Jeff Lewis
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lewislab.bsky.social
Jeff Lewis
@lewislab.bsky.social
Interested in understanding how organisms sense and respond to stressful environments, and why some individuals are more sensitive or more resilient. he/his
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Very excited to announce that our department is now accepting applications for a tenure track faculty position in Cell Biology: uasys.wd5.myworkdayjobs.com/en-US/UASYS/...

Come join our wonderful department!
Assistant Professor Cell Biology
Current University of Arkansas System employees, including student employees and graduate assistants, need to log in to Workday via MyApps.Microsoft.com, then access Find Jobs from the Workday search ...
uasys.wd5.myworkdayjobs.com
💯 Instead of remaining calm, ICE approached protesters, and then violently pushed them to the ground, pepper sprayed, and started beating. All of that should not be happening, whether or not it culminates in shooting someone in the back.
Important context, this is the victim’s behavior BEFORE being tackled

He’s not threatening, he’s not brandishing, he’s filming
Video before it happens is showing this guy they shot in the head in Minneapolis was just standing there videoing them before and they got out to push him back and then murder him.
January 25, 2026 at 12:40 PM
Reposted by Jeff Lewis
Important context, this is the victim’s behavior BEFORE being tackled

He’s not threatening, he’s not brandishing, he’s filming
Video before it happens is showing this guy they shot in the head in Minneapolis was just standing there videoing them before and they got out to push him back and then murder him.
January 24, 2026 at 6:17 PM
Reposted by Jeff Lewis
Now applications are getting kicked to SEPs due to a "surge in applications". Everything is fine.
January 23, 2026 at 8:30 PM
Reposted by Jeff Lewis
New paper with @smishra677.bsky.social!

How many different trees can be generated by just one duplication event? It turns out A WHOLE LOT, if you consider the coalescent process.

1/

www.biorxiv.org/content/10.6...
www.biorxiv.org
January 23, 2026 at 11:10 AM
Reposted by Jeff Lewis
Sent an email last night to the members of my department encouraging them to contact our Congressional representatives with a simple ask: use 2024 multi year funding levels, NOT 2025 multi year funding levels, in the 2026 NIH funding bill
Here’s the deal with the FY26 NIH funding bill:

One line in the 1000+ pg bill = significantly less science.

The increase to ~40% of grants moving to MYF is estimated to result in a 35% decrease in the NUMBER of NIH grants funded annually—moving the paylines from 10% to around 4%.

THIS IS BAD.
January 21, 2026 at 4:52 PM
Reposted by Jeff Lewis
Just called my Senators to push for a minibus amendment to block multiyear funding (MYF), a gimmick cooked up by OMB to underfund cancer research and other programs that are meritorious and critical to our nation’s health, economy, and global leadership in science and medicine
January 21, 2026 at 8:06 PM
Reposted by Jeff Lewis
"It’s this snowball, domino effect that’s going to take decades to build back from, if we’re even given the opportunity to...This is not about like, ‘Oh, if we just get Democrats in power in the next couple of years, like, everything will just be fine’ … We’re looking at decades of damage”
Here is the article, which IMO shows the breadth of damage quite well. So my team doesn't get too freaked out, I'm misquoted slightly in terms of how long my lab has until it would have to close--we'll be ok this year* but I need a good score in ~6 months or we're cooked. thehill.com/homenews/edu...
thehill.com
January 21, 2026 at 11:29 PM
Reposted by Jeff Lewis
Here is the article, which IMO shows the breadth of damage quite well. So my team doesn't get too freaked out, I'm misquoted slightly in terms of how long my lab has until it would have to close--we'll be ok this year* but I need a good score in ~6 months or we're cooked. thehill.com/homenews/edu...
thehill.com
January 21, 2026 at 5:38 PM
Reposted by Jeff Lewis
the original language in the Senate appropriations bill kept the MYF policy to 2024 levels

ask your congressional representatives for the current language in the funding bill to be replaced with this language: keep MYF at 2024 levels, NOT 2025 levels 🧪
January 20, 2026 at 11:41 PM
Reposted by Jeff Lewis
The NIH's MYF policy in 2025 resulted in 4000 fewer grants and fellowships that touched every area of biology and medicine; continuing it in 2026 would be disastrous for science, technology and health in the United States 🧪
www.nytimes.com/interactive/...
January 20, 2026 at 11:39 PM
Reposted by Jeff Lewis
So what can we do?

Start now and demand no votes for this bill unless the MYF provision is returned — to ban MYF at NIH this year, to set it to zero. We can still do this.

But if scientists stick their heads in the sand and deny reality, we cannot even begin to fight. Realistic optimism.
January 20, 2026 at 11:29 PM
Reposted by Jeff Lewis
Just spoke to The Hill about how the dismantling of the NIH is impacting science in America. We still face a cliff of unfathomable heights, w easily 1000+ labs poised to close in the next year due to funding ending. A generation of young scientists lost because there is nowhere for them to train.
January 20, 2026 at 4:03 PM
Reposted by Jeff Lewis
The conference (agreement between House and Senate) appropriations bill that includes HHS and NIH was released this morning.

www.appropriations.senate.gov/news/majorit...

1/5
Committee Releases Conferenced Defense, Homeland Security, Labor, Health and Human Services, Education, and Related Agencies, and Transportation, Housing and Urban Development, and Related Agencies Bi...
United States Senate Committee on Appropriations
www.appropriations.senate.gov
January 20, 2026 at 3:55 PM
Reposted by Jeff Lewis
IMO, continuing to do science, to support science and to do so in pursuit of truth & support of human rights is a form of pushback. It’s not to say “put your head down, do good science & things will be fine” but to say as long as you can, it is resistance.
January 17, 2026 at 10:00 PM
Reposted by Jeff Lewis
Visit days where potential grad student admits are brought to campus are starting soon. I have some info on what to expect at applyingtoeeb.info

For those making schedules for such events, I have an #rstats package for that; sample fn: bomeara.github.io/scheduleR/re...

🧪 #AcademicSky
January 17, 2026 at 2:55 PM
Reposted by Jeff Lewis
I’ve heard this as well. I’ve also heard that the veto is (I quote) a “bullsh*t” threat.

Regardless, I hope Congress is smart enough to let the White House take the political hit of vetoing an NIH funding bill (and along with it the DoD funding bill) rather than removing that language.
The appropriations bill that includes NIH is being finalized.

The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.

The House version does not and OMB has issued a veto threat if the House includes such language.

1/3
a close up of a brown surface with a few spots
ALT: a close up of a brown surface with a few spots
media.tenor.com
January 14, 2026 at 5:27 PM
Reposted by Jeff Lewis
We made a new lager beer! "Indomitus" for wild and untamed. Brewed with a wild yeast strain from Patagonia! This is the result of a super fun collaboration (and lots of hard work) with Francisco Cubillos in Chile (@fcocubillosr.bsky.social) and Andrés Furukawa at the Nils Oscar Brewery in Sweden.
January 15, 2026 at 1:02 PM
Gotta put pressure here on the House to limit MYF. Vetoing the budget over MFY is really weird.
The appropriations bill that includes NIH is being finalized.

The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.

The House version does not and OMB has issued a veto threat if the House includes such language.

1/3
a close up of a brown surface with a few spots
ALT: a close up of a brown surface with a few spots
media.tenor.com
January 14, 2026 at 5:40 PM
Reposted by Jeff Lewis
This the ask for the NIH budget. Multi year funding (MYF) has an important role for some funding mechanisms but this regime wants to expand MYF and that will have disastrous consequences for how many grants get funded. MYF should be limited to how it was used in 2024.
Ask: keep the senate language that limits MYF to FY2024 levels.
January 14, 2026 at 4:40 PM
Reposted by Jeff Lewis
Multiyear funding q. Volkow confirms 50% time. Very concerned. Especially for younger investigators. Nothing about how NIDA Blew it off last year. Koob- dramatic cut to success rate. Mentions 36% hit but unclear on what he meant.
January 12, 2026 at 6:51 PM
Reposted by Jeff Lewis
I have been modeling the impact of multi-year funding.

Based on fairly reasonable assumptions, 50% multi-year funding, the number of new and competing awards is anticipated to drop to approximately 6000 compared to 10,000 had there been no multi-year funding above the historical background rate.
January 13, 2026 at 1:51 PM
Reposted by Jeff Lewis
Guys. It's time for some game theory.

Let's assume your manuscript is ready to go, and your competitor is weeks behind. Your choices:

1/You preprint your manuscript. You have an independent, public record of priority. There's always proof that you were first.
I absolutely agree with you -- but what I'm told is "my competitor will see my preprint and replicate/rush their story to a journal" 😬
And I know that this has indeed happened, but it seems to be extremely rare and, you know, I prefer to be scooped with a preprint than without one 😅
January 12, 2026 at 5:36 PM
Reposted by Jeff Lewis
Other are bringing this up but we always have to ask: WHO are we talking about when we say “Science is doing okay?”

Science is NOT just about how much funding gets allocate, it is about WHO is getting funded. The staffing issues and changing policies are STILL affecting THOSE decisions
This is a HUGE win…and one that happened because we ~collectively~ said “NO!”

But AAAS coming in and saying on record to the NYT “Science is doing ok. Things are not bad at all…” is baffling.

If things are hard for you as a scientist, please share in the comments.

www.nytimes.com/2026/01/10/s...
Congress Is Reversing Trump’s Steep Budget Cuts to Science
www.nytimes.com
January 10, 2026 at 8:17 PM
Reposted by Jeff Lewis
Or what structural issues interfered with making changes so we can discuss whether they are important checks or actual roadblocks to be removed
January 10, 2026 at 4:49 PM
Reposted by Jeff Lewis
I would like to see an interviewer follow every descriptive point from Lauer with direct questions about what he did and did not do to address each problem.
January 10, 2026 at 4:37 PM