Prasad Jallepalli, MD, PhD
@prasad.bsky.social
Prof & Lab Head in NYC. 100% research: cell division, genome integrity, cancer.
Curious to a fault. Also πολύτροπος. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.
Curious to a fault. Also πολύτροπος. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.
Reposted by Prasad Jallepalli, MD, PhD
Today we won.
A U.S. District Court ruled that the administration violated federal law when it secretly convened a group of climate contrarians to produce a thoroughly debunked report to overturn the Endangerment Finding.
The science still matters. We won't stop.
www.nytimes.com/2026/01/30/c...
A U.S. District Court ruled that the administration violated federal law when it secretly convened a group of climate contrarians to produce a thoroughly debunked report to overturn the Endangerment Finding.
The science still matters. We won't stop.
www.nytimes.com/2026/01/30/c...
A Secret Panel to Question Climate Science Was Unlawful, Judge Rules
www.nytimes.com
January 31, 2026 at 2:26 AM
Today we won.
A U.S. District Court ruled that the administration violated federal law when it secretly convened a group of climate contrarians to produce a thoroughly debunked report to overturn the Endangerment Finding.
The science still matters. We won't stop.
www.nytimes.com/2026/01/30/c...
A U.S. District Court ruled that the administration violated federal law when it secretly convened a group of climate contrarians to produce a thoroughly debunked report to overturn the Endangerment Finding.
The science still matters. We won't stop.
www.nytimes.com/2026/01/30/c...
“Although many people feel strongly about this (exhibit) one way, other people may disagree or feel strongly another way,” said [the AUSA]. “Ultimately the govt. gets to choose the message it wants to convey.”
Judge: “That is a dangerous statement you are making. It is horrifying to listen to."
Judge: “That is a dangerous statement you are making. It is horrifying to listen to."
A federal judge warned Justice Department lawyers that their statements on a slavery exhibit display in Philadelphia were "horrifying."
"You can’t erase history once you’ve learned it. It doesn’t work that way"
"You can’t erase history once you’ve learned it. It doesn’t work that way"
Judge Calls DOJ's Statements On Slavery Exhibit Display 'Dangerous' And 'Horrifying'
Senior U.S. District Judge Cynthia Rufe told the Justice Department's attorneys, "“You can’t erase history once you’ve learned it. It doesn’t work that way.”
www.huffpost.com
January 31, 2026 at 6:27 AM
“Although many people feel strongly about this (exhibit) one way, other people may disagree or feel strongly another way,” said [the AUSA]. “Ultimately the govt. gets to choose the message it wants to convey.”
Judge: “That is a dangerous statement you are making. It is horrifying to listen to."
Judge: “That is a dangerous statement you are making. It is horrifying to listen to."
Reposted by Prasad Jallepalli, MD, PhD
Trump administration officials have falsely linked Alex Pretti and Renee Macklin Good to domestic terrorism. It's part of a larger pattern by the Department of Homeland Security. n.pr/45Arnsg
DHS keeps making false claims about people. It's part of a broader pattern
Trump administration officials have falsely linked Alex Pretti and Renee Macklin Good to domestic terrorism. It's part of a larger pattern by the Department of Homeland Security.
n.pr
January 31, 2026 at 6:10 AM
Trump administration officials have falsely linked Alex Pretti and Renee Macklin Good to domestic terrorism. It's part of a larger pattern by the Department of Homeland Security. n.pr/45Arnsg
18½ minutes of this cure were tried in the 1970s but to no avail
“Doctors won’t tell you this, but you don’t need medication for a tapeworm—all you need is the natural power of friction,” Robert F. Kennedy Jr. said as he dropped to the floor, lifted his legs high, and dragged his ass along the White House carpet during a press conference.
RFK Jr. Demonstrates How To Remove Tapeworm By Scooting Ass Across Carpet
WASHINGTON—In an address touting the practice as a completely drug-free method to relieve the common affliction, Secretary of Health and Human Services Robert F. Kennedy Jr. demonstrated Thursday how ...
theonion.com
January 31, 2026 at 5:41 AM
18½ minutes of this cure were tried in the 1970s but to no avail
there are devils who walk amongst us
Jesus Christ
January 31, 2026 at 5:21 AM
there are devils who walk amongst us
Reposted by Prasad Jallepalli, MD, PhD
This post is blowing up, so for all the big name journos sharing it, some context:
This was a rally in Chicago explicitly calling for ICE to be abolished, and for a mass general strike to counter the Trump admin's continous attacks on our communities and civil liberties.
This was a rally in Chicago explicitly calling for ICE to be abolished, and for a mass general strike to counter the Trump admin's continous attacks on our communities and civil liberties.
It's near-white out conditions in Chicago as the snow comes down, and tonight's anti-ICE/CBP rally is wrapping up in front of city hall.
But not before the crowd bounces and chants, "I believe that we will win!"
But not before the crowd bounces and chants, "I believe that we will win!"
January 31, 2026 at 1:30 AM
This post is blowing up, so for all the big name journos sharing it, some context:
This was a rally in Chicago explicitly calling for ICE to be abolished, and for a mass general strike to counter the Trump admin's continous attacks on our communities and civil liberties.
This was a rally in Chicago explicitly calling for ICE to be abolished, and for a mass general strike to counter the Trump admin's continous attacks on our communities and civil liberties.
Reposted by Prasad Jallepalli, MD, PhD
The Senate passed a measure to avert a shutdown on Friday. But with the House on recess, funding for broad stretches of the federal government has technically lapsed. n.pr/4q5pbQJ
What to know about the partial government shutdown
The Senate passed a measure to avert a shutdown on Friday. But with the House on recess, funding for broad stretches of the federal government has technically lapsed.
n.pr
January 31, 2026 at 5:05 AM
The Senate passed a measure to avert a shutdown on Friday. But with the House on recess, funding for broad stretches of the federal government has technically lapsed. n.pr/4q5pbQJ
Reposted by Prasad Jallepalli, MD, PhD
CLOSING SOON: Applications for Group Leader roles at our Janelia Research Campus close Feb. 3! Have original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & beyond? Learn more: janelia.org/groupleader 🧪
January 30, 2026 at 6:16 PM
CLOSING SOON: Applications for Group Leader roles at our Janelia Research Campus close Feb. 3! Have original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & beyond? Learn more: janelia.org/groupleader 🧪
Reposted by Prasad Jallepalli, MD, PhD
Minnesota is giving us hope. This is nurses+++ today outside one of our local hospitals in Anchorage, Alaska, honoring Alex Petti and Rene Good. From coast to coast, we will prove that only love can conquer hate. And that is what this is fear and hate. #StandUPAlaska. www.adn.com/politics/202...
‘Heartbroken and furious’: Anchorage nurses and students protest ICE actions
Health care workers say they were galvanized to speak out after federal agents shot and killed intensive care nurse Alex Pretti in Minnesota.
www.adn.com
January 31, 2026 at 4:54 AM
Minnesota is giving us hope. This is nurses+++ today outside one of our local hospitals in Anchorage, Alaska, honoring Alex Petti and Rene Good. From coast to coast, we will prove that only love can conquer hate. And that is what this is fear and hate. #StandUPAlaska. www.adn.com/politics/202...
IANAL but (2) seems to allow arrest of legally present aliens, since the subjective belief of the arresting officer is sufficient
January 31, 2026 at 4:45 AM
IANAL but (2) seems to allow arrest of legally present aliens, since the subjective belief of the arresting officer is sufficient
"The memo, addressed to all ICE personnel and signed on Wednesday by Mr. Lyons, centers on a federal law that empowers agents to make warrantless arrests of people they believe are undocumented immigrants, if they are 'likely to escape' before an arrest warrant can be obtained."
day by day, we are creeping closer to de facto enactment of the Fugitive Slave Act of 1850
January 31, 2026 at 4:25 AM
"The memo, addressed to all ICE personnel and signed on Wednesday by Mr. Lyons, centers on a federal law that empowers agents to make warrantless arrests of people they believe are undocumented immigrants, if they are 'likely to escape' before an arrest warrant can be obtained."
day by day, we are creeping closer to de facto enactment of the Fugitive Slave Act of 1850
January 31, 2026 at 4:23 AM
day by day, we are creeping closer to de facto enactment of the Fugitive Slave Act of 1850
Reposted by Prasad Jallepalli, MD, PhD
Scoop: Federal agents were told this week that they have broader power to arrest people without a warrant, according to an internal Immigration and Customs Enforcement memo reviewed by The New York Times.
www.nytimes.com/2026/01/30/u...
www.nytimes.com/2026/01/30/u...
ICE Expands Power of Agents to Arrest People Without Warrants
www.nytimes.com
January 31, 2026 at 12:39 AM
Scoop: Federal agents were told this week that they have broader power to arrest people without a warrant, according to an internal Immigration and Customs Enforcement memo reviewed by The New York Times.
www.nytimes.com/2026/01/30/u...
www.nytimes.com/2026/01/30/u...
Reposted by Prasad Jallepalli, MD, PhD
I'm no expert in politics, but this vote shows the crucial importance of party discipline and solidarity in achieving what we all want
Very important vote. It makes repealing ICE surge funding the mainstream position in the party, with bipartisan support.
👀 Every Senate Democrat + Collins and Murkowski just voted for the Bernie Sanders amendment to repeal the $75 billion in additional ICE funding under Trump’s “big beautiful bill.” The measure failed 49-51.
January 31, 2026 at 4:06 AM
I'm no expert in politics, but this vote shows the crucial importance of party discipline and solidarity in achieving what we all want
Reposted by Prasad Jallepalli, MD, PhD
Very important vote. It makes repealing ICE surge funding the mainstream position in the party, with bipartisan support.
👀 Every Senate Democrat + Collins and Murkowski just voted for the Bernie Sanders amendment to repeal the $75 billion in additional ICE funding under Trump’s “big beautiful bill.” The measure failed 49-51.
January 30, 2026 at 11:26 PM
Very important vote. It makes repealing ICE surge funding the mainstream position in the party, with bipartisan support.
Reposted by Prasad Jallepalli, MD, PhD
I heard a lot of similar stories last year, and more this year. Lots of 4th rotations. This is devastating for the future of science. We reject many superb applicants to PhD programs every year, because spots are limited. Now we struggle to find labs for admitted students.
A biochemistry student at Stanford said 6 to 10 labs told her they’re not sure they’d have funds to accept a new student. She has reached out to 30 to 40 labs in total. She keeps a list on labs she’s heard good things about & if they’re taking students. Barsouk checks those notes every other day.
January 31, 2026 at 1:37 AM
I heard a lot of similar stories last year, and more this year. Lots of 4th rotations. This is devastating for the future of science. We reject many superb applicants to PhD programs every year, because spots are limited. Now we struggle to find labs for admitted students.
Reposted by Prasad Jallepalli, MD, PhD
🚨"My mom is being arrested for documenting what happened at City Church—this is wrong. This goes against her first amendment right. She is not a protester, she is not an activist, she is a mom working to provide for her children,"-daughter of arrested journalist @bygeorgiafort.bsky.social
January 30, 2026 at 8:45 PM
🚨"My mom is being arrested for documenting what happened at City Church—this is wrong. This goes against her first amendment right. She is not a protester, she is not an activist, she is a mom working to provide for her children,"-daughter of arrested journalist @bygeorgiafort.bsky.social
Reposted by Prasad Jallepalli, MD, PhD
Thousands of people filled the streets of downtown Minneapolis in protest of federal immigration enforcement for the second consecutive Friday.
📷️: Aaron Lavinsky
📷️: Aaron Lavinsky
January 30, 2026 at 9:42 PM
Thousands of people filled the streets of downtown Minneapolis in protest of federal immigration enforcement for the second consecutive Friday.
📷️: Aaron Lavinsky
📷️: Aaron Lavinsky
Reposted by Prasad Jallepalli, MD, PhD
To summarize:
Most important
Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified.
He was part of an organized team working on this problem. He got lots of help.
11/14
Most important
Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified.
He was part of an organized team working on this problem. He got lots of help.
11/14
January 30, 2026 at 7:58 PM
To summarize:
Most important
Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified.
He was part of an organized team working on this problem. He got lots of help.
11/14
Most important
Max Perutz was NOT an example of someone with a great idea who went against the establishment wisdom to solve an important problem that he had uniquely identified.
He was part of an organized team working on this problem. He got lots of help.
11/14
🧵
Director Bhattacharya told a story about Max Perutz to illustrate the challenges for young investigators.
He said that Max was a young scientist working on the structure of myoglobin at the University of Cambridge.
2/14
He said that Max was a young scientist working on the structure of myoglobin at the University of Cambridge.
2/14
January 30, 2026 at 8:07 PM
🧵
Reposted by Prasad Jallepalli, MD, PhD
"The MAHA Institute is led by veterans of Team Kennedy and the American Values Super PAC. We helped fund and lead Robert F. Kennedy Jr.’s 2024 campaign"
www.globenewswire.com/news-release...
www.globenewswire.com/news-release...
MAHA Institute Launches to Support Trump-Kennedy Health Agenda and Commission Report
Following its successful launch on May 15, featuring the highly-anticipated “MAHA Commission Report” spearheaded by the Health and Human Services...
www.globenewswire.com
January 30, 2026 at 6:48 PM
"The MAHA Institute is led by veterans of Team Kennedy and the American Values Super PAC. We helped fund and lead Robert F. Kennedy Jr.’s 2024 campaign"
www.globenewswire.com/news-release...
www.globenewswire.com/news-release...
🧵
The visual of NIH leadership alone is arresting. They are all sitting in front of MAHA (TM) Institute signs. It's a trademark. That's like them sitting in front of coca cola signs. It's streamed on Real America's Voice, a channel that has videos with Qanon tags
en.wikipedia.org/wiki/Real_Am...
en.wikipedia.org/wiki/Real_Am...
January 30, 2026 at 8:06 PM
🧵
Reposted by Prasad Jallepalli, MD, PhD
at some level i treat AI code like a physical system. i use experiments and controls to make sure it's behaving the way i expect.
things I'm constantly doing:
1. smoke tests to make sure code runs
2. sanity checks with expected outputs
3. extensive testing (auto and manual)
4. modular building
things I'm constantly doing:
1. smoke tests to make sure code runs
2. sanity checks with expected outputs
3. extensive testing (auto and manual)
4. modular building
The entire piece is worthwhile, but the section stands out and fits with my own experience and perspective
January 30, 2026 at 7:33 PM
at some level i treat AI code like a physical system. i use experiments and controls to make sure it's behaving the way i expect.
things I'm constantly doing:
1. smoke tests to make sure code runs
2. sanity checks with expected outputs
3. extensive testing (auto and manual)
4. modular building
things I'm constantly doing:
1. smoke tests to make sure code runs
2. sanity checks with expected outputs
3. extensive testing (auto and manual)
4. modular building
Reposted by Prasad Jallepalli, MD, PhD
Macaulay Culkin pays tribute to his on-screen mother Catherine O’Hara:
“Mama. I thought we had time. I wanted more. I wanted to sit in a chair next to you. I heard you. But I had so much to say. I love you. I'll see you later.”
“Mama. I thought we had time. I wanted more. I wanted to sit in a chair next to you. I heard you. But I had so much to say. I love you. I'll see you later.”
January 30, 2026 at 7:26 PM
Macaulay Culkin pays tribute to his on-screen mother Catherine O’Hara:
“Mama. I thought we had time. I wanted more. I wanted to sit in a chair next to you. I heard you. But I had so much to say. I love you. I'll see you later.”
“Mama. I thought we had time. I wanted more. I wanted to sit in a chair next to you. I heard you. But I had so much to say. I love you. I'll see you later.”