www.facebook.com/60minutes/vi...
439K views · 15K reactions | Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was ...
Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was just like a gut punch. My...
www.facebook.com
November 10, 2025 at 11:12 AM
amelierocks.bsky.social
Fall is beautiful, even on gray days 🍂 🍁
Path by a creek strewn with leaves Ducks on the creek
November 8, 2025 at 12:08 PM
Reposted by Amelie Stein
meadekrosby.bsky.social
Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).
Rosalind Franklin and the damage of gender harassment
Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t
www.science.org
November 7, 2025 at 7:58 PM
amelierocks.bsky.social
My 11yo is more active in her Teams chats than I am in mine.
November 7, 2025 at 1:44 PM
amelierocks.bsky.social
Danish design cup
Royal Copenhagen cup filled with Lego
October 28, 2025 at 12:03 PM
Reposted by Amelie Stein
pedrobeltrao.bsky.social
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
GitHub - aqlaboratory/openfold-3: OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3
OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3 - aqlaboratory/openfold-3
github.com
October 28, 2025 at 9:30 AM
Reposted by Amelie Stein
peiferlabunc.bsky.social
The UNC Department of Biology is seeking a Director of Biology Teaching Labs, a key leadership role overseeing our undergraduate laboratory program. 1/n
Learn more and apply here: unc.peopleadmin.com/postings/308...
Director of Biology Teaching Labs
The Director of Biology Teaching Labs provides leadership and direction in the management of the Biology Department's undergraduate laboratories and will be responsible for the undergraduate laborator...
unc.peopleadmin.com
October 27, 2025 at 2:12 PM
Reposted by Amelie Stein
markhamillofficial.bsky.social
I have a very bad feeling about this...
October 27, 2025 at 4:51 PM
Reposted by Amelie Stein
laurahowes.bsky.social
Alternatively, lads, might be worth thinking about supporting the German car industry to remain viable in the future rather than locking them into a dying business model.
But sure, you go off...
katjadiehl.bsky.social Katja Diehl @katjadiehl.bsky.social · Oct 25
Ich schäme mich so.

"In einem Beschlusspapier der Ministerpräsidentenkonferenz in Mainz heißt es, das starre Verbot der Verbrennertechnologie ab dem Jahr 2035 gefährde die Wettbewerbsfähigkeit des Automobilstandortes Deutschland."

www.deutschlandfunk.de/ministerprae...
Mainz - Ministerpräsidenten gegen Verbrenner-Aus 2035 - Söder: Klimaziele in Europa gefährden Wohlstand
Die Bundesländer fordern eine Neuregelung des Verkaufsverbots in der EU für Autos mit Verbrennermotoren.
www.deutschlandfunk.de
October 25, 2025 at 8:52 AM
amelierocks.bsky.social
Airplane sunrise is the reward for early departures.
Looking forward to European RosettaCon 2025!
Blazing colourful sunrise seen through an airplane window
October 20, 2025 at 6:38 AM
amelierocks.bsky.social
Kiel
Kiel Marina, sail boats Planters along the marina Threemaster behind a large tree
October 13, 2025 at 2:18 PM
Reposted by Amelie Stein
ijayas.bsky.social
Ah, a classic moment of @nature.com recognizing the scientific contributions of both genders: man and machine.
profannawatts.bsky.social Prof Anna Watts @profannawatts.bsky.social · Oct 9
Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.
Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."
October 9, 2025 at 7:40 PM
Reposted by Amelie Stein
madic.bsky.social
You can get MSAs directly from AlphaFold DB now (alphafold.ebi.ac.uk). I also missed the FoldSeek implementation, which lets you search for structurally similar proteins direktly.

This saves some clicking around. Neat!
October 7, 2025 at 2:54 PM
Reposted by Amelie Stein
evoneuro.bsky.social
As I tell my students, if you arrived at a simple answer in biology you have done one of two things: arrived at the wrong answer or asked the wrong question
clauswilke.com Claus Wilke @clauswilke.com · Oct 7
Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon.
blog.genesmindsmachines.com/p/we-still-c...
We still can’t predict much of anything in biology
Biology is hard. Yes, even for AI.
blog.genesmindsmachines.com
October 9, 2025 at 2:38 PM
amelierocks.bsky.social
Kindergarten teacher asks what I teach (biological sequence analyses), I try to explain.
She turns to the 3yo and asks „What do you want to be when you grow up?“

Prompt and confident answer: „A butterfly 🦋!“
October 9, 2025 at 4:19 PM
Reposted by Amelie Stein
lindorfflarsen.bsky.social
The proteasome-substrate-shuttle protein UBQLN2 contains—like other quality control system proteins—a long region devoid of lysine (a lysine desert)

Martin Grønbæk-Thygesen (from @rhp-lab.bsky.social) et al show that introducing K here causes ubiquitylation and degradation

doi.org/10.1101/2025...
Fig. 1 – UBQLN2 is a conserved lysine-depleted protein. (A) Sequence comparison of UBQLN2 orthologs in the indicated species. Intrinsically disordered regions in human UBQLN2 based on MobiDB are shown as a blue bar. The domain organization based on the SMART database is marked. Lysine residues are marked as black squares. (B) ESM-2 predictions of all possible single amino acid substitutions of human UBQLN2 presented as a heat map. The wild-type residues are marked in blue. ESM-2 scores close to zero (light yellow colors) indicate that the amino acid substitution is compatible with the ESM-2 language model, whereas negative scores (dark orange colors) indicate that the variant is incompatible with the ESM-2 model. The domain organization (based on SMART) is aligned above the map. Note that substitutions to lysine or cysteine in general appear detrimental, in particular downstream of the UBL domain. (C) The AlphaFold2 predicted structured of human UBQLN2 (AF-Q9UHD9-F1) (left panel). The UBL domain is colored blue, and the UBA domain is colored orange and the STI1 regions green. Zoom in on the UBL domain (right panel) with the lysine residues highlighted as stick representations and colored based on the relative accessible surface area (rASA, dark red exposed; grey, buried).
October 7, 2025 at 9:20 PM
Reposted by Amelie Stein
lizbwood.bsky.social
For every Nobel that goes to a criminally under-recognized woman scientist (Brunkow, Karikó), or fails to go (Candy Lee), a week of mourning and reform for an academic system wherein you can do Nobel-prize-worthy-work and still end up without a conceivable path to being a professor.
nature.com Nature @nature.com · Oct 6
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize
A photo of a Nobel medal
October 6, 2025 at 10:13 AM
amelierocks.bsky.social
Fun & action the local science museum

#experimentarium
Small child standing by a goods transport model (essentially a very large rolling ball sculpture), next to a sign labelled København, putting orange balls onto the rails.
October 5, 2025 at 1:27 PM
Reposted by Amelie Stein
irinabezsonova.bsky.social
This October I’m drawing one molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social

Day 2/31
Prompt WEAVE

N-terminal domain of a Fibrion - a building block of silk fiber produced by silkworms.

Pdb: 3UA0

Next prompt is CROWN and I would love your suggestions!
October 3, 2025 at 3:29 AM