Three theories could explain why the North American H5N1 epidemic has not been more deadly

Abstract. Glycoproteins cover the surface of enveloped viruses such as herpes simplex virus 1 (HSV-1). Whilst essential for cellular attachment and entry,

Scientists, research institutions, funders, libraries and publishers must all improve software practices.

Protein ubiquitination regulates cell biology through diverse avenues, from quality control-linked protein degradation to signaling functions such as modulating protein-protein interactions and enzyme...

Vimig, defined as “virus-induced migrasome,” represents a novel class of extracellular vesicles that originate from virus-infected cells. The mechanisms underlying vimig formation involve actin remode...

Despite billions of passerines seasonally migrating during the night at high altitudes, only three bat species have been found to consistently tap into this rich prey resource. However, it remains unk...

Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that naked mole-rat cyclic guanosine monophosphate–adenosine ...

In mammalian cells, RNA species make up ∼10% of chromatin by mass and play a structural role in the nucleus by acting as scaffolds and influencing gen…

Characterization of dipeptidase 1 as a receptor for porcine haemagglutinating encephalomyelitis virus reveals the versatility of embecovirus receptor binding domains and receptor usage.

Pathogens were a major driver of genetic adaptation during human evolution. Viruses in particular were a dominant driver of adaptation in the thousands of proteins that physically interact with viruse...

Interferon-inducible Myxovirus resistance 1 (MX1) proteins are known to restrict influenza A virus (IAV) transcription/replication process. Herein,...

Outbreaks of zoonotic viruses in human populations highlight the need to understand the molecular factors that influence viral host tropism and interspecies transmission. A virus’s host range is deter...

Alphacoronaviruses are in the family Coronaviridae, along with three other genera; beta, gamma, and deltacoronaviruses. The Alphacoronavirus genus consists of viruses that infect a wide range of hosts...

Outlining the trial-and-error processes that are involved in every research project could help others to become more efficient and paint a more honest picture of life as a researcher.

The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...

Enteroviruses are a widespread and diverse set of pathogens responsible for over ~1 billion human infections annually. Upon cell entry, translation of the virus genome is mediated by an internal ribos...

In Gasselternijveenschemond (gemeente Aa en Hunze, provincie Drenthe) is vogelgriep vastgesteld op een bedrijf met vleeskuikenouderdieren. Om verspreiding van het virus te voorkomen, worden de circa 7...

Over 20 species of geographically and phylogenetically diverse bird species produce convergent whining vocalizations towards their respective brood parasites. Model presentation and playback experiments across multiple continents suggest that these learned calls provoke an innate response even among allopatric species.

In contrast to living organisms, viruses were long thought to lack protein synthesis machinery and instead depend on host factors to translate viral transcripts. Here, we discover that giant DNA virus...

Epstein–Barr virus is associated with cancer and implicated in autoimmune diseases. Three studies reveal desmocollin 2 and R9AP as receptors for Epstein–Barr virus infection, highlighting new avenues for targeted therapies.