Alex Tatara, MD PhD
@amtatara.bsky.social
1.9K followers 180 following 36 posts
Physician scientist engaged in biomaterials, immunoengineering, and device-related infection. Assistant prof at UTSW.
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Reposted by Alex Tatara, MD PhD
cidjournal.bsky.social
Patient-reported perceptions, experiences and preferences around intravenous and oral antibiotics for the treatment of Staphylococcus aureus bacteremia: a descriptive qualitative study.

✅ Just Accepted
#IDSky
🔗 https://bit.ly/3Iil2JB
Reposted by Alex Tatara, MD PhD
josephmarcusid.medsky.social
My team’s new article is out!

For male basic trainees who had ICD-10 code for UTI or dysuria:

~50% had a sexual history documented
~70% had a gc/ct test ordered,
-Ultimate diagnosis of gc/ct >>> uti
-Few had any STI testing in 3 years following dysuria

#IDSky

academic.oup.com/milmed/advan...
Testing for Sexually Transmitted Infections in Symptomatic Male Military Trainees
AbstractIntroduction. A high burden of sexually transmitted infections (STIs) exists among trainees entering United States Air Force Basic Military Trainin
academic.oup.com
amtatara.bsky.social
We had a wonderful time looking at biomaterials through the lens of ID! Thanks for the RT
amtatara.bsky.social
Many thanks to Jay Vyas for writing such an insightful commentary to our article in Clinical Infectious Diseases- pubmed.ncbi.nlm.nih.gov/40470539/.
Reposted by Alex Tatara, MD PhD
utswinfdis.bsky.social
Congrats to our fantastic ID fellow (Dr. Hannah Blanchard) and ID Faculty (Dr. Hayden Andrews, Dr. Netanya Utay) on their timely publication in @cidjournal.bsky.social on Measles immunity at our HIV clinic!! 👏
academic.oup.com/cid/advance-...

@bradcutrellmd.bsky.social @netanyautay.bsky.social
amtatara.bsky.social
The disappointment after trying to buy dinosaur Elvis taught me a lot of life lessons
amtatara.bsky.social
I remember playing this for hours at our library!! Can’t wait to watch…
amtatara.bsky.social
So neat! Do we know why?
Reposted by Alex Tatara, MD PhD
erinmccreary.bsky.social
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025

fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
Reposted by Alex Tatara, MD PhD
steventong.bsky.social
We’ve got something in review that addresses this question (as much as observational data can). Basically we think all ASPs the same compared to cefazolin
Reposted by Alex Tatara, MD PhD
quinnfeld.bsky.social
Dr Steven Tong presents data on Penicillin vs (Flu)Cloxacillin for penicillin sensitive S.aureus.

1. Penicillin is non-inferior.
2. Rate of AKI roughly half in Penicillin group.
3. More pts in Penicillin group changed Rx - why?
#ESCMIDGlobal
Reposted by Alex Tatara, MD PhD
angelahuttner.bsky.social
#ESCMIDGlobal starts soon 🤓
There's a new latebreaker session created to give 2-3 'big' trials their due: 'Trial Run', Sat 16:15
2 #SNAP trials + CloCeBa trial will be discussed in real detail Moderators @vancefowler.bsky.social +Julia Bielicki. @gurujosh.bsky.social @steventong.bsky.social #IDSky
Reposted by Alex Tatara, MD PhD
jama.com
JAMA @jama.com · Apr 7
Staphylococcus aureus bacteremia has a case fatality rate of 15% to 30% and causes 300 000 deaths per year worldwide. This Review discusses management of S aureus bacteremia. https://ja.ma/3RF8b50
Staphylococcus aureus Bacteremia: A Review
This narrative review summarizes current evidence on the epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment of Staphylococcus aureus bacteremia.
ja.ma
amtatara.bsky.social
Come join us! Hiring a postdoc to work on immunotherapy to prevent and treat orthopaedic infection. I'll be at SFB2015 in Chicago if you want to chat about life in Dallas at our fabulous program. lnkd.in/evpKR5KE
lnkd.in/e7K2PMgh
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
Reposted by Alex Tatara, MD PhD
id-journal.bsky.social
🔍 Study on 47 kids with musculoskeletal infections vs. 48 Lyme & 49 inflammatory arthritis. A 3-cytokine panel (IL-6, IL-17A, CSF-1) had AUC 0.90, outperforming 5 common biomarkers (P < .05).##idsky
Utility of Cytokine Biomarkers for the Diagnosis of Pediatric Pyogenic Musculoskeletal Infections
Pyogenic musculoskeletal infections, such as septic arthritis and osteomyelitis, require prompt recognition and treatment but can be challenging to distinguish from Lyme or inflammatory arthritis. Our goal was to identify cytokine biomarkers of musculoskeletal infections.MethodsUsing 2 multicenter prospective cohorts of children undergoing emergency department evaluation for musculoskeletal infection, we selected children ≤21 years of age with a musculoskeletal infection (cases) matched by age and sex to children with Lyme and inflammatory arthritis (controls). We performed a 45-cytokine/chemokine panel using the Olink proximity extension assay platform and used receiver operator curve analysis to evaluate the discriminative ability of each cytokine. Using forward stepwise logistic regression, we derived a 3-cytokine panel and compared the accuracy with 5 commonly available plasma biomarkers.ResultsWe included 47 children with musculoskeletal infection, 48 with Lyme arthritis, and 49 with inflammatory arthritis. Interleukin-6 had the highest accuracy for musculoskeletal infection (area under the curve [AUC], 0.84; 95% CI, 0.77–0.91). A 3-cytokine biosignature panel (interleukin-6, interleukin-17A, and colony stimulating factor–1) had the highest overall accuracy (AUC, 0.90; 95% CI, 0.84–0.96) and performed better than 5 common plasma biomarkers (white blood cell count, absolute neutrophil count, C-reactive protein, erythrocyte sedimentation rate, and procalcitonin; P < .05 for all comparisons).ConclusionsPlasma cytokines can distinguish musculoskeletal infections from Lyme or inflammatory arthritis and may assist initial decision-making for children undergoing evaluation for musculoskeletal infection.
academic.oup.com
Reposted by Alex Tatara, MD PhD
gurujosh.bsky.social
Excited to announce that we randomised our first patient in the @roadmaptrial.bsky.social today! First of thousands, answering important questions in prosthetic joint infection. See roadmaptrial.com for more deets. #IDSky #PJI #ROADMAP
Welcome to the ROADMAP Trial – Examining treatments for PJI
Explore our website to learn more about our trial, team, and how you can get involved in shaping the future of PJI treatment.
roadmaptrial.com
Reposted by Alex Tatara, MD PhD
amtatara.bsky.social
“I’ll give you something to diarrhea about”
Reposted by Alex Tatara, MD PhD
idsainfo.bsky.social
In OFID, Seongman Bae and colleagues elucidate risk factors associated with 30-day infection-attributable mortality in a large cohort of patients with Staphylococcus aureus bacteremia (SAB).
Risk Factors for Infection-Attributable Mortality in Patients With Staphylococcus aureus Bacteremia: A Competing Risk Analysis
buff.ly
amtatara.bsky.social
Agreed! Just thought may be less inconvenient than micafungin infusions if that was an option you were considering