Metabo_Dave
@metabodave.bsky.social
Mourning the days when all we talked about was font choice, reference styles and glam humping.
Reposted by Metabo_Dave
I have heard through the grapevine that the January Council will be rescheduled
November 25, 2025 at 9:04 PM
I have heard through the grapevine that the January Council will be rescheduled
Reposted by Metabo_Dave
My grants that did not get reviewed in October due to the shutdown will now be reviewed at the end of January. I think this means they'll miss the January 2026 Council - anyone have any insights into how this will be dealt with? Lumped into May Council? That's going to screw us
November 24, 2025 at 1:41 PM
My grants that did not get reviewed in October due to the shutdown will now be reviewed at the end of January. I think this means they'll miss the January 2026 Council - anyone have any insights into how this will be dealt with? Lumped into May Council? That's going to screw us
NIH FY26 might be worse than FY25.
We have a CR and the NIH still citing the presidents budget request, an unofficial multi year funding mandate, apparently no paylines, IC leadership turnover, continued OMB/Vought interference, more shutdowns likely
This is a recipe for total paralysis.
We have a CR and the NIH still citing the presidents budget request, an unofficial multi year funding mandate, apparently no paylines, IC leadership turnover, continued OMB/Vought interference, more shutdowns likely
This is a recipe for total paralysis.
November 24, 2025 at 1:44 PM
NIH FY26 might be worse than FY25.
We have a CR and the NIH still citing the presidents budget request, an unofficial multi year funding mandate, apparently no paylines, IC leadership turnover, continued OMB/Vought interference, more shutdowns likely
This is a recipe for total paralysis.
We have a CR and the NIH still citing the presidents budget request, an unofficial multi year funding mandate, apparently no paylines, IC leadership turnover, continued OMB/Vought interference, more shutdowns likely
This is a recipe for total paralysis.
Reposted by Metabo_Dave
Posting for no particular reason….
From the Archive: Comparing performance of within-payline and "select pay" pickup NIH grants at NIAID drugmonkey.wordpress.com/2011/10/26/c...
From the Archive: Comparing performance of within-payline and "select pay" pickup NIH grants at NIAID drugmonkey.wordpress.com/2011/10/26/c...
Comparing performance of within-payline and "select pay" pickup NIH grants at NIAID
Well, well, well. How timely. We were just discussing the situation in which some ICs of the NIH fund some subset of their grant applications out of the order of initial peer review. And what shoul…
drugmonkey.wordpress.com
November 22, 2025 at 6:13 PM
Posting for no particular reason….
From the Archive: Comparing performance of within-payline and "select pay" pickup NIH grants at NIAID drugmonkey.wordpress.com/2011/10/26/c...
From the Archive: Comparing performance of within-payline and "select pay" pickup NIH grants at NIAID drugmonkey.wordpress.com/2011/10/26/c...
This is awesome as long my grant gets paid.
November 22, 2025 at 6:04 AM
This is awesome as long my grant gets paid.
Which poor person or immigrant will they find to put in jail for this?
EPSTEIN BOMBSHELL: my staff is releasing a new report showing JPMorgan Chase executives – all the way to the top – enabled Epstein's sex trafficking operation. You're going to want to read this.
Wyden Presses for Investigation Into JPMorgan Chase and Epstein
www.nytimes.com
November 20, 2025 at 4:41 PM
Which poor person or immigrant will they find to put in jail for this?
I'll be glad when the word "effectuate" is permanently removed from my memory.
Update on a significant development NIH grant terms.
On 10/1, a change to grant making regs went into effect that gives NIH more power to terminate grants for policy reasons.
But to use this power, new grant terms must include specific language. See @aniloza.bsky.social w/ the story from July.
1/
On 10/1, a change to grant making regs went into effect that gives NIH more power to terminate grants for policy reasons.
But to use this power, new grant terms must include specific language. See @aniloza.bsky.social w/ the story from July.
1/
HHS devises legal playbook for future grant terminations, internal memo shows
Exclusive: HHS devises a legal playbook for future research grant terminations, an internal memo shows.
www.statnews.com
November 20, 2025 at 4:25 PM
I'll be glad when the word "effectuate" is permanently removed from my memory.
Reposted by Metabo_Dave
The same thing happened during the 35 day shutdown. We rescheduled our late October meeting for Dec 19-20. We did 50 To 60% ND. It was a pain but not impossible. The 70% ND seems reasonable because reviewers can always call for discussion. IOW this is really not unprecedented.
November 15, 2025 at 10:03 PM
The same thing happened during the 35 day shutdown. We rescheduled our late October meeting for Dec 19-20. We did 50 To 60% ND. It was a pain but not impossible. The 70% ND seems reasonable because reviewers can always call for discussion. IOW this is really not unprecedented.
Reposted by Metabo_Dave
NIH is chaos. USDA is chaos. It looks like we put all the effort into wrapping a grant in proper shape and form, and now they've extended the deadlines.
November 15, 2025 at 2:53 PM
NIH is chaos. USDA is chaos. It looks like we put all the effort into wrapping a grant in proper shape and form, and now they've extended the deadlines.
Reposted by Metabo_Dave
NIH has never changed deadlines before - just allowed late submissions (eg, could allow PIs to use Continuous Submission deadline). Sit tight, leave your app there - none will be withdrawn. The loss of institutional expertise is obvious in this “Notice” (& in more ways than updated deadline).
November 15, 2025 at 1:31 PM
NIH has never changed deadlines before - just allowed late submissions (eg, could allow PIs to use Continuous Submission deadline). Sit tight, leave your app there - none will be withdrawn. The loss of institutional expertise is obvious in this “Notice” (& in more ways than updated deadline).
What if you have already submitted a grant in Oct/Nov? Will it be withdrawn?
Doesn't this mean that the entire cycle has effectively been cancelled?
What a nightmare.
Doesn't this mean that the entire cycle has effectively been cancelled?
What a nightmare.
NIH grant applicants:
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD.
grants.nih.gov/grants/guide...
NOT-OD-26-005: Interim Guidance on Reopening of NIH Extramural Activities
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Interim Guidance on Reopening of NIH Extramural Activities NOT-OD-26-005. NIH
grants.nih.gov
November 15, 2025 at 1:06 PM
What if you have already submitted a grant in Oct/Nov? Will it be withdrawn?
Doesn't this mean that the entire cycle has effectively been cancelled?
What a nightmare.
Doesn't this mean that the entire cycle has effectively been cancelled?
What a nightmare.
If paylines stay around 5%ile for some ICs, this might save everyone a lot of time. You can meet for a few hours in the morning and be done with the grants that even have a chance at being picked up.
With a shutdown likely end of Jan, the NIH will struggle to spend it's appropriations this FY.
With a shutdown likely end of Jan, the NIH will struggle to spend it's appropriations this FY.
Just got an email from my SRO for the study section that was missed in October. Good news is that they are trying to reschedule ASAP (Dec/Jan). The bad news is that CSR is mandating that only the the top third (not half) of applications will get discussed for the next 2 rounds.
November 14, 2025 at 7:21 PM
If paylines stay around 5%ile for some ICs, this might save everyone a lot of time. You can meet for a few hours in the morning and be done with the grants that even have a chance at being picked up.
With a shutdown likely end of Jan, the NIH will struggle to spend it's appropriations this FY.
With a shutdown likely end of Jan, the NIH will struggle to spend it's appropriations this FY.
Reposted by Metabo_Dave
The gift that keeps on giving.
Epstein’s brother Mark asking Steve Bannon if Putin has “the photo of Trump blowing Bubba” - or Bill Clinton to the rest of us.
Epstein’s brother Mark asking Steve Bannon if Putin has “the photo of Trump blowing Bubba” - or Bill Clinton to the rest of us.
![Mark L. Epstein
3/21/20182:54:13 PM
jeffreyE. [jeevacation@gmail.com]
RE: hey
Importance: High
I'd rather be in Donni Dee's shoes.
From: jeffrey E. [mailto:jeevacation@gmail.com]
Sent: Wednesday, March 21, 2018 10:43 AM
To: Mark L. Epstein
Subject: Re: hey
you mean DONNI TEE
On Wed, Mar 21, 2018 at 9:54 AM, Mark L. Epstein
You and your boy Donnie can make a remake of the movie Get Hard.
Sent via tin can and string.
On Mar 21, 2018, at 09:37, jeffrey E. <jeevacation@gmail.com> wrote:
and i thought- I had tsuris
wrote:
On Wed, Mar 21, 2018 at 4:32 AM, Mark L. Epstein
Ask him if Putin has the photos of Trump blowing Bubba?
wrote:
From: jeffrey E. [mailto:jeevacation@gmail.com]
Sent: Monday, March 19, 2018 2:15 PM
To:
Subject: Re: hey
All good. Bannon with me
On Mon, Mar 19, 2018 at 1:49 PM Mark L. Epstein
How are you doing?
wrote:
A while back you mentioned that you were prediabetic. Has anything changed with that?
What is your boy Donald up to now?](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:movn6xzezospl7lnkhy7nzpt/bafkreig2xevke2levnhnq2boozm6o6pcawf4ysup5vff5iv47f3m76lkwm@jpeg)
November 14, 2025 at 7:02 PM
The gift that keeps on giving.
Epstein’s brother Mark asking Steve Bannon if Putin has “the photo of Trump blowing Bubba” - or Bill Clinton to the rest of us.
Epstein’s brother Mark asking Steve Bannon if Putin has “the photo of Trump blowing Bubba” - or Bill Clinton to the rest of us.
Oh oh
In between things I've been checking in on the emails that mention "university" and uhh did we all know about this connection?
![Screenshot from the Epstein Document Search which reads: House_Oversight_029401
From: Donald Rubin
Sent: 1/22/2017 7:31:32 PM
To: jeffrey E. [jeeyacation@gmail.com]
Subject: Republican health care experts dismiss Donald Trump's ideas
Importance: High
https://www.statnews.com/20 1 6/03/04/trump -repub cans-health-care/? s camp aign=trendmd
Jeffrey,
This cannot be true, can it? This guy must be as dumb about this stuff as a tampon laced with arsenic!!
HELP!
Great meeting yesterday — really enjoyed it.
And happy birthday again, Don
Donald B. Rubin
John L. Loeb Professor of Statistics
Department of Statistics, Harvard University
1 Oxford Street
Cambridge MA 02138
HOUSE OVERSIGHT 029401](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ozma3timm5c32fa7bimb4zaj/bafkreiezajc6f2rgwxrdx2242izbelpumkgdruc52pzu236rhovlcyfmde@jpeg)
November 13, 2025 at 6:48 PM
Oh oh
Reposted by Metabo_Dave
Responding to a 2017 message that Trump was 'so gross', Jeffrey Epstein said Trump was "worse in real life and upclose."
November 12, 2025 at 8:40 PM
Responding to a 2017 message that Trump was 'so gross', Jeffrey Epstein said Trump was "worse in real life and upclose."
Reposted by Metabo_Dave
Every Democratic senator who votes for this should be primaried.
Deal has been reached, I’m told by multiple sources, and Kaine has announced his support
November 10, 2025 at 12:16 AM
Every Democratic senator who votes for this should be primaried.
A CR until January 30th at FY24 levels will mean continued ultra conservative funding policies at the NIH. Expect the MYF "policy" to continue too. Not a great scenario considering the appropriations bills on the table look promising.
November 10, 2025 at 1:06 AM
A CR until January 30th at FY24 levels will mean continued ultra conservative funding policies at the NIH. Expect the MYF "policy" to continue too. Not a great scenario considering the appropriations bills on the table look promising.
Democrats man. What a bunch of twats.
November 10, 2025 at 12:53 AM
Democrats man. What a bunch of twats.
Reposted by Metabo_Dave
RFK Jr's response to someone collapsing nearby him was to haul ass out of the room as quickly as possible
November 6, 2025 at 5:45 PM
RFK Jr's response to someone collapsing nearby him was to haul ass out of the room as quickly as possible
Reposted by Metabo_Dave
I saw it in the Principled Investigator Substack, and they reference a Science article that notes an NIH presentation. open.substack.com/pub/theprinc...
The Principled Investigator - October 31, 2025
Weekly digest
open.substack.com
November 6, 2025 at 2:10 AM
I saw it in the Principled Investigator Substack, and they reference a Science article that notes an NIH presentation. open.substack.com/pub/theprinc...
Reposted by Metabo_Dave
and there it is. the absolutely massive change in R01s funded multi-year. our perceptions that the new mandate, sorry strong suggestion, has had a dramatic effect on forward funding and therefore success rates is validated.
2025
Here the largest fraction is for R01 awards, followed by RF1s, and R21s.
In most cases, these were R01s that had not particularly reason to be forward funded except that NIH had put itself in a situation when large amounts of funding needed to be committed by the end of the fiscal year
21/25
Here the largest fraction is for R01 awards, followed by RF1s, and R21s.
In most cases, these were R01s that had not particularly reason to be forward funded except that NIH had put itself in a situation when large amounts of funding needed to be committed by the end of the fiscal year
21/25
November 5, 2025 at 4:45 PM
and there it is. the absolutely massive change in R01s funded multi-year. our perceptions that the new mandate, sorry strong suggestion, has had a dramatic effect on forward funding and therefore success rates is validated.
Reposted by Metabo_Dave
This rough estimate says FY2025 new R01s should be down by about 26%. If we look at the number actually funded in FY2025, it is down 25% from FY2024, 32% from FY2023 and 34% down from FY2022.
reporter.nih.gov/search/OrznV...
reporter.nih.gov/search/OrznV...
RePORT ⟩ RePORTER
reporter.nih.gov
November 5, 2025 at 5:39 PM
This rough estimate says FY2025 new R01s should be down by about 26%. If we look at the number actually funded in FY2025, it is down 25% from FY2024, 32% from FY2023 and 34% down from FY2022.
reporter.nih.gov/search/OrznV...
reporter.nih.gov/search/OrznV...
A government shutdown with specific carve outs is the most pathetic thing I've heard from Congress. The media is desperately trying to push the narrative that Democrats are under intense pressure, but I don't see that at all. The message is simple: the Rs have complete control.
October 29, 2025 at 3:09 PM
A government shutdown with specific carve outs is the most pathetic thing I've heard from Congress. The media is desperately trying to push the narrative that Democrats are under intense pressure, but I don't see that at all. The message is simple: the Rs have complete control.
Reposted by Metabo_Dave
Nature Comms was cleverly positioned as a trickle down for subfields without their own Nature sibling but in practice took papers from high-impact fields that did. 2/2
October 29, 2025 at 2:05 AM
Nature Comms was cleverly positioned as a trickle down for subfields without their own Nature sibling but in practice took papers from high-impact fields that did. 2/2
If a journal that used to occupy that space has a much lower IF and **perceived** prestige, but requires similar data and "conceptual advance" (ugh), then it's a no brainer.
IMO these journals have generally failed to adapt to the new Nat Comms et al driven landscape.
IMO these journals have generally failed to adapt to the new Nat Comms et al driven landscape.
Nature Communications will publish ~10K papers in 2025 pubmed.ncbi.nlm.nih.gov?term=%22Natu...
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
October 28, 2025 at 6:37 PM
If a journal that used to occupy that space has a much lower IF and **perceived** prestige, but requires similar data and "conceptual advance" (ugh), then it's a no brainer.
IMO these journals have generally failed to adapt to the new Nat Comms et al driven landscape.
IMO these journals have generally failed to adapt to the new Nat Comms et al driven landscape.